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The map label for this gene is argJ

Identifier: 23502791

GI number: 23502791

Start: 1871430

End: 1872671

Strand: Reverse

Name: argJ

Synonym: BR1941

Alternate gene names: 23502791

Gene position: 1872671-1871430 (Counterclockwise)

Preceding gene: 23502792

Following gene: 23502790

Centisome position: 88.85

GC content: 60.95

Gene sequence:

>1242_bases
ATGTCCGCGTCCGTTTCTCCGCTCGCTCCCAAACACTACCCCGCCATGCCGGTCATTCATGGCGTGCGCATCGCCACAGC
AGCAGCCGGTATCAAATATAAGGGGCGAACGGATCTGATGCTGATGGTGTTCGATCGCCCGGCAGAAGCCGCGGGCGTTT
TCACCCGTTCGCTGTGCCCCTCGGCGCCGGTTGATTTCTGCCGCCGCAATCTCGTGCATGGCAAGGCGCGCGCGGTCGTG
GTCAATTCGGGCAATGCCAATGCCTTTACCGGCCTTAAAGGCCGCGAGGCGACGCAAGCGACGGCGGAAGCTGCTGCAAA
AGCCATTGGCTGCGCCACGACCGATATATTCCTCGCTTCGACCGGCGTGATCGGCGAGCCGCTCGATGCTGGCAAATTCT
CGCACCTTCTGGGCGATATGGCGGAAAGCGCGACGGAAGATTTCTGGACCGAAGCCGCCAAGGCGATCATGACAACCGAT
ACCTATCCGAAAGTGGCGACCGAAACGGTGCTGCTCGGTCAGGTTCCGGTCACGATCAATGGTATCGCCAAGGGTGCGGG
CATGATCGCGCCCGATATGGCGACGATGCTTTCCTTTGTCGTCACCGATGCGCCTATCAAGGCCGATGCGCTCCAGAGCC
TTTTGTCGAAGGGCGTCGGCTCAACCTTCAATTCCGTGACGGTCGATAGCGATACATCCACCTCCGATACGCTGATGCTG
TTTGCAACCGGAACGGCTGCCGAGCGCGGCGCGCCCGAAATCACCGATGCCGCCGACAAACGCCTTGCTGATTTCAAGAA
GGCGCTGGGGCGTGTGCTGAAATCGCTGGCGCTTCAAGTGGTGCGCGACGGCGAAGGCGCGCGCAAGATGGTGGAGGTCG
AAGTGACCGGTGCGAAGTCTGCCGCCTCCGCCAAGAAGATTGCACTTTCCATTGCCAATTCGCCGCTGGTCAAGACGGCC
GTTGCCGGTGAAGATGCCAATTGGGGCCGTGTGGTCATGGCGGTCGGCAAGGCTGGCGAACCGGCCGACCGCGACCGCCT
CGCCATCTGGTTCGGCGATATTCGCGTGGCGCATCAGGGCGAGCGGGACCCGGCCTATTCGGAAGACGCCACCTCCGCCT
ATATGGAGGGCGAAGATATTCGCATCCGCGTCGATCTTGGCATTGGTCGCGGCAAGGCAACTGTGTGGACATGTGATCTG
ACGAAGGAATATGTGGCCATTAACGGCGATTATCGCAGCTAG

Upstream 100 bases:

>100_bases
TGATTTTATGCAGCAAACCTTTCCAATGCGCGGATCAGGCTTTTGAATCCGCAAATCGGGTTTGCCACACTGGAAACATC
CTATCGCTTTCGAGGCACAT

Downstream 100 bases:

>100_bases
CTTTCGGGCCTGTTAATCCGGTGAGAATGGTGTGAGGCCCTCCGTTCTGACACCGGAATGAGCGGGCGATCTGCCATGTC
TGAGGGGTTTATGGTGCCAG

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MSASVSPLAPKHYPAMPVIHGVRIATAAAGIKYKGRTDLMLMVFDRPAEAAGVFTRSLCPSAPVDFCRRNLVHGKARAVV
VNSGNANAFTGLKGREATQATAEAAAKAIGCATTDIFLASTGVIGEPLDAGKFSHLLGDMAESATEDFWTEAAKAIMTTD
TYPKVATETVLLGQVPVTINGIAKGAGMIAPDMATMLSFVVTDAPIKADALQSLLSKGVGSTFNSVTVDSDTSTSDTLML
FATGTAAERGAPEITDAADKRLADFKKALGRVLKSLALQVVRDGEGARKMVEVEVTGAKSAASAKKIALSIANSPLVKTA
VAGEDANWGRVVMAVGKAGEPADRDRLAIWFGDIRVAHQGERDPAYSEDATSAYMEGEDIRIRVDLGIGRGKATVWTCDL
TKEYVAINGDYRS

Sequences:

>Translated_413_residues
MSASVSPLAPKHYPAMPVIHGVRIATAAAGIKYKGRTDLMLMVFDRPAEAAGVFTRSLCPSAPVDFCRRNLVHGKARAVV
VNSGNANAFTGLKGREATQATAEAAAKAIGCATTDIFLASTGVIGEPLDAGKFSHLLGDMAESATEDFWTEAAKAIMTTD
TYPKVATETVLLGQVPVTINGIAKGAGMIAPDMATMLSFVVTDAPIKADALQSLLSKGVGSTFNSVTVDSDTSTSDTLML
FATGTAAERGAPEITDAADKRLADFKKALGRVLKSLALQVVRDGEGARKMVEVEVTGAKSAASAKKIALSIANSPLVKTA
VAGEDANWGRVVMAVGKAGEPADRDRLAIWFGDIRVAHQGERDPAYSEDATSAYMEGEDIRIRVDLGIGRGKATVWTCDL
TKEYVAINGDYRS
>Mature_412_residues
SASVSPLAPKHYPAMPVIHGVRIATAAAGIKYKGRTDLMLMVFDRPAEAAGVFTRSLCPSAPVDFCRRNLVHGKARAVVV
NSGNANAFTGLKGREATQATAEAAAKAIGCATTDIFLASTGVIGEPLDAGKFSHLLGDMAESATEDFWTEAAKAIMTTDT
YPKVATETVLLGQVPVTINGIAKGAGMIAPDMATMLSFVVTDAPIKADALQSLLSKGVGSTFNSVTVDSDTSTSDTLMLF
ATGTAAERGAPEITDAADKRLADFKKALGRVLKSLALQVVRDGEGARKMVEVEVTGAKSAASAKKIALSIANSPLVKTAV
AGEDANWGRVVMAVGKAGEPADRDRLAIWFGDIRVAHQGERDPAYSEDATSAYMEGEDIRIRVDLGIGRGKATVWTCDLT
KEYVAINGDYRS

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=417, Percent_Identity=38.1294964028777, Blast_Score=243, Evalue=4e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGJ_BRUAB (Q57AV8)

Other databases:

- EMBL:   AE017223
- RefSeq:   YP_222587.1
- ProteinModelPortal:   Q57AV8
- SMR:   Q57AV8
- MEROPS:   T05.001
- GeneID:   3340537
- GenomeReviews:   AE017223_GR
- KEGG:   bmb:BruAb1_1917
- HOGENOM:   HBG284202
- OMA:   QNRFCAA
- PhylomeDB:   Q57AV8
- ProtClustDB:   PRK05388
- BioCyc:   BABO262698:BRUAB1_1917-MONOMER
- BRENDA:   2.3.1.1
- BRENDA:   2.3.1.35
- GO:   GO:0005737
- HAMAP:   MF_01106
- InterPro:   IPR002813
- InterPro:   IPR016117
- PANTHER:   PTHR23100
- TIGRFAMs:   TIGR00120

Pfam domain/function: PF01960 ArgJ; SSF56266 Pept_S58_DmpA/Arg_biosyn_ArgJ

EC number: =2.3.1.35; =2.3.1.1

Molecular weight: Translated: 43245; Mature: 43114

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASVSPLAPKHYPAMPVIHGVRIATAAAGIKYKGRTDLMLMVFDRPAEAAGVFTRSLCP
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEECCCCCEEEEEECCCCHHHHHHHHHCCC
SAPVDFCRRNLVHGKARAVVVNSGNANAFTGLKGREATQATAEAAAKAIGCATTDIFLAS
CCCHHHHHHHHCCCCEEEEEEECCCCCEECCCCCCCHHHHHHHHHHHHHCCCHHEEEEEE
TGVIGEPLDAGKFSHLLGDMAESATEDFWTEAAKAIMTTDTYPKVATETVLLGQVPVTIN
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHCEEEEECCCEEEE
GIAKGAGMIAPDMATMLSFVVTDAPIKADALQSLLSKGVGSTFNSVTVDSDTSTSDTLML
CCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEEE
FATGTAAERGAPEITDAADKRLADFKKALGRVLKSLALQVVRDGEGARKMVEVEVTGAKS
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCC
AASAKKIALSIANSPLVKTAVAGEDANWGRVVMAVGKAGEPADRDRLAIWFGDIRVAHQG
HHHHHEEEEEECCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCEEEEEEEEEEEEECC
ERDPAYSEDATSAYMEGEDIRIRVDLGIGRGKATVWTCDLTKEYVAINGDYRS
CCCCCCCCCCHHHHCCCCEEEEEEEEECCCCCEEEEEEECCCEEEEECCCCCC
>Mature Secondary Structure 
SASVSPLAPKHYPAMPVIHGVRIATAAAGIKYKGRTDLMLMVFDRPAEAAGVFTRSLCP
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEECCCCCEEEEEECCCCHHHHHHHHHCCC
SAPVDFCRRNLVHGKARAVVVNSGNANAFTGLKGREATQATAEAAAKAIGCATTDIFLAS
CCCHHHHHHHHCCCCEEEEEEECCCCCEECCCCCCCHHHHHHHHHHHHHCCCHHEEEEEE
TGVIGEPLDAGKFSHLLGDMAESATEDFWTEAAKAIMTTDTYPKVATETVLLGQVPVTIN
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHCEEEEECCCEEEE
GIAKGAGMIAPDMATMLSFVVTDAPIKADALQSLLSKGVGSTFNSVTVDSDTSTSDTLML
CCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEEE
FATGTAAERGAPEITDAADKRLADFKKALGRVLKSLALQVVRDGEGARKMVEVEVTGAKS
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCC
AASAKKIALSIANSPLVKTAVAGEDANWGRVVMAVGKAGEPADRDRLAIWFGDIRVAHQG
HHHHHEEEEEECCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCEEEEEEEEEEEEECC
ERDPAYSEDATSAYMEGEDIRIRVDLGIGRGKATVWTCDLTKEYVAINGDYRS
CCCCCCCCCCHHHHCCCCEEEEEEEEECCCCCEEEEEEECCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA