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The map label for this gene is sdhB [H]

Identifier: 23502752

GI number: 23502752

Start: 1836001

End: 1836780

Strand: Reverse

Name: sdhB [H]

Synonym: BR1901

Alternate gene names: 23502752

Gene position: 1836780-1836001 (Counterclockwise)

Preceding gene: 23502753

Following gene: 23502751

Centisome position: 87.14

GC content: 56.92

Gene sequence:

>780_bases
ATGGTTGAACTCGCACTTCCCAAGAATTCCCGTATGCAGGAGGGCAAGACCTGGCCCCGTCCTGATGGCGCCACCCGTGT
CACGGAATTCCGCATCTATCGCTGGTCGCCGGATGACGACGAAAATCCGCGTATCGATACCTATTATGTCGATCGTGACG
ATTGTGGTCCGATGGTTCTGGACGGTCTGCTCTATATCAAGAACAAGATCGACCCGACGCTGACGCTGCGCCGTTCGTGC
CGTGAAGGCATTTGCGGTTCCTGCGCCATGAATATCGATGGCGCGAACACGCTTGCCTGCACCAAGGGTATGGACGACAT
CAAGGGCACCATCAAGGTCTATCCGCTGCCGCATATGCCGGTGGTGAAGGATCTTGTGCCGGACCTCAATAATTTCTACG
CCCAGCACCGTTCCATTGAGCCATGGCTCAAGACGGTTTCGCCGGAGCCGCAGATGGAATGGCTGCAAAGCCATGAGGAC
CGCCAGAAGCTCGATGGTCTTTATGAGTGCATTCTGTGCGCCTGCTGCTCGACCTCATGCCCGAGCTATTGGTGGAACGG
CGACCGTTATCTTGGCCCCGCCGTGCTGCTTCAGGCCTATCGCTGGCTGATCGATTCCAGAGACGAAGCCAAGGGCGAAC
GCCTCGATAACCTTGAGGATCCGTTCCGGCTTTATCGCTGCCATACGATCATGAATTGCGCCCAGACCTGCCCGAAGGGT
CTGAACCCGGCCAAGGCGATTGCCGAAATCAAGAAGATGATGGTCGAACGCCGCGTGTAA

Upstream 100 bases:

>100_bases
TTCGGTTCATCTCGATCCGCTGACGACGGAAGAGGAAGGTGGCATCAGCCTCGCCAAGATTGCGCCGAAGAAGCGCGTTT
ACTGATCAGGGGCAAGAGCA

Downstream 100 bases:

>100_bases
CCACGGCAATCGTTGGTCTTTTTAGTCCCTGTCGCGCCAGAGGCGCTCCACGCCTCTTGTTTGCGTCTCTGTCGGCCTGG
GGGCCTCCGTGCCTCTTGGT

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MVELALPKNSRMQEGKTWPRPDGATRVTEFRIYRWSPDDDENPRIDTYYVDRDDCGPMVLDGLLYIKNKIDPTLTLRRSC
REGICGSCAMNIDGANTLACTKGMDDIKGTIKVYPLPHMPVVKDLVPDLNNFYAQHRSIEPWLKTVSPEPQMEWLQSHED
RQKLDGLYECILCACCSTSCPSYWWNGDRYLGPAVLLQAYRWLIDSRDEAKGERLDNLEDPFRLYRCHTIMNCAQTCPKG
LNPAKAIAEIKKMMVERRV

Sequences:

>Translated_259_residues
MVELALPKNSRMQEGKTWPRPDGATRVTEFRIYRWSPDDDENPRIDTYYVDRDDCGPMVLDGLLYIKNKIDPTLTLRRSC
REGICGSCAMNIDGANTLACTKGMDDIKGTIKVYPLPHMPVVKDLVPDLNNFYAQHRSIEPWLKTVSPEPQMEWLQSHED
RQKLDGLYECILCACCSTSCPSYWWNGDRYLGPAVLLQAYRWLIDSRDEAKGERLDNLEDPFRLYRCHTIMNCAQTCPKG
LNPAKAIAEIKKMMVERRV
>Mature_259_residues
MVELALPKNSRMQEGKTWPRPDGATRVTEFRIYRWSPDDDENPRIDTYYVDRDDCGPMVLDGLLYIKNKIDPTLTLRRSC
REGICGSCAMNIDGANTLACTKGMDDIKGTIKVYPLPHMPVVKDLVPDLNNFYAQHRSIEPWLKTVSPEPQMEWLQSHED
RQKLDGLYECILCACCSTSCPSYWWNGDRYLGPAVLLQAYRWLIDSRDEAKGERLDNLEDPFRLYRCHTIMNCAQTCPKG
LNPAKAIAEIKKMMVERRV

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=236, Percent_Identity=69.4915254237288, Blast_Score=348, Evalue=2e-96,
Organism=Escherichia coli, GI1786943, Length=234, Percent_Identity=52.991452991453, Blast_Score=257, Evalue=6e-70,
Organism=Escherichia coli, GI1790596, Length=224, Percent_Identity=33.0357142857143, Blast_Score=129, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17533915, Length=236, Percent_Identity=61.864406779661, Blast_Score=310, Evalue=5e-85,
Organism=Saccharomyces cerevisiae, GI6322987, Length=233, Percent_Identity=65.2360515021459, Blast_Score=315, Evalue=5e-87,
Organism=Drosophila melanogaster, GI17137106, Length=256, Percent_Identity=62.109375, Blast_Score=343, Evalue=7e-95,
Organism=Drosophila melanogaster, GI24643156, Length=234, Percent_Identity=61.965811965812, Blast_Score=312, Evalue=1e-85,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 29828; Mature: 29828

Theoretical pI: Translated: 6.49; Mature: 6.49

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
8.9 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
8.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVELALPKNSRMQEGKTWPRPDGATRVTEFRIYRWSPDDDENPRIDTYYVDRDDCGPMVL
CEEECCCCCCCHHCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCEEEEEECCCCCCHHHH
DGLLYIKNKIDPTLTLRRSCREGICGSCAMNIDGANTLACTKGMDDIKGTIKVYPLPHMP
HHHHHHHHCCCHHHHHHHHHHCCCCCCEEECCCCCCCEEECCCCHHCCCCEEEEECCCCC
VVKDLVPDLNNFYAQHRSIEPWLKTVSPEPQMEWLQSHEDRQKLDGLYECILCACCSTSC
HHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PSYWWNGDRYLGPAVLLQAYRWLIDSRDEAKGERLDNLEDPFRLYRCHTIMNCAQTCPKG
CCCCCCCCCCCCHHHHHHHHHHHHCCCCHHCCCHHCCCCHHHHHHHHHHHHHHHHHCCCC
LNPAKAIAEIKKMMVERRV
CCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVELALPKNSRMQEGKTWPRPDGATRVTEFRIYRWSPDDDENPRIDTYYVDRDDCGPMVL
CEEECCCCCCCHHCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCEEEEEECCCCCCHHHH
DGLLYIKNKIDPTLTLRRSCREGICGSCAMNIDGANTLACTKGMDDIKGTIKVYPLPHMP
HHHHHHHHCCCHHHHHHHHHHCCCCCCEEECCCCCCCEEECCCCHHCCCCEEEEECCCCC
VVKDLVPDLNNFYAQHRSIEPWLKTVSPEPQMEWLQSHEDRQKLDGLYECILCACCSTSC
HHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PSYWWNGDRYLGPAVLLQAYRWLIDSRDEAKGERLDNLEDPFRLYRCHTIMNCAQTCPKG
CCCCCCCCCCCCHHHHHHHHHHHHCCCCHHCCCHHCCCCHHHHHHHHHHHHHHHHHCCCC
LNPAKAIAEIKKMMVERRV
CCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA