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The map label for this gene is rlmH

Identifier: 23502693

GI number: 23502693

Start: 1772232

End: 1772756

Strand: Reverse

Name: rlmH

Synonym: BR1840

Alternate gene names: 23502693

Gene position: 1772756-1772232 (Counterclockwise)

Preceding gene: 23502694

Following gene: 23502692

Centisome position: 84.1

GC content: 63.05

Gene sequence:

>525_bases
ATGCGTGTGAGTGTTTTTGCCGTGGGCCGGATGAAGTCCGGCCCCGAACGGGAGCTGGTTGAGCGTTATTTCGACCGATT
TGCAAAGGCTGGGCCGCCCTTGGGGCTTGAATTCGCCGGTGTCAGCGAAATTCCTGAAAGCCGGGGCCAGACGGCACAGT
TGCGCAAGGCCGAAGAGGCCCAGCGTATCCATGAGGCGCTTGACAATGCCAAGTCCGGTGGGGCCAAGTCCGGTGGGACC
AGTTCCGGGGGCGCTGCCCTGATCCTGCTTGACGAGCGCGGCAAGACACTTGGTTCGGAAGCTTTTGCGGCCATTGTCGG
ACGTATGCGCGACGACGGCAAGCGCCAGCTTATCGTTGCCATTGGCGGCCCGGACGGCCATGACCCGGCATTGCGGTCGC
GCGCTGATCTTGTTCTGGCGCTGGGGGAGCTCACCTGGCCGCACCAGATTGCCCGTATCCTGATTGCCGAACAGCTTTAC
CGCGCCGCCACCATTCTGGCGGGGCACCCCTATCATCGGTCGTGA

Upstream 100 bases:

>100_bases
AGTCCGTGACTTCTACAATCTCGAGAAGATATGGCTCGATGACGATTTCGGCGACGAACGTGCGCCGGGATTGGTGCATT
GACCGTATATTGAGGGCGTC

Downstream 100 bases:

>100_bases
CGACCTTCATTTCCTTGACAAAGTGCGTAAACCTTAGGATTGCTCCTCGCAACAAAATGCGTCTGACCGTTCCGGCTGTA
TGGTTTTGATTAGTATTATC

Product: rRNA large subunit methyltransferase

Products: NA

Alternate protein names: 23S rRNA m3Psi1915 methyltransferase; rRNA (pseudouridine-N3-)-methyltransferase rlmH

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MRVSVFAVGRMKSGPERELVERYFDRFAKAGPPLGLEFAGVSEIPESRGQTAQLRKAEEAQRIHEALDNAKSGGAKSGGT
SSGGAALILLDERGKTLGSEAFAAIVGRMRDDGKRQLIVAIGGPDGHDPALRSRADLVLALGELTWPHQIARILIAEQLY
RAATILAGHPYHRS

Sequences:

>Translated_174_residues
MRVSVFAVGRMKSGPERELVERYFDRFAKAGPPLGLEFAGVSEIPESRGQTAQLRKAEEAQRIHEALDNAKSGGAKSGGT
SSGGAALILLDERGKTLGSEAFAAIVGRMRDDGKRQLIVAIGGPDGHDPALRSRADLVLALGELTWPHQIARILIAEQLY
RAATILAGHPYHRS
>Mature_174_residues
MRVSVFAVGRMKSGPERELVERYFDRFAKAGPPLGLEFAGVSEIPESRGQTAQLRKAEEAQRIHEALDNAKSGGAKSGGT
SSGGAALILLDERGKTLGSEAFAAIVGRMRDDGKRQLIVAIGGPDGHDPALRSRADLVLALGELTWPHQIARILIAEQLY
RAATILAGHPYHRS

Specific function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA

COG id: COG1576

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase rlmH family

Homologues:

Organism=Escherichia coli, GI1786855, Length=175, Percent_Identity=32, Blast_Score=75, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMH_BRUMB (C0RF89)

Other databases:

- EMBL:   CP001488
- RefSeq:   YP_002733515.1
- ProteinModelPortal:   C0RF89
- SMR:   C0RF89
- GeneID:   7677375
- GenomeReviews:   CP001488_GR
- KEGG:   bmi:BMEA_A1890
- OMA:   ILSGHPY
- ProtClustDB:   PRK00103
- GO:   GO:0005737
- HAMAP:   MF_00658
- InterPro:   IPR003742
- PIRSF:   PIRSF004505

Pfam domain/function: PF02590 SPOUT_MTase

EC number: NA

Molecular weight: Translated: 18650; Mature: 18650

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVSVFAVGRMKSGPERELVERYFDRFAKAGPPLGLEFAGVSEIPESRGQTAQLRKAEEA
CEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCHHCHHHCCCHHHHHHHHHH
QRIHEALDNAKSGGAKSGGTSSGGAALILLDERGKTLGSEAFAAIVGRMRDDGKRQLIVA
HHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEEE
IGGPDGHDPALRSRADLVLALGELTWPHQIARILIAEQLYRAATILAGHPYHRS
ECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRVSVFAVGRMKSGPERELVERYFDRFAKAGPPLGLEFAGVSEIPESRGQTAQLRKAEEA
CEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCHHCHHHCCCHHHHHHHHHH
QRIHEALDNAKSGGAKSGGTSSGGAALILLDERGKTLGSEAFAAIVGRMRDDGKRQLIVA
HHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEEE
IGGPDGHDPALRSRADLVLALGELTWPHQIARILIAEQLYRAATILAGHPYHRS
ECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA