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The map label for this gene is cynT [H]

Identifier: 23502682

GI number: 23502682

Start: 1761486

End: 1762127

Strand: Reverse

Name: cynT [H]

Synonym: BR1829

Alternate gene names: 23502682

Gene position: 1762127-1761486 (Counterclockwise)

Preceding gene: 23502683

Following gene: 23502679

Centisome position: 83.6

GC content: 55.45

Gene sequence:

>642_bases
ATGGCTGATCTTCCAGATTCACTTCTTGCTGGTTACAAAACCTTCATGAGCGAGCATTTCGCGCATGAAACGGCACGCTA
CAGGGACTTGGCTGAAAAAGGGCAATCGCCGGAAACTCTGGTTGTTGCCTGCTGCGATTCCCGCGCTGCGCCGGAAACCA
TCTTCAATGCCGCACCGGGCGAAATCTTTGTCCTTCGCAATGTGGCCAATCTCATTCCGCCCTATGAGCCGGATGGTGAA
TACCACGCGGCTTCGGCGGCTTTGGAATTTGCCGTGCAGAGCCTCAAGGTAAAACATATCGTGGTGATGGGCCACGGGCG
TTGCGGTGGCATCAAGGCGGCGCTCGACACTGAAAGCGCCCCGCTTTCACCGAGCGATTTTATCGGAAAATGGATGAGCC
TCATTTCGCCCGCGGCAGAGGCCATCAGCGGAAATGCGCTCATGACGCAAAGCGAGCGTCATACGGCGCTGGAGCGTATT
TCGATCCGCTATTCGCTGGCTAATCTGCGCACTTTCCCTTGCGTGGATATTCTGGAGAAGAAGGGCAAGCTCACCCTGCA
TGGCGCATGGTTCGATATTTCGACCGGCGAATTGTGGGTGATGGATCACCGGACCGGTGATTTCAAACGCCCTGAACTTT
GA

Upstream 100 bases:

>100_bases
AGAATGCACATGAAACCTGTGTGAAAATTTGTCCGAGAGGATGGGTTCCACAGGGTTCATTTTGATTGATCTTTGAATTC
GATAGGGATATTCAAACGCT

Downstream 100 bases:

>100_bases
TAGAAATATTGTGAATGTACAAGAAAGCCCGGCCGAAGCCGGGCTTTCTTGTATTTCATGCAATTATTTGCCGTCGATGG
CCTTGCCCATGACGGCGATG

Product: carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase 1 [H]

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MADLPDSLLAGYKTFMSEHFAHETARYRDLAEKGQSPETLVVACCDSRAAPETIFNAAPGEIFVLRNVANLIPPYEPDGE
YHAASAALEFAVQSLKVKHIVVMGHGRCGGIKAALDTESAPLSPSDFIGKWMSLISPAAEAISGNALMTQSERHTALERI
SIRYSLANLRTFPCVDILEKKGKLTLHGAWFDISTGELWVMDHRTGDFKRPEL

Sequences:

>Translated_213_residues
MADLPDSLLAGYKTFMSEHFAHETARYRDLAEKGQSPETLVVACCDSRAAPETIFNAAPGEIFVLRNVANLIPPYEPDGE
YHAASAALEFAVQSLKVKHIVVMGHGRCGGIKAALDTESAPLSPSDFIGKWMSLISPAAEAISGNALMTQSERHTALERI
SIRYSLANLRTFPCVDILEKKGKLTLHGAWFDISTGELWVMDHRTGDFKRPEL
>Mature_212_residues
ADLPDSLLAGYKTFMSEHFAHETARYRDLAEKGQSPETLVVACCDSRAAPETIFNAAPGEIFVLRNVANLIPPYEPDGEY
HAASAALEFAVQSLKVKHIVVMGHGRCGGIKAALDTESAPLSPSDFIGKWMSLISPAAEAISGNALMTQSERHTALERIS
IRYSLANLRTFPCVDILEKKGKLTLHGAWFDISTGELWVMDHRTGDFKRPEL

Specific function: Reversible hydration of carbon dioxide. Carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (CynS) diffuses out of the cell faster than it would be hydrated to bicarbonate, so the apparent function of this enzyme is to c

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=201, Percent_Identity=32.3383084577114, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1786318, Length=206, Percent_Identity=28.6407766990291, Blast_Score=75, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI115532990, Length=230, Percent_Identity=25.6521739130435, Blast_Score=73, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI25147564, Length=201, Percent_Identity=27.8606965174129, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6324292, Length=208, Percent_Identity=30.2884615384615, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 23344; Mature: 23213

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLPDSLLAGYKTFMSEHFAHETARYRDLAEKGQSPETLVVACCDSRAAPETIFNAAPG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHCCCCC
EIFVLRNVANLIPPYEPDGEYHAASAALEFAVQSLKVKHIVVMGHGRCGGIKAALDTESA
CEEEEECHHHHCCCCCCCCCHHHHHHHHHHHHHHHCEEEEEEEECCCCCCEEEEECCCCC
PLSPSDFIGKWMSLISPAAEAISGNALMTQSERHTALERISIRYSLANLRTFPCVDILEK
CCCHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHEEEHHHCCCCCHHHHHHC
KGKLTLHGAWFDISTGELWVMDHRTGDFKRPEL
CCCEEEEEEEEEECCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
ADLPDSLLAGYKTFMSEHFAHETARYRDLAEKGQSPETLVVACCDSRAAPETIFNAAPG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHCCCCC
EIFVLRNVANLIPPYEPDGEYHAASAALEFAVQSLKVKHIVVMGHGRCGGIKAALDTESA
CEEEEECHHHHCCCCCCCCCHHHHHHHHHHHHHHHCEEEEEEEECCCCCCEEEEECCCCC
PLSPSDFIGKWMSLISPAAEAISGNALMTQSERHTALERISIRYSLANLRTFPCVDILEK
CCCHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHEEEHHHCCCCCHHHHHHC
KGKLTLHGAWFDISTGELWVMDHRTGDFKRPEL
CCCEEEEEEEEEECCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]