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The map label for this gene is qorA [H]

Identifier: 23502595

GI number: 23502595

Start: 1675685

End: 1676665

Strand: Reverse

Name: qorA [H]

Synonym: BR1738

Alternate gene names: 23502595

Gene position: 1676665-1675685 (Counterclockwise)

Preceding gene: 23502598

Following gene: 23502594

Centisome position: 79.55

GC content: 61.77

Gene sequence:

>981_bases
ATGACCGCTATCGAAATCACCGAGCCCGGCGGCGCCTACATGCTGCGCCCGGCGCAGCGCGCGGTGCCGGAGCCGAAGGA
GGGTGAAATTCTGGTGCGGGTGCGCGCGGCCGGCGTCAACCGACCCGACGTGTTGCAGCGGCAGGGCCAATATGCACCCC
CGCCGGGGGCTTCCGATATTCCGGGGCTGGAAATTGCCGGTGACATCGTCGCCCTTGGGCATGGGGTGAAGCGGTTCAGG
AAGGGCGATCAGGTCGTGGCCCTTTTGGCTGGCGGTGGCTATGCCGAATATGCCGTGGTGCATGAAAGCAATGCGCTGCC
GCTGCCATCGGGGTTTGGCTATATCGAAGCGGCGGCGATCCCGGAAACCTTCTTCACCGTCTGGCATAATGTTTTCGAGC
GCGGGGGGCTTAAGGAGGGAGAGGTTTTTCTGGTTCATGGCGGCTCGTCCGGTATCGGCACGACTGCGATCCAGCTTGCC
AAGGCTTTTGGCGCGACGGTCATCACCACCGCAGGATCGAAGGAAAAATGCGACGCCTGCGTGAAGCTTGGCGCAGACCG
AGCCATCAATTATCACGAGGAGGATTTTGTCGCGGTTGTGAAAGAGATGACCGGCGGCAAGGGCGTGGATGTGATTCTGG
ACATGGTGGGTGGCGATTATGTCGAGCGCAATTACAAGGCTGCCGCCGAGGATGGGCGCATCGTGCAGATTGCTTTCCTG
AACGGGGCCAAGGCAACGGCCAATTTCGCGATTCTGATGACCAAGCGGCTGACCCATACCGGCTCCACGCTGCGCCCGCG
CCCGGTGGCGTTCAAGGCGGGTATCGCCAGAGAACTGGAGGCCAAGGTTTGGCCGCTTCTGGCGCAGCGCCGTGTCGCGC
CTGTGATGGATATGATTTTTTCGCTGAAAGATGCCTGGCGGGCGCATGAGCGCATGGAGGAGGGGCGCCATATCGGCAAG
ATCGTGCTGGACATAGCGTAG

Upstream 100 bases:

>100_bases
TGGGCATTTTTGCGGCCTTTATTGGACGGGCCGATGTCCATATAAAAATCAAGAAATATGAACGGAGTTTTTGACAATGA
TGGCCGAATTGCCCTCCCTG

Downstream 100 bases:

>100_bases
AATATCGACATAGAGCCATTCTTGCTCTGGCGACAAAAAACCTATATACAAGCCATGATTTCCCGGAAATTGTGGTTTTG
CCCACGTCCCGCGCCACCGG

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MTAIEITEPGGAYMLRPAQRAVPEPKEGEILVRVRAAGVNRPDVLQRQGQYAPPPGASDIPGLEIAGDIVALGHGVKRFR
KGDQVVALLAGGGYAEYAVVHESNALPLPSGFGYIEAAAIPETFFTVWHNVFERGGLKEGEVFLVHGGSSGIGTTAIQLA
KAFGATVITTAGSKEKCDACVKLGADRAINYHEEDFVAVVKEMTGGKGVDVILDMVGGDYVERNYKAAAEDGRIVQIAFL
NGAKATANFAILMTKRLTHTGSTLRPRPVAFKAGIARELEAKVWPLLAQRRVAPVMDMIFSLKDAWRAHERMEEGRHIGK
IVLDIA

Sequences:

>Translated_326_residues
MTAIEITEPGGAYMLRPAQRAVPEPKEGEILVRVRAAGVNRPDVLQRQGQYAPPPGASDIPGLEIAGDIVALGHGVKRFR
KGDQVVALLAGGGYAEYAVVHESNALPLPSGFGYIEAAAIPETFFTVWHNVFERGGLKEGEVFLVHGGSSGIGTTAIQLA
KAFGATVITTAGSKEKCDACVKLGADRAINYHEEDFVAVVKEMTGGKGVDVILDMVGGDYVERNYKAAAEDGRIVQIAFL
NGAKATANFAILMTKRLTHTGSTLRPRPVAFKAGIARELEAKVWPLLAQRRVAPVMDMIFSLKDAWRAHERMEEGRHIGK
IVLDIA
>Mature_325_residues
TAIEITEPGGAYMLRPAQRAVPEPKEGEILVRVRAAGVNRPDVLQRQGQYAPPPGASDIPGLEIAGDIVALGHGVKRFRK
GDQVVALLAGGGYAEYAVVHESNALPLPSGFGYIEAAAIPETFFTVWHNVFERGGLKEGEVFLVHGGSSGIGTTAIQLAK
AFGATVITTAGSKEKCDACVKLGADRAINYHEEDFVAVVKEMTGGKGVDVILDMVGGDYVERNYKAAAEDGRIVQIAFLN
GAKATANFAILMTKRLTHTGSTLRPRPVAFKAGIARELEAKVWPLLAQRRVAPVMDMIFSLKDAWRAHERMEEGRHIGKI
VLDIA

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=330, Percent_Identity=40, Blast_Score=240, Evalue=1e-63,
Organism=Homo sapiens, GI22538444, Length=330, Percent_Identity=40, Blast_Score=240, Evalue=1e-63,
Organism=Homo sapiens, GI194239674, Length=331, Percent_Identity=30.5135951661631, Blast_Score=144, Evalue=9e-35,
Organism=Homo sapiens, GI13236495, Length=331, Percent_Identity=30.5135951661631, Blast_Score=144, Evalue=9e-35,
Organism=Homo sapiens, GI24308257, Length=347, Percent_Identity=29.971181556196, Blast_Score=138, Evalue=8e-33,
Organism=Homo sapiens, GI194239676, Length=210, Percent_Identity=34.7619047619048, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI18379349, Length=309, Percent_Identity=26.2135922330097, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI28557745, Length=319, Percent_Identity=33.8557993730408, Blast_Score=121, Evalue=7e-28,
Organism=Homo sapiens, GI41872631, Length=320, Percent_Identity=28.125, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI47519420, Length=332, Percent_Identity=27.4096385542169, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI197927207, Length=200, Percent_Identity=27, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1790485, Length=319, Percent_Identity=35.423197492163, Blast_Score=147, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17507255, Length=331, Percent_Identity=27.4924471299094, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI212642053, Length=316, Percent_Identity=26.8987341772152, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17536829, Length=200, Percent_Identity=26.5, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71987554, Length=184, Percent_Identity=30.9782608695652, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=333, Percent_Identity=30.03003003003, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6323961, Length=334, Percent_Identity=25.1497005988024, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324486, Length=334, Percent_Identity=24.5508982035928, Blast_Score=72, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6319621, Length=275, Percent_Identity=26.9090909090909, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24581345, Length=300, Percent_Identity=27.3333333333333, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI221330659, Length=300, Percent_Identity=27.3333333333333, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI19920632, Length=300, Percent_Identity=27.3333333333333, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI45550423, Length=156, Percent_Identity=27.5641025641026, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34953; Mature: 34821

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAIEITEPGGAYMLRPAQRAVPEPKEGEILVRVRAAGVNRPDVLQRQGQYAPPPGASDI
CCEEEEECCCCCEEECCHHHCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCCCCCCCC
PGLEIAGDIVALGHGVKRFRKGDQVVALLAGGGYAEYAVVHESNALPLPSGFGYIEAAAI
CCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCCCEEEHHC
PETFFTVWHNVFERGGLKEGEVFLVHGGSSGIGTTAIQLAKAFGATVITTAGSKEKCDAC
HHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCEEEEECCCHHHHHHH
VKLGADRAINYHEEDFVAVVKEMTGGKGVDVILDMVGGDYVERNYKAAAEDGRIVQIAFL
HHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHEEHHCCHHHHCCCHHHCCCCCEEEEEEE
NGAKATANFAILMTKRLTHTGSTLRPRPVAFKAGIARELEAKVWPLLAQRRVAPVMDMIF
CCCCCCCCEEEEEEEHHHCCCCCCCCCCEEEHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLKDAWRAHERMEEGRHIGKIVLDIA
HHHHHHHHHHHHHCCCCEEEEEEEEC
>Mature Secondary Structure 
TAIEITEPGGAYMLRPAQRAVPEPKEGEILVRVRAAGVNRPDVLQRQGQYAPPPGASDI
CEEEEECCCCCEEECCHHHCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCCCCCCCC
PGLEIAGDIVALGHGVKRFRKGDQVVALLAGGGYAEYAVVHESNALPLPSGFGYIEAAAI
CCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCCCEEEHHC
PETFFTVWHNVFERGGLKEGEVFLVHGGSSGIGTTAIQLAKAFGATVITTAGSKEKCDAC
HHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCEEEEECCCHHHHHHH
VKLGADRAINYHEEDFVAVVKEMTGGKGVDVILDMVGGDYVERNYKAAAEDGRIVQIAFL
HHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHEEHHCCHHHHCCCHHHCCCCCEEEEEEE
NGAKATANFAILMTKRLTHTGSTLRPRPVAFKAGIARELEAKVWPLLAQRRVAPVMDMIF
CCCCCCCCEEEEEEEHHHCCCCCCCCCCEEEHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLKDAWRAHERMEEGRHIGKIVLDIA
HHHHHHHHHHHHHCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]