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The map label for this gene is ruvB

Identifier: 23502560

GI number: 23502560

Start: 1645641

End: 1646681

Strand: Reverse

Name: ruvB

Synonym: BR1702

Alternate gene names: 23502560

Gene position: 1646681-1645641 (Counterclockwise)

Preceding gene: 23502561

Following gene: 23502559

Centisome position: 78.12

GC content: 61.67

Gene sequence:

>1041_bases
ATGAGCGACCGTAACCCCCTGATCGATGCCGACCGGCGCGCAGACGAAGACAATACGCTGCGCCCGCAGACGCTTGACGA
TTTTGTGGGCCAAGCGGCGGCGCGCGCCAATCTGAAAGTGTTTATTGAAGCCGCCAAGGTGCGTGGCGAGGCGCTGGATC
ATGTGCTTTTCGTCGGCCCGCCCGGCCTCGGCAAGACGACGCTGGCGCAGATCATGGCGAAAGAACTTGGCGTCAATTTC
CGCTCCACATCCGGCCCGGTCATCGCCAAGGCGGGCGATCTCGCCGCGCTGCTTACCAATCTGGAAGAGCGCGACGTGTT
GTTCATCGATGAAATCCATCGCCTGAGCCCCGCGGTGGAAGAAATTCTCTATCCGGCCATGGAGGATTTTCAGCTCGATC
TCATCATCGGCGAGGGGCCTGCCGCGCGTTCGGTCAAGATCGACCTCGCCAAGTTTACGCTTGTTGCCGCCACGACGCGC
CTTGGCCTGCTCACCACGCCCCTGCGCGACCGGTTCGGCATTCCGGTGCGGCTCAATTTCTATACGGTCGAAGAGCTGGA
ATATATTGTGCGGCGCGGCGCGCGCATCATGCAGATGGGAATCTCGTCTGACGGCGCGCGGGAAGTTGCCCGCCGTTCGC
GCGGCACGCCGCGTATTGCCGGGCGGCTTTTGCGGCGCGTGCGCGATTTCGCGCTGGTCGCGGGCGCGGATATCATAGAC
CGCAGAATAGCCGATGAGGCGCTGTCGCGGCTTGAGGTGGACAATCGCGGCCTCGACCAGCTTGACCGGCGCTATCTCAA
TATTATTGCGCGCAATTTTGGCGGTGGGCCGGTCGGGATCGAAACCATTGCGGCGGGCTTGTCCGAGCCGCGCGATGCGA
TTGAAGACATTATCGAACCCTATCTGATCCAGCAGGGTTTCCTGCAACGCACGCCGCGCGGGCGCGTGCTGACTGCCGTT
GCGTGGCAACATCTGGGATTACCTGCGCCTGCTGAAATCATCCAGCAGTCGCAATATGGCCTCTTCATGGAAGACGAATG
A

Upstream 100 bases:

>100_bases
GGCGAGGGCGCCGATTCGGCCAAGCTGATACGGCTCGGTTTGAAGGAACTCTCGCAGTGATTTACTTGTCTGAACATGAG
CTTCATGCGAGGAGAGGGGC

Downstream 100 bases:

>100_bases
CCGACAAGCAGCAACAGGCCGTATCCGGCGAACTCAAAGACGGCGCGCATCTATTATGCCGATACGGATTTTTCCGGCTT
TGTTTATCACGGGCGCTATC

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MSDRNPLIDADRRADEDNTLRPQTLDDFVGQAAARANLKVFIEAAKVRGEALDHVLFVGPPGLGKTTLAQIMAKELGVNF
RSTSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLSPAVEEILYPAMEDFQLDLIIGEGPAARSVKIDLAKFTLVAATTR
LGLLTTPLRDRFGIPVRLNFYTVEELEYIVRRGARIMQMGISSDGAREVARRSRGTPRIAGRLLRRVRDFALVAGADIID
RRIADEALSRLEVDNRGLDQLDRRYLNIIARNFGGGPVGIETIAAGLSEPRDAIEDIIEPYLIQQGFLQRTPRGRVLTAV
AWQHLGLPAPAEIIQQSQYGLFMEDE

Sequences:

>Translated_346_residues
MSDRNPLIDADRRADEDNTLRPQTLDDFVGQAAARANLKVFIEAAKVRGEALDHVLFVGPPGLGKTTLAQIMAKELGVNF
RSTSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLSPAVEEILYPAMEDFQLDLIIGEGPAARSVKIDLAKFTLVAATTR
LGLLTTPLRDRFGIPVRLNFYTVEELEYIVRRGARIMQMGISSDGAREVARRSRGTPRIAGRLLRRVRDFALVAGADIID
RRIADEALSRLEVDNRGLDQLDRRYLNIIARNFGGGPVGIETIAAGLSEPRDAIEDIIEPYLIQQGFLQRTPRGRVLTAV
AWQHLGLPAPAEIIQQSQYGLFMEDE
>Mature_345_residues
SDRNPLIDADRRADEDNTLRPQTLDDFVGQAAARANLKVFIEAAKVRGEALDHVLFVGPPGLGKTTLAQIMAKELGVNFR
STSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLSPAVEEILYPAMEDFQLDLIIGEGPAARSVKIDLAKFTLVAATTRL
GLLTTPLRDRFGIPVRLNFYTVEELEYIVRRGARIMQMGISSDGAREVARRSRGTPRIAGRLLRRVRDFALVAGADIIDR
RIADEALSRLEVDNRGLDQLDRRYLNIIARNFGGGPVGIETIAAGLSEPRDAIEDIIEPYLIQQGFLQRTPRGRVLTAVA
WQHLGLPAPAEIIQQSQYGLFMEDE

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=314, Percent_Identity=64.0127388535032, Blast_Score=410, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_BRUA1 (B2S7D9)

Other databases:

- EMBL:   CP000887
- RefSeq:   YP_001935560.1
- ProteinModelPortal:   B2S7D9
- SMR:   B2S7D9
- GeneID:   6327550
- GenomeReviews:   CP000887_GR
- KEGG:   bmc:BAbS19_I16020
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- ProtClustDB:   PRK00080
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR000641
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00819
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 38241; Mature: 38110

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDRNPLIDADRRADEDNTLRPQTLDDFVGQAAARANLKVFIEAAKVRGEALDHVLFVGP
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHEEEEHHHHHHHHHCEEEEECC
PGLGKTTLAQIMAKELGVNFRSTSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLSPAVE
CCCCHHHHHHHHHHHHCCCEECCCCCEEECCCHHHHHHHCCCCCCEEHHHHHHHHHHHHH
EILYPAMEDFQLDLIIGEGPAARSVKIDLAKFTLVAATTRLGLLTTPLRDRFGIPVRLNF
HHHHHHHHCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEE
YTVEELEYIVRRGARIMQMGISSDGAREVARRSRGTPRIAGRLLRRVRDFALVAGADIID
EEHHHHHHHHHCCCCEEHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHH
RRIADEALSRLEVDNRGLDQLDRRYLNIIARNFGGGPVGIETIAAGLSEPRDAIEDIIEP
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHH
YLIQQGFLQRTPRGRVLTAVAWQHLGLPAPAEIIQQSQYGLFMEDE
HHHHHHHHHCCCCCCEEHHHHHHHCCCCCCHHHHHHHCCCCEEECC
>Mature Secondary Structure 
SDRNPLIDADRRADEDNTLRPQTLDDFVGQAAARANLKVFIEAAKVRGEALDHVLFVGP
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHEEEEHHHHHHHHHCEEEEECC
PGLGKTTLAQIMAKELGVNFRSTSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLSPAVE
CCCCHHHHHHHHHHHHCCCEECCCCCEEECCCHHHHHHHCCCCCCEEHHHHHHHHHHHHH
EILYPAMEDFQLDLIIGEGPAARSVKIDLAKFTLVAATTRLGLLTTPLRDRFGIPVRLNF
HHHHHHHHCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEE
YTVEELEYIVRRGARIMQMGISSDGAREVARRSRGTPRIAGRLLRRVRDFALVAGADIID
EEHHHHHHHHHCCCCEEHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHH
RRIADEALSRLEVDNRGLDQLDRRYLNIIARNFGGGPVGIETIAAGLSEPRDAIEDIIEP
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHH
YLIQQGFLQRTPRGRVLTAVAWQHLGLPAPAEIIQQSQYGLFMEDE
HHHHHHHHHCCCCCCEEHHHHHHHCCCCCCHHHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA