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The map label for this gene is mraY

Identifier: 23502305

GI number: 23502305

Start: 1391966

End: 1393048

Strand: Reverse

Name: mraY

Synonym: BR1434

Alternate gene names: 23502305

Gene position: 1393048-1391966 (Counterclockwise)

Preceding gene: 23502306

Following gene: 23502304

Centisome position: 66.09

GC content: 57.25

Gene sequence:

>1083_bases
ATGCTGATGTTTCTCACCCATTTCGCCGAACATGTGACACCGTTCAATGTGTTCCGCTACATTACCTTCCGCACCGGCGG
CGCGATGATTACATCGGCGTTGATCGTGTTCCTGTTCGGCCCCACGATCATCAATTCGCTGAGGGTGCGCCAGGGCAAGG
GACAGCCTATCCGCGCCGACGGGCCGCAGACCCATTTCAAGAAGGCCGGTACGCCGACCATGGGCGGCCTGATGATTATG
ACCGGCATTCTGGCGTCATGCCTGCTATGGGCAAACCTCGCCAGTGTCTATGTCTGGGTCGTGCTGATGGTGTCGGTCGG
CTTTGGCGCCATCGGTTTTTACGACGACTATCTGAAGGTGACGAAACAATCCGACAAAGGCTTTTCCGGCAAGGCGCGCC
TCGGCATTGAATTCCTGATCGCAGCTATTGCCGCTTTCACCATCATGCGGGCCGGGCAGGAGCCGTTCTCATCCTCGCTG
ACCTTTCCCTTCGTCAAGCAGCTCGTCATCAATCTGAGCTGGTTCTTCATTCCTTTCGCAGCCTTCGTCATGGTTGGCGC
GGGCAATGCGGTGAACCTTACCGATGGCCTCGACGGCCTTGCCATCGTGCCGGTGATGGTGGCTGCCGCTTCGTTCGGCT
TCATCGCCTATCTCTCCGGTAATGCGATCTTTGCCGATTATCTGCAAATCCATTTCGTGCCGGGCACGGGTGAGCTTGCG
GTGGTGCTTGGGGCGGTCATCGGCGCCGGTCTCGGCTTTCTCTGGTTCAATGCGCCGCCCGCCGCAATCTTCATGGGCGA
TACAGGTTCGCTGGCTCTGGGCGGTATGCTCGGTACGGTCGCTGTTGCTACCAAGCACGAAATCGTCCTTGCCATTATTG
GCGGTCTGTTTGTCATGGAAGCCCTTTCTGTCATTATTCAGGTCGGGTTCTTCAAGATGACGGGCCGGCGCGTGTTTCTC
ATGGCCCCCATCCACCACCATTTTGAAAAGAAGGGCTGGACCGAGAGCCAGGTCGTGATCCGGTTCTGGATCGTCGCGAT
CATCCTCGCAATGATCGGCCTTTCCACATTGAAACTCAGATAA

Upstream 100 bases:

>100_bases
CCAACAGGACCGGCTTCTCCAAAATCGTCAAGGCGCTGATTGCCCAGTTTCCGCCCGTAGAAGCGGCGGAATAGGCGATT
ATTGAGGGATTGTTTTTCAC

Downstream 100 bases:

>100_bases
CAGGCGAACAAAATGATCCCGATCACCGCCCTCAAGGATAAAACTGTCGCCCTTTTCGGACTGGGCGGGTCGGGCATTGC
GACTGCAAAGGCCATTGTGG

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MLMFLTHFAEHVTPFNVFRYITFRTGGAMITSALIVFLFGPTIINSLRVRQGKGQPIRADGPQTHFKKAGTPTMGGLMIM
TGILASCLLWANLASVYVWVVLMVSVGFGAIGFYDDYLKVTKQSDKGFSGKARLGIEFLIAAIAAFTIMRAGQEPFSSSL
TFPFVKQLVINLSWFFIPFAAFVMVGAGNAVNLTDGLDGLAIVPVMVAAASFGFIAYLSGNAIFADYLQIHFVPGTGELA
VVLGAVIGAGLGFLWFNAPPAAIFMGDTGSLALGGMLGTVAVATKHEIVLAIIGGLFVMEALSVIIQVGFFKMTGRRVFL
MAPIHHHFEKKGWTESQVVIRFWIVAIILAMIGLSTLKLR

Sequences:

>Translated_360_residues
MLMFLTHFAEHVTPFNVFRYITFRTGGAMITSALIVFLFGPTIINSLRVRQGKGQPIRADGPQTHFKKAGTPTMGGLMIM
TGILASCLLWANLASVYVWVVLMVSVGFGAIGFYDDYLKVTKQSDKGFSGKARLGIEFLIAAIAAFTIMRAGQEPFSSSL
TFPFVKQLVINLSWFFIPFAAFVMVGAGNAVNLTDGLDGLAIVPVMVAAASFGFIAYLSGNAIFADYLQIHFVPGTGELA
VVLGAVIGAGLGFLWFNAPPAAIFMGDTGSLALGGMLGTVAVATKHEIVLAIIGGLFVMEALSVIIQVGFFKMTGRRVFL
MAPIHHHFEKKGWTESQVVIRFWIVAIILAMIGLSTLKLR
>Mature_360_residues
MLMFLTHFAEHVTPFNVFRYITFRTGGAMITSALIVFLFGPTIINSLRVRQGKGQPIRADGPQTHFKKAGTPTMGGLMIM
TGILASCLLWANLASVYVWVVLMVSVGFGAIGFYDDYLKVTKQSDKGFSGKARLGIEFLIAAIAAFTIMRAGQEPFSSSL
TFPFVKQLVINLSWFFIPFAAFVMVGAGNAVNLTDGLDGLAIVPVMVAAASFGFIAYLSGNAIFADYLQIHFVPGTGELA
VVLGAVIGAGLGFLWFNAPPAAIFMGDTGSLALGGMLGTVAVATKHEIVLAIIGGLFVMEALSVIIQVGFFKMTGRRVFL
MAPIHHHFEKKGWTESQVVIRFWIVAIILAMIGLSTLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=361, Percent_Identity=50.6925207756233, Blast_Score=347, Evalue=6e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_BRUA1 (B2S6Q7)

Other databases:

- EMBL:   CP000887
- RefSeq:   YP_001935328.1
- GeneID:   6327305
- GenomeReviews:   CP000887_GR
- KEGG:   bmc:BAbS19_I13590
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4

EC number: =2.7.8.13

Molecular weight: Translated: 38746; Mature: 38746

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe375c74)-; HASH(0xeccaac8)-; HASH(0xed6f1e0)-; HASH(0xed6eff4)-; HASH(0xeccac48)-; HASH(0xed92db0)-; HASH(0xed6f090)-; HASH(0xed90b58)-; HASH(0xeccaa44)-; HASH(0xed92b4c)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMFLTHFAEHVTPFNVFRYITFRTGGAMITSALIVFLFGPTIINSLRVRQGKGQPIRAD
CEEEHHHHHHHCCHHHHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GPQTHFKKAGTPTMGGLMIMTGILASCLLWANLASVYVWVVLMVSVGFGAIGFYDDYLKV
CCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
TKQSDKGFSGKARLGIEFLIAAIAAFTIMRAGQEPFSSSLTFPFVKQLVINLSWFFIPFA
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
AFVMVGAGNAVNLTDGLDGLAIVPVMVAAASFGFIAYLSGNAIFADYLQIHFVPGTGELA
HHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHCEEEEEECCEEEEEEEEEEEECCCCHHH
VVLGAVIGAGLGFLWFNAPPAAIFMGDTGSLALGGMLGTVAVATKHEIVLAIIGGLFVME
HHHHHHHHCCHHEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALSVIIQVGFFKMTGRRVFLMAPIHHHFEKKGWTESQVVIRFWIVAIILAMIGLSTLKLR
HHHHHHHHHHEEECCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHCCH
>Mature Secondary Structure
MLMFLTHFAEHVTPFNVFRYITFRTGGAMITSALIVFLFGPTIINSLRVRQGKGQPIRAD
CEEEHHHHHHHCCHHHHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GPQTHFKKAGTPTMGGLMIMTGILASCLLWANLASVYVWVVLMVSVGFGAIGFYDDYLKV
CCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
TKQSDKGFSGKARLGIEFLIAAIAAFTIMRAGQEPFSSSLTFPFVKQLVINLSWFFIPFA
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
AFVMVGAGNAVNLTDGLDGLAIVPVMVAAASFGFIAYLSGNAIFADYLQIHFVPGTGELA
HHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHCEEEEEECCEEEEEEEEEEEECCCCHHH
VVLGAVIGAGLGFLWFNAPPAAIFMGDTGSLALGGMLGTVAVATKHEIVLAIIGGLFVME
HHHHHHHHCCHHEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALSVIIQVGFFKMTGRRVFLMAPIHHHFEKKGWTESQVVIRFWIVAIILAMIGLSTLKLR
HHHHHHHHHHEEECCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA