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The map label for this gene is catB2 [H]

Identifier: 23502286

GI number: 23502286

Start: 1368852

End: 1369541

Strand: Reverse

Name: catB2 [H]

Synonym: BR1415

Alternate gene names: 23502286

Gene position: 1369541-1368852 (Counterclockwise)

Preceding gene: 23502290

Following gene: 23502285

Centisome position: 64.98

GC content: 56.96

Gene sequence:

>690_bases
ATGATGAACCGATACAGGACTGCCGGGCAATATGCAAAAATTTCAGAAAGCTATGAAATGACGCAGGGCGACGACCTCCG
TTTCCAGAACAGCGAGCCGCATATTCATTCGACCGCGCAGCTCAAATCCGTCAAGCTGGGGCGCTATGCCGATATCGGGG
AACGGGTGATCCTGCGTGAAGTAACGGTGGGTGATTTCACCTATTTCGAGCGCAATGGCGAGGGGATTTATGCCGAAATC
GGCAAGTTCTGCTCCATTGCCGCCAATGTGCGGATCAATGCGCTTGAACATCCGATGGAGCGGCTCACCACGCATAAGGT
GAGCTACCGGCCCAACGAATATTTCCGCTATCTTGGCGTTGATGGCGATTTTCGCGCCAGACGGCAGGCAAGGCGGGTCG
TGATCGGCAATGATGTGTGGATCGGCCATGGCGCGGTTATCACGCCGGGCGTGGTGATTGGCCATGGTGCGGTGATCGGG
GCCAATGCGGTGGTGACAAGGGATGTCGCACCCTATTTAGTGGTGGGCGGCGTTCCGGCGCGGCTTATCCGCAAACGGTT
CAGCGATGCGGTGATCGCGCGCCTGCTTGCGCTTTCCTGGTGGGACTGGCCTGTGGAAAAGCTCTATGAGGCTGTTCCCG
ATATTCAGGCGCTTGAGATCGAGGCGTTTTTGGAAAAGTGGGGCGGATGA

Upstream 100 bases:

>100_bases
AGCCTTGAATTTCACTTAACAATATCACTTCATATATGGGCAAAAGCCGGAAGTATCACTGATCTGCGGCAAGGAAACGC
ATATTCAGGCGCACCGCGCT

Downstream 100 bases:

>100_bases
AATCCACACTTGCAAAGCCAGGATTACCTGCCCATTTTCGCAATCGATAATGCTGGAGATAAATATGGTCAGATTGAAGC
ATTTTGCCGGATTGCTGCTT

Product: antibiotic acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MMNRYRTAGQYAKISESYEMTQGDDLRFQNSEPHIHSTAQLKSVKLGRYADIGERVILREVTVGDFTYFERNGEGIYAEI
GKFCSIAANVRINALEHPMERLTTHKVSYRPNEYFRYLGVDGDFRARRQARRVVIGNDVWIGHGAVITPGVVIGHGAVIG
ANAVVTRDVAPYLVVGGVPARLIRKRFSDAVIARLLALSWWDWPVEKLYEAVPDIQALEIEAFLEKWGG

Sequences:

>Translated_229_residues
MMNRYRTAGQYAKISESYEMTQGDDLRFQNSEPHIHSTAQLKSVKLGRYADIGERVILREVTVGDFTYFERNGEGIYAEI
GKFCSIAANVRINALEHPMERLTTHKVSYRPNEYFRYLGVDGDFRARRQARRVVIGNDVWIGHGAVITPGVVIGHGAVIG
ANAVVTRDVAPYLVVGGVPARLIRKRFSDAVIARLLALSWWDWPVEKLYEAVPDIQALEIEAFLEKWGG
>Mature_229_residues
MMNRYRTAGQYAKISESYEMTQGDDLRFQNSEPHIHSTAQLKSVKLGRYADIGERVILREVTVGDFTYFERNGEGIYAEI
GKFCSIAANVRINALEHPMERLTTHKVSYRPNEYFRYLGVDGDFRARRQARRVVIGNDVWIGHGAVITPGVVIGHGAVIG
ANAVVTRDVAPYLVVGGVPARLIRKRFSDAVIARLLALSWWDWPVEKLYEAVPDIQALEIEAFLEKWGG

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786537, Length=199, Percent_Identity=26.6331658291457, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1786664, Length=106, Percent_Identity=37.7358490566038, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 25825; Mature: 25825

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNRYRTAGQYAKISESYEMTQGDDLRFQNSEPHIHSTAQLKSVKLGRYADIGERVILRE
CCCCCCCCCCHHHHHCCCCCCCCCCCEECCCCCCCCCHHHHHHCCCCCCCCCCCEEEEEE
VTVGDFTYFERNGEGIYAEIGKFCSIAANVRINALEHPMERLTTHKVSYRPNEYFRYLGV
EEECCEEEEEECCCCHHHHHHHHHEECCCEEEEHHHHHHHHHHHHCCCCCCCHHEEEECC
DGDFRARRQARRVVIGNDVWIGHGAVITPGVVIGHGAVIGANAVVTRDVAPYLVVGGVPA
CCCHHHHHHHCEEEECCEEEECCCCEECCCEEEECCEEECCCEEEECCCCCEEEECCCHH
RLIRKRFSDAVIARLLALSWWDWPVEKLYEAVPDIQALEIEAFLEKWGG
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEHHHHHHHHHHCC
>Mature Secondary Structure
MMNRYRTAGQYAKISESYEMTQGDDLRFQNSEPHIHSTAQLKSVKLGRYADIGERVILRE
CCCCCCCCCCHHHHHCCCCCCCCCCCEECCCCCCCCCHHHHHHCCCCCCCCCCCEEEEEE
VTVGDFTYFERNGEGIYAEIGKFCSIAANVRINALEHPMERLTTHKVSYRPNEYFRYLGV
EEECCEEEEEECCCCHHHHHHHHHEECCCEEEEHHHHHHHHHHHHCCCCCCCHHEEEECC
DGDFRARRQARRVVIGNDVWIGHGAVITPGVVIGHGAVIGANAVVTRDVAPYLVVGGVPA
CCCHHHHHHHCEEEECCEEEECCCCEECCCEEEECCEEECCCEEEECCCCCEEEECCCHH
RLIRKRFSDAVIARLLALSWWDWPVEKLYEAVPDIQALEIEAFLEKWGG
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1314803 [H]