Click here to switch to the map view.

The map label for this gene is kup [H]

Identifier: 23502254

GI number: 23502254

Start: 1337362

End: 1339317

Strand: Reverse

Name: kup [H]

Synonym: BR1383

Alternate gene names: 23502254

Gene position: 1339317-1337362 (Counterclockwise)

Preceding gene: 23502255

Following gene: 23502252

Centisome position: 63.54

GC content: 58.13

Gene sequence:

>1956_bases
ATGAGCGGCGAGCTAAATGGCAATGACACATCGGCGCAGGCCGCTGTGTCGGCCGGTAGTGTCCTTGAAGGTGCTGCGTT
TGCAGATGAAGGCGAGCAGCATAATGAAAGCATGAAAACGCTGGTGCTGGGTGCGCTTGGCGTCGTCTATGGCGATATCG
GCACCAGCCCGATATATGCTTTCCGCGAAGCTCTTCATGCGGCGGCAACGAATGGAATCCTGGCCCGCAGCGATATTCTC
GGCGTCGTTTCGCTCATCTTCTGGGCGCTGACGCTGGTGGTGACGGTCAAATATGTCCTGTTCGTGCTGCGCGCCGACAA
TAACGGCGAAGGCGGCATTCTCTCGCTCATGGCGCTGGTGCGCGGTGCTCTCAAAGGCAGGCCCGACCTTATCCTCGGCG
TCGGCATTTGCGGTGCGGCACTGTTTTTTGGCGATGCGGTCATCACGCCGGCCATTTCAGTGCTTTCCGCTATGGAAGGT
CTGGAGATTGTCGCGCCCAACCTGACGCCTTTCGTCGTGCCGGCGACGGTCGTCATACTGGTGACGCTGTTTTCCGTTCA
GAAACTGGGAACGGGCAGGGTCGCGATCGTGTTCGGGCCGATCATGGCGCTATGGTTCGTGGCGCTCGGAGCATCCGGGC
TTTGGCATATTTTCGATGACCCGACCGTCATGGCCGCGCTCAATCCCTATTATGCCGTGCGGTTTCTGACAGTCAGTCCG
GCGGTTGCTTTCGTTACCGTCGGTGCTGTTTTCCTCGCCATGACCGGTGCGGAGGCGCTTTATGCCGATCTCGGCCATTT
CGGGCGCAAGCCTATCGTGCGCGCATGGCTGTGGATCGTCTTCCCCTGCCTGCTTCTCAATTATTTCGGGCAGGCGGCTT
TCATTCTCTCGCATGGCGAAGCAGCGGCGCTTCCCTTCTTCCAGATGATACCGAGTTTTGCGCTGTGGCCCATGGTGTTG
CTGGCCACGGCCGCTACCGTTATCGCCAGCCAGGCGGTCATTACCGGCGCCTATTCAGTGGCGCGGCAGGCGGTGCAGCT
CAATATTCTGCCGCGCCTTGAAATCCAGCACACATCCGAGAAATTGCACGGGCAGATCTACATTCCGCGCGTCAACCTGC
TTTTGGGGCTTGCGGTGGTCATTCTGGTGCTGGGCTTTGAAAAATCCAGCAATCTGGCGGCAGCCTATGGCATTGCCGTT
ACCGGCAATATGCTGGTTACGACCGTGCTCCTTTATATCGTGATGACGCGTATCTGGAACTGGCGCGTAAGCCGCGCGCT
GCCGATCATCCTCGGCTTCCTTGTCATCGATATGCTGTTCTTCAGCGCCAATATCATCAAGGTGCATGAGGGCGGCTGGG
CATCCATCGGCATTGCGACTGTGCTGGTTCTTATCATGTGGACATGGGTACGTGGCACGCGCCATCTCTTCCAGAAGACC
CGCAAGGCGGAAGTGCCGCTCGATCTTATCGTCGAGCAGATGGCCAAGCGCCCGCCAACCATCGTGCCGGGAACGGCCGT
CTTCCTGACCGGCGATCCAAAAAGCGCCCCGACTGCGCTGATGCACAGCCTGAAACATTATAAGGTTCTGCACGAGAACA
ATGTCATCTTGACGGTTGTTACCGCATCGAAGCCTTGGGTTGCTTCAGCCGATCGCGCGCGCGTGTCCCAGTATAACGAG
CGCTTCATGCTGGTGACTTTGACCTTTGGCTATATGCAGCAGCCGAATATTCTGCGCGCGCTCGGCCTTTGCCGCAGGCT
TGGGTGGAAGTTCGACATCATGACGACATCGTTCTTCCTGTCGCGGCGCTCGCTGAAAGCTTCGGTCCATTCGGGAATGC
CGCTATGGCAGGACAAGCTGTTCATCCTGCTTGCACGCACAGCTTCCGATGCCACCGAATATTTCCAGATCCCGACCGGG
CGGGTGGTCGAGATCGGAACACAGGTGAATATCTAA

Upstream 100 bases:

>100_bases
TGTCGCAAAGTGCAACTTTTTTCGCCCGTCCACATTATTCCATCCTGACCCTCAGTCTCTCCGGCCAGTACACTTTCAGG
AAATTGCGAGGTGCCTGCAT

Downstream 100 bases:

>100_bases
AGCCTTTCCCTTAAAAAAAGGGGTAGAAAAAAGCGCCTTTCGGAAGCTCCCGAAAGGCGCTTTTTGTCTATGGCGCGACC
GGGCAAACGGCTCGCAAAAA

Product: potassium uptake protein

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 651; Mature: 650

Protein sequence:

>651_residues
MSGELNGNDTSAQAAVSAGSVLEGAAFADEGEQHNESMKTLVLGALGVVYGDIGTSPIYAFREALHAAATNGILARSDIL
GVVSLIFWALTLVVTVKYVLFVLRADNNGEGGILSLMALVRGALKGRPDLILGVGICGAALFFGDAVITPAISVLSAMEG
LEIVAPNLTPFVVPATVVILVTLFSVQKLGTGRVAIVFGPIMALWFVALGASGLWHIFDDPTVMAALNPYYAVRFLTVSP
AVAFVTVGAVFLAMTGAEALYADLGHFGRKPIVRAWLWIVFPCLLLNYFGQAAFILSHGEAAALPFFQMIPSFALWPMVL
LATAATVIASQAVITGAYSVARQAVQLNILPRLEIQHTSEKLHGQIYIPRVNLLLGLAVVILVLGFEKSSNLAAAYGIAV
TGNMLVTTVLLYIVMTRIWNWRVSRALPIILGFLVIDMLFFSANIIKVHEGGWASIGIATVLVLIMWTWVRGTRHLFQKT
RKAEVPLDLIVEQMAKRPPTIVPGTAVFLTGDPKSAPTALMHSLKHYKVLHENNVILTVVTASKPWVASADRARVSQYNE
RFMLVTLTFGYMQQPNILRALGLCRRLGWKFDIMTTSFFLSRRSLKASVHSGMPLWQDKLFILLARTASDATEYFQIPTG
RVVEIGTQVNI

Sequences:

>Translated_651_residues
MSGELNGNDTSAQAAVSAGSVLEGAAFADEGEQHNESMKTLVLGALGVVYGDIGTSPIYAFREALHAAATNGILARSDIL
GVVSLIFWALTLVVTVKYVLFVLRADNNGEGGILSLMALVRGALKGRPDLILGVGICGAALFFGDAVITPAISVLSAMEG
LEIVAPNLTPFVVPATVVILVTLFSVQKLGTGRVAIVFGPIMALWFVALGASGLWHIFDDPTVMAALNPYYAVRFLTVSP
AVAFVTVGAVFLAMTGAEALYADLGHFGRKPIVRAWLWIVFPCLLLNYFGQAAFILSHGEAAALPFFQMIPSFALWPMVL
LATAATVIASQAVITGAYSVARQAVQLNILPRLEIQHTSEKLHGQIYIPRVNLLLGLAVVILVLGFEKSSNLAAAYGIAV
TGNMLVTTVLLYIVMTRIWNWRVSRALPIILGFLVIDMLFFSANIIKVHEGGWASIGIATVLVLIMWTWVRGTRHLFQKT
RKAEVPLDLIVEQMAKRPPTIVPGTAVFLTGDPKSAPTALMHSLKHYKVLHENNVILTVVTASKPWVASADRARVSQYNE
RFMLVTLTFGYMQQPNILRALGLCRRLGWKFDIMTTSFFLSRRSLKASVHSGMPLWQDKLFILLARTASDATEYFQIPTG
RVVEIGTQVNI
>Mature_650_residues
SGELNGNDTSAQAAVSAGSVLEGAAFADEGEQHNESMKTLVLGALGVVYGDIGTSPIYAFREALHAAATNGILARSDILG
VVSLIFWALTLVVTVKYVLFVLRADNNGEGGILSLMALVRGALKGRPDLILGVGICGAALFFGDAVITPAISVLSAMEGL
EIVAPNLTPFVVPATVVILVTLFSVQKLGTGRVAIVFGPIMALWFVALGASGLWHIFDDPTVMAALNPYYAVRFLTVSPA
VAFVTVGAVFLAMTGAEALYADLGHFGRKPIVRAWLWIVFPCLLLNYFGQAAFILSHGEAAALPFFQMIPSFALWPMVLL
ATAATVIASQAVITGAYSVARQAVQLNILPRLEIQHTSEKLHGQIYIPRVNLLLGLAVVILVLGFEKSSNLAAAYGIAVT
GNMLVTTVLLYIVMTRIWNWRVSRALPIILGFLVIDMLFFSANIIKVHEGGWASIGIATVLVLIMWTWVRGTRHLFQKTR
KAEVPLDLIVEQMAKRPPTIVPGTAVFLTGDPKSAPTALMHSLKHYKVLHENNVILTVVTASKPWVASADRARVSQYNER
FMLVTLTFGYMQQPNILRALGLCRRLGWKFDIMTTSFFLSRRSLKASVHSGMPLWQDKLFILLARTASDATEYFQIPTGR
VVEIGTQVNI

Specific function: Transport of potassium into the cell [H]

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family [H]

Homologues:

Organism=Escherichia coli, GI48994960, Length=620, Percent_Identity=45.1612903225806, Blast_Score=528, Evalue=1e-151,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003855
- InterPro:   IPR023051 [H]

Pfam domain/function: PF02705 K_trans [H]

EC number: NA

Molecular weight: Translated: 70488; Mature: 70357

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGELNGNDTSAQAAVSAGSVLEGAAFADEGEQHNESMKTLVLGALGVVYGDIGTSPIYA
CCCCCCCCCCHHHHHHHCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
FREALHAAATNGILARSDILGVVSLIFWALTLVVTVKYVLFVLRADNNGEGGILSLMALV
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHH
RGALKGRPDLILGVGICGAALFFGDAVITPAISVLSAMEGLEIVAPNLTPFVVPATVVIL
HHHHCCCCCEEEEHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHH
VTLFSVQKLGTGRVAIVFGPIMALWFVALGASGLWHIFDDPTVMAALNPYYAVRFLTVSP
HHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCCCEEEEEEECH
AVAFVTVGAVFLAMTGAEALYADLGHFGRKPIVRAWLWIVFPCLLLNYFGQAAFILSHGE
HHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCC
AAALPFFQMIPSFALWPMVLLATAATVIASQAVITGAYSVARQAVQLNILPRLEIQHTSE
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEECCHH
KLHGQIYIPRVNLLLGLAVVILVLGFEKSSNLAAAYGIAVTGNMLVTTVLLYIVMTRIWN
HHCCEEEECHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHH
WRVSRALPIILGFLVIDMLFFSANIIKVHEGGWASIGIATVLVLIMWTWVRGTRHLFQKT
HHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RKAEVPLDLIVEQMAKRPPTIVPGTAVFLTGDPKSAPTALMHSLKHYKVLHENNVILTVV
HCCCCCHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHEEECCCEEEEEE
TASKPWVASADRARVSQYNERFMLVTLTFGYMQQPNILRALGLCRRLGWKFDIMTTSFFL
ECCCCCCCCCHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCEEEEHHHHHHH
SRRSLKASVHSGMPLWQDKLFILLARTASDATEYFQIPTGRVVEIGTQVNI
HHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHEECCCCCEEEECCCCCC
>Mature Secondary Structure 
SGELNGNDTSAQAAVSAGSVLEGAAFADEGEQHNESMKTLVLGALGVVYGDIGTSPIYA
CCCCCCCCCHHHHHHHCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
FREALHAAATNGILARSDILGVVSLIFWALTLVVTVKYVLFVLRADNNGEGGILSLMALV
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHH
RGALKGRPDLILGVGICGAALFFGDAVITPAISVLSAMEGLEIVAPNLTPFVVPATVVIL
HHHHCCCCCEEEEHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHH
VTLFSVQKLGTGRVAIVFGPIMALWFVALGASGLWHIFDDPTVMAALNPYYAVRFLTVSP
HHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCCCEEEEEEECH
AVAFVTVGAVFLAMTGAEALYADLGHFGRKPIVRAWLWIVFPCLLLNYFGQAAFILSHGE
HHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCC
AAALPFFQMIPSFALWPMVLLATAATVIASQAVITGAYSVARQAVQLNILPRLEIQHTSE
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEECCHH
KLHGQIYIPRVNLLLGLAVVILVLGFEKSSNLAAAYGIAVTGNMLVTTVLLYIVMTRIWN
HHCCEEEECHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHH
WRVSRALPIILGFLVIDMLFFSANIIKVHEGGWASIGIATVLVLIMWTWVRGTRHLFQKT
HHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RKAEVPLDLIVEQMAKRPPTIVPGTAVFLTGDPKSAPTALMHSLKHYKVLHENNVILTVV
HCCCCCHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHEEECCCEEEEEE
TASKPWVASADRARVSQYNERFMLVTLTFGYMQQPNILRALGLCRRLGWKFDIMTTSFFL
ECCCCCCCCCHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCEEEEHHHHHHH
SRRSLKASVHSGMPLWQDKLFILLARTASDATEYFQIPTGRVVEIGTQVNI
HHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHEECCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA