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The map label for this gene is cobL [H]

Identifier: 23502161

GI number: 23502161

Start: 1245597

End: 1246802

Strand: Reverse

Name: cobL [H]

Synonym: BR1285

Alternate gene names: 23502161

Gene position: 1246802-1245597 (Counterclockwise)

Preceding gene: 23502166

Following gene: 23502152

Centisome position: 59.15

GC content: 61.11

Gene sequence:

>1206_bases
ATGGGCTGCTGGCTGACGGTAATCGGTATTGGTGAAGACGGGCTGGATGGGCTGGGGCAGGCAGCACGCAATGCTATCGC
CGAAGCACAGGCAATTTTTGGCGGCAAGCGACATCTGGCCTTTCTGGGCAACGACACAGAGGCGGAACGCATCGCATGGC
CTTCGCCCTTCGATGAAGCCTTTGCGGCGATCCATGCGCGCAGAGGCAGGCCCATCGTTGTGCTTGCAAGTGGAGATCCG
ATGTTTTTCGGCGTCGGCGCGTCGCTTGCGAAGCATTTTTCGCCCGATGAGATGCTGGTTCTGCCTTATCCCTCATCGCT
GTCGCTGGCTGCCGCCCGGATGGGCTGGGCGCTTCAGGACGTGCAAACGGTGAGCGTGCATGGCCGCCCCTATGAATTGC
TTGTTCCGCACATTCTGCCGGGTGTGAGGCTTCTGGTGTTGAGCAATGACGGTACGACCCCGGCAAGGGTGGCTACGCTG
CTGGCGGCCATAGGATTTGGGCAAAGCGTCCTGACCGTTCTGGAGCATCTCGGTGGGCCGAAAGAGCGCATCCTCCACGG
CACCGCCGCTAACTGGCTGCATGAGCGATGTGCGGACCTTCATGTGCTCGCCATCGCGTGTATTGCCGCGCCGGATGCGG
CTGTTTTGTCGCCTGTTGCGGGATTGCCCGATGAGGCGTTTGAAAATGATGGCCAGCTTACCAAGCGCGATATCCGTGCT
GTCACGCTTTCGCGATTGCAGCCCTTGCCGCACCAGCTTCTTTGGGATGTGGGCGCAGGCTGCGGCTCCATCGGCATCGA
ATGGATGCGTGTTCATGCCTCATGCCGGGCAATTGCAATCGAGGCCGATGAGGGACGGCAAGGCATGATCGAGCGCAACC
GGGTGGCACTTGGCGTTCCCGGTTTGCAGCTTGTGCAAGGCAGGGCGCCTTCCGCGCTGCGCGGGCTTGAAGCGCCGGAC
GCAATTTTCATTGGCGGCGGCGTGACGGATGAAGGTGTGCTGGAAGCCTGCTGGAATGCCCTGAAACCGGGCGGACGGCT
GGTTGCCAATGCCGTGACCTTGCAAAGCGAAATGCGGCTTTTCGCCTGGCGGCAGGAATTTGGCGGTGATCTGACCCGCG
TTGGTGTTGCACAGGCGGGCGAACTCGGCTCGTTCGATGTCTGGCGTCAGGCGCTCCCCGTCACGATTTATTGCGGGTTC
AAATGA

Upstream 100 bases:

>100_bases
GTTCTGGATGGTTTGCTGGTTCAACATGGGGGTCTTATACGCCTTGGCGCTTGCACTTGCTACCGCCCCGCCATACGAAC
AGGGAAAAGGAGCGTTGCGC

Downstream 100 bases:

>100_bases
CGAGATCGTGGGCCTCAAGCGGCTCCACCACCTCGCCATTGCGCATTACGGCCAGCCGGTCGCTCCTATCGTGACGACGG
CTAAAGCATATCTTCCAGAG

Product: precorrin-6Y C5,15-methyltransferase

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MGCWLTVIGIGEDGLDGLGQAARNAIAEAQAIFGGKRHLAFLGNDTEAERIAWPSPFDEAFAAIHARRGRPIVVLASGDP
MFFGVGASLAKHFSPDEMLVLPYPSSLSLAAARMGWALQDVQTVSVHGRPYELLVPHILPGVRLLVLSNDGTTPARVATL
LAAIGFGQSVLTVLEHLGGPKERILHGTAANWLHERCADLHVLAIACIAAPDAAVLSPVAGLPDEAFENDGQLTKRDIRA
VTLSRLQPLPHQLLWDVGAGCGSIGIEWMRVHASCRAIAIEADEGRQGMIERNRVALGVPGLQLVQGRAPSALRGLEAPD
AIFIGGGVTDEGVLEACWNALKPGGRLVANAVTLQSEMRLFAWRQEFGGDLTRVGVAQAGELGSFDVWRQALPVTIYCGF
K

Sequences:

>Translated_401_residues
MGCWLTVIGIGEDGLDGLGQAARNAIAEAQAIFGGKRHLAFLGNDTEAERIAWPSPFDEAFAAIHARRGRPIVVLASGDP
MFFGVGASLAKHFSPDEMLVLPYPSSLSLAAARMGWALQDVQTVSVHGRPYELLVPHILPGVRLLVLSNDGTTPARVATL
LAAIGFGQSVLTVLEHLGGPKERILHGTAANWLHERCADLHVLAIACIAAPDAAVLSPVAGLPDEAFENDGQLTKRDIRA
VTLSRLQPLPHQLLWDVGAGCGSIGIEWMRVHASCRAIAIEADEGRQGMIERNRVALGVPGLQLVQGRAPSALRGLEAPD
AIFIGGGVTDEGVLEACWNALKPGGRLVANAVTLQSEMRLFAWRQEFGGDLTRVGVAQAGELGSFDVWRQALPVTIYCGF
K
>Mature_400_residues
GCWLTVIGIGEDGLDGLGQAARNAIAEAQAIFGGKRHLAFLGNDTEAERIAWPSPFDEAFAAIHARRGRPIVVLASGDPM
FFGVGASLAKHFSPDEMLVLPYPSSLSLAAARMGWALQDVQTVSVHGRPYELLVPHILPGVRLLVLSNDGTTPARVATLL
AAIGFGQSVLTVLEHLGGPKERILHGTAANWLHERCADLHVLAIACIAAPDAAVLSPVAGLPDEAFENDGQLTKRDIRAV
TLSRLQPLPHQLLWDVGAGCGSIGIEWMRVHASCRAIAIEADEGRQGMIERNRVALGVPGLQLVQGRAPSALRGLEAPDA
IFIGGGVTDEGVLEACWNALKPGGRLVANAVTLQSEMRLFAWRQEFGGDLTRVGVAQAGELGSFDVWRQALPVTIYCGFK

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2241

COG function: function code H; Precorrin-6B methylase 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 42618; Mature: 42486

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGCWLTVIGIGEDGLDGLGQAARNAIAEAQAIFGGKRHLAFLGNDTEAERIAWPSPFDEA
CCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHH
FAAIHARRGRPIVVLASGDPMFFGVGASLAKHFSPDEMLVLPYPSSLSLAAARMGWALQD
HHHHHHCCCCEEEEEECCCCEEEECCHHHHHCCCCCCEEEEECCCCHHHHHHHHCCHHHC
VQTVSVHGRPYELLVPHILPGVRLLVLSNDGTTPARVATLLAAIGFGQSVLTVLEHLGGP
EEEEEECCCCCEEECCHHCCCEEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCC
KERILHGTAANWLHERCADLHVLAIACIAAPDAAVLSPVAGLPDEAFENDGQLTKRDIRA
HHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHCCCCCHHHHHHHH
VTLSRLQPLPHQLLWDVGAGCGSIGIEWMRVHASCRAIAIEADEGRQGMIERNRVALGVP
HHHHHCCCCHHHHHHHHCCCCCHHCHHHEEEECCEEEEEEECCCCCCCCCCCCCEEEECC
GLQLVQGRAPSALRGLEAPDAIFIGGGVTDEGVLEACWNALKPGGRLVANAVTLQSEMRL
CHHHHCCCCCHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
FAWRQEFGGDLTRVGVAQAGELGSFDVWRQALPVTIYCGFK
HHHHHHHCCCEEEECHHCCCCCCCHHHHHHCCCEEEEECCC
>Mature Secondary Structure 
GCWLTVIGIGEDGLDGLGQAARNAIAEAQAIFGGKRHLAFLGNDTEAERIAWPSPFDEA
CEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHH
FAAIHARRGRPIVVLASGDPMFFGVGASLAKHFSPDEMLVLPYPSSLSLAAARMGWALQD
HHHHHHCCCCEEEEEECCCCEEEECCHHHHHCCCCCCEEEEECCCCHHHHHHHHCCHHHC
VQTVSVHGRPYELLVPHILPGVRLLVLSNDGTTPARVATLLAAIGFGQSVLTVLEHLGGP
EEEEEECCCCCEEECCHHCCCEEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCC
KERILHGTAANWLHERCADLHVLAIACIAAPDAAVLSPVAGLPDEAFENDGQLTKRDIRA
HHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHCCCCCHHHHHHHH
VTLSRLQPLPHQLLWDVGAGCGSIGIEWMRVHASCRAIAIEADEGRQGMIERNRVALGVP
HHHHHCCCCHHHHHHHHCCCCCHHCHHHEEEECCEEEEEEECCCCCCCCCCCCCEEEECC
GLQLVQGRAPSALRGLEAPDAIFIGGGVTDEGVLEACWNALKPGGRLVANAVTLQSEMRL
CHHHHCCCCCHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
FAWRQEFGGDLTRVGVAQAGELGSFDVWRQALPVTIYCGFK
HHHHHHHCCCEEEECHHCCCCCCCHHHHHHCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]