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The map label for this gene is yaeL [C]

Identifier: 23502034

GI number: 23502034

Start: 1136004

End: 1137143

Strand: Reverse

Name: yaeL [C]

Synonym: BR1156

Alternate gene names: 23502034

Gene position: 1137143-1136004 (Counterclockwise)

Preceding gene: 23502035

Following gene: 23502033

Centisome position: 53.95

GC content: 57.11

Gene sequence:

>1140_bases
TTGCAGGAGGCTCTGGCCCTGTTTTTCGGTAGCGAAAGTCTGTTGGTCGGGACAATCATACCGTTTCTGTTCGTTTTGAC
CGTCGTGGTGTTCGTTCATGAGATGGGCCACTATCTCGTTGCGCGGTGGTGCGGCATCGGAGCCCAGGCTTTTTCCATCG
GCTTCGGGCCGGAACTGCTGGGCTTCACCGACCGCCATGGAACGCGGTGGAAACTTTCGGCCATCCCCCTCGGCGGTTAT
GTGAAGTTTATCGGCGATGAGAGCGAAACCAGCTCGCCTGTAGGCGTCAACGAGAGTGCTCTCAGCGAAGAGGACCGCAA
GCGGGCCTTTCATACCCAACCCGTCTGGAAACGCGCGGCGACGGTTTTTGCAGGTCCGGCGTTCAATATCATTCTTACCA
TTGCAATCTTCAGTGTTTTCTTTGCGCTTTATGGGCGCCAGATCGCCGATCCGCTGATTGCGGGCGTACAGCCGGGAAGC
CCGGCAGCCGAAGCCGGGTTTGAACCGGGGGACCGCTTCGTCAGCGTGGAGGGCGAGAAGATAACGACTTTCGCCGATGT
GCAGCGCATCGTTTCAGGCCGTGCCGGCGACAAGCTGAATTTTACCGTCGAGCGTGACGGCAAGATGGTGGACCTTCAGG
CAGTGCCGAAGATTGTCGAGCGGACCGATCCGCTTGGCAACAAGGTGAAGCTTGGCGCTATCGGCGTTGAAACCACGGAA
GCTGTGGGCAATTTCCGGCGTATTGAATATGGCCCGCTCGAATCGGTGGGGCAGGCCGTCATTGAAACCGGCCATATTAT
CGGTCGGACCGGCGAGTTCTTCAAACGTTTCGCCGTGGGGCGCGAAGACAAGTGCCAGCTTGGCGGACCTGTGAAGATTG
CCACTATGGCCAGCAAGGCGGCAAGCCAGGGGTTTGACTGGCTGATACAATTGATGGCCATGCTATCCATCGGTATCGGG
CTGTTGAACCTGTTTCCGCTCCCGCCGCTCGATGGGGGACATCTGGTTTTCTATGCGGTGGAGGCAATCAAGGGCAGCCC
TGTTTCAGGTGCGGCGCAGGAAATTTTTTATCGCATCGGTTTTCTCCTTGTCATGGGATTTATGGGGTTCGTACTTTTCA
ACGACCTTTTTGCCTGCTAG

Upstream 100 bases:

>100_bases
AGATGTTCCGTCTGCAATCTTCTTTAGTTTCTGACCGCTTTTATGGTCTGTCGGCTGACCGGAACCGCTCAGTCGATGAA
AGTTTGGTAGGAGTAGTAAT

Downstream 100 bases:

>100_bases
ATCAATGACCGGCTGGTTTTTGGTGGTAATTGAAAATAGGGGTCGGAGCGGACGATTTCGGCAGATCATTTGCCATAATG
CAGCGCAGACCCGGCTGATC

Product: membrane-associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MQEALALFFGSESLLVGTIIPFLFVLTVVVFVHEMGHYLVARWCGIGAQAFSIGFGPELLGFTDRHGTRWKLSAIPLGGY
VKFIGDESETSSPVGVNESALSEEDRKRAFHTQPVWKRAATVFAGPAFNIILTIAIFSVFFALYGRQIADPLIAGVQPGS
PAAEAGFEPGDRFVSVEGEKITTFADVQRIVSGRAGDKLNFTVERDGKMVDLQAVPKIVERTDPLGNKVKLGAIGVETTE
AVGNFRRIEYGPLESVGQAVIETGHIIGRTGEFFKRFAVGREDKCQLGGPVKIATMASKAASQGFDWLIQLMAMLSIGIG
LLNLFPLPPLDGGHLVFYAVEAIKGSPVSGAAQEIFYRIGFLLVMGFMGFVLFNDLFAC

Sequences:

>Translated_379_residues
MQEALALFFGSESLLVGTIIPFLFVLTVVVFVHEMGHYLVARWCGIGAQAFSIGFGPELLGFTDRHGTRWKLSAIPLGGY
VKFIGDESETSSPVGVNESALSEEDRKRAFHTQPVWKRAATVFAGPAFNIILTIAIFSVFFALYGRQIADPLIAGVQPGS
PAAEAGFEPGDRFVSVEGEKITTFADVQRIVSGRAGDKLNFTVERDGKMVDLQAVPKIVERTDPLGNKVKLGAIGVETTE
AVGNFRRIEYGPLESVGQAVIETGHIIGRTGEFFKRFAVGREDKCQLGGPVKIATMASKAASQGFDWLIQLMAMLSIGIG
LLNLFPLPPLDGGHLVFYAVEAIKGSPVSGAAQEIFYRIGFLLVMGFMGFVLFNDLFAC
>Mature_379_residues
MQEALALFFGSESLLVGTIIPFLFVLTVVVFVHEMGHYLVARWCGIGAQAFSIGFGPELLGFTDRHGTRWKLSAIPLGGY
VKFIGDESETSSPVGVNESALSEEDRKRAFHTQPVWKRAATVFAGPAFNIILTIAIFSVFFALYGRQIADPLIAGVQPGS
PAAEAGFEPGDRFVSVEGEKITTFADVQRIVSGRAGDKLNFTVERDGKMVDLQAVPKIVERTDPLGNKVKLGAIGVETTE
AVGNFRRIEYGPLESVGQAVIETGHIIGRTGEFFKRFAVGREDKCQLGGPVKIATMASKAASQGFDWLIQLMAMLSIGIG
LLNLFPLPPLDGGHLVFYAVEAIKGSPVSGAAQEIFYRIGFLLVMGFMGFVLFNDLFAC

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain

Homologues:

Organism=Escherichia coli, GI1786373, Length=234, Percent_Identity=35.4700854700855, Blast_Score=133, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1156_BRUSU (Q8G0E1)

Other databases:

- EMBL:   AE014291
- RefSeq:   NP_698161.1
- ProteinModelPortal:   Q8G0E1
- SMR:   Q8G0E1
- MEROPS:   M50.004
- GeneID:   1166832
- GenomeReviews:   AE014291_GR
- KEGG:   bms:BR1156
- TIGR:   BR1156
- HOGENOM:   HBG664087
- OMA:   HGTEFVV
- PhylomeDB:   Q8G0E1
- ProtClustDB:   CLSK863040
- BioCyc:   BSUI204722:BR_1156-MONOMER
- GO:   GO:0006508
- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915
- SMART:   SM00228
- TIGRFAMs:   TIGR00054

Pfam domain/function: PF02163 Peptidase_M50; SSF50156 PDZ

EC number: NA

Molecular weight: Translated: 40935; Mature: 40935

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS50106 PDZ; PS00142 ZINC_PROTEASE

Important sites: ACT_SITE 34-34

Signals:

None

Transmembrane regions:

HASH(0xdf42414)-; HASH(0xc7174c0)-; HASH(0xe37a4e8)-; HASH(0xdce8198)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEALALFFGSESLLVGTIIPFLFVLTVVVFVHEMGHYLVARWCGIGAQAFSIGFGPELL
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEECCCCHHHC
GFTDRHGTRWKLSAIPLGGYVKFIGDESETSSPVGVNESALSEEDRKRAFHTQPVWKRAA
CCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCHHHHCHHHHHHHHCCCHHHHHHH
TVFAGPAFNIILTIAIFSVFFALYGRQIADPLIAGVQPGSPAAEAGFEPGDRFVSVEGEK
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCEEEECCCE
ITTFADVQRIVSGRAGDKLNFTVERDGKMVDLQAVPKIVERTDPLGNKVKLGAIGVETTE
EHHHHHHHHHHCCCCCCCEEEEEECCCCEEEHHHHHHHHHHCCCCCCEEEEEEECCCHHH
AVGNFRRIEYGPLESVGQAVIETGHIIGRTGEFFKRFAVGREDKCQLGGPVKIATMASKA
HHCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCEEEHHHHHHH
ASQGFDWLIQLMAMLSIGIGLLNLFPLPPLDGGHLVFYAVEAIKGSPVSGAAQEIFYRIG
HHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEHHCCCCCCHHHHHHHHHHH
FLLVMGFMGFVLFNDLFAC
HHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MQEALALFFGSESLLVGTIIPFLFVLTVVVFVHEMGHYLVARWCGIGAQAFSIGFGPELL
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEECCCCHHHC
GFTDRHGTRWKLSAIPLGGYVKFIGDESETSSPVGVNESALSEEDRKRAFHTQPVWKRAA
CCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCHHHHCHHHHHHHHCCCHHHHHHH
TVFAGPAFNIILTIAIFSVFFALYGRQIADPLIAGVQPGSPAAEAGFEPGDRFVSVEGEK
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCEEEECCCE
ITTFADVQRIVSGRAGDKLNFTVERDGKMVDLQAVPKIVERTDPLGNKVKLGAIGVETTE
EHHHHHHHHHHCCCCCCCEEEEEECCCCEEEHHHHHHHHHHCCCCCCEEEEEEECCCHHH
AVGNFRRIEYGPLESVGQAVIETGHIIGRTGEFFKRFAVGREDKCQLGGPVKIATMASKA
HHCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCEEEHHHHHHH
ASQGFDWLIQLMAMLSIGIGLLNLFPLPPLDGGHLVFYAVEAIKGSPVSGAAQEIFYRIG
HHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEHHCCCCCCHHHHHHHHHHH
FLLVMGFMGFVLFNDLFAC
HHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12271122