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The map label for this gene is hfq [H]

Identifier: 23501989

GI number: 23501989

Start: 1087977

End: 1088213

Strand: Reverse

Name: hfq [H]

Synonym: BR1111

Alternate gene names: 23501989

Gene position: 1088213-1087977 (Counterclockwise)

Preceding gene: 23501990

Following gene: 23501988

Centisome position: 51.63

GC content: 45.57

Gene sequence:

>237_bases
ATGGCTGAACGATCGCAAAATCTACAAGACCTCTTTCTGAATTCTGTCCGCAAGCAGAAGATTTCTCTAACGATCTTCCT
TATCAATGGCGTGAAATTGACCGGCATTGTAACGTCTTTCGATAATTTCTGCGTGCTTCTGCGTCGTGATGGTCATTCGC
AGCTTGTTTACAAGCATGCTATTTCGACAATCATGCCGAGCCAGCCTGTACAGATGTTTGAAGGCGAGGAAGCCTGA

Upstream 100 bases:

>100_bases
GGTATCGGTTTTGCACACGCGGGTGCTTGATTTATGCGCATGTGCGTGTTCGTTTATCATATCGCGAGCTGGCTGCTGAT
CGATTAAAGGAATAAAAACA

Downstream 100 bases:

>100_bases
CGCTTTCCGATATTTGCCGGGGCGTGGTAAGTATCCCGCCCCAGCTTTTGTTTGAGTATGTTTCGGCCAGAAAGCGCATC
GCTATCGGGCATTGCTTGAA

Product: RNA-binding protein Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 78; Mature: 77

Protein sequence:

>78_residues
MAERSQNLQDLFLNSVRKQKISLTIFLINGVKLTGIVTSFDNFCVLLRRDGHSQLVYKHAISTIMPSQPVQMFEGEEA

Sequences:

>Translated_78_residues
MAERSQNLQDLFLNSVRKQKISLTIFLINGVKLTGIVTSFDNFCVLLRRDGHSQLVYKHAISTIMPSQPVQMFEGEEA
>Mature_77_residues
AERSQNLQDLFLNSVRKQKISLTIFLINGVKLTGIVTSFDNFCVLLRRDGHSQLVYKHAISTIMPSQPVQMFEGEEA

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs [H]

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family [H]

Homologues:

Organism=Escherichia coli, GI1790614, Length=67, Percent_Identity=52.2388059701493, Blast_Score=82, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163 [H]

Pfam domain/function: PF01423 LSM [H]

EC number: NA

Molecular weight: Translated: 8854; Mature: 8723

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERSQNLQDLFLNSVRKQKISLTIFLINGVKLTGIVTSFDNFCVLLRRDGHSQLVYKHA
CCCCCCCHHHHHHHHHCCCEEEEEEEEECCEEEEEEEECCCCEEEEEEECCCCHHHHHHH
ISTIMPSQPVQMFEGEEA
HHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AERSQNLQDLFLNSVRKQKISLTIFLINGVKLTGIVTSFDNFCVLLRRDGHSQLVYKHA
CCCCCCHHHHHHHHHCCCEEEEEEEEECCEEEEEEEECCCCEEEEEEECCCCHHHHHHH
ISTIMPSQPVQMFEGEEA
HHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA