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The map label for this gene is corA [H]

Identifier: 23501448

GI number: 23501448

Start: 553546

End: 554538

Strand: Reverse

Name: corA [H]

Synonym: BR0559

Alternate gene names: 23501448

Gene position: 554538-553546 (Counterclockwise)

Preceding gene: 23501451

Following gene: 23501447

Centisome position: 26.31

GC content: 55.79

Gene sequence:

>993_bases
ATGATTACGCTTTACTGTCTTTCCGGGGACCATCTAGAGCAAATTGACGTCGAGCCGGGGACACCCCTGCCCGACAATGT
GATCTGGATCGATATTTTCACGCCTGGCGTCAGCGAAGACCATATTGTCGAGGCCTGGACAGGCATCTCCATCCCGACAC
GCGAAGACATGACGGAGATTGAGGAATCGAGCCGTTTTTATATGGAATCCGGAGCGCAATATCTGACGGTGCCTATCCTC
CATGCGGTCGATCTCGACCATCGTGAACTCGCACCCGTCACCTTCATCACGCATGGCGCGCGGCTCATCACGGTTCGCTA
TGCCAATCCCAAATCATTCAGCATCTATATTTCGCGCGTAACCAAGCCCGGCAACGGGCTCATACCCGCCAAATGCACCG
GCATATCGATCATGCTGGGCATCATCGAGGCCACGACAAACCGGCTGGCCGATATTCTGGAAGGCGTGGCAGGCAAGATC
GATGCGGCCTCCCATTCGATCTATCGCCGCCAGCCCAAGGCCCACCCGATGACGACAGAGGATTTCAGACATGTCCTCAC
CCAGATCGGCGGACAGGGAACATTCCTGTCGCGAACACGGGAAAGCCTTGCCGGCTTGAGCCGCATGCTCGTCTATCTCT
CGGCCAACAACAGTCCCGTTTCAGCCAAGAAAGACACGCGCTCCTGGATCAAATCGCTGGAGCGCGACGCCCAATCCCTC
ACGGCCTATGTGGATTTTCTGGCCAATAAAGTGACATTCCTGCTCGATACGATCGTAGGGCTCATCTCGGTTGAACAGAA
CGCCATCATCAAGATATTTTCCGTGGCTGCCGTCGGCTTCATGCCGCCAACACTTGTTGCATCCATCTATGGCATGAATT
TTTCCTTCATGCCGGAACTGCACTCGCCCTGGGGTTATCCGATGGCGCTGATATTCATGGTCGCCTCGGCCCTGCTGCCG
CTGCTTTATTTCCGCAGCAAGGGGTGGCTCTGA

Upstream 100 bases:

>100_bases
CAACGCCCCCTTTTGCCGAGGCGATGGCCTATGCCGTATTCCGTTAACAATTTTCGCGCAATCTGCGTTTCATTTCGCAG
CTTCGCAGTCAGGTGCCAGC

Downstream 100 bases:

>100_bases
CAATTCTCGACAGGCTTCCCCTCCCATGTTATATCATCTGTCATAACATGGGAGAAAGCCATGAACATAACCCTGCGCAA
GATCGGTAATTCCTATGGGG

Product: CorA family protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MITLYCLSGDHLEQIDVEPGTPLPDNVIWIDIFTPGVSEDHIVEAWTGISIPTREDMTEIEESSRFYMESGAQYLTVPIL
HAVDLDHRELAPVTFITHGARLITVRYANPKSFSIYISRVTKPGNGLIPAKCTGISIMLGIIEATTNRLADILEGVAGKI
DAASHSIYRRQPKAHPMTTEDFRHVLTQIGGQGTFLSRTRESLAGLSRMLVYLSANNSPVSAKKDTRSWIKSLERDAQSL
TAYVDFLANKVTFLLDTIVGLISVEQNAIIKIFSVAAVGFMPPTLVASIYGMNFSFMPELHSPWGYPMALIFMVASALLP
LLYFRSKGWL

Sequences:

>Translated_330_residues
MITLYCLSGDHLEQIDVEPGTPLPDNVIWIDIFTPGVSEDHIVEAWTGISIPTREDMTEIEESSRFYMESGAQYLTVPIL
HAVDLDHRELAPVTFITHGARLITVRYANPKSFSIYISRVTKPGNGLIPAKCTGISIMLGIIEATTNRLADILEGVAGKI
DAASHSIYRRQPKAHPMTTEDFRHVLTQIGGQGTFLSRTRESLAGLSRMLVYLSANNSPVSAKKDTRSWIKSLERDAQSL
TAYVDFLANKVTFLLDTIVGLISVEQNAIIKIFSVAAVGFMPPTLVASIYGMNFSFMPELHSPWGYPMALIFMVASALLP
LLYFRSKGWL
>Mature_330_residues
MITLYCLSGDHLEQIDVEPGTPLPDNVIWIDIFTPGVSEDHIVEAWTGISIPTREDMTEIEESSRFYMESGAQYLTVPIL
HAVDLDHRELAPVTFITHGARLITVRYANPKSFSIYISRVTKPGNGLIPAKCTGISIMLGIIEATTNRLADILEGVAGKI
DAASHSIYRRQPKAHPMTTEDFRHVLTQIGGQGTFLSRTRESLAGLSRMLVYLSANNSPVSAKKDTRSWIKSLERDAQSL
TAYVDFLANKVTFLLDTIVGLISVEQNAIIKIFSVAAVGFMPPTLVASIYGMNFSFMPELHSPWGYPMALIFMVASALLP
LLYFRSKGWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=331, Percent_Identity=32.02416918429, Blast_Score=167, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 36523; Mature: 36523

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLYCLSGDHLEQIDVEPGTPLPDNVIWIDIFTPGVSEDHIVEAWTGISIPTREDMTEI
CEEEEEECCCCCEEEECCCCCCCCCCEEEEEEECCCCCCCCHHHHCCCCCCCCHHHHHHH
EESSRFYMESGAQYLTVPILHAVDLDHRELAPVTFITHGARLITVRYANPKSFSIYISRV
HHHHHHHHHCCCCEEEEEEHHHCCCCCCCCCCEEEEECCEEEEEEEECCCCCEEEEEEEE
TKPGNGLIPAKCTGISIMLGIIEATTNRLADILEGVAGKIDAASHSIYRRQPKAHPMTTE
CCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHH
DFRHVLTQIGGQGTFLSRTRESLAGLSRMLVYLSANNSPVSAKKDTRSWIKSLERDAQSL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
TAYVDFLANKVTFLLDTIVGLISVEQNAIIKIFSVAAVGFMPPTLVASIYGMNFSFMPEL
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCEECCCC
HSPWGYPMALIFMVASALLPLLYFRSKGWL
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MITLYCLSGDHLEQIDVEPGTPLPDNVIWIDIFTPGVSEDHIVEAWTGISIPTREDMTEI
CEEEEEECCCCCEEEECCCCCCCCCCEEEEEEECCCCCCCCHHHHCCCCCCCCHHHHHHH
EESSRFYMESGAQYLTVPILHAVDLDHRELAPVTFITHGARLITVRYANPKSFSIYISRV
HHHHHHHHHCCCCEEEEEEHHHCCCCCCCCCCEEEEECCEEEEEEEECCCCCEEEEEEEE
TKPGNGLIPAKCTGISIMLGIIEATTNRLADILEGVAGKIDAASHSIYRRQPKAHPMTTE
CCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHH
DFRHVLTQIGGQGTFLSRTRESLAGLSRMLVYLSANNSPVSAKKDTRSWIKSLERDAQSL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
TAYVDFLANKVTFLLDTIVGLISVEQNAIIKIFSVAAVGFMPPTLVASIYGMNFSFMPEL
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCEECCCC
HSPWGYPMALIFMVASALLPLLYFRSKGWL
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA