Click here to switch to the map view.

The map label for this gene is fadB1 [H]

Identifier: 23501315

GI number: 23501315

Start: 414960

End: 415712

Strand: Reverse

Name: fadB1 [H]

Synonym: BR0411

Alternate gene names: 23501315

Gene position: 415712-414960 (Counterclockwise)

Preceding gene: 23501316

Following gene: 23501313

Centisome position: 19.72

GC content: 60.56

Gene sequence:

>753_bases
ATGAGCGAACATATCCTGATCGAGCGTAAAGGGGCGGTGCAGGTCATCCGCCTCAACCGGCCTGAAAAGAAAAATGCCAT
CACGCGCGCCATGTATGCGGCCATGGCAAAGGCGCTCAAGGACGGCGACGCGGACGATGCCGTGCGCGCGCATGTTTTCC
TCGGTGTTCCGGGCGCTTTTTCTTCCGGCAATGACATGCAGGATTTCATGGCCGCGGCCACGGGCGACACCAGCTTCGGC
AGCGAAATTCTGGATTTCCTCATTCCGCTCGCTGAAACCAAAAAGCCGATTGTTTCAGGCGTCGATGGGCTTGCCATTGG
CGTCGGCACGACGATCCATTTTCACTGCGACCTGACCTTTGCCACGCCGCGCGCGCTGTTCCGCACGCCGTTTGTCGATC
TCGGCCTCGTGCCGGAGGCAGGCTCCAGCCTGCTTGCGCCCTTGCTGATGGGGCATCAGAAAGCCTTCGCGCTGCTGGCG
CTCGGTCATGGTTTTACGGCGGAAGCCGCGCAGAAGTCCGGTATTGTCTACCAGATCGTGGACGAAGAGGCGCTGGAAGC
GGAAGTGATGAAGGCCGCGGAAGAAATTGCCGCCAAACCGCCGCAGGCCATGCAGATCGCCCGCGCCCTGATGCGCCTTC
CCGCCGAAAACATCGCTGACCGCATTACCCGCGAAGCCAAGCATTTTGCCGAGCGGCTCACCTCCGATGAGGCCCGCGAA
GCCGTGATGGCTTTTCTCAGCCGCAAAAAATAA

Upstream 100 bases:

>100_bases
TTGCCGAAAACATGCTGGCCGAAGTTTCTTCGCTGAAAGACACTGTTATCACCGGCGCTGCCAGCCTTACCGCTGCAAAA
TCGGCGCTGGAGGCGTGAAA

Downstream 100 bases:

>100_bases
ACCCGGATGTCCTCTTTTATGGGCGCATCTTTTCCGAAAACCGGTTTCCACTTTTCGGGATGCGCCCCAAGACATCCGGG
GGCTTATGGAGGTCAGCCAA

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MSEHILIERKGAVQVIRLNRPEKKNAITRAMYAAMAKALKDGDADDAVRAHVFLGVPGAFSSGNDMQDFMAAATGDTSFG
SEILDFLIPLAETKKPIVSGVDGLAIGVGTTIHFHCDLTFATPRALFRTPFVDLGLVPEAGSSLLAPLLMGHQKAFALLA
LGHGFTAEAAQKSGIVYQIVDEEALEAEVMKAAEEIAAKPPQAMQIARALMRLPAENIADRITREAKHFAERLTSDEARE
AVMAFLSRKK

Sequences:

>Translated_250_residues
MSEHILIERKGAVQVIRLNRPEKKNAITRAMYAAMAKALKDGDADDAVRAHVFLGVPGAFSSGNDMQDFMAAATGDTSFG
SEILDFLIPLAETKKPIVSGVDGLAIGVGTTIHFHCDLTFATPRALFRTPFVDLGLVPEAGSSLLAPLLMGHQKAFALLA
LGHGFTAEAAQKSGIVYQIVDEEALEAEVMKAAEEIAAKPPQAMQIARALMRLPAENIADRITREAKHFAERLTSDEARE
AVMAFLSRKK
>Mature_249_residues
SEHILIERKGAVQVIRLNRPEKKNAITRAMYAAMAKALKDGDADDAVRAHVFLGVPGAFSSGNDMQDFMAAATGDTSFGS
EILDFLIPLAETKKPIVSGVDGLAIGVGTTIHFHCDLTFATPRALFRTPFVDLGLVPEAGSSLLAPLLMGHQKAFALLAL
GHGFTAEAAQKSGIVYQIVDEEALEAEVMKAAEEIAAKPPQAMQIARALMRLPAENIADRITREAKHFAERLTSDEAREA
VMAFLSRKK

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI260274832, Length=253, Percent_Identity=32.0158102766798, Blast_Score=124, Evalue=6e-29,
Organism=Homo sapiens, GI45643119, Length=253, Percent_Identity=32.0158102766798, Blast_Score=124, Evalue=7e-29,
Organism=Homo sapiens, GI260275230, Length=253, Percent_Identity=32.0158102766798, Blast_Score=124, Evalue=7e-29,
Organism=Homo sapiens, GI194097323, Length=252, Percent_Identity=28.5714285714286, Blast_Score=111, Evalue=6e-25,
Organism=Homo sapiens, GI25453481, Length=251, Percent_Identity=27.4900398406374, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI51538573, Length=251, Percent_Identity=27.4900398406374, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI4757966, Length=214, Percent_Identity=29.9065420560748, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI51538581, Length=214, Percent_Identity=29.9065420560748, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4757968, Length=251, Percent_Identity=27.8884462151394, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI49355787, Length=251, Percent_Identity=27.8884462151394, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI221136756, Length=251, Percent_Identity=25.8964143426295, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI221136753, Length=251, Percent_Identity=25.8964143426295, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI221307494, Length=251, Percent_Identity=25.8964143426295, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI116235487, Length=251, Percent_Identity=24.3027888446215, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI20127408, Length=184, Percent_Identity=29.3478260869565, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI68989263, Length=204, Percent_Identity=28.921568627451, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI70995211, Length=250, Percent_Identity=25.6, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI31542718, Length=246, Percent_Identity=25.2032520325203, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI62530384, Length=262, Percent_Identity=22.9007633587786, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787660, Length=257, Percent_Identity=31.1284046692607, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1787659, Length=254, Percent_Identity=25.5905511811024, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI221142681, Length=258, Percent_Identity=28.2945736434109, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1788597, Length=198, Percent_Identity=27.7777777777778, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17535521, Length=251, Percent_Identity=31.0756972111554, Blast_Score=132, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17549921, Length=211, Percent_Identity=36.9668246445498, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17554946, Length=257, Percent_Identity=30.7392996108949, Blast_Score=113, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI25145438, Length=249, Percent_Identity=24.8995983935743, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17536985, Length=268, Percent_Identity=26.865671641791, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17534483, Length=251, Percent_Identity=25.8964143426295, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17558304, Length=180, Percent_Identity=30, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560910, Length=207, Percent_Identity=24.6376811594203, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17540714, Length=237, Percent_Identity=22.7848101265823, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320241, Length=209, Percent_Identity=26.7942583732057, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24654903, Length=252, Percent_Identity=30.5555555555556, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI20129971, Length=251, Percent_Identity=27.0916334661355, Blast_Score=103, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24653477, Length=251, Percent_Identity=27.0916334661355, Blast_Score=103, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24653139, Length=258, Percent_Identity=25.1937984496124, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI21357171, Length=193, Percent_Identity=26.4248704663212, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19922422, Length=250, Percent_Identity=22.4, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24650670, Length=184, Percent_Identity=23.9130434782609, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19920382, Length=208, Percent_Identity=26.4423076923077, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 26898; Mature: 26767

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEHILIERKGAVQVIRLNRPEKKNAITRAMYAAMAKALKDGDADDAVRAHVFLGVPGAF
CCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEEEECCCCC
SSGNDMQDFMAAATGDTSFGSEILDFLIPLAETKKPIVSGVDGLAIGVGTTIHFHCDLTF
CCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHCCCCCEEEEECCEEEEEEEEEE
ATPRALFRTPFVDLGLVPEAGSSLLAPLLMGHQKAFALLALGHGFTAEAAQKSGIVYQIV
CCHHHHHHCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHCCCEEEEC
DEEALEAEVMKAAEEIAAKPPQAMQIARALMRLPAENIADRITREAKHFAERLTSDEARE
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHH
AVMAFLSRKK
HHHHHHHCCC
>Mature Secondary Structure 
SEHILIERKGAVQVIRLNRPEKKNAITRAMYAAMAKALKDGDADDAVRAHVFLGVPGAF
CCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEEEECCCCC
SSGNDMQDFMAAATGDTSFGSEILDFLIPLAETKKPIVSGVDGLAIGVGTTIHFHCDLTF
CCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHCCCCCEEEEECCEEEEEEEEEE
ATPRALFRTPFVDLGLVPEAGSSLLAPLLMGHQKAFALLALGHGFTAEAAQKSGIVYQIV
CCHHHHHHCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHCCCEEEEC
DEEALEAEVMKAAEEIAAKPPQAMQIARALMRLPAENIADRITREAKHFAERLTSDEARE
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHH
AVMAFLSRKK
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7751302; 11481430 [H]