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The map label for this gene is fur [C]

Identifier: 23501269

GI number: 23501269

Start: 376166

End: 376624

Strand: Reverse

Name: fur [C]

Synonym: BR0364

Alternate gene names: 23501269

Gene position: 376624-376166 (Counterclockwise)

Preceding gene: 23501272

Following gene: 23501268

Centisome position: 17.87

GC content: 58.82

Gene sequence:

>459_bases
ATGCTGTTCGACCCGCACAAAGCACCCACCAGCCAGCCGAAACCGGCGAAGGTGAAGTCCATCCTTCAGCAGGCCGGGTT
GCGCCCGACACGGCAACGCATGGCACTTGGCCGATTGCTGTTCCTCGATCAAAATCGGCATGTGACACCGGATCTCTTAT
ATGAAGAGGCATTGCAGGCTGGAGTGACCCTTTCGGTCGCCACCGTCTATAACACGCTGAACCAGTTCGCCGAAGCGGGC
CTCGTCCGCAGGATCAGCATTCACGGTGAGCGGACCTATTTCGACACCGACACGGGCGACCACACGCATTTCTATATTGC
CGAGGAAGGGCGCATCATCGACATTCCCTCCGAAAACGTGAGCATCGGTCCCCTGCCCGCCCCGCCAGACGGCTACAGGA
TCAGCAAGGTCGATATCACGATCCAGATCGAGCGGGATCCAGGCTCAAAGCGCATCTGA

Upstream 100 bases:

>100_bases
GGCGCGTCCAGGTGGCAAGCAAGATTGCCATTGTGCCAGAACCGGGCTGTCGAAGACCGCATCTGCGAATGCCGCTTCGC
GCAAGGCAAACGAGGCTGAC

Downstream 100 bases:

>100_bases
TCTAATCTTTTCCCCCACCGCATGATGACAATCGGTCGCAACACAGGGGCGTTCAGCCGCATGGCGCTATCCGCCCCTTC
CTCCTATTTCATGGGCGTCC

Product: FUR family transcriptional regulator

Products: NA

Alternate protein names: Ferric Uptake Regulator Fur Family; Transcriptional Regulator Fur Family; FUR Family Transcriptional Regulator; Ferric-Uptake Regulator; Iron Response Regulator; Fe2+/Zn2+ Uptake Regulation Protein; Ferric Uptake Regulator; Fur Family Ferric Uptake Regulator; Ferric Uptake Regulator FUR Family; Fur Family Transcriptional Regulator; Transcriptional Regulator Fur Family Protein; Helix-Turn-Helix AraC Type; Iron Response Regulator Irr; Transcription Regulator; Transcriptional Regulator; Iron Transcriptional Regulator Protein; Ferric Uptake Transcriptional Regulator

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MLFDPHKAPTSQPKPAKVKSILQQAGLRPTRQRMALGRLLFLDQNRHVTPDLLYEEALQAGVTLSVATVYNTLNQFAEAG
LVRRISIHGERTYFDTDTGDHTHFYIAEEGRIIDIPSENVSIGPLPAPPDGYRISKVDITIQIERDPGSKRI

Sequences:

>Translated_152_residues
MLFDPHKAPTSQPKPAKVKSILQQAGLRPTRQRMALGRLLFLDQNRHVTPDLLYEEALQAGVTLSVATVYNTLNQFAEAG
LVRRISIHGERTYFDTDTGDHTHFYIAEEGRIIDIPSENVSIGPLPAPPDGYRISKVDITIQIERDPGSKRI
>Mature_152_residues
MLFDPHKAPTSQPKPAKVKSILQQAGLRPTRQRMALGRLLFLDQNRHVTPDLLYEEALQAGVTLSVATVYNTLNQFAEAG
LVRRISIHGERTYFDTDTGDHTHFYIAEEGRIIDIPSENVSIGPLPAPPDGYRISKVDITIQIERDPGSKRI

Specific function: Acts As A Global Negative Controlling Element, Employing Fe(2+) As A Cofactor To Bind The Operator Of The Repressed Genes. Regulates The Expression Of Several Outer-Membrane Proteins Including The Iron Transport Operon. [C]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786899, Length=103, Percent_Identity=31.0679611650485, Blast_Score=60, Evalue=7e-11,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 17002; Mature: 17002

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFDPHKAPTSQPKPAKVKSILQQAGLRPTRQRMALGRLLFLDQNRHVTPDLLYEEALQA
CCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHC
GVTLSVATVYNTLNQFAEAGLVRRISIHGERTYFDTDTGDHTHFYIAEEGRIIDIPSENV
CCEEEHHHHHHHHHHHHHCCCEEEEEECCCEEEEECCCCCCEEEEEECCCEEEECCCCCC
SIGPLPAPPDGYRISKVDITIQIERDPGSKRI
EECCCCCCCCCEEEEEEEEEEEEECCCCCCCC
>Mature Secondary Structure
MLFDPHKAPTSQPKPAKVKSILQQAGLRPTRQRMALGRLLFLDQNRHVTPDLLYEEALQA
CCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHC
GVTLSVATVYNTLNQFAEAGLVRRISIHGERTYFDTDTGDHTHFYIAEEGRIIDIPSENV
CCEEEHHHHHHHHHHHHHCCCEEEEEECCCEEEEECCCCCCEEEEEECCCEEEECCCCCC
SIGPLPAPPDGYRISKVDITIQIERDPGSKRI
EECCCCCCCCCEEEEEEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA