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The map label for this gene is kdsB [H]

Identifier: 23500953

GI number: 23500953

Start: 43162

End: 43917

Strand: Reverse

Name: kdsB [H]

Synonym: BR0038

Alternate gene names: 23500953

Gene position: 43917-43162 (Counterclockwise)

Preceding gene: 23500955

Following gene: 23500952

Centisome position: 2.08

GC content: 60.45

Gene sequence:

>756_bases
ATGCTTCAGACAATGAAAACCCTGACGCTCATTCCGACCCGGCTGGGCTCCACCCGCCTGCCGAACAAGCCGCTTGCCGA
TATTTGCGGCAAGCCCATGATCGTGCATGTGGCGGATCGGGCAGCCGCGGCAAAGCTTGGCCGCACGGTGATCGCAACCG
ACAGTGAAGAGATTTTCAAGGTCGTGGCCGCCCACGGCCATGAAGCGATCATGACGCGCGGAGACCATGAATCCGGTTCC
GACCGCATCTATGAAGCACTGGCGAAGCTCGATCCATCGGGCGAAATCGATGCCGTGGTCAATGTGCAGGGCGATCTGCC
AACCATCGATCCCGACACGATCCGCCGCGCGCTCCTGCCGCTGGAGGACGGGCCTGCGGATATCGCAACGCTTGGCGTAG
AGATCACGGTCGAAGAAGAAAAGACCAATCCGAATGTGGTCAAGATCGTCGGCTCCCCGCTGGCGGGCAATAGGCGCCTG
CGCGCGCTTTATTTCACCCGCGCCACCGCGCCTTATGGCGAAGGCCCGCTCTATCATCATATCGGCCTTTACGCCTATCG
CCGTTCTGCCCTTGAACGCTTCGTGAAACTTGGGCCATCGCCGCTGGAAAAGCGCGAGAAGCTGGAGCAGTTGCGCGCAC
TTGAAGCTGGAATGCGCATCGATGTCGAAATCGTGAAGACCGTGCCGCTTGGCGTCGATACGCAGGCCGATCTTGACCGC
GCCCGGACATTTTGCAGCCAGGCGGGAACCATTTGA

Upstream 100 bases:

>100_bases
TGTCGGGACGAGGCGGAAACCGGTTTTCCTGTCGCAAACCTGCGCAAACGGATATATCCACGTATCATTTCCGCCCAAGA
GGCCAAACAAGAGGCACCCC

Downstream 100 bases:

>100_bases
CGCCGCACAAATGCGGCGTAAAAGATTCCTGTAGCACAGGGTAACTGACAGGCCGCCGATGAGCGGCATTTGAGAAAGCA
TGGGTACAATGAAAACCAAC

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MLQTMKTLTLIPTRLGSTRLPNKPLADICGKPMIVHVADRAAAAKLGRTVIATDSEEIFKVVAAHGHEAIMTRGDHESGS
DRIYEALAKLDPSGEIDAVVNVQGDLPTIDPDTIRRALLPLEDGPADIATLGVEITVEEEKTNPNVVKIVGSPLAGNRRL
RALYFTRATAPYGEGPLYHHIGLYAYRRSALERFVKLGPSPLEKREKLEQLRALEAGMRIDVEIVKTVPLGVDTQADLDR
ARTFCSQAGTI

Sequences:

>Translated_251_residues
MLQTMKTLTLIPTRLGSTRLPNKPLADICGKPMIVHVADRAAAAKLGRTVIATDSEEIFKVVAAHGHEAIMTRGDHESGS
DRIYEALAKLDPSGEIDAVVNVQGDLPTIDPDTIRRALLPLEDGPADIATLGVEITVEEEKTNPNVVKIVGSPLAGNRRL
RALYFTRATAPYGEGPLYHHIGLYAYRRSALERFVKLGPSPLEKREKLEQLRALEAGMRIDVEIVKTVPLGVDTQADLDR
ARTFCSQAGTI
>Mature_251_residues
MLQTMKTLTLIPTRLGSTRLPNKPLADICGKPMIVHVADRAAAAKLGRTVIATDSEEIFKVVAAHGHEAIMTRGDHESGS
DRIYEALAKLDPSGEIDAVVNVQGDLPTIDPDTIRRALLPLEDGPADIATLGVEITVEEEKTNPNVVKIVGSPLAGNRRL
RALYFTRATAPYGEGPLYHHIGLYAYRRSALERFVKLGPSPLEKREKLEQLRALEAGMRIDVEIVKTVPLGVDTQADLDR
ARTFCSQAGTI

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=250, Percent_Identity=44, Blast_Score=180, Evalue=8e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 27335; Mature: 27335

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQTMKTLTLIPTRLGSTRLPNKPLADICGKPMIVHVADRAAAAKLGRTVIATDSEEIFK
CCCCHHHHHHHHHHCCCCCCCCCCHHHHCCCCEEEEECCHHHHHHHCCEEEECCHHHHHH
VVAAHGHEAIMTRGDHESGSDRIYEALAKLDPSGEIDAVVNVQGDLPTIDPDTIRRALLP
HHHHCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHCC
LEDGPADIATLGVEITVEEEKTNPNVVKIVGSPLAGNRRLRALYFTRATAPYGEGPLYHH
CCCCCCCEEEEEEEEEEECCCCCCCEEEEECCCCCCCCEEEEEEEEECCCCCCCCCCHHH
IGLYAYRRSALERFVKLGPSPLEKREKLEQLRALEAGMRIDVEIVKTVPLGVDTQADLDR
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHH
ARTFCSQAGTI
HHHHHHHCCCC
>Mature Secondary Structure
MLQTMKTLTLIPTRLGSTRLPNKPLADICGKPMIVHVADRAAAAKLGRTVIATDSEEIFK
CCCCHHHHHHHHHHCCCCCCCCCCHHHHCCCCEEEEECCHHHHHHHCCEEEECCHHHHHH
VVAAHGHEAIMTRGDHESGSDRIYEALAKLDPSGEIDAVVNVQGDLPTIDPDTIRRALLP
HHHHCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHCC
LEDGPADIATLGVEITVEEEKTNPNVVKIVGSPLAGNRRLRALYFTRATAPYGEGPLYHH
CCCCCCCEEEEEEEEEEECCCCCCCEEEEECCCCCCCCEEEEEEEEECCCCCCCCCCHHH
IGLYAYRRSALERFVKLGPSPLEKREKLEQLRALEAGMRIDVEIVKTVPLGVDTQADLDR
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHH
ARTFCSQAGTI
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA