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The map label for this gene is rnpA

Identifier: 23100950

GI number: 23100950

Start: 3629429

End: 3629794

Strand: Reverse

Name: rnpA

Synonym: OB3495

Alternate gene names: 23100950

Gene position: 3629794-3629429 (Counterclockwise)

Preceding gene: 23100951

Following gene: 23100949

Centisome position: 99.98

GC content: 29.78

Gene sequence:

>366_bases
TTGAAAAAACAATATCGTATAAAACAAAATGAAGAATTTCAATATACATTTAAAAAAGGTCATTCATTCGCGAATCGGCA
ATTGGTTATTTACTATCGAGAGAAAGAAGATCAATGCCACTTTCGAATAGGTCTTTCCGTAGGGAAAAAAATCGGTAATG
CCGTAATGAGAAATAGAATTAAACGTTGTTTACGTCAATCTTTTCATGAACTCGAACCGGATATAAAACCAGCCTATGAC
ATTGTTATAATTGCTAGAAATCCTACTAGAAACATGAATTGTGGAGAAATCAAAAAAAGCTTATCTCATCTTTTATATAA
AGAAGGATTACTTAAAAATACAAGAAATAAAACAAGTTTAAGATAG

Upstream 100 bases:

>100_bases
GTTATAGATAGATTTAAGGGGTTACAAACCATATAAATGGTTACATACTAACAAATAAGTACAAGCTTAGGCGGTTGAAT
GTGGGTTAAAGGTGATGACG

Downstream 100 bases:

>100_bases
AATATTGTATGCAATTAGGCTAGAATAACAAGTAAGCAAGGATAGCGTTAAGGAGGAAAAACGTTGCGTAAAAAATTTGG
AATTATAGTCGCTTTAATAG

Product: ribonuclease P

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5

Number of amino acids: Translated: 121; Mature: 121

Protein sequence:

>121_residues
MKKQYRIKQNEEFQYTFKKGHSFANRQLVIYYREKEDQCHFRIGLSVGKKIGNAVMRNRIKRCLRQSFHELEPDIKPAYD
IVIIARNPTRNMNCGEIKKSLSHLLYKEGLLKNTRNKTSLR

Sequences:

>Translated_121_residues
MKKQYRIKQNEEFQYTFKKGHSFANRQLVIYYREKEDQCHFRIGLSVGKKIGNAVMRNRIKRCLRQSFHELEPDIKPAYD
IVIIARNPTRNMNCGEIKKSLSHLLYKEGLLKNTRNKTSLR
>Mature_121_residues
MKKQYRIKQNEEFQYTFKKGHSFANRQLVIYYREKEDQCHFRIGLSVGKKIGNAVMRNRIKRCLRQSFHELEPDIKPAYD
IVIIARNPTRNMNCGEIKKSLSHLLYKEGLLKNTRNKTSLR

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: COG0594

COG function: function code J; RNase P protein component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNPA_OCEIH (Q8EKU0)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_694417.1
- ProteinModelPortal:   Q8EKU0
- SMR:   Q8EKU0
- GeneID:   1016166
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB3495
- NMPDR:   fig|221109.1.peg.3499
- HOGENOM:   HBG728160
- OMA:   KIGNAVM
- ProtClustDB:   PRK00499
- BioCyc:   OIHE221109:OB3495-MONOMER
- BRENDA:   3.1.26.5
- HAMAP:   MF_00227
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- InterPro:   IPR020539
- Gene3D:   G3DSA:3.30.230.10
- ProDom:   PD003629
- TIGRFAMs:   TIGR00188

Pfam domain/function: PF00825 Ribonuclease_P; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =3.1.26.5

Molecular weight: Translated: 14460; Mature: 14460

Theoretical pI: Translated: 10.74; Mature: 10.74

Prosite motif: PS00648 RIBONUCLEASE_P

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQYRIKQNEEFQYTFKKGHSFANRQLVIYYREKEDQCHFRIGLSVGKKIGNAVMRNRI
CCCCCCCCCCCCEEEHHHCCCCCCCCEEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHH
KRCLRQSFHELEPDIKPAYDIVIIARNPTRNMNCGEIKKSLSHLLYKEGLLKNTRNKTSL
HHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
R
C
>Mature Secondary Structure
MKKQYRIKQNEEFQYTFKKGHSFANRQLVIYYREKEDQCHFRIGLSVGKKIGNAVMRNRI
CCCCCCCCCCCCEEEHHHCCCCCCCCEEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHH
KRCLRQSFHELEPDIKPAYDIVIIARNPTRNMNCGEIKKSLSHLLYKEGLLKNTRNKTSL
HHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376