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The map label for this gene is fabG [H]

Identifier: 23100930

GI number: 23100930

Start: 3611218

End: 3611973

Strand: Reverse

Name: fabG [H]

Synonym: OB3475

Alternate gene names: 23100930

Gene position: 3611973-3611218 (Counterclockwise)

Preceding gene: 23100931

Following gene: 23100929

Centisome position: 99.49

GC content: 38.49

Gene sequence:

>756_bases
ATGAAAATTACCAAACAAATAGCAGTTGTTACAGGAGTAAGTCATGGAGATGGTATTGGGGCTGCGACATGTAGAAAGTT
GGCTGAACAAGGTAATTCCATCTTTTTTACGCATTATCAATCGGAAGATGATTGGGTTCATGCGTTTCAAGAAGAAATAA
AATATAAAGGTGTTGCGTGCGAGTCGATGGAAGTTGACTTATCGGAAATACATTCCTATAAAAATATATTGAATACGGTC
ACCAGTAAAATTGGAATGCCGTCTATTCTAGTCAATAATGCGGCACATTCTACTCGAGATGGTTATAAAAAACTTACACC
AGAGATTATTGATAAACACTATCAAGTCAATATGCGCCAAACGATGATGTTAAGTGTAGCATTTGCACGCCAATTCAAGC
CGGAGGATCCTAACCAAAAAGGAAGAATTATTAACCTGACATCTGGTCAATTTCAAGGTCCAATGATCGATGAACTTGCA
TACGTAGCTACAAAAGGGGCTATATCAGCATTTACATTGTCACTATCGGCAGAAGTTGCCCACTTAGGTATTACAGTTAA
TGCAGTAAACCCTGGTCCTACCGATACAGGATGGATGAACGGAGAATTAAAAAAAGAATTGGAATCAAAATTTTTATCCG
GAAGAGTTGGGCAACCAATGGATGCAGCAAAATTAATCGCATTTTTAGCTGGTGAAGACGCAGCGTGGATCACAGGGCAG
GTAATTAATTCAGAAGGTGCTTTTTTGAGGAAATAA

Upstream 100 bases:

>100_bases
TATATCCGCAGAGATGATAATCGCAAAAATTCGTGGAGAGAAGGTAGAAAGTCGTTTATTAGAACATGAATTAATTATTC
GAGAGTCTACATAGGAGGAG

Downstream 100 bases:

>100_bases
TCTTAAAATTTAAAAATCATGTTGACAAGTTCAAGAGAAACGTTATAATAAACTAAAATGTAAACGATTTCATTTTACAA
ACTATTTTGTACAATGGAGT

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MKITKQIAVVTGVSHGDGIGAATCRKLAEQGNSIFFTHYQSEDDWVHAFQEEIKYKGVACESMEVDLSEIHSYKNILNTV
TSKIGMPSILVNNAAHSTRDGYKKLTPEIIDKHYQVNMRQTMMLSVAFARQFKPEDPNQKGRIINLTSGQFQGPMIDELA
YVATKGAISAFTLSLSAEVAHLGITVNAVNPGPTDTGWMNGELKKELESKFLSGRVGQPMDAAKLIAFLAGEDAAWITGQ
VINSEGAFLRK

Sequences:

>Translated_251_residues
MKITKQIAVVTGVSHGDGIGAATCRKLAEQGNSIFFTHYQSEDDWVHAFQEEIKYKGVACESMEVDLSEIHSYKNILNTV
TSKIGMPSILVNNAAHSTRDGYKKLTPEIIDKHYQVNMRQTMMLSVAFARQFKPEDPNQKGRIINLTSGQFQGPMIDELA
YVATKGAISAFTLSLSAEVAHLGITVNAVNPGPTDTGWMNGELKKELESKFLSGRVGQPMDAAKLIAFLAGEDAAWITGQ
VINSEGAFLRK
>Mature_251_residues
MKITKQIAVVTGVSHGDGIGAATCRKLAEQGNSIFFTHYQSEDDWVHAFQEEIKYKGVACESMEVDLSEIHSYKNILNTV
TSKIGMPSILVNNAAHSTRDGYKKLTPEIIDKHYQVNMRQTMMLSVAFARQFKPEDPNQKGRIINLTSGQFQGPMIDELA
YVATKGAISAFTLSLSAEVAHLGITVNAVNPGPTDTGWMNGELKKELESKFLSGRVGQPMDAAKLIAFLAGEDAAWITGQ
VINSEGAFLRK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=26.5060240963855, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI15277342, Length=263, Percent_Identity=25.4752851711027, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI7705925, Length=245, Percent_Identity=26.1224489795918, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI5031737, Length=250, Percent_Identity=25.2, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1788459, Length=248, Percent_Identity=30.241935483871, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI2367365, Length=236, Percent_Identity=31.7796610169492, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787335, Length=253, Percent_Identity=29.6442687747036, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=27.2373540856031, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1789208, Length=252, Percent_Identity=27.7777777777778, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI2367175, Length=249, Percent_Identity=29.3172690763052, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI87082160, Length=257, Percent_Identity=26.0700389105058, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787905, Length=253, Percent_Identity=26.4822134387352, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=28.2868525896414, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=267, Percent_Identity=28.8389513108614, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI193204405, Length=268, Percent_Identity=29.4776119402985, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=266, Percent_Identity=28.1954887218045, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=268, Percent_Identity=28.7313432835821, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17531453, Length=269, Percent_Identity=29.7397769516729, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=27.6515151515151, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=269, Percent_Identity=28.996282527881, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=26.8939393939394, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=256, Percent_Identity=26.171875, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=27.3408239700375, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=27.1317829457364, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17536025, Length=251, Percent_Identity=24.7011952191235, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI25147288, Length=248, Percent_Identity=29.0322580645161, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17561272, Length=199, Percent_Identity=25.1256281407035, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=25.0950570342205, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=268, Percent_Identity=24.6268656716418, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=252, Percent_Identity=25.7936507936508, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=259, Percent_Identity=27.4131274131274, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=198, Percent_Identity=27.2727272727273, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=26.5060240963855, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71994604, Length=261, Percent_Identity=28.3524904214559, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=256, Percent_Identity=26.171875, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=266, Percent_Identity=25.187969924812, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=268, Percent_Identity=26.4925373134328, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=25.4681647940075, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=269, Percent_Identity=25.2788104089219, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=32.6612903225806, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI23397609, Length=256, Percent_Identity=28.125, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21355319, Length=253, Percent_Identity=28.4584980237154, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=28.5714285714286, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI21357041, Length=244, Percent_Identity=30.327868852459, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24644339, Length=265, Percent_Identity=28.6792452830189, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24643142, Length=248, Percent_Identity=23.7903225806452, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100

Molecular weight: Translated: 27453; Mature: 27453

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITKQIAVVTGVSHGDGIGAATCRKLAEQGNSIFFTHYQSEDDWVHAFQEEIKYKGVAC
CCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHCCCEE
ESMEVDLSEIHSYKNILNTVTSKIGMPSILVNNAAHSTRDGYKKLTPEIIDKHYQVNMRQ
CCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHCCHHHHHHHHCCCHHH
TMMLSVAFARQFKPEDPNQKGRIINLTSGQFQGPMIDELAYVATKGAISAFTLSLSAEVA
HHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEEEECEEE
HLGITVNAVNPGPTDTGWMNGELKKELESKFLSGRVGQPMDAAKLIAFLAGEDAAWITGQ
EEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEEEEE
VINSEGAFLRK
EECCCCCCCCC
>Mature Secondary Structure
MKITKQIAVVTGVSHGDGIGAATCRKLAEQGNSIFFTHYQSEDDWVHAFQEEIKYKGVAC
CCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHCCCEE
ESMEVDLSEIHSYKNILNTVTSKIGMPSILVNNAAHSTRDGYKKLTPEIIDKHYQVNMRQ
CCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHCCHHHHHHHHCCCHHH
TMMLSVAFARQFKPEDPNQKGRIINLTSGQFQGPMIDELAYVATKGAISAFTLSLSAEVA
HHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEEEECEEE
HLGITVNAVNPGPTDTGWMNGELKKELESKFLSGRVGQPMDAAKLIAFLAGEDAAWITGQ
EEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEEEEE
VINSEGAFLRK
EECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]