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The map label for this gene is gntK [H]

Identifier: 23100644

GI number: 23100644

Start: 3319158

End: 3320711

Strand: Reverse

Name: gntK [H]

Synonym: OB3189

Alternate gene names: 23100644

Gene position: 3320711-3319158 (Counterclockwise)

Preceding gene: 23100645

Following gene: 23100643

Centisome position: 91.47

GC content: 38.48

Gene sequence:

>1554_bases
TTGAATCAAAATAAGTATATGCTTGGTGTCGATATCGGCACAACAAGTACAAAAGCAGTATTATACCGGGAAACGGGCGA
AATCATTGCTCAAGGAAATCACGGATATGATTTATATACTCCGGATGTATCCACTGCAGAGCAAGATCCAGAAGAAATAT
ATTTAGCGGTACGCTTGACGATAAAGCGGGTAATGGAAGAATCCGCTATTGATAAAGAAGATCTATCCTTTATTTCTTTC
AGTAGTGCGATGCATAGTTTAATTGCCATAGATGAACAACATCAAGCGATTACTCCATGTATTACATGGGCAGATAATCG
AAGTGCTGGTTGGGCGAAGAAAATTAAACAGGAAATGAATGGGCATGAAATATATCGTAAAACTGGTACACCTATTCATC
CGATGTCTCCATTAAGTAAAATTACATGGATTCAAAATGAACGACCAGAGATAGCGGAAAAGGCGAAAAAATACATTGGT
ATTAAGGAATATGTTTTTTATCAATTATTCGGGGAGTATGTCGTTGACCATTCTATCGCTTCTGCAACAGGAATGATGAA
TTTAGAAGAATTATCGTGGGATGAAGAAGCACTTCAGGTAGCAGGAATAAATAAAGATCAATTATCTTCATTAGTTCCGA
CCACGAAAATCTTAACAGGTTGTGACGAAACAGTTGCTAAAGAGATGGGAATCACAAGCAATACGAAATTTATCATTGGC
GCAAGTGATGGTGTACTATCCAATATCGGTGTAAACGCTATTAAAGACGGGGAAGTTGCAATAACTATTGGTACCAGTGG
TGCAATTCGTACCGTGATCCCAAAACCTAGAACGGATCAAAAAGGCCGTATTTTTTGCTATGCATTAACAGAAGATCATT
GGGTGATTGGTGGACCAGTCAATAACGGGGGGATGGTTCTTCGTTGGATTCGAGATGAGCTGGCTGCAAGTGAAGTAGAA
ACAGCTAAACGTTTAAACGTCGATCCATATGAAGTTTTAACTACCATTGCTAGTAAAGTAAGCCCAGGTTCCAATGGGTT
ATTATTCCATCCATTCCTAGCTGGAGAACGTGCCCCACTATGGAATTCGGACGTGCGTGGTTCCTTTATTGGATTAACCT
TAAATCATAAAAAGGAACATATGGTACGAGCAGCTTTAGAAGGTGTTATTTTTAACTTGTATTCTGTATTCCTTGCTTTA
GTAGAAGTAATGGATGTTCCAGTCAAATCTATTAAAGCAACAGGCGGATTTTCTAGATCGGAATTATGGCGACAGATGAT
GGCAGATATCTTTGATCAAGATGTAATTGTGCCAAAAAGCTATGAATCTTCATGTCTAGGTGCATGCATGCTTGGACTAT
ATGCCGAAGAAAAAATCGATTCATTTGATGTAGTGGAAGATTTAATTGGACATACACATGCACACGAACCGAATGAAGCA
AATGTAGAAGCTTATCGAGAACTGATGCCAATCTTTATTCGCATTGCACGTGCACTCGAAAGTGAATATGAACAGATAGC
GGTTTATCAACAGAAATCCATAGATAATAAATAA

Upstream 100 bases:

>100_bases
TTGGTGAATAATGCATTTTATAAAAACTTTAATGATGTCCAAAATCGTGTAGAACGTCTCTGGAGTGACGATGAGCGAAT
GAAGATTGTGAGGGAGAGCA

Downstream 100 bases:

>100_bases
TAACATCAAGATGGGAGCGAGAACTTGTGGATAATATAATGCCATTAATTATTGTAGCATTAGCTGTAGTATTACTATTG
CTACTCATAATGAAATGGAA

Product: gluconokinase

Products: NA

Alternate protein names: Gluconate kinase [H]

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MNQNKYMLGVDIGTTSTKAVLYRETGEIIAQGNHGYDLYTPDVSTAEQDPEEIYLAVRLTIKRVMEESAIDKEDLSFISF
SSAMHSLIAIDEQHQAITPCITWADNRSAGWAKKIKQEMNGHEIYRKTGTPIHPMSPLSKITWIQNERPEIAEKAKKYIG
IKEYVFYQLFGEYVVDHSIASATGMMNLEELSWDEEALQVAGINKDQLSSLVPTTKILTGCDETVAKEMGITSNTKFIIG
ASDGVLSNIGVNAIKDGEVAITIGTSGAIRTVIPKPRTDQKGRIFCYALTEDHWVIGGPVNNGGMVLRWIRDELAASEVE
TAKRLNVDPYEVLTTIASKVSPGSNGLLFHPFLAGERAPLWNSDVRGSFIGLTLNHKKEHMVRAALEGVIFNLYSVFLAL
VEVMDVPVKSIKATGGFSRSELWRQMMADIFDQDVIVPKSYESSCLGACMLGLYAEEKIDSFDVVEDLIGHTHAHEPNEA
NVEAYRELMPIFIRIARALESEYEQIAVYQQKSIDNK

Sequences:

>Translated_517_residues
MNQNKYMLGVDIGTTSTKAVLYRETGEIIAQGNHGYDLYTPDVSTAEQDPEEIYLAVRLTIKRVMEESAIDKEDLSFISF
SSAMHSLIAIDEQHQAITPCITWADNRSAGWAKKIKQEMNGHEIYRKTGTPIHPMSPLSKITWIQNERPEIAEKAKKYIG
IKEYVFYQLFGEYVVDHSIASATGMMNLEELSWDEEALQVAGINKDQLSSLVPTTKILTGCDETVAKEMGITSNTKFIIG
ASDGVLSNIGVNAIKDGEVAITIGTSGAIRTVIPKPRTDQKGRIFCYALTEDHWVIGGPVNNGGMVLRWIRDELAASEVE
TAKRLNVDPYEVLTTIASKVSPGSNGLLFHPFLAGERAPLWNSDVRGSFIGLTLNHKKEHMVRAALEGVIFNLYSVFLAL
VEVMDVPVKSIKATGGFSRSELWRQMMADIFDQDVIVPKSYESSCLGACMLGLYAEEKIDSFDVVEDLIGHTHAHEPNEA
NVEAYRELMPIFIRIARALESEYEQIAVYQQKSIDNK
>Mature_517_residues
MNQNKYMLGVDIGTTSTKAVLYRETGEIIAQGNHGYDLYTPDVSTAEQDPEEIYLAVRLTIKRVMEESAIDKEDLSFISF
SSAMHSLIAIDEQHQAITPCITWADNRSAGWAKKIKQEMNGHEIYRKTGTPIHPMSPLSKITWIQNERPEIAEKAKKYIG
IKEYVFYQLFGEYVVDHSIASATGMMNLEELSWDEEALQVAGINKDQLSSLVPTTKILTGCDETVAKEMGITSNTKFIIG
ASDGVLSNIGVNAIKDGEVAITIGTSGAIRTVIPKPRTDQKGRIFCYALTEDHWVIGGPVNNGGMVLRWIRDELAASEVE
TAKRLNVDPYEVLTTIASKVSPGSNGLLFHPFLAGERAPLWNSDVRGSFIGLTLNHKKEHMVRAALEGVIFNLYSVFLAL
VEVMDVPVKSIKATGGFSRSELWRQMMADIFDQDVIVPKSYESSCLGACMLGLYAEEKIDSFDVVEDLIGHTHAHEPNEA
NVEAYRELMPIFIRIARALESEYEQIAVYQQKSIDNK

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI41393575, Length=454, Percent_Identity=24.2290748898678, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI189409120, Length=472, Percent_Identity=23.5169491525424, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI4504007, Length=472, Percent_Identity=23.5169491525424, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI42794763, Length=457, Percent_Identity=23.4135667396061, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI88196792, Length=480, Percent_Identity=21.25, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI164663828, Length=497, Percent_Identity=23.5412474849095, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI18860918, Length=419, Percent_Identity=21.2410501193317, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI164663830, Length=525, Percent_Identity=22.0952380952381, Blast_Score=76, Evalue=8e-14,
Organism=Escherichia coli, GI1789987, Length=497, Percent_Identity=25.9557344064386, Blast_Score=169, Evalue=6e-43,
Organism=Escherichia coli, GI1787789, Length=498, Percent_Identity=25.9036144578313, Blast_Score=153, Evalue=3e-38,
Organism=Escherichia coli, GI1790361, Length=464, Percent_Identity=24.3534482758621, Blast_Score=129, Evalue=6e-31,
Organism=Escherichia coli, GI1789168, Length=471, Percent_Identity=21.2314225053079, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1790005, Length=498, Percent_Identity=22.6907630522088, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789138, Length=504, Percent_Identity=22.8174603174603, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1790338, Length=213, Percent_Identity=23.943661971831, Blast_Score=69, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17535599, Length=474, Percent_Identity=24.4725738396624, Blast_Score=113, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6321755, Length=432, Percent_Identity=26.6203703703704, Blast_Score=103, Evalue=9e-23,
Organism=Drosophila melanogaster, GI17864214, Length=478, Percent_Identity=24.0585774058577, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24654573, Length=407, Percent_Identity=24.3243243243243, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24655555, Length=441, Percent_Identity=24.2630385487528, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24655560, Length=441, Percent_Identity=24.2630385487528, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24655570, Length=441, Percent_Identity=24.2630385487528, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24655574, Length=441, Percent_Identity=24.2630385487528, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24655565, Length=441, Percent_Identity=24.2630385487528, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24656367, Length=487, Percent_Identity=22.7926078028747, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI21357867, Length=509, Percent_Identity=22.3968565815324, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24657106, Length=556, Percent_Identity=21.5827338129496, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24657102, Length=556, Percent_Identity=21.5827338129496, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24656372, Length=304, Percent_Identity=26.6447368421053, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006002 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 57494; Mature: 57494

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQNKYMLGVDIGTTSTKAVLYRETGEIIAQGNHGYDLYTPDVSTAEQDPEEIYLAVRLT
CCCCCEEEEEEECCCCCEEEEEEECCCEEEECCCCCEEECCCCCCCCCCHHHEEHHHHHH
IKRVMEESAIDKEDLSFISFSSAMHSLIAIDEQHQAITPCITWADNRSAGWAKKIKQEMN
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEECCEEEECCCCCCHHHHHHHHHCC
GHEIYRKTGTPIHPMSPLSKITWIQNERPEIAEKAKKYIGIKEYVFYQLFGEYVVDHSIA
CHHHHHCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
SATGMMNLEELSWDEEALQVAGINKDQLSSLVPTTKILTGCDETVAKEMGITSNTKFIIG
HHHCCCCHHHCCCCHHHHHCCCCCHHHHHHHCCHHHHHHCCHHHHHHHCCCCCCCEEEEE
ASDGVLSNIGVNAIKDGEVAITIGTSGAIRTVIPKPRTDQKGRIFCYALTEDHWVIGGPV
CCCCCHHHCCCCEEECCCEEEEEECCCCEEEECCCCCCCCCCCEEEEEECCCCEEEECCC
NNGGMVLRWIRDELAASEVETAKRLNVDPYEVLTTIASKVSPGSNGLLFHPFLAGERAPL
CCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCC
WNSDVRGSFIGLTLNHKKEHMVRAALEGVIFNLYSVFLALVEVMDVPVKSIKATGGFSRS
CCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHH
ELWRQMMADIFDQDVIVPKSYESSCLGACMLGLYAEEKIDSFDVVEDLIGHTHAHEPNEA
HHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCC
NVEAYRELMPIFIRIARALESEYEQIAVYQQKSIDNK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNQNKYMLGVDIGTTSTKAVLYRETGEIIAQGNHGYDLYTPDVSTAEQDPEEIYLAVRLT
CCCCCEEEEEEECCCCCEEEEEEECCCEEEECCCCCEEECCCCCCCCCCHHHEEHHHHHH
IKRVMEESAIDKEDLSFISFSSAMHSLIAIDEQHQAITPCITWADNRSAGWAKKIKQEMN
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEECCEEEECCCCCCHHHHHHHHHCC
GHEIYRKTGTPIHPMSPLSKITWIQNERPEIAEKAKKYIGIKEYVFYQLFGEYVVDHSIA
CHHHHHCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
SATGMMNLEELSWDEEALQVAGINKDQLSSLVPTTKILTGCDETVAKEMGITSNTKFIIG
HHHCCCCHHHCCCCHHHHHCCCCCHHHHHHHCCHHHHHHCCHHHHHHHCCCCCCCEEEEE
ASDGVLSNIGVNAIKDGEVAITIGTSGAIRTVIPKPRTDQKGRIFCYALTEDHWVIGGPV
CCCCCHHHCCCCEEECCCEEEEEECCCCEEEECCCCCCCCCCCEEEEEECCCCEEEECCC
NNGGMVLRWIRDELAASEVETAKRLNVDPYEVLTTIASKVSPGSNGLLFHPFLAGERAPL
CCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCC
WNSDVRGSFIGLTLNHKKEHMVRAALEGVIFNLYSVFLALVEVMDVPVKSIKATGGFSRS
CCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHH
ELWRQMMADIFDQDVIVPKSYESSCLGACMLGLYAEEKIDSFDVVEDLIGHTHAHEPNEA
HHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCC
NVEAYRELMPIFIRIARALESEYEQIAVYQQKSIDNK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3020045; 7584049; 9384377 [H]