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The map label for this gene is htpG

Identifier: 23100613

GI number: 23100613

Start: 3288835

End: 3290712

Strand: Reverse

Name: htpG

Synonym: OB3158

Alternate gene names: 23100613

Gene position: 3290712-3288835 (Counterclockwise)

Preceding gene: 23100615

Following gene: 23100608

Centisome position: 90.64

GC content: 33.97

Gene sequence:

>1878_bases
ATGGGAAAGCGTAAATTTAAAGCCGAGTCACAAAAACTATTAGATATGGTGATTAACTCTATTTATTCACAGCGCGAAGT
GTTCTTGCGTGAATTGATTTCCAATGCAAGTGATGCGATAGATAAGATTTACTATAAAGCATTAACCGATGATTCCCTGT
CATTTGATGTGGACAACTATTATATAAAAATTACTCCAAATAAAGAGGAACGCACATTAACGGTTGTCGATACAGGGATC
GGTATGACAAAAGAAGAATTAGAAAATAATCTTGGTGTGATCGCAAAAAGTGGTTCTCATACATTTAAATCAGAGAATGA
AATTAAAGATGGCCATGATATCATAGGACAATTCGGGGTTGGTTTCTATGCTGCGTTTATGGTAGCGGATAAAGTAGAAG
TGGTAACGAAATCTATTGATAGTGATGCAGCATTTAAATGGGAATCCAAAGGGTCTGATGGATATTCTATTACAGAAGCG
GATAAGCAAGATATTGGAACAACAATTACATTGTATATTAAAGAAAATCAAGAAGAAGAAAACTATGATGAGTTCTTAGA
TACATTTACGTTACAGCAAATCATTAAAAAGTACTCTGATTTTATCCGTTACCCAATTAAAATGGACGTAACGGAAAGTA
AGTTGAAAGAAGGGTCAGAAGACGAATATGAAGATGTAGTAGAGGAACAAACAATTAATACGATGGTTCCTATCTGGAAG
AAGAATAAGAGCGAATTAACCGATGATGACTATACGAATTTCTACCAGGAAAAACGCTATGGATTTGATAAACCACTCAA
ACATGTACACATTAATGTGGATGGTTCCATTCGTTATAATGCTATATTATTTATCCCAGAAAGTGCGCCATTTAATTACT
ATACACGTGATTATGAAAAGGGTCTTGAGCTTTATTCGAACGGTGTATTAATTATGGATAAGTGTGCGGACTTACTTCCG
GATTACTTTAGTTTTGTTAAAGGAATGGTAGACTCGGAAGATCTTTCACTTAACATCTCCCGTGAAATGCTACAACATGA
TCGCCAATTAAAGCTAATCGCTAAAAATATTAAGAAAAAAGTGAAACAGCAGCTAGTAAGTCTTTTACGTGACGAACGTG
AAAACTATGAAAAATTCTTTGATGCATTCGGTCAACAAATTAAATTTGGTGTGTACAGTGATTACGGTCAAAACAAAGAT
GAGCTGAAAGATTTACTTCTATTTTATTCTTCTAAAGAGAAGAAATTAGTAACCCTTGAGGAATATGTTTCATGTATGCC
AGAGGATCAAAAGTATATCTATTATGCTACAGGAGATTCAAGAGATCGAATTGAAAAGCTTCCACAAACAGAATTAGTTG
CTGATAAAGGCTATGAAATTCTTTATTTCACAGATGAAATCGATGAATTCGCCATTAAAATGCTTATGAACTATGATGAA
AAAGAATTCCGTTCCGTATCAAGTGGTGATTTAGGCATTGAAGAAGACGAAAAAGAAGAAAATGAACAAGAAAACAACGA
TAATGCAGAATTATTTACAGCGATGAAAGAAGTATTGTCTACCAAAGTAAAAGATGTACGTGCTTCGAAGCGCTTAAAAT
CACATCCAGTCGTGTTGACTGCAGATGGTGAAATCTCCCTTGAAATGGAGAAAATCATTAATGCAATGCCAGATGATCAG
CAAATCCAAGCTGATAAAGTATTGGAGATTAATGTAAATCACGATATTTTCCAATCTTTAAAAGCAGCGCAAGGTAATGA
TGATGAGAAGTTCAAACTATATACTAACCTGTTATATAATCAAGCACTTCTTATTGAAGGATTACCAATTAATGATCCAG
TAGAATTTACAAATGACATTTGTAAAGTAATGGTATAG

Upstream 100 bases:

>100_bases
CAACGATATTGACAGAAAAATGGGGATATGTTATTAAAAATATAGAGGTTAGCACTCGTAAGTAGTGAGTGCTAAATGTA
GAAAAGAAGGAGATGTTATT

Downstream 100 bases:

>100_bases
GTTGTCTAAGACATGTGCTTCGGCAGTTAAAGAATCGCTCGCGAGGAAAATGTTGAACTTTCCTCCGGGCGATTTTACTT
TGAAAGTTTCTATAGCTCAT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 625; Mature: 624

Protein sequence:

>625_residues
MGKRKFKAESQKLLDMVINSIYSQREVFLRELISNASDAIDKIYYKALTDDSLSFDVDNYYIKITPNKEERTLTVVDTGI
GMTKEELENNLGVIAKSGSHTFKSENEIKDGHDIIGQFGVGFYAAFMVADKVEVVTKSIDSDAAFKWESKGSDGYSITEA
DKQDIGTTITLYIKENQEEENYDEFLDTFTLQQIIKKYSDFIRYPIKMDVTESKLKEGSEDEYEDVVEEQTINTMVPIWK
KNKSELTDDDYTNFYQEKRYGFDKPLKHVHINVDGSIRYNAILFIPESAPFNYYTRDYEKGLELYSNGVLIMDKCADLLP
DYFSFVKGMVDSEDLSLNISREMLQHDRQLKLIAKNIKKKVKQQLVSLLRDERENYEKFFDAFGQQIKFGVYSDYGQNKD
ELKDLLLFYSSKEKKLVTLEEYVSCMPEDQKYIYYATGDSRDRIEKLPQTELVADKGYEILYFTDEIDEFAIKMLMNYDE
KEFRSVSSGDLGIEEDEKEENEQENNDNAELFTAMKEVLSTKVKDVRASKRLKSHPVVLTADGEISLEMEKIINAMPDDQ
QIQADKVLEINVNHDIFQSLKAAQGNDDEKFKLYTNLLYNQALLIEGLPINDPVEFTNDICKVMV

Sequences:

>Translated_625_residues
MGKRKFKAESQKLLDMVINSIYSQREVFLRELISNASDAIDKIYYKALTDDSLSFDVDNYYIKITPNKEERTLTVVDTGI
GMTKEELENNLGVIAKSGSHTFKSENEIKDGHDIIGQFGVGFYAAFMVADKVEVVTKSIDSDAAFKWESKGSDGYSITEA
DKQDIGTTITLYIKENQEEENYDEFLDTFTLQQIIKKYSDFIRYPIKMDVTESKLKEGSEDEYEDVVEEQTINTMVPIWK
KNKSELTDDDYTNFYQEKRYGFDKPLKHVHINVDGSIRYNAILFIPESAPFNYYTRDYEKGLELYSNGVLIMDKCADLLP
DYFSFVKGMVDSEDLSLNISREMLQHDRQLKLIAKNIKKKVKQQLVSLLRDERENYEKFFDAFGQQIKFGVYSDYGQNKD
ELKDLLLFYSSKEKKLVTLEEYVSCMPEDQKYIYYATGDSRDRIEKLPQTELVADKGYEILYFTDEIDEFAIKMLMNYDE
KEFRSVSSGDLGIEEDEKEENEQENNDNAELFTAMKEVLSTKVKDVRASKRLKSHPVVLTADGEISLEMEKIINAMPDDQ
QIQADKVLEINVNHDIFQSLKAAQGNDDEKFKLYTNLLYNQALLIEGLPINDPVEFTNDICKVMV
>Mature_624_residues
GKRKFKAESQKLLDMVINSIYSQREVFLRELISNASDAIDKIYYKALTDDSLSFDVDNYYIKITPNKEERTLTVVDTGIG
MTKEELENNLGVIAKSGSHTFKSENEIKDGHDIIGQFGVGFYAAFMVADKVEVVTKSIDSDAAFKWESKGSDGYSITEAD
KQDIGTTITLYIKENQEEENYDEFLDTFTLQQIIKKYSDFIRYPIKMDVTESKLKEGSEDEYEDVVEEQTINTMVPIWKK
NKSELTDDDYTNFYQEKRYGFDKPLKHVHINVDGSIRYNAILFIPESAPFNYYTRDYEKGLELYSNGVLIMDKCADLLPD
YFSFVKGMVDSEDLSLNISREMLQHDRQLKLIAKNIKKKVKQQLVSLLRDERENYEKFFDAFGQQIKFGVYSDYGQNKDE
LKDLLLFYSSKEKKLVTLEEYVSCMPEDQKYIYYATGDSRDRIEKLPQTELVADKGYEILYFTDEIDEFAIKMLMNYDEK
EFRSVSSGDLGIEEDEKEENEQENNDNAELFTAMKEVLSTKVKDVRASKRLKSHPVVLTADGEISLEMEKIINAMPDDQQ
IQADKVLEINVNHDIFQSLKAAQGNDDEKFKLYTNLLYNQALLIEGLPINDPVEFTNDICKVMV

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI20149594, Length=678, Percent_Identity=37.905604719764, Blast_Score=399, Evalue=1e-111,
Organism=Homo sapiens, GI154146191, Length=681, Percent_Identity=36.8575624082232, Blast_Score=397, Evalue=1e-110,
Organism=Homo sapiens, GI153792590, Length=681, Percent_Identity=36.8575624082232, Blast_Score=396, Evalue=1e-110,
Organism=Homo sapiens, GI4507677, Length=677, Percent_Identity=34.1211225997046, Blast_Score=331, Evalue=1e-90,
Organism=Homo sapiens, GI155722983, Length=646, Percent_Identity=31.1145510835913, Blast_Score=321, Evalue=1e-87,
Organism=Escherichia coli, GI1786679, Length=635, Percent_Identity=38.1102362204724, Blast_Score=418, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI17559162, Length=663, Percent_Identity=38.1598793363499, Blast_Score=409, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI17542208, Length=672, Percent_Identity=34.5238095238095, Blast_Score=336, Evalue=2e-92,
Organism=Caenorhabditis elegans, GI115535205, Length=653, Percent_Identity=32.1592649310873, Blast_Score=295, Evalue=4e-80,
Organism=Caenorhabditis elegans, GI115535167, Length=435, Percent_Identity=36.0919540229885, Blast_Score=240, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6325016, Length=676, Percent_Identity=36.8343195266272, Blast_Score=395, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6323840, Length=672, Percent_Identity=36.6071428571429, Blast_Score=394, Evalue=1e-110,
Organism=Drosophila melanogaster, GI17647529, Length=668, Percent_Identity=38.3233532934132, Blast_Score=413, Evalue=1e-115,
Organism=Drosophila melanogaster, GI21357739, Length=675, Percent_Identity=35.1111111111111, Blast_Score=350, Evalue=2e-96,
Organism=Drosophila melanogaster, GI24586016, Length=645, Percent_Identity=32.7131782945736, Blast_Score=305, Evalue=8e-83,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_OCEIH (Q8CX68)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_694080.1
- ProteinModelPortal:   Q8CX68
- GeneID:   1016581
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB3158
- NMPDR:   fig|221109.1.peg.3161
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- ProtClustDB:   PRK05218
- BioCyc:   OIHE221109:OB3158-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 72320; Mature: 72189

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKRKFKAESQKLLDMVINSIYSQREVFLRELISNASDAIDKIYYKALTDDSLSFDVDNY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCE
YIKITPNKEERTLTVVDTGIGMTKEELENNLGVIAKSGSHTFKSENEIKDGHDIIGQFGV
EEEEECCCCCCEEEEEECCCCCCHHHHHCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHH
GFYAAFMVADKVEVVTKSIDSDAAFKWESKGSDGYSITEADKQDIGTTITLYIKENQEEE
HHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCEECCCCHHHCCCEEEEEEECCCCCC
NYDEFLDTFTLQQIIKKYSDFIRYPIKMDVTESKLKEGSEDEYEDVVEEQTINTMVPIWK
CHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
KNKSELTDDDYTNFYQEKRYGFDKPLKHVHINVDGSIRYNAILFIPESAPFNYYTRDYEK
CCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCEEEEEEEEEECCCCCCCHHHHHHH
GLELYSNGVLIMDKCADLLPDYFSFVKGMVDSEDLSLNISREMLQHDRQLKLIAKNIKKK
HHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHCCHHHHHHHHHHHHH
VKQQLVSLLRDERENYEKFFDAFGQQIKFGVYSDYGQNKDELKDLLLFYSSKEKKLVTLE
HHHHHHHHHHHHHHHHHHHHHHHHHHEEECEECCCCCCHHHHHHHHHHHCCCCCEEEEHH
EYVSCMPEDQKYIYYATGDSRDRIEKLPQTELVADKGYEILYFTDEIDEFAIKMLMNYDE
HHHHHCCCCCCEEEEEECCCHHHHHHCCCHHHHHCCCCEEEEEECHHHHHHHHHHHCCCH
KEFRSVSSGDLGIEEDEKEENEQENNDNAELFTAMKEVLSTKVKDVRASKRLKSHPVVLT
HHHHCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
ADGEISLEMEKIINAMPDDQQIQADKVLEINVNHDIFQSLKAAQGNDDEKFKLYTNLLYN
ECCCEEEEHHHHHCCCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHC
QALLIEGLPINDPVEFTNDICKVMV
CCCEEECCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
GKRKFKAESQKLLDMVINSIYSQREVFLRELISNASDAIDKIYYKALTDDSLSFDVDNY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCE
YIKITPNKEERTLTVVDTGIGMTKEELENNLGVIAKSGSHTFKSENEIKDGHDIIGQFGV
EEEEECCCCCCEEEEEECCCCCCHHHHHCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHH
GFYAAFMVADKVEVVTKSIDSDAAFKWESKGSDGYSITEADKQDIGTTITLYIKENQEEE
HHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCEECCCCHHHCCCEEEEEEECCCCCC
NYDEFLDTFTLQQIIKKYSDFIRYPIKMDVTESKLKEGSEDEYEDVVEEQTINTMVPIWK
CHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
KNKSELTDDDYTNFYQEKRYGFDKPLKHVHINVDGSIRYNAILFIPESAPFNYYTRDYEK
CCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCEEEEEEEEEECCCCCCCHHHHHHH
GLELYSNGVLIMDKCADLLPDYFSFVKGMVDSEDLSLNISREMLQHDRQLKLIAKNIKKK
HHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHCCHHHHHHHHHHHHH
VKQQLVSLLRDERENYEKFFDAFGQQIKFGVYSDYGQNKDELKDLLLFYSSKEKKLVTLE
HHHHHHHHHHHHHHHHHHHHHHHHHHEEECEECCCCCCHHHHHHHHHHHCCCCCEEEEHH
EYVSCMPEDQKYIYYATGDSRDRIEKLPQTELVADKGYEILYFTDEIDEFAIKMLMNYDE
HHHHHCCCCCCEEEEEECCCHHHHHHCCCHHHHHCCCCEEEEEECHHHHHHHHHHHCCCH
KEFRSVSSGDLGIEEDEKEENEQENNDNAELFTAMKEVLSTKVKDVRASKRLKSHPVVLT
HHHHCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
ADGEISLEMEKIINAMPDDQQIQADKVLEINVNHDIFQSLKAAQGNDDEKFKLYTNLLYN
ECCCEEEEHHHHHCCCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHC
QALLIEGLPINDPVEFTNDICKVMV
CCCEEECCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376