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The map label for this gene is xylR [H]

Identifier: 23100579

GI number: 23100579

Start: 3256210

End: 3257412

Strand: Direct

Name: xylR [H]

Synonym: OB3124

Alternate gene names: 23100579

Gene position: 3256210-3257412 (Clockwise)

Preceding gene: 23100575

Following gene: 23100580

Centisome position: 89.69

GC content: 34.0

Gene sequence:

>1203_bases
ATGAAAATAAATCGAACGTGGAATCAGTATGTAGTTAAACAAGAGAATAAGTCTTTAGTCTTTAATACTATTAGACAAAA
TTCTCCCATTTCAAGAGCAGATATCGCACAACAACTAGGCCTTAACAAAAGCACTGTTTCTTCATTAGTAAGCGAACTTA
TTAACGAAGAACTGATTGGAGAAGTTGGTCCAGGAGAGTCAAGTGGAGGAAGACGCCCTGTTATGCTGTTTTTCAATAAT
ACAGCTGGTTACTCTATTGGAATCGATCTCGGTGTAAATTATATATTGGGGGTGTTAACAGATTTACAAGGAAATATTTT
AGAACAAGAACAAGTTACATTTGATAACTTAACTTATGAAGAAATCCTAGTTCATCTAAATGAGGTTATACAGAAACTGA
TTACAATGACTTCAAAAAGTCCATATGGTGTTATCGGTATCGGTGTTGCAGTACCTGGAATTGTTAATAAAGAAGAGAAA
ATACTGCTTGCTCCTAATTTAAATTGGCGGAATATTTCTTTAAAAGAAGAATTAGAGAATCAATTTAATATTCCGGTTAT
TATTGAGAATGAAGCAAATGCGGGTGCGTATGGTGAAGTACAATTTGGCATCGGCAAAGAAAATAAAGAAATTGTATATG
TCAGTGTTGGTGTAGGAATCGGGGTTGGCCTTGTATTAAACAACCAATTGTACAAAGGAAATAATGGATTTTCCGGAGAA
ATGGGGCATATGACTATTGATGCACATGGCGCAAAATGTAGTTGTGGAAGTGAAGGTTGTTGGGAGCTATATGCTTCTGA
GAAAGCATTATTACAATTAGCTAAAAGAAATAAAATCTATACAACCGATCCATATGATTTACTAGACCATATGATCCAAT
TAGCCAAAAATAATGATTCAGTAGCGTTAGAAGCATTTAATGAAATCAGCAAATATTTAGCAATCGGGATCAATAATATT
ATTAATTCATTTAATCCAGAACAAGTCATTATTGGCAATCGAATGTCTGCTGCAAAAAAATGGATTGAGAAACCATTGCT
TGATTCCATTAATAATCAATCACTATGGTTTAGCCAAAAGGATTTAAAAATTGATTTTTCAAGCCTTAACACACATTCGA
ATGCACTTGGGATGGCAGCATTTTCCTCTGAGAGATTCTTAAAAGTAACGATTTCTGGAAACGAAGTAATCCGTGTGAAG
TAA

Upstream 100 bases:

>100_bases
GCAAAAATAACTTTGTTTGTCTACCGGTTAAACAAAGTTTTGTATTTGAAATATAACATGCTATACTAATAATCAATCAG
ATGGGAGAAGGAGCGAATAC

Downstream 100 bases:

>100_bases
AGCAATGGATCCATGATAAACCTAAGTTTTTTCGAACAATAATCCACCATGAAAAATAAAAAATGAGGTGAAATAATGAC
AAACATTAAAAATCCTATTT

Product: transcriptional repressor of the xylose operon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MKINRTWNQYVVKQENKSLVFNTIRQNSPISRADIAQQLGLNKSTVSSLVSELINEELIGEVGPGESSGGRRPVMLFFNN
TAGYSIGIDLGVNYILGVLTDLQGNILEQEQVTFDNLTYEEILVHLNEVIQKLITMTSKSPYGVIGIGVAVPGIVNKEEK
ILLAPNLNWRNISLKEELENQFNIPVIIENEANAGAYGEVQFGIGKENKEIVYVSVGVGIGVGLVLNNQLYKGNNGFSGE
MGHMTIDAHGAKCSCGSEGCWELYASEKALLQLAKRNKIYTTDPYDLLDHMIQLAKNNDSVALEAFNEISKYLAIGINNI
INSFNPEQVIIGNRMSAAKKWIEKPLLDSINNQSLWFSQKDLKIDFSSLNTHSNALGMAAFSSERFLKVTISGNEVIRVK

Sequences:

>Translated_400_residues
MKINRTWNQYVVKQENKSLVFNTIRQNSPISRADIAQQLGLNKSTVSSLVSELINEELIGEVGPGESSGGRRPVMLFFNN
TAGYSIGIDLGVNYILGVLTDLQGNILEQEQVTFDNLTYEEILVHLNEVIQKLITMTSKSPYGVIGIGVAVPGIVNKEEK
ILLAPNLNWRNISLKEELENQFNIPVIIENEANAGAYGEVQFGIGKENKEIVYVSVGVGIGVGLVLNNQLYKGNNGFSGE
MGHMTIDAHGAKCSCGSEGCWELYASEKALLQLAKRNKIYTTDPYDLLDHMIQLAKNNDSVALEAFNEISKYLAIGINNI
INSFNPEQVIIGNRMSAAKKWIEKPLLDSINNQSLWFSQKDLKIDFSSLNTHSNALGMAAFSSERFLKVTISGNEVIRVK
>Mature_400_residues
MKINRTWNQYVVKQENKSLVFNTIRQNSPISRADIAQQLGLNKSTVSSLVSELINEELIGEVGPGESSGGRRPVMLFFNN
TAGYSIGIDLGVNYILGVLTDLQGNILEQEQVTFDNLTYEEILVHLNEVIQKLITMTSKSPYGVIGIGVAVPGIVNKEEK
ILLAPNLNWRNISLKEELENQFNIPVIIENEANAGAYGEVQFGIGKENKEIVYVSVGVGIGVGLVLNNQLYKGNNGFSGE
MGHMTIDAHGAKCSCGSEGCWELYASEKALLQLAKRNKIYTTDPYDLLDHMIQLAKNNDSVALEAFNEISKYLAIGINNI
INSFNPEQVIIGNRMSAAKKWIEKPLLDSINNQSLWFSQKDLKIDFSSLNTHSNALGMAAFSSERFLKVTISGNEVIRVK

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=289, Percent_Identity=29.0657439446367, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI298566315, Length=289, Percent_Identity=29.0657439446367, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI4885285, Length=289, Percent_Identity=29.0657439446367, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI190014632, Length=289, Percent_Identity=29.0657439446367, Blast_Score=105, Evalue=5e-23,
Organism=Escherichia coli, GI1786891, Length=384, Percent_Identity=29.4270833333333, Blast_Score=167, Evalue=8e-43,
Organism=Escherichia coli, GI1787878, Length=385, Percent_Identity=24.1558441558442, Blast_Score=131, Evalue=7e-32,
Organism=Escherichia coli, GI1790522, Length=324, Percent_Identity=22.8395061728395, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87081733, Length=261, Percent_Identity=24.1379310344828, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1787363, Length=267, Percent_Identity=25.4681647940075, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87082127, Length=335, Percent_Identity=20, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87082230, Length=261, Percent_Identity=24.904214559387, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 44162; Mature: 44162

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS01125 ROK ; PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKINRTWNQYVVKQENKSLVFNTIRQNSPISRADIAQQLGLNKSTVSSLVSELINEELIG
CCCCCCHHHHEEEECCCCEEEEEHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
EVGPGESSGGRRPVMLFFNNTAGYSIGIDLGVNYILGVLTDLQGNILEQEQVTFDNLTYE
CCCCCCCCCCCCEEEEEEECCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
EILVHLNEVIQKLITMTSKSPYGVIGIGVAVPGIVNKEEKILLAPNLNWRNISLKEELEN
HHHHHHHHHHHHHHHHCCCCCCCEEEECEECCCCCCCCCCEEECCCCCCCCCCHHHHHHH
QFNIPVIIENEANAGAYGEVQFGIGKENKEIVYVSVGVGIGVGLVLNNQLYKGNNGFSGE
CCCCCEEEECCCCCCCCEEEEECCCCCCCEEEEEEECCCCEEEEEECCEEEECCCCCCCC
MGHMTIDAHGAKCSCGSEGCWELYASEKALLQLAKRNKIYTTDPYDLLDHMIQLAKNNDS
CCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHCCCCC
VALEAFNEISKYLAIGINNIINSFNPEQVIIGNRMSAAKKWIEKPLLDSINNQSLWFSQK
EEHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCEEEEECC
DLKIDFSSLNTHSNALGMAAFSSERFLKVTISGNEVIRVK
CCEEEHHHCCCCCCCEEEEEECCCCEEEEEECCCEEEEEC
>Mature Secondary Structure
MKINRTWNQYVVKQENKSLVFNTIRQNSPISRADIAQQLGLNKSTVSSLVSELINEELIG
CCCCCCHHHHEEEECCCCEEEEEHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
EVGPGESSGGRRPVMLFFNNTAGYSIGIDLGVNYILGVLTDLQGNILEQEQVTFDNLTYE
CCCCCCCCCCCCEEEEEEECCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
EILVHLNEVIQKLITMTSKSPYGVIGIGVAVPGIVNKEEKILLAPNLNWRNISLKEELEN
HHHHHHHHHHHHHHHHCCCCCCCEEEECEECCCCCCCCCCEEECCCCCCCCCCHHHHHHH
QFNIPVIIENEANAGAYGEVQFGIGKENKEIVYVSVGVGIGVGLVLNNQLYKGNNGFSGE
CCCCCEEEECCCCCCCCEEEEECCCCCCCEEEEEEECCCCEEEEEECCEEEECCCCCCCC
MGHMTIDAHGAKCSCGSEGCWELYASEKALLQLAKRNKIYTTDPYDLLDHMIQLAKNNDS
CCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHCCCCC
VALEAFNEISKYLAIGINNIINSFNPEQVIIGNRMSAAKKWIEKPLLDSINNQSLWFSQK
EEHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCEEEEECC
DLKIDFSSLNTHSNALGMAAFSSERFLKVTISGNEVIRVK
CCEEEHHHCCCCCCCEEEEEECCCCEEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2544559 [H]