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The map label for this gene is sigW [H]

Identifier: 23100547

GI number: 23100547

Start: 3216336

End: 3216875

Strand: Reverse

Name: sigW [H]

Synonym: OB3092

Alternate gene names: 23100547

Gene position: 3216875-3216336 (Counterclockwise)

Preceding gene: 23100548

Following gene: 23100546

Centisome position: 88.61

GC content: 35.0

Gene sequence:

>540_bases
ATGGCAGATGACGAGAAGAAGCTGATAAAGAAAATTAAAAAAGGGAATCAGCAAGCGTTTCAAAAGCTTTATCAGTTACA
CGTTGACTATGCACTAAGAACAGCATATGCCATTTCTAAAAATAAGAATGATGCATCCGACATTGTACAGGAGACTTTTA
TACGTGTATTTCGAAATATTGATAGCTATGATATCAACCGTCCCTTCAGAGCTTGGCTCTATCGGATACTCATAAATGAA
TCGAATCGATTATTAAGAAAGCGTACTCGTTCAGAAGTAACCATAGACTCAGAGCAATTATTAGATTATTTAGGTCGACA
GTCAACACAATCTAAACCATTAGATGAGTTAGATGAAGCAATCGATGAATTAGAGGAGCATCATAAAACCGTTATCATAT
TAAAATATTTGAATGGATTTAGTGAAAAAGAAATTGCTGAAATTCTCGAGTTGAATCAAAACACGGTGAAATCAAGGTTA
TATCAAGCAAGGAATAAACTACGTTCCAAGTTAGGAGGGAGAGAACATGAGTGGGAATAA

Upstream 100 bases:

>100_bases
TTTTCGGCAGCTTTTTTTATGAAAAAATAAATAAAATAAAACTTTTCTGTAATCTGATGGGTAGTATTAGTAAGTAAAGG
AGTGAAAAGGAGGCAGTAAT

Downstream 100 bases:

>100_bases
AAACCATTCTTTTGATGAACAGTTGAAAAAATTATTTCAAGAAAAGACCGATATAGCTACAACAGCAAAAGAAGAAACAT
GGATAGCCATTCATCAAACC

Product: RNA polymerase ECF-type sigma factor

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 179; Mature: 178

Protein sequence:

>179_residues
MADDEKKLIKKIKKGNQQAFQKLYQLHVDYALRTAYAISKNKNDASDIVQETFIRVFRNIDSYDINRPFRAWLYRILINE
SNRLLRKRTRSEVTIDSEQLLDYLGRQSTQSKPLDELDEAIDELEEHHKTVIILKYLNGFSEKEIAEILELNQNTVKSRL
YQARNKLRSKLGGREHEWE

Sequences:

>Translated_179_residues
MADDEKKLIKKIKKGNQQAFQKLYQLHVDYALRTAYAISKNKNDASDIVQETFIRVFRNIDSYDINRPFRAWLYRILINE
SNRLLRKRTRSEVTIDSEQLLDYLGRQSTQSKPLDELDEAIDELEEHHKTVIILKYLNGFSEKEIAEILELNQNTVKSRL
YQARNKLRSKLGGREHEWE
>Mature_178_residues
ADDEKKLIKKIKKGNQQAFQKLYQLHVDYALRTAYAISKNKNDASDIVQETFIRVFRNIDSYDINRPFRAWLYRILINES
NRLLRKRTRSEVTIDSEQLLDYLGRQSTQSKPLDELDEAIDELEEHHKTVIILKYLNGFSEKEIAEILELNQNTVKSRLY
QARNKLRSKLGGREHEWE

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=182, Percent_Identity=30.2197802197802, Blast_Score=81, Evalue=3e-17,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 21270; Mature: 21139

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADDEKKLIKKIKKGNQQAFQKLYQLHVDYALRTAYAISKNKNDASDIVQETFIRVFRNI
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
DSYDINRPFRAWLYRILINESNRLLRKRTRSEVTIDSEQLLDYLGRQSTQSKPLDELDEA
CCCCCCCHHHHHHHHHHHHCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHHHH
IDELEEHHKTVIILKYLNGFSEKEIAEILELNQNTVKSRLYQARNKLRSKLGGREHEWE
HHHHHHHHHHEEHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
ADDEKKLIKKIKKGNQQAFQKLYQLHVDYALRTAYAISKNKNDASDIVQETFIRVFRNI
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
DSYDINRPFRAWLYRILINESNRLLRKRTRSEVTIDSEQLLDYLGRQSTQSKPLDELDEA
CCCCCCCHHHHHHHHHHHHCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHHHH
IDELEEHHKTVIILKYLNGFSEKEIAEILELNQNTVKSRLYQARNKLRSKLGGREHEWE
HHHHHHHHHHEEHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]