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The map label for this gene is ligD [H]

Identifier: 23100489

GI number: 23100489

Start: 3143990

End: 3145777

Strand: Direct

Name: ligD [H]

Synonym: OB3034

Alternate gene names: 23100489

Gene position: 3143990-3145777 (Clockwise)

Preceding gene: 23100486

Following gene: 23100493

Centisome position: 86.6

GC content: 35.18

Gene sequence:

>1788_bases
ATGAAGCCGATAGCAAGTACAGAAATTCCTGTTGGTGATGAGTGGATATACGAGGTGAAGTATGATGGGTTTCGTTGCAA
ATTAATATGGTCTGTAGCAAATAAAATAACCTTGATCAGTAAAAATAAGCATAATATCACAAAGAAATTTCCGGAAATTA
TTCAGTGGTGTGAAAATAATTATGAATTCTTCAAAACTGCATTACCACTCGAGTTCGATGGGGAACTAGTAATATTAAAT
CACCGGTACCAGGCGAATTTTGCTCAAATACAAATCCGTGGAAGATTACAAAGTACAGACCGAATTGAAAAAAAAGCAAA
TCTTAGACCTGCAACATTGATGGTATTCGATTTAACCAAACTAAAAGGAAAAAAATTATATCAAAGCAATCTATCTTTAC
GGAAGAAATACCTTGATCAACTCATGCAAGATATACGGGGAGATGGAAGAATTAGATGTGTCGAATCATTCACTTCAGTC
TCAAAAATTAATGAAATTGTATATGCAGCTAAATCTGAAGGTGTCGTAGCTAAAAGAAAAAAAAGCATATACCAAAAGGG
AAAACAACATCAAAGTTGGTTTAAGATTAAAAACTGGCGATTAATACATGGAATTCTAACAGCATATAACCCAAGTAACG
GCTATTTCACAGTTAGTGTACTGGAAAATAATCAGCCTGTTCATATTGGAAAGTGTAAACACGGACTAGAAAAAGATGCT
TCTCAAACCGTACAAAAGCTTTTCCAAGAACAAGGCGAGTTCAAGGATGGTATTTACTATCTACCTCCAGCAATTACGAG
TACAATCCACACATTAGATTTATATGATGAGGAGCTACGAGAACCTGAATTTAAGCATATTACATCATCAATAGCTTATT
CAGAATGCACATTGGATAAATTACAATTAGATATGGCACAACTTCCCCATTCAATTGACATATCTAATACAGATAAATAC
CTTTGGCCAAATAATTATACTAAACAGGATTTATTAGTTTACATTCGTGAAATATCACCTTGGATGTTACCTTTTTTACG
GCAAAAAGCATTGACTATTATTCGCTGTCCAGATGGAATTACGAAGGAATCCTTTTTTCAAAAAAACTTGCCAGACTATG
CCCCAGACTTTTTATCATCCACTTCTGCTCAAGAGAACTATATTGTATGTAATCATCTGAGAAGTATCGTCTGGTTAGCA
AATCATGGTTCGATTGAATACCATATTCCCTTTCAACGGATTGGCCATGTTACACCTTTAGAAATTGTATTTGATTTGGA
TCCGCCCGATCGCGAGCATTTTAAATTAGCTGTACATGCTGCAAATCTCCTAAAGCATATATTAGATGAATTAGAGCTTG
TATCGTTTGTGAAAACATCAGGAAATAAAGGACTACAAGTATATATACCAATCCGAGAAGGAAGCATGACTTACGATGAG
ACATTCCTATTTACAGAAGCTATCGCAAAAACGCTCGAAAAATCATATCCAAACGATTTCACAACCGAACGAATGAAAAA
GAATCGACATAATCGACTTTATATCGATTATGTTCAACACGGGAAAGATAAAACATTGATTGCACCATATTCACCAAGAA
TGACGAAAGAAGGTACTGTATCAACACCACTATATTGGAATGAAGTAAATAACGAGTTAGATCCTACTCATTTTACAATT
GGTAATGTTATCAATCGGGTGCGTGAGATCGGCTGCCCTTTTGCAAACTATCATGATATGCATGAACAGCAACCTATGAA
AAAGATGCTCCGCTTAGTCCGTGGATAA

Upstream 100 bases:

>100_bases
CCTTACAGTTATTTTGCAGTTCGCTTGGTTTTTTATACGAACGGAATAGTAAAAATAATAAAATCAGACAACCTATGATA
GAGGTGGTTATATGGAATGG

Downstream 100 bases:

>100_bases
CATGTATCCTTTTTAATTAAAAACCCGAACCATACTCTATTTTCCTGCTTAGAGCGGTTCGGGTCAGGGCTTAATATAGA
TTTTATTTACCGAAAGTTGG

Product: ATP-dependent DNA ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 595; Mature: 595

Protein sequence:

>595_residues
MKPIASTEIPVGDEWIYEVKYDGFRCKLIWSVANKITLISKNKHNITKKFPEIIQWCENNYEFFKTALPLEFDGELVILN
HRYQANFAQIQIRGRLQSTDRIEKKANLRPATLMVFDLTKLKGKKLYQSNLSLRKKYLDQLMQDIRGDGRIRCVESFTSV
SKINEIVYAAKSEGVVAKRKKSIYQKGKQHQSWFKIKNWRLIHGILTAYNPSNGYFTVSVLENNQPVHIGKCKHGLEKDA
SQTVQKLFQEQGEFKDGIYYLPPAITSTIHTLDLYDEELREPEFKHITSSIAYSECTLDKLQLDMAQLPHSIDISNTDKY
LWPNNYTKQDLLVYIREISPWMLPFLRQKALTIIRCPDGITKESFFQKNLPDYAPDFLSSTSAQENYIVCNHLRSIVWLA
NHGSIEYHIPFQRIGHVTPLEIVFDLDPPDREHFKLAVHAANLLKHILDELELVSFVKTSGNKGLQVYIPIREGSMTYDE
TFLFTEAIAKTLEKSYPNDFTTERMKKNRHNRLYIDYVQHGKDKTLIAPYSPRMTKEGTVSTPLYWNEVNNELDPTHFTI
GNVINRVREIGCPFANYHDMHEQQPMKKMLRLVRG

Sequences:

>Translated_595_residues
MKPIASTEIPVGDEWIYEVKYDGFRCKLIWSVANKITLISKNKHNITKKFPEIIQWCENNYEFFKTALPLEFDGELVILN
HRYQANFAQIQIRGRLQSTDRIEKKANLRPATLMVFDLTKLKGKKLYQSNLSLRKKYLDQLMQDIRGDGRIRCVESFTSV
SKINEIVYAAKSEGVVAKRKKSIYQKGKQHQSWFKIKNWRLIHGILTAYNPSNGYFTVSVLENNQPVHIGKCKHGLEKDA
SQTVQKLFQEQGEFKDGIYYLPPAITSTIHTLDLYDEELREPEFKHITSSIAYSECTLDKLQLDMAQLPHSIDISNTDKY
LWPNNYTKQDLLVYIREISPWMLPFLRQKALTIIRCPDGITKESFFQKNLPDYAPDFLSSTSAQENYIVCNHLRSIVWLA
NHGSIEYHIPFQRIGHVTPLEIVFDLDPPDREHFKLAVHAANLLKHILDELELVSFVKTSGNKGLQVYIPIREGSMTYDE
TFLFTEAIAKTLEKSYPNDFTTERMKKNRHNRLYIDYVQHGKDKTLIAPYSPRMTKEGTVSTPLYWNEVNNELDPTHFTI
GNVINRVREIGCPFANYHDMHEQQPMKKMLRLVRG
>Mature_595_residues
MKPIASTEIPVGDEWIYEVKYDGFRCKLIWSVANKITLISKNKHNITKKFPEIIQWCENNYEFFKTALPLEFDGELVILN
HRYQANFAQIQIRGRLQSTDRIEKKANLRPATLMVFDLTKLKGKKLYQSNLSLRKKYLDQLMQDIRGDGRIRCVESFTSV
SKINEIVYAAKSEGVVAKRKKSIYQKGKQHQSWFKIKNWRLIHGILTAYNPSNGYFTVSVLENNQPVHIGKCKHGLEKDA
SQTVQKLFQEQGEFKDGIYYLPPAITSTIHTLDLYDEELREPEFKHITSSIAYSECTLDKLQLDMAQLPHSIDISNTDKY
LWPNNYTKQDLLVYIREISPWMLPFLRQKALTIIRCPDGITKESFFQKNLPDYAPDFLSSTSAQENYIVCNHLRSIVWLA
NHGSIEYHIPFQRIGHVTPLEIVFDLDPPDREHFKLAVHAANLLKHILDELELVSFVKTSGNKGLQVYIPIREGSMTYDE
TFLFTEAIAKTLEKSYPNDFTTERMKKNRHNRLYIDYVQHGKDKTLIAPYSPRMTKEGTVSTPLYWNEVNNELDPTHFTI
GNVINRVREIGCPFANYHDMHEQQPMKKMLRLVRG

Specific function: Probably involved in the repair of DNA double-strand breaks by non-homologous-end joining (NHEJ) during spore germination [H]

COG id: COG3285

COG function: function code L; Predicted eukaryotic-type DNA primase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR014146
- InterPro:   IPR014145
- InterPro:   IPR014143 [H]

Pfam domain/function: PF01068 DNA_ligase_A_M [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 69265; Mature: 69265

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS00697 DNA_LIGASE_A1 ; PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPIASTEIPVGDEWIYEVKYDGFRCKLIWSVANKITLISKNKHNITKKFPEIIQWCENN
CCCCCCCCCCCCCCEEEEEEECCEEEEEEEEHHCCEEEEECCCCHHHHHHHHHHHHHCCC
YEFFKTALPLEFDGELVILNHRYQANFAQIQIRGRLQSTDRIEKKANLRPATLMVFDLTK
HHHHHHCCCEEECCCEEEEECCCCCCEEEEEEEECCCCHHHHHHHCCCCCEEEEEEEHHH
LKGKKLYQSNLSLRKKYLDQLMQDIRGDGRIRCVESFTSVSKINEIVYAAKSEGVVAKRK
HCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHH
KSIYQKGKQHQSWFKIKNWRLIHGILTAYNPSNGYFTVSVLENNQPVHIGKCKHGLEKDA
HHHHHCCCCCCCHHEECCEEEEEEEEHEECCCCCEEEEEEECCCCCEEEHHHHCCCCCHH
SQTVQKLFQEQGEFKDGIYYLPPAITSTIHTLDLYDEELREPEFKHITSSIAYSECTLDK
HHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHH
LQLDMAQLPHSIDISNTDKYLWPNNYTKQDLLVYIREISPWMLPFLRQKALTIIRCPDGI
HHHHHHHCCCEECCCCCCCEECCCCCCHHHHHHHHHHCCHHHHHHHHHHCEEEEECCCCC
TKESFFQKNLPDYAPDFLSSTSAQENYIVCNHLRSIVWLANHGSIEYHIPFQRIGHVTPL
CHHHHHHHCCCCCCHHHHCCCCCCCCCEEHHHHHHHEEEECCCCEEEEECHHHHCCCCCE
EIVFDLDPPDREHFKLAVHAANLLKHILDELELVSFVKTSGNKGLQVYIPIREGSMTYDE
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCHH
TFLFTEAIAKTLEKSYPNDFTTERMKKNRHNRLYIDYVQHGKDKTLIAPYSPRMTKEGTV
HHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEEECCCCCCEEECCCCCCCCCCCCC
STPLYWNEVNNELDPTHFTIGNVINRVREIGCPFANYHDMHEQQPMKKMLRLVRG
CCCEEECCCCCCCCCCEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKPIASTEIPVGDEWIYEVKYDGFRCKLIWSVANKITLISKNKHNITKKFPEIIQWCENN
CCCCCCCCCCCCCCEEEEEEECCEEEEEEEEHHCCEEEEECCCCHHHHHHHHHHHHHCCC
YEFFKTALPLEFDGELVILNHRYQANFAQIQIRGRLQSTDRIEKKANLRPATLMVFDLTK
HHHHHHCCCEEECCCEEEEECCCCCCEEEEEEEECCCCHHHHHHHCCCCCEEEEEEEHHH
LKGKKLYQSNLSLRKKYLDQLMQDIRGDGRIRCVESFTSVSKINEIVYAAKSEGVVAKRK
HCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHH
KSIYQKGKQHQSWFKIKNWRLIHGILTAYNPSNGYFTVSVLENNQPVHIGKCKHGLEKDA
HHHHHCCCCCCCHHEECCEEEEEEEEHEECCCCCEEEEEEECCCCCEEEHHHHCCCCCHH
SQTVQKLFQEQGEFKDGIYYLPPAITSTIHTLDLYDEELREPEFKHITSSIAYSECTLDK
HHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHH
LQLDMAQLPHSIDISNTDKYLWPNNYTKQDLLVYIREISPWMLPFLRQKALTIIRCPDGI
HHHHHHHCCCEECCCCCCCEECCCCCCHHHHHHHHHHCCHHHHHHHHHHCEEEEECCCCC
TKESFFQKNLPDYAPDFLSSTSAQENYIVCNHLRSIVWLANHGSIEYHIPFQRIGHVTPL
CHHHHHHHCCCCCCHHHHCCCCCCCCCEEHHHHHHHEEEECCCCEEEEECHHHHCCCCCE
EIVFDLDPPDREHFKLAVHAANLLKHILDELELVSFVKTSGNKGLQVYIPIREGSMTYDE
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCHH
TFLFTEAIAKTLEKSYPNDFTTERMKKNRHNRLYIDYVQHGKDKTLIAPYSPRMTKEGTV
HHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEEECCCCCCEEECCCCCCCCCCCCC
STPLYWNEVNNELDPTHFTIGNVINRVREIGCPFANYHDMHEQQPMKKMLRLVRG
CCCEEECCCCCCCCCCEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]