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The map label for this gene is mmgC [H]

Identifier: 23100466

GI number: 23100466

Start: 3120056

End: 3121204

Strand: Reverse

Name: mmgC [H]

Synonym: OB3011

Alternate gene names: 23100466

Gene position: 3121204-3120056 (Counterclockwise)

Preceding gene: 23100467

Following gene: 23100465

Centisome position: 85.97

GC content: 37.51

Gene sequence:

>1149_bases
ATGTTAATGCTATCTGATGAACAAAAAATGTTACAAAAAATGGTGCGTGATTTTGCAACACAAGAAGTGATTCCAGAAGT
AGAGCGAATGGAATCAGAAGATCGTTTTCCGAAAGAATTAATCCAAAAAATGGGGGAGCTTGGATTAATGGGAATTCCTA
TTCCAGAGGCATATGGAGGGAGTGGGATGAGTTATACCTCATATATTCAAGTCATCCATGAAATATCTAAGTTTAGTGCT
ACCTTAGGGGTAATCCTATCGGTACATACATCGGTTGGAACAAATCCGATTTTGTATTTTGGTACAGAAGATCAAAAACA
AAGGTTTATACCTAAATTAGCAAAAGGAGAGTATTTAGGTGCTTTTGCTTTAACTGAATCAGGATCAGGGTCGGATGCAA
GTAGTATGAAAACCACTGCTAAATTAATAGATGATATGTATGTTTTGAATGGATCAAAGGTTTTTATTACCAATGGAGGA
GAAGCAGATACGTATATTACATTTGCTCGAACCGGTGATTCGCCAAAAGACATCAGTGCATTTATCGTCGAAAAAGACGC
TCCTGGTTTTATTATTGGAAAAAAAGAAAAGAAAATGGGATTGCATGGATCGAATACAGTGGAAATTATCTTTGAAAACT
GTCGAATTCCGAAAGAAAACCTACTAGGCGAAAGAGGCAAGGGATTTAAGATTGCAATGGCAAATCTCAATATAGGTCGT
ATTGGTATTGCTGCTCAAGGACTTGGAATAGCAGAAGCAGCATTAAATTATGCAGTTACTTATGCAAAAGAGAGAGAACA
GTTTGGGAAGCCCATCGCAGCGAACCAGGGGATATCTTTTAAATTGGCCGAGATGGCAACGAATGTAGAGTCTGCGAAGC
TATTAACATATCAGGCTGCTGCATTGATTGAAGCGGGAAAGCAATGTGGTAAAGAAGCATCAATGGCAAAAATGATGGCA
ACAAAAACAGCAATGAATAATGCAATAGAAGCAGTTCAAGTATTTGGCGGATACGGTTATACAAAGGAGTATCCTGTAGA
AAGATTATTCCGGGATGCAAAAGTTACAGAAATATACGAAGGTACCAATGAAATTCAGCATATTGTAATTGCAAAACATC
TACTAAATGATGAAGGGATGCATGGTTAA

Upstream 100 bases:

>100_bases
TTAAGGCAGTATGTTAAAGCAGGTCGTCTAGGTAAGAAAGTAGGTCGGGGTTTTTACACATATGATTAATACTCACTAGA
GAGAGGTGTCTGTCATGTCG

Downstream 100 bases:

>100_bases
TGAATTTTCAATTAACAGAAGAACAAGAAATGCTGCGTAAAATGGTCCGCGATTTTGCGGAAAAAGAAGTTGCACCTACA
GCATCTGAGCGTGATGAGGA

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MLMLSDEQKMLQKMVRDFATQEVIPEVERMESEDRFPKELIQKMGELGLMGIPIPEAYGGSGMSYTSYIQVIHEISKFSA
TLGVILSVHTSVGTNPILYFGTEDQKQRFIPKLAKGEYLGAFALTESGSGSDASSMKTTAKLIDDMYVLNGSKVFITNGG
EADTYITFARTGDSPKDISAFIVEKDAPGFIIGKKEKKMGLHGSNTVEIIFENCRIPKENLLGERGKGFKIAMANLNIGR
IGIAAQGLGIAEAALNYAVTYAKEREQFGKPIAANQGISFKLAEMATNVESAKLLTYQAAALIEAGKQCGKEASMAKMMA
TKTAMNNAIEAVQVFGGYGYTKEYPVERLFRDAKVTEIYEGTNEIQHIVIAKHLLNDEGMHG

Sequences:

>Translated_382_residues
MLMLSDEQKMLQKMVRDFATQEVIPEVERMESEDRFPKELIQKMGELGLMGIPIPEAYGGSGMSYTSYIQVIHEISKFSA
TLGVILSVHTSVGTNPILYFGTEDQKQRFIPKLAKGEYLGAFALTESGSGSDASSMKTTAKLIDDMYVLNGSKVFITNGG
EADTYITFARTGDSPKDISAFIVEKDAPGFIIGKKEKKMGLHGSNTVEIIFENCRIPKENLLGERGKGFKIAMANLNIGR
IGIAAQGLGIAEAALNYAVTYAKEREQFGKPIAANQGISFKLAEMATNVESAKLLTYQAAALIEAGKQCGKEASMAKMMA
TKTAMNNAIEAVQVFGGYGYTKEYPVERLFRDAKVTEIYEGTNEIQHIVIAKHLLNDEGMHG
>Mature_382_residues
MLMLSDEQKMLQKMVRDFATQEVIPEVERMESEDRFPKELIQKMGELGLMGIPIPEAYGGSGMSYTSYIQVIHEISKFSA
TLGVILSVHTSVGTNPILYFGTEDQKQRFIPKLAKGEYLGAFALTESGSGSDASSMKTTAKLIDDMYVLNGSKVFITNGG
EADTYITFARTGDSPKDISAFIVEKDAPGFIIGKKEKKMGLHGSNTVEIIFENCRIPKENLLGERGKGFKIAMANLNIGR
IGIAAQGLGIAEAALNYAVTYAKEREQFGKPIAANQGISFKLAEMATNVESAKLLTYQAAALIEAGKQCGKEASMAKMMA
TKTAMNNAIEAVQVFGGYGYTKEYPVERLFRDAKVTEIYEGTNEIQHIVIAKHLLNDEGMHG

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=375, Percent_Identity=48.8, Blast_Score=368, Evalue=1e-102,
Organism=Homo sapiens, GI4501859, Length=373, Percent_Identity=43.1635388739946, Blast_Score=314, Evalue=8e-86,
Organism=Homo sapiens, GI7656849, Length=376, Percent_Identity=40.6914893617021, Blast_Score=288, Evalue=8e-78,
Organism=Homo sapiens, GI226958412, Length=375, Percent_Identity=36.8, Blast_Score=280, Evalue=1e-75,
Organism=Homo sapiens, GI21361497, Length=367, Percent_Identity=41.6893732970027, Blast_Score=280, Evalue=2e-75,
Organism=Homo sapiens, GI187960098, Length=379, Percent_Identity=39.5778364116095, Blast_Score=275, Evalue=4e-74,
Organism=Homo sapiens, GI4557231, Length=379, Percent_Identity=39.5778364116095, Blast_Score=275, Evalue=5e-74,
Organism=Homo sapiens, GI226958414, Length=339, Percent_Identity=38.3480825958702, Blast_Score=265, Evalue=4e-71,
Organism=Homo sapiens, GI76496475, Length=348, Percent_Identity=39.367816091954, Blast_Score=241, Evalue=6e-64,
Organism=Homo sapiens, GI4557235, Length=348, Percent_Identity=39.367816091954, Blast_Score=241, Evalue=6e-64,
Organism=Homo sapiens, GI4501857, Length=380, Percent_Identity=37.3684210526316, Blast_Score=238, Evalue=7e-63,
Organism=Homo sapiens, GI4503943, Length=372, Percent_Identity=33.8709677419355, Blast_Score=202, Evalue=3e-52,
Organism=Homo sapiens, GI7669494, Length=360, Percent_Identity=34.1666666666667, Blast_Score=192, Evalue=3e-49,
Organism=Homo sapiens, GI48976061, Length=398, Percent_Identity=27.6381909547739, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI211971008, Length=398, Percent_Identity=27.6381909547739, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI38505218, Length=399, Percent_Identity=28.0701754385965, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI156104864, Length=352, Percent_Identity=23.2954545454545, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI156104866, Length=352, Percent_Identity=23.2954545454545, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI218563752, Length=251, Percent_Identity=26.6932270916335, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI87081958, Length=382, Percent_Identity=30.8900523560209, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1786223, Length=378, Percent_Identity=28.5714285714286, Blast_Score=164, Evalue=9e-42,
Organism=Escherichia coli, GI87081702, Length=360, Percent_Identity=25, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87082384, Length=301, Percent_Identity=24.9169435215947, Blast_Score=85, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17534899, Length=384, Percent_Identity=40.3645833333333, Blast_Score=297, Evalue=7e-81,
Organism=Caenorhabditis elegans, GI17508101, Length=371, Percent_Identity=40.9703504043127, Blast_Score=295, Evalue=2e-80,
Organism=Caenorhabditis elegans, GI17506239, Length=377, Percent_Identity=38.7267904509284, Blast_Score=291, Evalue=3e-79,
Organism=Caenorhabditis elegans, GI17569725, Length=385, Percent_Identity=40, Blast_Score=287, Evalue=6e-78,
Organism=Caenorhabditis elegans, GI17570075, Length=386, Percent_Identity=38.860103626943, Blast_Score=284, Evalue=5e-77,
Organism=Caenorhabditis elegans, GI17538396, Length=378, Percent_Identity=35.4497354497354, Blast_Score=273, Evalue=9e-74,
Organism=Caenorhabditis elegans, GI71985184, Length=382, Percent_Identity=37.9581151832461, Blast_Score=250, Evalue=8e-67,
Organism=Caenorhabditis elegans, GI71990804, Length=321, Percent_Identity=41.7445482866044, Blast_Score=240, Evalue=9e-64,
Organism=Caenorhabditis elegans, GI17533517, Length=365, Percent_Identity=36.4383561643836, Blast_Score=239, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI17534353, Length=371, Percent_Identity=31.8059299191375, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI71985192, Length=329, Percent_Identity=38.2978723404255, Blast_Score=208, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=39.8268398268398, Blast_Score=189, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI71982178, Length=268, Percent_Identity=35.4477611940299, Blast_Score=181, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI17505929, Length=376, Percent_Identity=29.7872340425532, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17551932, Length=376, Percent_Identity=28.1914893617021, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17531909, Length=244, Percent_Identity=31.9672131147541, Blast_Score=134, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI17562446, Length=331, Percent_Identity=26.8882175226586, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17531913, Length=179, Percent_Identity=31.8435754189944, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI86563381, Length=341, Percent_Identity=27.8592375366569, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI86563383, Length=341, Percent_Identity=27.8592375366569, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21356377, Length=376, Percent_Identity=48.4042553191489, Blast_Score=357, Evalue=1e-98,
Organism=Drosophila melanogaster, GI24646207, Length=378, Percent_Identity=44.4444444444444, Blast_Score=328, Evalue=4e-90,
Organism=Drosophila melanogaster, GI24666513, Length=379, Percent_Identity=40.6332453825858, Blast_Score=301, Evalue=4e-82,
Organism=Drosophila melanogaster, GI24660351, Length=377, Percent_Identity=39.5225464190981, Blast_Score=280, Evalue=1e-75,
Organism=Drosophila melanogaster, GI21355753, Length=380, Percent_Identity=34.7368421052632, Blast_Score=256, Evalue=3e-68,
Organism=Drosophila melanogaster, GI281363737, Length=393, Percent_Identity=35.6234096692112, Blast_Score=228, Evalue=5e-60,
Organism=Drosophila melanogaster, GI19920834, Length=373, Percent_Identity=31.3672922252011, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI281365206, Length=425, Percent_Identity=24.9411764705882, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24585193, Length=425, Percent_Identity=24.9411764705882, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24585195, Length=425, Percent_Identity=24.9411764705882, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24585191, Length=425, Percent_Identity=24.9411764705882, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI221473076, Length=311, Percent_Identity=26.3665594855305, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45550141, Length=311, Percent_Identity=26.3665594855305, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24652780, Length=288, Percent_Identity=24.3055555555556, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 41696; Mature: 41696

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMLSDEQKMLQKMVRDFATQEVIPEVERMESEDRFPKELIQKMGELGLMGIPIPEAYGG
CCEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEECCCCCCCCCC
SGMSYTSYIQVIHEISKFSATLGVILSVHTSVGTNPILYFGTEDQKQRFIPKLAKGEYLG
CCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCEEEECCCHHHHHHHHHHHCCCEEE
AFALTESGSGSDASSMKTTAKLIDDMYVLNGSKVFITNGGEADTYITFARTGDSPKDISA
EEEEECCCCCCCHHHHHHHHHHHHHHEEECCCEEEEECCCCCCEEEEEEECCCCCCCCEE
FIVEKDAPGFIIGKKEKKMGLHGSNTVEIIFENCRIPKENLLGERGKGFKIAMANLNIGR
EEEECCCCCEEEECCHHHCCCCCCCEEEEEEECCCCCHHHHCCCCCCCEEEEEEECCCCE
IGIAAQGLGIAEAALNYAVTYAKEREQFGKPIAANQGISFKLAEMATNVESAKLLTYQAA
EEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHCCCCHHHHHHHHHH
ALIEAGKQCGKEASMAKMMATKTAMNNAIEAVQVFGGYGYTKEYPVERLFRDAKVTEIYE
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCHHHHHHH
GTNEIQHIVIAKHLLNDEGMHG
CHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLMLSDEQKMLQKMVRDFATQEVIPEVERMESEDRFPKELIQKMGELGLMGIPIPEAYGG
CCEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEECCCCCCCCCC
SGMSYTSYIQVIHEISKFSATLGVILSVHTSVGTNPILYFGTEDQKQRFIPKLAKGEYLG
CCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCEEEECCCHHHHHHHHHHHCCCEEE
AFALTESGSGSDASSMKTTAKLIDDMYVLNGSKVFITNGGEADTYITFARTGDSPKDISA
EEEEECCCCCCCHHHHHHHHHHHHHHEEECCCEEEEECCCCCCEEEEEEECCCCCCCCEE
FIVEKDAPGFIIGKKEKKMGLHGSNTVEIIFENCRIPKENLLGERGKGFKIAMANLNIGR
EEEECCCCCEEEECCHHHCCCCCCCEEEEEEECCCCCHHHHCCCCCCCEEEEEEECCCCE
IGIAAQGLGIAEAALNYAVTYAKEREQFGKPIAANQGISFKLAEMATNVESAKLLTYQAA
EEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHCCCCHHHHHHHHHH
ALIEAGKQCGKEASMAKMMATKTAMNNAIEAVQVFGGYGYTKEYPVERLFRDAKVTEIYE
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCHHHHHHH
GTNEIQHIVIAKHLLNDEGMHG
CHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]