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The map label for this gene is fabZ

Identifier: 23100401

GI number: 23100401

Start: 3052586

End: 3053008

Strand: Reverse

Name: fabZ

Synonym: OB2946

Alternate gene names: 23100401

Gene position: 3053008-3052586 (Counterclockwise)

Preceding gene: 23100403

Following gene: 23100400

Centisome position: 84.09

GC content: 37.35

Gene sequence:

>423_bases
ATGATGGACGTGGAACAAGTTAAAGAAATCATTCCACACCGTTATCCATTTTTATTAGTGGATAAAGTGGTAGAAATACA
AGAAGGCGAAAAAGTGACTGCATTAAAAAATGTATCGGTAAATGAACCATTTTTCCAGGGGCATTTTCCAGAGTATCCTG
TGATGCCAGGTGTACTAATTTTGGAAGCTCTTGCGCAAACAGGAGCAATTGCTGTTTTAAATATAGAGGAGAATAAAGGG
AAAATTGGCTTTCTTGCAGGTGTTGACAAATGCCGATTTAAACGTCAAGTAAAACCCGGAGACCAATTAAATTTACAAGT
AGAAATTATAAGAATGAAGGGTCCAATCGGAAAAGGAAAAGGAATTGCGACTGTAGATGGTGAAGTAGCATGCGAGGCTG
AAATTACCTTTGCTATCAAATAA

Upstream 100 bases:

>100_bases
TACCCATCTTTACATTATTCCAAAACATATACAAGTATTTCTTTCCCTATCTATATTCGCTATAATAGGGATAAATGCTA
CATAGAAGGAGCTGTATACA

Downstream 100 bases:

>100_bases
TCATTCTTTGTCGAAAGTGTAACCAAATAACATCTTGATTTTTTATAAAATGTATTTTTTTTCTATCTTTGGTTAATCTA
ATCACGAAAGTTGATTATCA

Product: hydroxymyristoyl-[acyl carrier protein] dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MMDVEQVKEIIPHRYPFLLVDKVVEIQEGEKVTALKNVSVNEPFFQGHFPEYPVMPGVLILEALAQTGAIAVLNIEENKG
KIGFLAGVDKCRFKRQVKPGDQLNLQVEIIRMKGPIGKGKGIATVDGEVACEAEITFAIK

Sequences:

>Translated_140_residues
MMDVEQVKEIIPHRYPFLLVDKVVEIQEGEKVTALKNVSVNEPFFQGHFPEYPVMPGVLILEALAQTGAIAVLNIEENKG
KIGFLAGVDKCRFKRQVKPGDQLNLQVEIIRMKGPIGKGKGIATVDGEVACEAEITFAIK
>Mature_140_residues
MMDVEQVKEIIPHRYPFLLVDKVVEIQEGEKVTALKNVSVNEPFFQGHFPEYPVMPGVLILEALAQTGAIAVLNIEENKG
KIGFLAGVDKCRFKRQVKPGDQLNLQVEIIRMKGPIGKGKGIATVDGEVACEAEITFAIK

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=139, Percent_Identity=49.6402877697842, Blast_Score=144, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_OCEIH (Q8EMB1)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_693868.1
- ProteinModelPortal:   Q8EMB1
- SMR:   Q8EMB1
- GeneID:   1016767
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB2946
- NMPDR:   fig|221109.1.peg.2949
- HOGENOM:   HBG433282
- OMA:   NVSANES
- BioCyc:   OIHE221109:OB2946-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 15431; Mature: 15431

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: ACT_SITE 48-48

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDVEQVKEIIPHRYPFLLVDKVVEIQEGEKVTALKNVSVNEPFFQGHFPEYPVMPGVLI
CCCHHHHHHHCCCCCCEEEEHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHH
LEALAQTGAIAVLNIEENKGKIGFLAGVDKCRFKRQVKPGDQLNLQVEIIRMKGPIGKGK
HHHHHHCCCEEEEEEECCCCCEEEEECCHHHHHHCCCCCCCCEEEEEEEEEEECCCCCCC
GIATVDGEVACEAEITFAIK
CEEEECCCEEEEEEEEEEEC
>Mature Secondary Structure
MMDVEQVKEIIPHRYPFLLVDKVVEIQEGEKVTALKNVSVNEPFFQGHFPEYPVMPGVLI
CCCHHHHHHHCCCCCCEEEEHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHH
LEALAQTGAIAVLNIEENKGKIGFLAGVDKCRFKRQVKPGDQLNLQVEIIRMKGPIGKGK
HHHHHHCCCEEEEEEECCCCCEEEEECCHHHHHHCCCCCCCCEEEEEEEEEEECCCCCCC
GIATVDGEVACEAEITFAIK
CEEEECCCEEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376