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The map label for this gene is pdh [H]

Identifier: 23100333

GI number: 23100333

Start: 2964400

End: 2965539

Strand: Reverse

Name: pdh [H]

Synonym: OB2878

Alternate gene names: 23100333

Gene position: 2965539-2964400 (Counterclockwise)

Preceding gene: 23100334

Following gene: 23100332

Centisome position: 81.68

GC content: 39.74

Gene sequence:

>1140_bases
TTGAAACAGCTTGAATTTGTCAAACCGAAGGAGAAAAATACATTTGAAAAAATAGCTAACCATGAACAGGTAGTGTTCTG
TAATGATCCGGCAACGGGACTTCAAGCAATTATTGCCATTCATGATACTACACTTGGTCCTGCATTGGGCGGAACAAGGA
TGTATCCATATAAAAGTGTGGATGATGCATTGGAAGATGTCCTGCGACTGTCAGAAGGAATGACCTATAAATGTGCAGCT
TCGGGTCTTGATTTTGGTGGAGGAAAAGCAGTCATCATTGGCGATCCTGAAAAAGACAAGTCTCCTGCATTATTTCGGTC
ATTTGGACAATTTGTTGACTCTTTGAATGGACGTTTTTATACAGGTACAGATATGGGAACAACAACCGATGACTTTGTGG
AGGCATTTAAAGAAACGAATTTTATCAATGGAATTCCTGAAGTATATGGAGGTAGTGGAGACTCTTCCATCTCCACCGCT
TGTGGAGTAATCCATGCTTTAGAGGCAACCAATGAATACCTATTTAATAATAATGATTTAGGAAACAGAACTTATGCGAT
TCAAGGGTTAGGAAAAGTCGGTTATAAGGTTGCCGAACAACTATTGGAAGCTGGAGCAAAATTGTATATTACGGATCTTA
ATCAAGATGTGATGACACAGCTTAACACAAAAGCGAAAGATACAAATGGTGAAGTAGAACAGGTAGATAGTGAAGCTATT
TACAGTACGGATGCAGATATTTTTATCCCTTGTGCAATGGGGGCGATTATCAATGATCAGACGATTGGTCAGTTGAAAGT
AAAAGCGATTGTCGGTTCGGCAAACAATCAATTGCAAAGCCCGGCCCATGCGAAAATGTTGCAAGAGAAAGGGATTTTAT
ATGCACCAGATTATATTGTCAATGCCGGAGGACTGATACAAGTTGCTGATGAACTATATGGCCCGAATACGAAACGAGTA
CTTGTAAAGACAAAAGCGATATACCGTTCCCTTTTAGATATCTATGTACAAGCTGAATTGGATGCGATTACAACAGTAGA
AGCGGCAAATAGGAAAGTACGCAGTGTATTGGAAGAACAGCGGAATCGAAATAACTTTTATTCTCGCAAGCGAAGACCGA
AATGGAATATCAGAGAGTAA

Upstream 100 bases:

>100_bases
TCATCGGAGAAGGTGAAGTGAAGCAGTCAATTCTGCCCAAAAATACGATGAAAAGCAAATTAGATATACAAATTGCAGCT
AAATAAATGGAGGTGTTTTT

Downstream 100 bases:

>100_bases
TTCCTTTAAGAAAGATTTTACTTATGGGAACAAAAATTTGGAGCTAAAGAGGTGCTGACCATGAAACGAAATATGCAGGA
AGAATTTCCAATGATACGAA

Product: phenylalanine dehydrogenase

Products: NA

Alternate protein names: PheDH [H]

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MKQLEFVKPKEKNTFEKIANHEQVVFCNDPATGLQAIIAIHDTTLGPALGGTRMYPYKSVDDALEDVLRLSEGMTYKCAA
SGLDFGGGKAVIIGDPEKDKSPALFRSFGQFVDSLNGRFYTGTDMGTTTDDFVEAFKETNFINGIPEVYGGSGDSSISTA
CGVIHALEATNEYLFNNNDLGNRTYAIQGLGKVGYKVAEQLLEAGAKLYITDLNQDVMTQLNTKAKDTNGEVEQVDSEAI
YSTDADIFIPCAMGAIINDQTIGQLKVKAIVGSANNQLQSPAHAKMLQEKGILYAPDYIVNAGGLIQVADELYGPNTKRV
LVKTKAIYRSLLDIYVQAELDAITTVEAANRKVRSVLEEQRNRNNFYSRKRRPKWNIRE

Sequences:

>Translated_379_residues
MKQLEFVKPKEKNTFEKIANHEQVVFCNDPATGLQAIIAIHDTTLGPALGGTRMYPYKSVDDALEDVLRLSEGMTYKCAA
SGLDFGGGKAVIIGDPEKDKSPALFRSFGQFVDSLNGRFYTGTDMGTTTDDFVEAFKETNFINGIPEVYGGSGDSSISTA
CGVIHALEATNEYLFNNNDLGNRTYAIQGLGKVGYKVAEQLLEAGAKLYITDLNQDVMTQLNTKAKDTNGEVEQVDSEAI
YSTDADIFIPCAMGAIINDQTIGQLKVKAIVGSANNQLQSPAHAKMLQEKGILYAPDYIVNAGGLIQVADELYGPNTKRV
LVKTKAIYRSLLDIYVQAELDAITTVEAANRKVRSVLEEQRNRNNFYSRKRRPKWNIRE
>Mature_379_residues
MKQLEFVKPKEKNTFEKIANHEQVVFCNDPATGLQAIIAIHDTTLGPALGGTRMYPYKSVDDALEDVLRLSEGMTYKCAA
SGLDFGGGKAVIIGDPEKDKSPALFRSFGQFVDSLNGRFYTGTDMGTTTDDFVEAFKETNFINGIPEVYGGSGDSSISTA
CGVIHALEATNEYLFNNNDLGNRTYAIQGLGKVGYKVAEQLLEAGAKLYITDLNQDVMTQLNTKAKDTNGEVEQVDSEAI
YSTDADIFIPCAMGAIINDQTIGQLKVKAIVGSANNQLQSPAHAKMLQEKGILYAPDYIVNAGGLIQVADELYGPNTKRV
LVKTKAIYRSLLDIYVQAELDAITTVEAANRKVRSVLEEQRNRNNFYSRKRRPKWNIRE

Specific function: Unknown

COG id: COG0334

COG function: function code E; Glutamate dehydrogenase/leucine dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Glu/Leu/Phe/Val dehydrogenases family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17544676, Length=313, Percent_Identity=27.4760383386581, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45553475, Length=306, Percent_Identity=27.4509803921569, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI45549226, Length=306, Percent_Identity=27.4509803921569, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24649283, Length=298, Percent_Identity=27.1812080536913, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24649460, Length=271, Percent_Identity=26.5682656826568, Blast_Score=72, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006095
- InterPro:   IPR006096
- InterPro:   IPR006097
- InterPro:   IPR016211
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00208 ELFV_dehydrog; PF02812 ELFV_dehydrog_N [H]

EC number: =1.4.1.20 [H]

Molecular weight: Translated: 41625; Mature: 41625

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00074 GLFV_DEHYDROGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLEFVKPKEKNTFEKIANHEQVVFCNDPATGLQAIIAIHDTTLGPALGGTRMYPYKSV
CCCCCCCCCCCCCHHHHHCCCCEEEEECCCCHHHHEEEEEECCCCCCCCCCCCCCCCCCH
DDALEDVLRLSEGMTYKCAASGLDFGGGKAVIIGDPEKDKSPALFRSFGQFVDSLNGRFY
HHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEE
TGTDMGTTTDDFVEAFKETNFINGIPEVYGGSGDSSISTACGVIHALEATNEYLFNNNDL
ECCCCCCCHHHHHHHHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCC
GNRTYAIQGLGKVGYKVAEQLLEAGAKLYITDLNQDVMTQLNTKAKDTNGEVEQVDSEAI
CCEEEEEECCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHCCCCCCCCCHHHHHCCHHH
YSTDADIFIPCAMGAIINDQTIGQLKVKAIVGSANNQLQSPAHAKMLQEKGILYAPDYIV
CCCCCCEEEEEHHCHHCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCEECCHHEE
NAGGLIQVADELYGPNTKRVLVKTKAIYRSLLDIYVQAELDAITTVEAANRKVRSVLEEQ
CCCCCEEEHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNRNNFYSRKRRPKWNIRE
HCCCHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKQLEFVKPKEKNTFEKIANHEQVVFCNDPATGLQAIIAIHDTTLGPALGGTRMYPYKSV
CCCCCCCCCCCCCHHHHHCCCCEEEEECCCCHHHHEEEEEECCCCCCCCCCCCCCCCCCH
DDALEDVLRLSEGMTYKCAASGLDFGGGKAVIIGDPEKDKSPALFRSFGQFVDSLNGRFY
HHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEE
TGTDMGTTTDDFVEAFKETNFINGIPEVYGGSGDSSISTACGVIHALEATNEYLFNNNDL
ECCCCCCCHHHHHHHHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCC
GNRTYAIQGLGKVGYKVAEQLLEAGAKLYITDLNQDVMTQLNTKAKDTNGEVEQVDSEAI
CCEEEEEECCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHCCCCCCCCCHHHHHCCHHH
YSTDADIFIPCAMGAIINDQTIGQLKVKAIVGSANNQLQSPAHAKMLQEKGILYAPDYIV
CCCCCCEEEEEHHCHHCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCEECCHHEE
NAGGLIQVADELYGPNTKRVLVKTKAIYRSLLDIYVQAELDAITTVEAANRKVRSVLEEQ
CCCCCEEEHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNRNNFYSRKRRPKWNIRE
HCCCHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2838396 [H]