Click here to switch to the map view.

The map label for this gene is tfdDII [H]

Identifier: 23100298

GI number: 23100298

Start: 2926661

End: 2927836

Strand: Reverse

Name: tfdDII [H]

Synonym: OB2843

Alternate gene names: 23100298

Gene position: 2927836-2926661 (Counterclockwise)

Preceding gene: 23100299

Following gene: 23100297

Centisome position: 80.64

GC content: 37.5

Gene sequence:

>1176_bases
ATGAAAATTACGGATTTGGAATTACATGCAGTCGGTATTCCTCGTCATACAGGATTTGTGAATAAACATGTTATTGTTAA
AATTCATACTGACGAAGGTTTAACAGGGATCGGTGAAATGTCTGATTTCTCCCACTTACCCCTTTATTCGGTGGATCTTC
ATGATTTAAAACAAGGACTTTTGTCCATTCTATTAGGTCAGAATCCATTTGATTTGATGAAAATTAATAAGGAATTAACC
GATAATTTCCCAGAAACGATGTACTATTATGAAAAAGGAAGTTTTATAAGAAACGGGATAGATAATGCATTACATGATTT
ATGCGCAAAGTATTTAGATATTTCTGTATCGGATTTTCTAGGAGGTAGAGTCAAAGAAAAAATAAAAGTCTGCTATCCGA
TTTTTAGACATCGATTCTCGGAGGAAGTAGAAAGCAATCTTGATGTGGTCCGTCAAAAATTGGAACAGGGTTTTGATGTT
TTTCGATTATACGTAGGGAAAAACCTTGATGCGGATGAGGAGTTTTTATCTAGGGTGAAAGAAGAATTTGGCTCTAGGGT
ACGTATCAAATCCTATGATTTTAGTCATCTACTAAACTGGAAAGATGCTCACCGGGCAATCAAGCGTCTAACCAAATATG
ATTTGGGATTAGAAATGATAGAAAGTCCAGCACCGAGGAATGACTTTGATGGTTTGTATCAACTAAGACTAAAGACAGAC
TATCCAATCAGTGAACATGTGTGGAGTTTTAAACAGCAACAAGAAATGATAAAAAAAGATGCGATCGACATCTTTAATAT
CTCCCCGGTATTTATTGGCGGGCTCACATCTGCTAAAAAAGCAGCCTATGCAGCGGAAGTAGCAAGTAAAGATGTGGTTC
TGGGAACGACCCAAGAATTATCTGTTGGGACGGCAGCCATGGCTCATCTAGGATGCTCTTTAACAAATATAAACCACACT
TCTGATCCTACTGGTCCAGAGCTTTATGTGGGGGATGTGGTCAAAAATAGAGTTACCTATAAAGATGGGTATCTGTATGC
TCCAGACCGGAGTGTAAAGGGACTTGGTATTGAACTTGATGAATCATTATTAGCAAAATATCAAGTACCTGATTTGAGTT
GGGATAATGTGACAGTGCATCAACTTCAAGACCGTACAGCTGATACAAAATCTTAA

Upstream 100 bases:

>100_bases
AGATGCTGCAAATGAAATCATATCAGTAAAAAATGGCAATGCTCCAGAACACTTAATTCATCCGGTGACAACATAATTTT
AATAGGAGAGGTGACAAATG

Downstream 100 bases:

>100_bases
AACTGTATAGAGAAGGAAATCAAGCGATGGAATAATTGCTACGTAGAATAGTAGCAGTTTGTTCCATGGGATATTTTATT
TTTTATTTGTCGGACAAATA

Product: muconate cycloisomerase

Products: NA

Alternate protein names: Muconate cycloisomerase II [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MKITDLELHAVGIPRHTGFVNKHVIVKIHTDEGLTGIGEMSDFSHLPLYSVDLHDLKQGLLSILLGQNPFDLMKINKELT
DNFPETMYYYEKGSFIRNGIDNALHDLCAKYLDISVSDFLGGRVKEKIKVCYPIFRHRFSEEVESNLDVVRQKLEQGFDV
FRLYVGKNLDADEEFLSRVKEEFGSRVRIKSYDFSHLLNWKDAHRAIKRLTKYDLGLEMIESPAPRNDFDGLYQLRLKTD
YPISEHVWSFKQQQEMIKKDAIDIFNISPVFIGGLTSAKKAAYAAEVASKDVVLGTTQELSVGTAAMAHLGCSLTNINHT
SDPTGPELYVGDVVKNRVTYKDGYLYAPDRSVKGLGIELDESLLAKYQVPDLSWDNVTVHQLQDRTADTKS

Sequences:

>Translated_391_residues
MKITDLELHAVGIPRHTGFVNKHVIVKIHTDEGLTGIGEMSDFSHLPLYSVDLHDLKQGLLSILLGQNPFDLMKINKELT
DNFPETMYYYEKGSFIRNGIDNALHDLCAKYLDISVSDFLGGRVKEKIKVCYPIFRHRFSEEVESNLDVVRQKLEQGFDV
FRLYVGKNLDADEEFLSRVKEEFGSRVRIKSYDFSHLLNWKDAHRAIKRLTKYDLGLEMIESPAPRNDFDGLYQLRLKTD
YPISEHVWSFKQQQEMIKKDAIDIFNISPVFIGGLTSAKKAAYAAEVASKDVVLGTTQELSVGTAAMAHLGCSLTNINHT
SDPTGPELYVGDVVKNRVTYKDGYLYAPDRSVKGLGIELDESLLAKYQVPDLSWDNVTVHQLQDRTADTKS
>Mature_391_residues
MKITDLELHAVGIPRHTGFVNKHVIVKIHTDEGLTGIGEMSDFSHLPLYSVDLHDLKQGLLSILLGQNPFDLMKINKELT
DNFPETMYYYEKGSFIRNGIDNALHDLCAKYLDISVSDFLGGRVKEKIKVCYPIFRHRFSEEVESNLDVVRQKLEQGFDV
FRLYVGKNLDADEEFLSRVKEEFGSRVRIKSYDFSHLLNWKDAHRAIKRLTKYDLGLEMIESPAPRNDFDGLYQLRLKTD
YPISEHVWSFKQQQEMIKKDAIDIFNISPVFIGGLTSAKKAAYAAEVASKDVVLGTTQELSVGTAAMAHLGCSLTNINHT
SDPTGPELYVGDVVKNRVTYKDGYLYAPDRSVKGLGIELDESLLAKYQVPDLSWDNVTVHQLQDRTADTKS

Specific function: D-galactonate degradation; first step. D-galactonate degradation; third step. [C]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family [H]

Homologues:

Organism=Escherichia coli, GI48994953, Length=378, Percent_Identity=25.9259259259259, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013370
- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =5.5.1.7 [H]

Molecular weight: Translated: 44343; Mature: 44343

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITDLELHAVGIPRHTGFVNKHVIVKIHTDEGLTGIGEMSDFSHLPLYSVDLHDLKQGL
CCCEEEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEECCHHHHHHHH
LSILLGQNPFDLMKINKELTDNFPETMYYYEKGSFIRNGIDNALHDLCAKYLDISVSDFL
HHHHHCCCCHHHHHHCHHHHCCCCHHEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
GGRVKEKIKVCYPIFRHRFSEEVESNLDVVRQKLEQGFDVFRLYVGKNLDADEEFLSRVK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHH
EEFGSRVRIKSYDFSHLLNWKDAHRAIKRLTKYDLGLEMIESPAPRNDFDGLYQLRLKTD
HHHCCEEEEEECCHHHHCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCEEEEEEECC
YPISEHVWSFKQQQEMIKKDAIDIFNISPVFIGGLTSAKKAAYAAEVASKDVVLGTTQEL
CCHHHHHHHHHHHHHHHHHHCCCEEECCHHEECCCCHHHHHHHHHHHCCCCEEEECCCHH
SVGTAAMAHLGCSLTNINHTSDPTGPELYVGDVVKNRVTYKDGYLYAPDRSVKGLGIELD
HHHHHHHHHHCCEEECCCCCCCCCCCCEEEHHHHHCCEEECCCEEECCCCCCCCCCEECC
ESLLAKYQVPDLSWDNVTVHQLQDRTADTKS
HHHHHHCCCCCCCCCCEEHHHHHCCCCCCCC
>Mature Secondary Structure
MKITDLELHAVGIPRHTGFVNKHVIVKIHTDEGLTGIGEMSDFSHLPLYSVDLHDLKQGL
CCCEEEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEECCHHHHHHHH
LSILLGQNPFDLMKINKELTDNFPETMYYYEKGSFIRNGIDNALHDLCAKYLDISVSDFL
HHHHHCCCCHHHHHHCHHHHCCCCHHEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
GGRVKEKIKVCYPIFRHRFSEEVESNLDVVRQKLEQGFDVFRLYVGKNLDADEEFLSRVK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHH
EEFGSRVRIKSYDFSHLLNWKDAHRAIKRLTKYDLGLEMIESPAPRNDFDGLYQLRLKTD
HHHCCEEEEEECCHHHHCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCEEEEEEECC
YPISEHVWSFKQQQEMIKKDAIDIFNISPVFIGGLTSAKKAAYAAEVASKDVVLGTTQEL
CCHHHHHHHHHHHHHHHHHHCCCEEECCHHEECCCCHHHHHHHHHHHCCCCEEEECCCHH
SVGTAAMAHLGCSLTNINHTSDPTGPELYVGDVVKNRVTYKDGYLYAPDRSVKGLGIELD
HHHHHHHHHHCCEEECCCCCCCCCCCCEEEHHHHHCCEEECCCEEECCCCCCCCCCEECC
ESLLAKYQVPDLSWDNVTVHQLQDRTADTKS
HHHHHHCCCCCCCCCCEEHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157603 [H]