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The map label for this gene is penP [H]

Identifier: 23100248

GI number: 23100248

Start: 2871462

End: 2872376

Strand: Reverse

Name: penP [H]

Synonym: OB2793

Alternate gene names: 23100248

Gene position: 2872376-2871462 (Counterclockwise)

Preceding gene: 23100249

Following gene: 23100247

Centisome position: 79.12

GC content: 38.47

Gene sequence:

>915_bases
ATGATACGTATTTTAAAAAGAAGTAGCTTTATATTACTATTTATGGTAGTTGGAATTGTATTAATGGCTTGTTCGAACGA
AGCTGAAAGTAAAGAAGGGATTCCAGAAGAAAACAATGGGGAATTAAATAAAGGTAGTGAGGATTTAAAAAAATTAGAAG
AAGAATTTGATGTGAGGCTAGGTGTGTATGCCATAGATACAGGAGCAGATAAGGAAATTAGCTATCGAGAAAATGAGCGG
TTTGCCTACACTTCTACATTTAAACCATTGGCTGTTGGGGCCGTCCTCCAAACGAAGTCTGATGAAGAATTAGAAGAAAC
TATTACATATAGCGAAGAAGATTTGGTTACGTATTCACCTATTACCGAGCAACATGTGGATGAAGGTATGACCCTTGTAG
AAATTGCTGATGCTGCAATTCGATATAGCGATAATACTGCTGGAAACCTCCTTTTAGAAGCTATGGGTGGTCCAGATGAA
TTAGAGACTATTTTAAGGGATATTGGTGATGAAACAATTGAAATGGATCGTTATGAAACAGAGCTAAATGAAGCAAAACC
AGGTGATATTCGTGATACAAGTACGGCGAAAGCAATGGCAACAACGCTTCAACAATATGTATTAGAAGATGTGCTAGATG
CAGATAGAAGAGAAGTTCTCACAAACATGCTTATTAACAATACGACAGGTGATGCGCTAATTCGTGCCGGTGTACCTGAT
GGTTGGACTGTTGGTGATAAGACAGGAGCAGGAGGATATGGAACGAGAAATGACATTGGTATCATTTGGCCAGAAGGTGA
CGAGGAGCCAATTGTTATTGCGATCATGTCTAGTCGCGATGAAGAAGATGCAGATTATGATGATAAATTAATAGAAAAAG
CGACGGAGATCGTGCTGCAGGAATTGAGAAATTAA

Upstream 100 bases:

>100_bases
GTGAAAATGTAATGGAGCTATAGATTTGAAATTACAAAAAGCTGAGATTCTAATAGGGTCACAGCTTTTTGTAATCTAGT
GATTGGAAGGAGGAAACTCG

Downstream 100 bases:

>100_bases
TAACAGGAATAAAATTCAGTATATTTTGACGGGGATGGAACTATTGGTACAATAATATAAAAGCAATTTCCCTTTAGAGA
AGGAGGAGAAAAACATTATG

Product: beta-lactamase

Products: NA

Alternate protein names: Penicillinase [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MIRILKRSSFILLFMVVGIVLMACSNEAESKEGIPEENNGELNKGSEDLKKLEEEFDVRLGVYAIDTGADKEISYRENER
FAYTSTFKPLAVGAVLQTKSDEELEETITYSEEDLVTYSPITEQHVDEGMTLVEIADAAIRYSDNTAGNLLLEAMGGPDE
LETILRDIGDETIEMDRYETELNEAKPGDIRDTSTAKAMATTLQQYVLEDVLDADRREVLTNMLINNTTGDALIRAGVPD
GWTVGDKTGAGGYGTRNDIGIIWPEGDEEPIVIAIMSSRDEEDADYDDKLIEKATEIVLQELRN

Sequences:

>Translated_304_residues
MIRILKRSSFILLFMVVGIVLMACSNEAESKEGIPEENNGELNKGSEDLKKLEEEFDVRLGVYAIDTGADKEISYRENER
FAYTSTFKPLAVGAVLQTKSDEELEETITYSEEDLVTYSPITEQHVDEGMTLVEIADAAIRYSDNTAGNLLLEAMGGPDE
LETILRDIGDETIEMDRYETELNEAKPGDIRDTSTAKAMATTLQQYVLEDVLDADRREVLTNMLINNTTGDALIRAGVPD
GWTVGDKTGAGGYGTRNDIGIIWPEGDEEPIVIAIMSSRDEEDADYDDKLIEKATEIVLQELRN
>Mature_304_residues
MIRILKRSSFILLFMVVGIVLMACSNEAESKEGIPEENNGELNKGSEDLKKLEEEFDVRLGVYAIDTGADKEISYRENER
FAYTSTFKPLAVGAVLQTKSDEELEETITYSEEDLVTYSPITEQHVDEGMTLVEIADAAIRYSDNTAGNLLLEAMGGPDE
LETILRDIGDETIEMDRYETELNEAKPGDIRDTSTAKAMATTLQQYVLEDVLDADRREVLTNMLINNTTGDALIRAGVPD
GWTVGDKTGAGGYGTRNDIGIIWPEGDEEPIVIAIMSSRDEEDADYDDKLIEKATEIVLQELRN

Specific function: This protein is a beta-lactamase with a substrate specificity for penicillins [H]

COG id: COG2367

COG function: function code V; Beta-lactamase class A

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-A beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466
- InterPro:   IPR000871 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 33752; Mature: 33752

Theoretical pI: Translated: 3.90; Mature: 3.90

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00146 BETA_LACTAMASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRILKRSSFILLFMVVGIVLMACSNEAESKEGIPEENNGELNKGSEDLKKLEEEFDVRL
CEEEEECCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCEE
GVYAIDTGADKEISYRENERFAYTSTFKPLAVGAVLQTKSDEELEETITYSEEDLVTYSP
EEEEEECCCCCCCCCCCCCCEEEECCCCHHHHHHHHHCCCHHHHHHHHCCCCCCEEEECC
ITEQHVDEGMTLVEIADAAIRYSDNTAGNLLLEAMGGPDELETILRDIGDETIEMDRYET
CHHHHHHCCCHHHHHHHHHHEECCCCCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHH
ELNEAKPGDIRDTSTAKAMATTLQQYVLEDVLDADRREVLTNMLINNTTGDALIRAGVPD
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEECCCCC
GWTVGDKTGAGGYGTRNDIGIIWPEGDEEPIVIAIMSSRDEEDADYDDKLIEKATEIVLQ
CCCCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
ELRN
HHCC
>Mature Secondary Structure
MIRILKRSSFILLFMVVGIVLMACSNEAESKEGIPEENNGELNKGSEDLKKLEEEFDVRL
CEEEEECCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCEE
GVYAIDTGADKEISYRENERFAYTSTFKPLAVGAVLQTKSDEELEETITYSEEDLVTYSP
EEEEEECCCCCCCCCCCCCCEEEECCCCHHHHHHHHHCCCHHHHHHHHCCCCCCEEEECC
ITEQHVDEGMTLVEIADAAIRYSDNTAGNLLLEAMGGPDELETILRDIGDETIEMDRYET
CHHHHHHCCCHHHHHHHHHHEECCCCCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHH
ELNEAKPGDIRDTSTAKAMATTLQQYVLEDVLDADRREVLTNMLINNTTGDALIRAGVPD
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEECCCCC
GWTVGDKTGAGGYGTRNDIGIIWPEGDEEPIVIAIMSSRDEEDADYDDKLIEKATEIVLQ
CCCCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
ELRN
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 10658653 [H]