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The map label for this gene is katA [H]

Identifier: 23100237

GI number: 23100237

Start: 2858942

End: 2860399

Strand: Reverse

Name: katA [H]

Synonym: OB2782

Alternate gene names: 23100237

Gene position: 2860399-2858942 (Counterclockwise)

Preceding gene: 23100238

Following gene: 23100234

Centisome position: 78.79

GC content: 37.52

Gene sequence:

>1458_bases
ATGACTAAAGGAAATAACGATGAGCAGAATAATTCTCGTAATTATTCACAAGGGTTTGGGAGTCAAGGACTACATGGATA
TCCAGGGAATGCGAGCGATAAATCCCATGCGAATCCCGCTGCTTTTAACTGGAATATTGATCTTCCAGCAGAAATTCATT
CACAGACGGTTGGAAAACGTGGTCCAATTTTAAAACAGGACAATATCGAGCATGAAACATTACAGACATTTATTCATGAA
AAGATTACCGAAAGACCAGTTCATGTAAAAGGTTGGGGGGCGTTTGGTTATTTTGAAACATTGTATTCTATGAGCGACTA
TACAACTTTATCTTTTCTACAGATACCAGGTACACAAGTGCCAGTATTTGTGCGATTCTCCTTAGCAGTCAGTACGAAGG
GAACGCCTGATACTTCAAGAAATGTACGAGGATTTGCGACTAAATTTTACAGTGAAGATGGTATATTTGATTTGATCTGC
AATCATATTCCTGTTTTTTCTGTTCGCGACACCATTCGTTTTCCAGAAGCGATTAAAGCATTTTTACCATCTCCAGTAAA
TAACTTAATCGATCCGACACGCTATTGGAACTTTGTAGCACGCGCACCTGAATCACTTCTCTTTACACTACTTGTTTATT
CTAATCTTGGCACAGTGAAAAGTTTACGTCATTTGCCTGGGCATAGTGTAAATACCTATGTATGGAAAAATGCAGAAGGA
AAACGGTATTTTATTAAATATACGTGGGCACCGATAGCCGGAGAGGAATATATTCGTAATGAAGAAGCGGTTAAATTAGC
TGGTGAAAATCCAGATATTGCAGGGCAAGATTTACATGATGCAATTGAAAGAGGGGAGCCAGTCGAATATGGATTATATA
TACAGATTATGGATCCAAAAGATGCTGCCAGTTTACCCTATGATCCATTAGATGATACGAAGTTATGGGATCAACAACAA
TTTCCTTTTAAACCAGTAGGAGTTATGAAATTAAATAAAAATCCAGACAATTATATGGAACAGGTAGAGAAAGCAGCATT
TTCGCCTACGAATTTATTAGAAGGTGTTGAGCTTTCGGATGATAAGATGCTGCAAGGAAGAGCTAATATATATTCTGATT
CACAGCGTTATCGTATTGGTCCTGATTTTCGTAATGTTCCAGTAAATAATCAATCTAATTGGTGGCCAGGTGACTTAGTG
ACAAGCGGTGATGGTCGATTTGTTGAAGGGGAGCTACAGCGGTCAGATATTGAAAAACAAGATGATTTTACACAACCCGG
ACTTTTTTATGAATCATTGTCAGAAGAAGATAAGGAAGATTTAATAACTAATATGGCGGAAGGACTTTCGGTTGTTTCTA
ATGATGTATTTAACACTGTCCATGGCTATATACAGGAAGCATCTAGAGATTTAGCGAACAGATTGAATAAAACTGTAATA
CTGAAGCGAAAAAAATAG

Upstream 100 bases:

>100_bases
TATAAATATTGCAGCAGTTGATCTCATACGGTTACGTCCAGGACATACGGTGGTAAACGGACGTTTGCGCTTTGATCTTG
GTGTGATAGGAGGTTTGACC

Downstream 100 bases:

>100_bases
ATTAAAATGAAAAACCGGTTGCTTCTCTAAAGGAAAAAGCATCCGGTATATTTTCTTTACGTATAAAATCCTTCATTGGA
AGTAACGAAAGGTAGTACAT

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 484

Protein sequence:

>485_residues
MTKGNNDEQNNSRNYSQGFGSQGLHGYPGNASDKSHANPAAFNWNIDLPAEIHSQTVGKRGPILKQDNIEHETLQTFIHE
KITERPVHVKGWGAFGYFETLYSMSDYTTLSFLQIPGTQVPVFVRFSLAVSTKGTPDTSRNVRGFATKFYSEDGIFDLIC
NHIPVFSVRDTIRFPEAIKAFLPSPVNNLIDPTRYWNFVARAPESLLFTLLVYSNLGTVKSLRHLPGHSVNTYVWKNAEG
KRYFIKYTWAPIAGEEYIRNEEAVKLAGENPDIAGQDLHDAIERGEPVEYGLYIQIMDPKDAASLPYDPLDDTKLWDQQQ
FPFKPVGVMKLNKNPDNYMEQVEKAAFSPTNLLEGVELSDDKMLQGRANIYSDSQRYRIGPDFRNVPVNNQSNWWPGDLV
TSGDGRFVEGELQRSDIEKQDDFTQPGLFYESLSEEDKEDLITNMAEGLSVVSNDVFNTVHGYIQEASRDLANRLNKTVI
LKRKK

Sequences:

>Translated_485_residues
MTKGNNDEQNNSRNYSQGFGSQGLHGYPGNASDKSHANPAAFNWNIDLPAEIHSQTVGKRGPILKQDNIEHETLQTFIHE
KITERPVHVKGWGAFGYFETLYSMSDYTTLSFLQIPGTQVPVFVRFSLAVSTKGTPDTSRNVRGFATKFYSEDGIFDLIC
NHIPVFSVRDTIRFPEAIKAFLPSPVNNLIDPTRYWNFVARAPESLLFTLLVYSNLGTVKSLRHLPGHSVNTYVWKNAEG
KRYFIKYTWAPIAGEEYIRNEEAVKLAGENPDIAGQDLHDAIERGEPVEYGLYIQIMDPKDAASLPYDPLDDTKLWDQQQ
FPFKPVGVMKLNKNPDNYMEQVEKAAFSPTNLLEGVELSDDKMLQGRANIYSDSQRYRIGPDFRNVPVNNQSNWWPGDLV
TSGDGRFVEGELQRSDIEKQDDFTQPGLFYESLSEEDKEDLITNMAEGLSVVSNDVFNTVHGYIQEASRDLANRLNKTVI
LKRKK
>Mature_484_residues
TKGNNDEQNNSRNYSQGFGSQGLHGYPGNASDKSHANPAAFNWNIDLPAEIHSQTVGKRGPILKQDNIEHETLQTFIHEK
ITERPVHVKGWGAFGYFETLYSMSDYTTLSFLQIPGTQVPVFVRFSLAVSTKGTPDTSRNVRGFATKFYSEDGIFDLICN
HIPVFSVRDTIRFPEAIKAFLPSPVNNLIDPTRYWNFVARAPESLLFTLLVYSNLGTVKSLRHLPGHSVNTYVWKNAEGK
RYFIKYTWAPIAGEEYIRNEEAVKLAGENPDIAGQDLHDAIERGEPVEYGLYIQIMDPKDAASLPYDPLDDTKLWDQQQF
PFKPVGVMKLNKNPDNYMEQVEKAAFSPTNLLEGVELSDDKMLQGRANIYSDSQRYRIGPDFRNVPVNNQSNWWPGDLVT
SGDGRFVEGELQRSDIEKQDDFTQPGLFYESLSEEDKEDLITNMAEGLSVVSNDVFNTVHGYIQEASRDLANRLNKTVIL
KRKK

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=425, Percent_Identity=36.4705882352941, Blast_Score=275, Evalue=8e-74,
Organism=Escherichia coli, GI48994891, Length=352, Percent_Identity=39.2045454545455, Blast_Score=263, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI25147792, Length=458, Percent_Identity=32.9694323144105, Blast_Score=268, Evalue=6e-72,
Organism=Caenorhabditis elegans, GI25151141, Length=458, Percent_Identity=32.9694323144105, Blast_Score=267, Evalue=7e-72,
Organism=Caenorhabditis elegans, GI71998444, Length=460, Percent_Identity=32.8260869565217, Blast_Score=263, Evalue=2e-70,
Organism=Saccharomyces cerevisiae, GI6320462, Length=339, Percent_Identity=39.2330383480826, Blast_Score=249, Evalue=6e-67,
Organism=Saccharomyces cerevisiae, GI6321525, Length=373, Percent_Identity=34.3163538873995, Blast_Score=221, Evalue=2e-58,
Organism=Drosophila melanogaster, GI17981717, Length=336, Percent_Identity=40.7738095238095, Blast_Score=269, Evalue=3e-72,
Organism=Drosophila melanogaster, GI19920968, Length=335, Percent_Identity=39.7014925373134, Blast_Score=266, Evalue=2e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 54940; Mature: 54809

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKGNNDEQNNSRNYSQGFGSQGLHGYPGNASDKSHANPAAFNWNIDLPAEIHSQTVGKR
CCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHCCCC
GPILKQDNIEHETLQTFIHEKITERPVHVKGWGAFGYFETLYSMSDYTTLSFLQIPGTQV
CCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHCCCCCEEEEEECCCCCC
PVFVRFSLAVSTKGTPDTSRNVRGFATKFYSEDGIFDLICNHIPVFSVRDTIRFPEAIKA
EEEEEEEEEEECCCCCCCCCCCHHHHHHHHCCCCHHHHHHCCCCEEECHHHHCCHHHHHH
FLPSPVNNLIDPTRYWNFVARAPESLLFTLLVYSNLGTVKSLRHLPGHSVNTYVWKNAEG
HCCCCHHHHCCHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEECCCC
KRYFIKYTWAPIAGEEYIRNEEAVKLAGENPDIAGQDLHDAIERGEPVEYGLYIQIMDPK
CEEEEEEEECCCCCHHHHCCCCCEEECCCCCCCCCCHHHHHHHCCCCEEEEEEEEEECCC
DAASLPYDPLDDTKLWDQQQFPFKPVGVMKLNKNPDNYMEQVEKAAFSPTNLLEGVELSD
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCHHHHHCCCCCCC
DKMLQGRANIYSDSQRYRIGPDFRNVPVNNQSNWWPGDLVTSGDGRFVEGELQRSDIEKQ
CHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEECCCCCEEECHHHHHCCCHH
DDFTQPGLFYESLSEEDKEDLITNMAEGLSVVSNDVFNTVHGYIQEASRDLANRLNKTVI
CCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LKRKK
EEECC
>Mature Secondary Structure 
TKGNNDEQNNSRNYSQGFGSQGLHGYPGNASDKSHANPAAFNWNIDLPAEIHSQTVGKR
CCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHCCCC
GPILKQDNIEHETLQTFIHEKITERPVHVKGWGAFGYFETLYSMSDYTTLSFLQIPGTQV
CCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHCCCCCEEEEEECCCCCC
PVFVRFSLAVSTKGTPDTSRNVRGFATKFYSEDGIFDLICNHIPVFSVRDTIRFPEAIKA
EEEEEEEEEEECCCCCCCCCCCHHHHHHHHCCCCHHHHHHCCCCEEECHHHHCCHHHHHH
FLPSPVNNLIDPTRYWNFVARAPESLLFTLLVYSNLGTVKSLRHLPGHSVNTYVWKNAEG
HCCCCHHHHCCHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEECCCC
KRYFIKYTWAPIAGEEYIRNEEAVKLAGENPDIAGQDLHDAIERGEPVEYGLYIQIMDPK
CEEEEEEEECCCCCHHHHCCCCCEEECCCCCCCCCCHHHHHHHCCCCEEEEEEEEEECCC
DAASLPYDPLDDTKLWDQQQFPFKPVGVMKLNKNPDNYMEQVEKAAFSPTNLLEGVELSD
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCHHHHHCCCCCCC
DKMLQGRANIYSDSQRYRIGPDFRNVPVNNQSNWWPGDLVTSGDGRFVEGELQRSDIEKQ
CHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEECCCCCEEECHHHHHCCCHH
DDFTQPGLFYESLSEEDKEDLITNMAEGLSVVSNDVFNTVHGYIQEASRDLANRLNKTVI
CCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LKRKK
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]