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The map label for this gene is aseR [H]

Identifier: 23099880

GI number: 23099880

Start: 2478329

End: 2478676

Strand: Reverse

Name: aseR [H]

Synonym: OB2425

Alternate gene names: 23099880

Gene position: 2478676-2478329 (Counterclockwise)

Preceding gene: 23099881

Following gene: 23099879

Centisome position: 68.27

GC content: 31.32

Gene sequence:

>348_bases
ATGGTTCAAAGTCAAACTAGATACGAATCTCAAGAATTAACAGAGTTACTGAGGATAATGAGTGATCCTACTCGTCTTTT
AATGGCATACTTTTTACAAAGTAAAACATATTGCGTATGTGAATTTGTTGAAATGTTTGAAATGACTCAACCGGCAATTA
GCCAGCACATACGTAAATTAAAACGAATGGATTTAATTACGGAAACGAGAAAAGGCCAGTGGAGATATTTTACAATAAAC
GATCAATCACCTTATTATTCATTGGTTCAACAGATTCTCAATACTATTAATCCAGAAGATACAAAAGTAAAAAGTATATT
GTTAAAAGAAAAACCTATGGAATGTTAG

Upstream 100 bases:

>100_bases
AGATAAACCAGCAAAACATTAAAATCCGCGAAAGTCACCAAACATAAGCATTGACTTATATAAGCAAATGCTTATATAAT
ATCTCAAGGAGGCGGTAACT

Downstream 100 bases:

>100_bases
GGAGGTATTTAGATTGTCATCAGTGTTTATTACATCAAGTATATTTTTACTTACGCTCATATTAGTGATATGGCAACCAA
AGAATTTAAATATCGGCTGG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 115; Mature: 115

Protein sequence:

>115_residues
MVQSQTRYESQELTELLRIMSDPTRLLMAYFLQSKTYCVCEFVEMFEMTQPAISQHIRKLKRMDLITETRKGQWRYFTIN
DQSPYYSLVQQILNTINPEDTKVKSILLKEKPMEC

Sequences:

>Translated_115_residues
MVQSQTRYESQELTELLRIMSDPTRLLMAYFLQSKTYCVCEFVEMFEMTQPAISQHIRKLKRMDLITETRKGQWRYFTIN
DQSPYYSLVQQILNTINPEDTKVKSILLKEKPMEC
>Mature_115_residues
MVQSQTRYESQELTELLRIMSDPTRLLMAYFLQSKTYCVCEFVEMFEMTQPAISQHIRKLKRMDLITETRKGQWRYFTIN
DQSPYYSLVQQILNTINPEDTKVKSILLKEKPMEC

Specific function: Metal-responsive transcriptional regulator that represses transcription of the aseR-ydfA operon by binding specifically to its promoter. Binding of arsenite or antimonite causes the repressor to dissociate from the DNA [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 13782; Mature: 13782

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
8.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
8.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQSQTRYESQELTELLRIMSDPTRLLMAYFLQSKTYCVCEFVEMFEMTQPAISQHIRKL
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHH
KRMDLITETRKGQWRYFTINDQSPYYSLVQQILNTINPEDTKVKSILLKEKPMEC
HHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MVQSQTRYESQELTELLRIMSDPTRLLMAYFLQSKTYCVCEFVEMFEMTQPAISQHIRKL
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHH
KRMDLITETRKGQWRYFTINDQSPYYSLVQQILNTINPEDTKVKSILLKEKPMEC
HHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]