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The map label for this gene is lytH [H]

Identifier: 23099822

GI number: 23099822

Start: 2416472

End: 2417440

Strand: Direct

Name: lytH [H]

Synonym: OB2367

Alternate gene names: 23099822

Gene position: 2416472-2417440 (Clockwise)

Preceding gene: 23099821

Following gene: 28563936

Centisome position: 66.56

GC content: 36.64

Gene sequence:

>969_bases
GTGAACCCAAAACAAGTGCTCATGCTAACGGGATTCATCCTATTTATTACTACTTTCCCATTAACCATTCTGGCTGAGGA
TAATCAAGAGAACGATATTTATGAACAACGGATGGCTCTTTTTAAAAAAACAGAAGCTTTAACGCAAATTCCATGGTATT
ATTTTGCGGCAATCGATAACTACGAACGAAATATAACTAATAGTGATGAACCAGAGAAAGTAATATCAATTGAATTTGCC
GAGGAAATTTGGTACGGATTAGGCAACGCTGCTAAAGCATCTGAAAATGAAATAATTCAACAGTTTGGTGGCATTGGAAA
AGATGGTAATGGTGACGGTAAGGCACAAATAAAAAATGAAGAAGATATTTTATATTCCATGGGTATGGTAATTCAAGAAT
ATGGAATGAATGAAGATGATATTAAAATTGCTCTTTGGGAACATTATAAAAGAGATTTAACGGTGCAAACCATTATGAAT
ACATCTAAAGTATTTAAGAAATTTGGTCACGTTCACCTCACCAATCGAGCATTTCCAGTAGACACAGATTATAATTATAG
CTACCGTAATACGTGGGGGGATCGACGTGGATTCGGTGGTTTGCGAATACATGAAGGGACTGATATTTTTGCCTCTTACG
GGGTTCCAGTTCAATCAACAACATACGGCGTAGTTGAAATGATGGGATGGAATCTTTATGGTGGTTGGAGAATAGGAATT
AGAGACATCTACAATATTTATCATTATTATGCACATATGAATGGATATAGTGACGATTTAAAAGTAGGTCAAGTTGTAGA
GCCAGGTGATGTTATCGGTAGCGTCGGATCCACAGGATACGGCCCACCAGGAACTTCTGGAAAATTTCCACCACATTTGC
ATTATGGAATGTATAAAGATAATGGATACAGCGAATTCTCATTCGATCCTTATCCATACTTAAAAAAGTGGGAGCGAATG
TCTAATTAA

Upstream 100 bases:

>100_bases
GATTTAAGATCAAAAGTGAAAATCGGCATATAGAAACACATCGATTTTTATACGTGGTTCTTGATGTGAAGATTATTTGG
GGTATAAAGGAGGTGACAAC

Downstream 100 bases:

>100_bases
ACGTTTAAGCTTATTCCAATGTGGTTAGAATAAAAAAGTTTTTTTAATAACATTCAAGCTGTAGAATTGATGTATAACGA
CTAGGTTATCCAAGATTTCA

Product: hypothetical protein

Products: NA

Alternate protein names: Peptidoglycan hydrolase; Sporulation-specific endopeptidase [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MNPKQVLMLTGFILFITTFPLTILAEDNQENDIYEQRMALFKKTEALTQIPWYYFAAIDNYERNITNSDEPEKVISIEFA
EEIWYGLGNAAKASENEIIQQFGGIGKDGNGDGKAQIKNEEDILYSMGMVIQEYGMNEDDIKIALWEHYKRDLTVQTIMN
TSKVFKKFGHVHLTNRAFPVDTDYNYSYRNTWGDRRGFGGLRIHEGTDIFASYGVPVQSTTYGVVEMMGWNLYGGWRIGI
RDIYNIYHYYAHMNGYSDDLKVGQVVEPGDVIGSVGSTGYGPPGTSGKFPPHLHYGMYKDNGYSEFSFDPYPYLKKWERM
SN

Sequences:

>Translated_322_residues
MNPKQVLMLTGFILFITTFPLTILAEDNQENDIYEQRMALFKKTEALTQIPWYYFAAIDNYERNITNSDEPEKVISIEFA
EEIWYGLGNAAKASENEIIQQFGGIGKDGNGDGKAQIKNEEDILYSMGMVIQEYGMNEDDIKIALWEHYKRDLTVQTIMN
TSKVFKKFGHVHLTNRAFPVDTDYNYSYRNTWGDRRGFGGLRIHEGTDIFASYGVPVQSTTYGVVEMMGWNLYGGWRIGI
RDIYNIYHYYAHMNGYSDDLKVGQVVEPGDVIGSVGSTGYGPPGTSGKFPPHLHYGMYKDNGYSEFSFDPYPYLKKWERM
SN
>Mature_322_residues
MNPKQVLMLTGFILFITTFPLTILAEDNQENDIYEQRMALFKKTEALTQIPWYYFAAIDNYERNITNSDEPEKVISIEFA
EEIWYGLGNAAKASENEIIQQFGGIGKDGNGDGKAQIKNEEDILYSMGMVIQEYGMNEDDIKIALWEHYKRDLTVQTIMN
TSKVFKKFGHVHLTNRAFPVDTDYNYSYRNTWGDRRGFGGLRIHEGTDIFASYGVPVQSTTYGVVEMMGWNLYGGWRIGI
RDIYNIYHYYAHMNGYSDDLKVGQVVEPGDVIGSVGSTGYGPPGTSGKFPPHLHYGMYKDNGYSEFSFDPYPYLKKWERM
SN

Specific function: L-Ala--D-Glu endopeptidase involved in production of single L-alanine side chains from tetrapeptides in the spore cortex peptidoglycan. Therefore, is required for the endospore cortex maturation [H]

COG id: COG0739

COG function: function code M; Membrane proteins related to metalloendopeptidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M23B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR016047 [H]

Pfam domain/function: PF01551 Peptidase_M23 [H]

EC number: NA

Molecular weight: Translated: 36915; Mature: 36915

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPKQVLMLTGFILFITTFPLTILAEDNQENDIYEQRMALFKKTEALTQIPWYYFAAIDN
CCCHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECC
YERNITNSDEPEKVISIEFAEEIWYGLGNAAKASENEIIQQFGGIGKDGNGDGKAQIKNE
HHCCCCCCCCCCCEEEEEEHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEECCC
EDILYSMGMVIQEYGMNEDDIKIALWEHYKRDLTVQTIMNTSKVFKKFGHVHLTNRAFPV
HHHHHHHHHHHHHHCCCCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHCCEEECCCEECC
DTDYNYSYRNTWGDRRGFGGLRIHEGTDIFASYGVPVQSTTYGVVEMMGWNLYGGWRIGI
CCCCCCCHHCCCCCCCCCCCEEEECCCCEEEECCCCCCCCHHHHHHHHCCCEECCEEEHH
RDIYNIYHYYAHMNGYSDDLKVGQVVEPGDVIGSVGSTGYGPPGTSGKFPPHLHYGMYKD
HHHHHHHHHHHHCCCCCCCCCCCCEECCHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEC
NGYSEFSFDPYPYLKKWERMSN
CCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MNPKQVLMLTGFILFITTFPLTILAEDNQENDIYEQRMALFKKTEALTQIPWYYFAAIDN
CCCHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECC
YERNITNSDEPEKVISIEFAEEIWYGLGNAAKASENEIIQQFGGIGKDGNGDGKAQIKNE
HHCCCCCCCCCCCEEEEEEHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEECCC
EDILYSMGMVIQEYGMNEDDIKIALWEHYKRDLTVQTIMNTSKVFKKFGHVHLTNRAFPV
HHHHHHHHHHHHHHCCCCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHCCEEECCCEECC
DTDYNYSYRNTWGDRRGFGGLRIHEGTDIFASYGVPVQSTTYGVVEMMGWNLYGGWRIGI
CCCCCCCHHCCCCCCCCCCCEEEECCCCEEEECCCCCCCCHHHHHHHHCCCEECCEEEHH
RDIYNIYHYYAHMNGYSDDLKVGQVVEPGDVIGSVGSTGYGPPGTSGKFPPHLHYGMYKD
HHHHHHHHHHHHCCCCCCCCCCCCEECCHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEC
NGYSEFSFDPYPYLKKWERMSN
CCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12813075 [H]