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The map label for this gene is deoD

Identifier: 23099800

GI number: 23099800

Start: 2399590

End: 2400297

Strand: Direct

Name: deoD

Synonym: OB2345

Alternate gene names: 23099800

Gene position: 2399590-2400297 (Clockwise)

Preceding gene: 23099798

Following gene: 23099801

Centisome position: 66.09

GC content: 35.17

Gene sequence:

>708_bases
ATGAGTGTACATATTGGAGCAAAACAAGGAGAAATTGCAGATAAAATACTTTTACCCGGAGACCCGCTCCGCGCAAAATA
TATAGCAGAGACTTTTTTAGAGGAACCAAAATTATATAACGAAGTTAGAGGTATGTATGGTTACACTGGTACTTACAAAG
GTGAACGTGTTTCTGTTCAAGGAACTGGTATGGGTGTACCATCTATTTCAATCTATGTAAACGAATTAATTCAAAGCTAT
GATGTGAAGAAATTAATTCGAGTAGGTACATGCGGTGCTATTCAAAAAGATGTCAACGTTCGTGATGTTATTTTAGCACA
AGGAGCTACGACAGATTCTCAAATGAATCGCCTTATCTTCAACGGAATTGATTATGCACCAATTGCAGATTTTGAACTAC
TAAAAAATGCATATGACGCCGGAGTAGATAAAGGACTTCATTTACGAGTAGGAAATGTATTCACAAGTGATACATTTTAT
CGTGATAATGCACAGCAAGTAAATGAATTACTGGCTAAATATCAAGTACTTGCCATTGAAATGGAATCTACAGCGCTATA
TACATTAGCAGCTAAATATGGTAGACAAGCACTTTCTGTATTAACGGTTTCCGATCATATTATAACTGGTGAAGAAACTA
CTGCTGAGGAACGACAAACAACTTTTAATGACATGATGGAAATTGCTTTAGATACTATTATAAAATAA

Upstream 100 bases:

>100_bases
CCGATAACTATATTTTTATTTATATGAATTTAATTGTTTTTCAAATACGATTATGGTAACTTTAATCTAGAAATAGCAAC
TAGTTCAAGGAGGCTGTAAA

Downstream 100 bases:

>100_bases
ACGATTGCCCAGCTTATTCTTGCTGGGTATTTTTTTATTTGTATTGTCAACCTGTTAAAATATTTAGTTGACAAAATATA
TGAATCTATTTATAGTAAAG

Product: purine nucleoside phosphorylase

Products: NA

Alternate protein names: PNP

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MSVHIGAKQGEIADKILLPGDPLRAKYIAETFLEEPKLYNEVRGMYGYTGTYKGERVSVQGTGMGVPSISIYVNELIQSY
DVKKLIRVGTCGAIQKDVNVRDVILAQGATTDSQMNRLIFNGIDYAPIADFELLKNAYDAGVDKGLHLRVGNVFTSDTFY
RDNAQQVNELLAKYQVLAIEMESTALYTLAAKYGRQALSVLTVSDHIITGEETTAEERQTTFNDMMEIALDTIIK

Sequences:

>Translated_235_residues
MSVHIGAKQGEIADKILLPGDPLRAKYIAETFLEEPKLYNEVRGMYGYTGTYKGERVSVQGTGMGVPSISIYVNELIQSY
DVKKLIRVGTCGAIQKDVNVRDVILAQGATTDSQMNRLIFNGIDYAPIADFELLKNAYDAGVDKGLHLRVGNVFTSDTFY
RDNAQQVNELLAKYQVLAIEMESTALYTLAAKYGRQALSVLTVSDHIITGEETTAEERQTTFNDMMEIALDTIIK
>Mature_234_residues
SVHIGAKQGEIADKILLPGDPLRAKYIAETFLEEPKLYNEVRGMYGYTGTYKGERVSVQGTGMGVPSISIYVNELIQSYD
VKKLIRVGTCGAIQKDVNVRDVILAQGATTDSQMNRLIFNGIDYAPIADFELLKNAYDAGVDKGLHLRVGNVFTSDTFYR
DNAQQVNELLAKYQVLAIEMESTALYTLAAKYGRQALSVLTVSDHIITGEETTAEERQTTFNDMMEIALDTIIK

Specific function: Cleavage Of Guanosine Or Inosine To Respective Bases And Sugar-1-Phosphate Molecules. [C]

COG id: COG0813

COG function: function code F; Purine-nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family

Homologues:

Organism=Escherichia coli, GI1790844, Length=231, Percent_Identity=54.1125541125541, Blast_Score=274, Evalue=4e-75,
Organism=Escherichia coli, GI1790265, Length=209, Percent_Identity=30.1435406698565, Blast_Score=85, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOD_OCEIH (Q8ENY0)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_693266.1
- ProteinModelPortal:   Q8ENY0
- SMR:   Q8ENY0
- GeneID:   1016148
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB2345
- NMPDR:   fig|221109.1.peg.2342
- HOGENOM:   HBG617197
- OMA:   SFETHAF
- ProtClustDB:   PRK05819
- BioCyc:   OIHE221109:OB2345-MONOMER
- BRENDA:   2.4.2.1
- HAMAP:   MF_01627
- InterPro:   IPR004402
- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- PANTHER:   PTHR21234
- TIGRFAMs:   TIGR00107

Pfam domain/function: PF01048 PNP_UDP_1

EC number: =2.4.2.1

Molecular weight: Translated: 26019; Mature: 25888

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVHIGAKQGEIADKILLPGDPLRAKYIAETFLEEPKLYNEVRGMYGYTGTYKGERVSVQ
CEEECCCCCCCCCCEEECCCCCHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCEEEEE
GTGMGVPSISIYVNELIQSYDVKKLIRVGTCGAIQKDVNVRDVILAQGATTDSQMNRLIF
ECCCCCCHHHHHHHHHHHHHCHHHHHHHCCCCCHHCCCCHHHEEEECCCCCHHHHHHHHH
NGIDYAPIADFELLKNAYDAGVDKGLHLRVGNVFTSDTFYRDNAQQVNELLAKYQVLAIE
CCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCEEECCCEECCCHHHHHHHHHHHEEEEEE
MESTALYTLAAKYGRQALSVLTVSDHIITGEETTAEERQTTFNDMMEIALDTIIK
ECCHHHHHHHHHHHHHHHHEEEECCEEECCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVHIGAKQGEIADKILLPGDPLRAKYIAETFLEEPKLYNEVRGMYGYTGTYKGERVSVQ
EEECCCCCCCCCCEEECCCCCHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCEEEEE
GTGMGVPSISIYVNELIQSYDVKKLIRVGTCGAIQKDVNVRDVILAQGATTDSQMNRLIF
ECCCCCCHHHHHHHHHHHHHCHHHHHHHCCCCCHHCCCCHHHEEEECCCCCHHHHHHHHH
NGIDYAPIADFELLKNAYDAGVDKGLHLRVGNVFTSDTFYRDNAQQVNELLAKYQVLAIE
CCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCEEECCCEECCCHHHHHHHHHHHEEEEEE
MESTALYTLAAKYGRQALSVLTVSDHIITGEETTAEERQTTFNDMMEIALDTIIK
ECCHHHHHHHHHHHHHHHHEEEECCEEECCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376