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The map label for this gene is yraN [H]

Identifier: 23099725

GI number: 23099725

Start: 2313398

End: 2314267

Strand: Direct

Name: yraN [H]

Synonym: OB2270

Alternate gene names: 23099725

Gene position: 2313398-2314267 (Clockwise)

Preceding gene: 23099721

Following gene: 23099728

Centisome position: 63.72

GC content: 34.02

Gene sequence:

>870_bases
ATGCATCTACAGGATTGGGAAATGTTATCTACTTTATATGAGACAGAAAATATAACGCAGGCTGCCCATCAATTGTTTTT
AACACAGCCCACTCTTACATCACGAATAAAAAAATTAGAAGCATATTATGGCATACAAATTATTATGAGAAAACGTAGAG
GGATTGCATTTACTCCTGAGGGAGAACAATTGGCACATCATGCTCAACAAATGTTAAGAGAACAGAGAAAAATCGAGGAA
AAAATAGACAATATGAAAAATCAAGTTACAGGAACATTACGTGTAGGGGTTTCAAACTTTTTTGCATCCAATAAAATGCC
TAAACTGCTTCAATTATTTAAACAAGAATTTCCTGATGTAGAGTGCCAGGTAGTTACTGGATGGAGCAGCGAAATGCATC
GCTTGTTACTAAATCATGATGTACATATTAGTTTTATAAAAGGAAATTATCCATGGAAAGAGCGGAAACAATTATTGTAT
GAAGAAGAAATTTGCATCGCATCCCCTTGGGAATTTACTTGGGAACAGCTACCACAACTTCCTAGAATTGATTATTATAC
AGATGATCATATGCGAATGCTTGTTGATAATTGGTGGCATCAGCATTATACACAGAGTCCTAATATCACTATCCATGTGA
ATCAAGTTGAAACTTGCAAGGAAATGGTTGTACATGGCTTAGGATATGCAGTAATAGCTAATTTAGTAGTTAGAAATAAC
CCAGAATTAATTGTTAAACCAATCATAGATGAAGATAATGAACTAATTAAAAGACAGACATGGATGTATTACCCAGAAGA
TGCATTACAAATGAATGTTGTTCGTGCATTTGTTAATTTCATTCAGACGATTGATGTTAAGTCCTTATAG

Upstream 100 bases:

>100_bases
CTACCTATATTATAATATTGATTAGAAAATTAGAAAAATATATAATATTAATAAATAAACATAAAAAAAATCTATATCAT
ATTCTATAGGGGGATTATTA

Downstream 100 bases:

>100_bases
TATATTAATTATAATCAGACATAATAAGTCTATAAAAACAACCAAGATGAGACAATGCAAATCTGGATTTCTCAAAATGT
ATACATTTCGAGAAATCCTA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MHLQDWEMLSTLYETENITQAAHQLFLTQPTLTSRIKKLEAYYGIQIIMRKRRGIAFTPEGEQLAHHAQQMLREQRKIEE
KIDNMKNQVTGTLRVGVSNFFASNKMPKLLQLFKQEFPDVECQVVTGWSSEMHRLLLNHDVHISFIKGNYPWKERKQLLY
EEEICIASPWEFTWEQLPQLPRIDYYTDDHMRMLVDNWWHQHYTQSPNITIHVNQVETCKEMVVHGLGYAVIANLVVRNN
PELIVKPIIDEDNELIKRQTWMYYPEDALQMNVVRAFVNFIQTIDVKSL

Sequences:

>Translated_289_residues
MHLQDWEMLSTLYETENITQAAHQLFLTQPTLTSRIKKLEAYYGIQIIMRKRRGIAFTPEGEQLAHHAQQMLREQRKIEE
KIDNMKNQVTGTLRVGVSNFFASNKMPKLLQLFKQEFPDVECQVVTGWSSEMHRLLLNHDVHISFIKGNYPWKERKQLLY
EEEICIASPWEFTWEQLPQLPRIDYYTDDHMRMLVDNWWHQHYTQSPNITIHVNQVETCKEMVVHGLGYAVIANLVVRNN
PELIVKPIIDEDNELIKRQTWMYYPEDALQMNVVRAFVNFIQTIDVKSL
>Mature_289_residues
MHLQDWEMLSTLYETENITQAAHQLFLTQPTLTSRIKKLEAYYGIQIIMRKRRGIAFTPEGEQLAHHAQQMLREQRKIEE
KIDNMKNQVTGTLRVGVSNFFASNKMPKLLQLFKQEFPDVECQVVTGWSSEMHRLLLNHDVHISFIKGNYPWKERKQLLY
EEEICIASPWEFTWEQLPQLPRIDYYTDDHMRMLVDNWWHQHYTQSPNITIHVNQVETCKEMVVHGLGYAVIANLVVRNN
PELIVKPIIDEDNELIKRQTWMYYPEDALQMNVVRAFVNFIQTIDVKSL

Specific function: May Be An Accessory Regulatory Protein Within The Cys Regulon. [C]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788296, Length=228, Percent_Identity=23.6842105263158, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790399, Length=250, Percent_Identity=24, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788481, Length=296, Percent_Identity=20.6081081081081, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790208, Length=255, Percent_Identity=23.921568627451, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789204, Length=249, Percent_Identity=23.2931726907631, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788297, Length=251, Percent_Identity=22.3107569721116, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787806, Length=297, Percent_Identity=23.5690235690236, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789506, Length=151, Percent_Identity=24.5033112582781, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787601, Length=111, Percent_Identity=28.8288288288288, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1788887, Length=263, Percent_Identity=22.4334600760456, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI87082132, Length=177, Percent_Identity=29.3785310734463, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34315; Mature: 34315

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLQDWEMLSTLYETENITQAAHQLFLTQPTLTSRIKKLEAYYGIQIIMRKRRGIAFTPE
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCC
GEQLAHHAQQMLREQRKIEEKIDNMKNQVTGTLRVGVSNFFASNKMPKLLQLFKQEFPDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHCCCCHHHHHHHHHHCCCC
ECQVVTGWSSEMHRLLLNHDVHISFIKGNYPWKERKQLLYEEEICIASPWEFTWEQLPQL
EEEEEECCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHCCCEEECCCCHHHHHCCCC
PRIDYYTDDHMRMLVDNWWHQHYTQSPNITIHVNQVETCKEMVVHGLGYAVIANLVVRNN
CCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHCCHHHHHHHHHCCC
PELIVKPIIDEDNELIKRQTWMYYPEDALQMNVVRAFVNFIQTIDVKSL
CCEEEEECCCCCHHHHHHHHCEECCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MHLQDWEMLSTLYETENITQAAHQLFLTQPTLTSRIKKLEAYYGIQIIMRKRRGIAFTPE
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCC
GEQLAHHAQQMLREQRKIEEKIDNMKNQVTGTLRVGVSNFFASNKMPKLLQLFKQEFPDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHCCCCHHHHHHHHHHCCCC
ECQVVTGWSSEMHRLLLNHDVHISFIKGNYPWKERKQLLYEEEICIASPWEFTWEQLPQL
EEEEEECCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHCCCEEECCCCHHHHHCCCC
PRIDYYTDDHMRMLVDNWWHQHYTQSPNITIHVNQVETCKEMVVHGLGYAVIANLVVRNN
CCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHCCHHHHHHHHHCCC
PELIVKPIIDEDNELIKRQTWMYYPEDALQMNVVRAFVNFIQTIDVKSL
CCEEEEECCCCCHHHHHHHHCEECCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9141695; 9308178; 9384377 [H]