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The map label for this gene is appB [H]

Identifier: 23099716

GI number: 23099716

Start: 2302657

End: 2303625

Strand: Reverse

Name: appB [H]

Synonym: OB2261

Alternate gene names: 23099716

Gene position: 2303625-2302657 (Counterclockwise)

Preceding gene: 23099717

Following gene: 23099715

Centisome position: 63.45

GC content: 37.15

Gene sequence:

>969_bases
ATGACCAAATATATTATACGAAGAGTGCTAGTCTTTTTCCCAATGTTGTTAGCTCTAACTATAATTGTATTTACAATTGC
TCAATTAGCTCCTGGAGACGCTTTGACAGGGCAGCAACTTTCGGACCCAAATATAGATCCAGAAGTGTATGAAAAACAAA
GGGAAGCGCTAGGCTTAAATGATCCTATTCCTATTCGATATGGCAGGTGGATAGCAGATGTTGCACAAGGTGATCTAGGA
AATTCACTTGTATTTAATGGACGTTCTGTAATGGAATTAATTAAGGATAGGATAATGAATACAGTATACTTAGGAGTATT
TGCATTATTTATTACATTAGTTGTATCTATACCAATAGGTATTTATTCTGCTAGAAAGCCTTATTCGTTAATAGATTATG
CTGCTACAGGATTTGGATTTTTAGGACTAGCTATACCGAACTTCTTTTTTGGTTTAATGGCTATCTACTTTTTATCTATT
AACCTGGGATGGTTTCCTGCGCAAGGGACATTGTCGTCTCCTGGAGCAACAGGTTTTAGCGGTTTAGCTGATCGAATTCA
TCATATGATTCTACCGGGAATAACATTAGGACTAGCTGGTACGGCAACATACATGAGGTATATGCGATCCGAAGTATTGG
GTGTTTTAGGTAGTGATTATATTCGAACTGCAAGAGCGAAAGGGATGTCTGAGCGAAATGTTCTATATAAACATACACTT
CGAAATGCATTATTACCAATTGTGACTTTAATGGGATTTGAAATTGGAGTTCTACTTGGTGGCGCAGTCATTACGGAACA
AGTATTTCAATACCCTGGACTTGGGACGCTATTTCTTAGCTCTGTTACCAATCGTGACTATCCAGTTGTGATGGCAATTG
CTATGATTCTAGGTGTTTTAGTCTTAGTTGGAAACTTAGTTGCTGACATTATGTATAGTGTTATTGATCCTAGAATTCGT
TATGATTGA

Upstream 100 bases:

>100_bases
CATCTATGGTGGGTTTCTGAGTAATAGTATGGGAGCGTGCGTTAGATGGCGTATGCTCCCATCTATTTTTACTAGAAAGA
TACATTAAGGTGGGAATAAC

Downstream 100 bases:

>100_bases
GGTGAGTGAAAATGCAATCAATGCCACAGGAACCAGTACCTAATACTCCTAAAGAAGGTGTCATAGTCAAGAAAGAAAAA
AGTAAAAGCCCCTTTCAAAT

Product: oligopeptide ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MTKYIIRRVLVFFPMLLALTIIVFTIAQLAPGDALTGQQLSDPNIDPEVYEKQREALGLNDPIPIRYGRWIADVAQGDLG
NSLVFNGRSVMELIKDRIMNTVYLGVFALFITLVVSIPIGIYSARKPYSLIDYAATGFGFLGLAIPNFFFGLMAIYFLSI
NLGWFPAQGTLSSPGATGFSGLADRIHHMILPGITLGLAGTATYMRYMRSEVLGVLGSDYIRTARAKGMSERNVLYKHTL
RNALLPIVTLMGFEIGVLLGGAVITEQVFQYPGLGTLFLSSVTNRDYPVVMAIAMILGVLVLVGNLVADIMYSVIDPRIR
YD

Sequences:

>Translated_322_residues
MTKYIIRRVLVFFPMLLALTIIVFTIAQLAPGDALTGQQLSDPNIDPEVYEKQREALGLNDPIPIRYGRWIADVAQGDLG
NSLVFNGRSVMELIKDRIMNTVYLGVFALFITLVVSIPIGIYSARKPYSLIDYAATGFGFLGLAIPNFFFGLMAIYFLSI
NLGWFPAQGTLSSPGATGFSGLADRIHHMILPGITLGLAGTATYMRYMRSEVLGVLGSDYIRTARAKGMSERNVLYKHTL
RNALLPIVTLMGFEIGVLLGGAVITEQVFQYPGLGTLFLSSVTNRDYPVVMAIAMILGVLVLVGNLVADIMYSVIDPRIR
YD
>Mature_321_residues
TKYIIRRVLVFFPMLLALTIIVFTIAQLAPGDALTGQQLSDPNIDPEVYEKQREALGLNDPIPIRYGRWIADVAQGDLGN
SLVFNGRSVMELIKDRIMNTVYLGVFALFITLVVSIPIGIYSARKPYSLIDYAATGFGFLGLAIPNFFFGLMAIYFLSIN
LGWFPAQGTLSSPGATGFSGLADRIHHMILPGITLGLAGTATYMRYMRSEVLGVLGSDYIRTARAKGMSERNVLYKHTLR
NALLPIVTLMGFEIGVLLGGAVITEQVFQYPGLGTLFLSSVTNRDYPVVMAIAMILGVLVLVGNLVADIMYSVIDPRIRY
D

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=322, Percent_Identity=36.9565217391304, Blast_Score=221, Evalue=5e-59,
Organism=Escherichia coli, GI1789965, Length=344, Percent_Identity=36.046511627907, Blast_Score=216, Evalue=1e-57,
Organism=Escherichia coli, GI1789888, Length=321, Percent_Identity=34.2679127725857, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1787497, Length=321, Percent_Identity=34.2679127725857, Blast_Score=194, Evalue=5e-51,
Organism=Escherichia coli, GI1788504, Length=365, Percent_Identity=32.3287671232877, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI1787761, Length=320, Percent_Identity=34.375, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1787550, Length=266, Percent_Identity=31.5789473684211, Blast_Score=143, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35333; Mature: 35202

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKYIIRRVLVFFPMLLALTIIVFTIAQLAPGDALTGQQLSDPNIDPEVYEKQREALGLN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
DPIPIRYGRWIADVAQGDLGNSLVFNGRSVMELIKDRIMNTVYLGVFALFITLVVSIPIG
CCCCCCHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IYSARKPYSLIDYAATGFGFLGLAIPNFFFGLMAIYFLSINLGWFPAQGTLSSPGATGFS
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCHH
GLADRIHHMILPGITLGLAGTATYMRYMRSEVLGVLGSDYIRTARAKGMSERNVLYKHTL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
RNALLPIVTLMGFEIGVLLGGAVITEQVFQYPGLGTLFLSSVTNRDYPVVMAIAMILGVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHH
VLVGNLVADIMYSVIDPRIRYD
HHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TKYIIRRVLVFFPMLLALTIIVFTIAQLAPGDALTGQQLSDPNIDPEVYEKQREALGLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
DPIPIRYGRWIADVAQGDLGNSLVFNGRSVMELIKDRIMNTVYLGVFALFITLVVSIPIG
CCCCCCHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IYSARKPYSLIDYAATGFGFLGLAIPNFFFGLMAIYFLSINLGWFPAQGTLSSPGATGFS
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCHH
GLADRIHHMILPGITLGLAGTATYMRYMRSEVLGVLGSDYIRTARAKGMSERNVLYKHTL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
RNALLPIVTLMGFEIGVLLGGAVITEQVFQYPGLGTLFLSSVTNRDYPVVMAIAMILGVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHH
VLVGNLVADIMYSVIDPRIRYD
HHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]