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The map label for this gene is kdgK [H]

Identifier: 23099668

GI number: 23099668

Start: 2247568

End: 2248530

Strand: Direct

Name: kdgK [H]

Synonym: OB2213

Alternate gene names: 23099668

Gene position: 2247568-2248530 (Clockwise)

Preceding gene: 23099667

Following gene: 23099669

Centisome position: 61.91

GC content: 36.03

Gene sequence:

>963_bases
ATGAAAAGAATGGATGTTATTGGAATCGGAGAAACAATGGTATCACTAACCCCAGATAAATACGGTCTTATTAGGCAAAC
GTCCTCCTTTGAACCACGTGTTGCTGGTACAGAAACCAATACGTTAATTGGATTAAGCAGATTAGGTCACAATACTGGTT
TTATAAGTCGATTAGGAGAAGATGAATTGGGAGCAATGGTATTAAAAGAATTACGTGGAGAGAACGTAGATACGAAGTTA
ATAGACTTGGATCCCTATCATCAGACCGGATTATTTTTAAAAGAAATCATTAATGAGTCAGATGTTCATGTTTATTATTA
CCGTCAACATTCAGCAGCTAGCCAAATGACTCGAGAGTTACTTGATGAGAGTTATATTTCTTCCGCTTCTTATCTATTTA
TAACTGGAATTACTCCTGCGATTAGCGAAAGTTGTAAACAAACCATTTTCACAGCAATAAACATGGCAAAAAATAATGGG
GTGAAAATAGTATTCGATCCAAATATTCGTAAGAAACTTTGGTCCGAATCAGAAGCTAGACAAACATTAATCGAAATCTT
AAAGTTATCGGATATTATTCTACCGGGTATTAGTGAAGGACAATTTTTATTAGATAGTAATGACCCAGAAGAAATCGGTA
AAAAATGTGTAGATTTAGGTGCAGAGTTAGTTGTAGTAAAACTCGGTGAAAATGGAGCCTATTATTGTACAAGTGATCAT
GGGGATTATGTCCCCAGTTTTCCTGTAAAACAAGTGAGAGATCCTGTTGGTGCTGGAGATGCGTTTGCAGCTGGTTTATT
ATCTGGACTAATTGATGAATTATCTATTGAAAAAGCAGTAGAACGTGCGTGTATTACTGGTGGTTATGCCACAACTTATG
TAGGAGATTATGAAGGATTTCCTGATAAATCTCGATTAGAACGTTTAACCAATCTATCTACGAGCGAAGATGTGAGTCGT
TAA

Upstream 100 bases:

>100_bases
AAAGATAGAATGCTAAAACAAAAAGAAACAGTTATTACAAACTTAAGAGATACAGCCAAACTTATTTCAAATGGTATGGG
ATATGTTTAAGGAGAGGAGT

Downstream 100 bases:

>100_bases
TTTAATCATTTATAAAAGGAGACTAACTCAATGGATATCTTAAAACAGGTTGAAAAAGAAAAGCTAATTGCTATTATACG
TGGGTACGATACCAAAGAAA

Product: 2-keto-3-deoxygluconate kinase

Products: NA

Alternate protein names: 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MKRMDVIGIGETMVSLTPDKYGLIRQTSSFEPRVAGTETNTLIGLSRLGHNTGFISRLGEDELGAMVLKELRGENVDTKL
IDLDPYHQTGLFLKEIINESDVHVYYYRQHSAASQMTRELLDESYISSASYLFITGITPAISESCKQTIFTAINMAKNNG
VKIVFDPNIRKKLWSESEARQTLIEILKLSDIILPGISEGQFLLDSNDPEEIGKKCVDLGAELVVVKLGENGAYYCTSDH
GDYVPSFPVKQVRDPVGAGDAFAAGLLSGLIDELSIEKAVERACITGGYATTYVGDYEGFPDKSRLERLTNLSTSEDVSR

Sequences:

>Translated_320_residues
MKRMDVIGIGETMVSLTPDKYGLIRQTSSFEPRVAGTETNTLIGLSRLGHNTGFISRLGEDELGAMVLKELRGENVDTKL
IDLDPYHQTGLFLKEIINESDVHVYYYRQHSAASQMTRELLDESYISSASYLFITGITPAISESCKQTIFTAINMAKNNG
VKIVFDPNIRKKLWSESEARQTLIEILKLSDIILPGISEGQFLLDSNDPEEIGKKCVDLGAELVVVKLGENGAYYCTSDH
GDYVPSFPVKQVRDPVGAGDAFAAGLLSGLIDELSIEKAVERACITGGYATTYVGDYEGFPDKSRLERLTNLSTSEDVSR
>Mature_320_residues
MKRMDVIGIGETMVSLTPDKYGLIRQTSSFEPRVAGTETNTLIGLSRLGHNTGFISRLGEDELGAMVLKELRGENVDTKL
IDLDPYHQTGLFLKEIINESDVHVYYYRQHSAASQMTRELLDESYISSASYLFITGITPAISESCKQTIFTAINMAKNNG
VKIVFDPNIRKKLWSESEARQTLIEILKLSDIILPGISEGQFLLDSNDPEEIGKKCVDLGAELVVVKLGENGAYYCTSDH
GDYVPSFPVKQVRDPVGAGDAFAAGLLSGLIDELSIEKAVERACITGGYATTYVGDYEGFPDKSRLERLTNLSTSEDVSR

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI87082281, Length=301, Percent_Identity=26.9102990033223, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI87081971, Length=317, Percent_Identity=25.8675078864353, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790193, Length=243, Percent_Identity=25.1028806584362, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788417, Length=305, Percent_Identity=24.2622950819672, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.45 [H]

Molecular weight: Translated: 35224; Mature: 35224

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRMDVIGIGETMVSLTPDKYGLIRQTSSFEPRVAGTETNTLIGLSRLGHNTGFISRLGE
CCCCEEEECCCHHEEECCCCCCCEECCCCCCCCCCCCCCCCEEEHHHHCCCCHHHHHCCC
DELGAMVLKELRGENVDTKLIDLDPYHQTGLFLKEIINESDVHVYYYRQHSAASQMTREL
HHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHH
LDESYISSASYLFITGITPAISESCKQTIFTAINMAKNNGVKIVFDPNIRKKLWSESEAR
HHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCHHHHH
QTLIEILKLSDIILPGISEGQFLLDSNDPEEIGKKCVDLGAELVVVKLGENGAYYCTSDH
HHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHCCCEEEEEEECCCCCEEEECCC
GDYVPSFPVKQVRDPVGAGDAFAAGLLSGLIDELSIEKAVERACITGGYATTYVGDYEGF
CCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCC
PDKSRLERLTNLSTSEDVSR
CCHHHHHHHHCCCCHHHCCC
>Mature Secondary Structure
MKRMDVIGIGETMVSLTPDKYGLIRQTSSFEPRVAGTETNTLIGLSRLGHNTGFISRLGE
CCCCEEEECCCHHEEECCCCCCCEECCCCCCCCCCCCCCCCEEEHHHHCCCCHHHHHCCC
DELGAMVLKELRGENVDTKLIDLDPYHQTGLFLKEIINESDVHVYYYRQHSAASQMTREL
HHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHH
LDESYISSASYLFITGITPAISESCKQTIFTAINMAKNNGVKIVFDPNIRKKLWSESEAR
HHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCHHHHH
QTLIEILKLSDIILPGISEGQFLLDSNDPEEIGKKCVDLGAELVVVKLGENGAYYCTSDH
HHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHCCCEEEEEEECCCCCEEEECCC
GDYVPSFPVKQVRDPVGAGDAFAAGLLSGLIDELSIEKAVERACITGGYATTYVGDYEGF
CCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCC
PDKSRLERLTNLSTSEDVSR
CCHHHHHHHHCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]