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The map label for this gene is mrpF [H]

Identifier: 23099451

GI number: 23099451

Start: 2021640

End: 2021918

Strand: Direct

Name: mrpF [H]

Synonym: OB1996

Alternate gene names: 23099451

Gene position: 2021640-2021918 (Clockwise)

Preceding gene: 23099450

Following gene: 23099452

Centisome position: 55.68

GC content: 36.56

Gene sequence:

>279_bases
ATGATGAATACGATTCTTACGATTGCATTAGTAATCATGGCAATAACGCTTGCTTTGTTATTTATACGTGTAATCATTGG
TCCTTCCATTCCTGATCGAATTTTAGCTTTAGATGCGATTGGCGTAACGCTTGTAGGTTTTATTGGTATTATCATGATAA
AACAAGATACAATCGTTTATTCGGATGTTGTACTTCTGTTAAGCATACTAGCTTTTGTTGGTACCTTCGCCCTATCAAAA
TTCTTAGAAAGGGGTGCTGTTATTGAGCCAGGGGATTGA

Upstream 100 bases:

>100_bases
AGACTATCTATGTACACGCCATTGATGTTCCAGATCGAGAAGAAGTGATTCGTGATGTACAGAATACATTCGAACGAGCG
ATTATGGAGGTGACAAAGTA

Downstream 100 bases:

>100_bases
TACAGTCGTAGTGTTATTGGTAATAATTGGTTTATTCTTTACGGTTGTCTCCGCTATTGGAGTATTGCGTCTACCTGATG
TATATTCCCGTACACATGCA

Product: putative monovalent cation/H+ antiporter subunit F

Products: NA

Alternate protein names: Mrp complex subunit F; Multiple resistance and pH homeostasis protein F [H]

Number of amino acids: Translated: 92; Mature: 92

Protein sequence:

>92_residues
MMNTILTIALVIMAITLALLFIRVIIGPSIPDRILALDAIGVTLVGFIGIIMIKQDTIVYSDVVLLLSILAFVGTFALSK
FLERGAVIEPGD

Sequences:

>Translated_92_residues
MMNTILTIALVIMAITLALLFIRVIIGPSIPDRILALDAIGVTLVGFIGIIMIKQDTIVYSDVVLLLSILAFVGTFALSK
FLERGAVIEPGD
>Mature_92_residues
MMNTILTIALVIMAITLALLFIRVIIGPSIPDRILALDAIGVTLVGFIGIIMIKQDTIVYSDVVLLLSILAFVGTFALSK
FLERGAVIEPGD

Specific function: Mnh complex is a Na(+)Li(+)/H(+) antiporter involved in Na(+) and/or Li(+) excretion and Na(+) resistance. Na(+)/H(+) antiport consumes a transmembrane electrical potential, and is thus inferred to be electrogenic. Does not transport K(+), Ca(2+) or Mg(2+

COG id: COG2212

COG function: function code P; Multisubunit Na+/H+ antiporter, MnhF subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007208 [H]

Pfam domain/function: PF04066 MrpF_PhaF [H]

EC number: NA

Molecular weight: Translated: 9857; Mature: 9857

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNTILTIALVIMAITLALLFIRVIIGPSIPDRILALDAIGVTLVGFIGIIMIKQDTIVY
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
SDVVLLLSILAFVGTFALSKFLERGAVIEPGD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MMNTILTIALVIMAITLALLFIRVIIGPSIPDRILALDAIGVTLVGFIGIIMIKQDTIVY
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
SDVVLLLSILAFVGTFALSKFLERGAVIEPGD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11356194 [H]