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The map label for this gene is nadD

Identifier: 23099440

GI number: 23099440

Start: 2012274

End: 2012849

Strand: Reverse

Name: nadD

Synonym: OB1985

Alternate gene names: 23099440

Gene position: 2012849-2012274 (Counterclockwise)

Preceding gene: 23099441

Following gene: 23099439

Centisome position: 55.44

GC content: 37.15

Gene sequence:

>576_bases
TTGAGGGAAATAGGTATCCTTGGTGGCACTTTTGACCCTCCGCATCTGGGTCATTTATTGATAGCGGAAGAAGTTAGAAG
AGCTAAAGAATTAGATGAGATCTGGTTTATTCCTACGAATACACCTCCTCATAAGGAGGACACGACTACAAGTGCAGACC
ATCGGACATCGATGATACAATTAGCAATTGATAGTCATCCGTCTTTTAAGTTAAATGATATGGAATTAAAAAGGGAAGGG
AAATCATATACGTATGATACGATCCAGGAATTAACAGACTTGTATCCTTCTCATACTTTCTATTTTATTATTGGCGGAGA
TATGGTGGAGTTTTTACCTAAATGGCATCGGATAGATGAATTATTGGAAATGATAACATTTATTGGTGTGAGCCGTCCGG
GCTATTCATTGCAAACATCTTATCCTGTTGATTTTGTAGATATTCCTACTATCCAATTATCCTCTACAATTTTACGTGAA
AGATTACAAAATAGGGAGTGGATTCGATATCTACTACCCGATTCTGTTATGCAATATGTGAGGGAGCATCAGTTATATGG
ATTTGGACGTAATTAA

Upstream 100 bases:

>100_bases
GCTTGTACAAGTAATTGGGAATAATATCGTATTATATAAAGAGTCAGTTGAAAATAAACAGATTAGGTTACCATAACAGA
ATTACAGAAGGTGATTAATA

Downstream 100 bases:

>100_bases
ACAAGATGTGCAAGCTCAGTTAACAGAGCATAGATTTGCACATACTCTAAGAGTCGTGGATACTGCTGTTGAGTTATCCA
AACGATTTAATGAGTCTATT

Product: nicotinate-nucleotide adenylyltransferase

Products: NA

Alternate protein names: Deamido-NAD(+) diphosphorylase; Deamido-NAD(+) pyrophosphorylase; Nicotinate mononucleotide adenylyltransferase; NaMN adenylyltransferase

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MREIGILGGTFDPPHLGHLLIAEEVRRAKELDEIWFIPTNTPPHKEDTTTSADHRTSMIQLAIDSHPSFKLNDMELKREG
KSYTYDTIQELTDLYPSHTFYFIIGGDMVEFLPKWHRIDELLEMITFIGVSRPGYSLQTSYPVDFVDIPTIQLSSTILRE
RLQNREWIRYLLPDSVMQYVREHQLYGFGRN

Sequences:

>Translated_191_residues
MREIGILGGTFDPPHLGHLLIAEEVRRAKELDEIWFIPTNTPPHKEDTTTSADHRTSMIQLAIDSHPSFKLNDMELKREG
KSYTYDTIQELTDLYPSHTFYFIIGGDMVEFLPKWHRIDELLEMITFIGVSRPGYSLQTSYPVDFVDIPTIQLSSTILRE
RLQNREWIRYLLPDSVMQYVREHQLYGFGRN
>Mature_191_residues
MREIGILGGTFDPPHLGHLLIAEEVRRAKELDEIWFIPTNTPPHKEDTTTSADHRTSMIQLAIDSHPSFKLNDMELKREG
KSYTYDTIQELTDLYPSHTFYFIIGGDMVEFLPKWHRIDELLEMITFIGVSRPGYSLQTSYPVDFVDIPTIQLSSTILRE
RLQNREWIRYLLPDSVMQYVREHQLYGFGRN

Specific function: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)

COG id: COG1057

COG function: function code H; Nicotinic acid mononucleotide adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadD family

Homologues:

Organism=Escherichia coli, GI1786858, Length=207, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADD_OCEIH (Q8EPV1)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_692906.1
- ProteinModelPortal:   Q8EPV1
- SMR:   Q8EPV1
- GeneID:   1018462
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1985
- NMPDR:   fig|221109.1.peg.1985
- HOGENOM:   HBG739448
- OMA:   HLLMANE
- BioCyc:   OIHE221109:OB1985-MONOMER
- BRENDA:   2.7.7.18
- HAMAP:   MF_00244
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR005248
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR12039
- TIGRFAMs:   TIGR00125
- TIGRFAMs:   TIGR00482

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.18

Molecular weight: Translated: 22360; Mature: 22360

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREIGILGGTFDPPHLGHLLIAEEVRRAKELDEIWFIPTNTPPHKEDTTTSADHRTSMIQ
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCHHHHEEEE
LAIDSHPSFKLNDMELKREGKSYTYDTIQELTDLYPSHTFYFIIGGDMVEFLPKWHRIDE
EEECCCCCEEECHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHH
LLEMITFIGVSRPGYSLQTSYPVDFVDIPTIQLSSTILRERLQNREWIRYLLPDSVMQYV
HHHHHHHHCCCCCCCCEECCCCCCEEECCCHHHHHHHHHHHHCCHHHHHHHCCHHHHHHH
REHQLYGFGRN
HHHHCCCCCCC
>Mature Secondary Structure
MREIGILGGTFDPPHLGHLLIAEEVRRAKELDEIWFIPTNTPPHKEDTTTSADHRTSMIQ
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCHHHHEEEE
LAIDSHPSFKLNDMELKREGKSYTYDTIQELTDLYPSHTFYFIIGGDMVEFLPKWHRIDE
EEECCCCCEEECHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHH
LLEMITFIGVSRPGYSLQTSYPVDFVDIPTIQLSSTILRERLQNREWIRYLLPDSVMQYV
HHHHHHHHCCCCCCCCEECCCCCCEEECCCHHHHHHHHHHHHCCHHHHHHHCCHHHHHHH
REHQLYGFGRN
HHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376