Click here to switch to the map view.

The map label for this gene is glcK [H]

Identifier: 23099374

GI number: 23099374

Start: 1946831

End: 1947808

Strand: Reverse

Name: glcK [H]

Synonym: OB1919

Alternate gene names: 23099374

Gene position: 1947808-1946831 (Counterclockwise)

Preceding gene: 23099375

Following gene: 23099373

Centisome position: 53.65

GC content: 37.12

Gene sequence:

>978_bases
GTGGACAAACATTTATTAGTGGGTGTTGATATTGGGGGTACTACAGTTAAAATAGGCTTTATATCGGAAAAAGGGAAGGT
ACTAGACAAGTGGGAAATATCTACAAATCTACTTGATGGTGGAAAATATATTGTACCCGAAATCTGGTCTTCTGTGGAGT
CTAAAATAAAGCAGCTAAGTTATTCTTTGTCTTCGATAGTTGGAATTGGTGTAGGAGCGCCAGGATTTATTGATGCAGAA
AAGGGATTTGTTCATGAAGCTGTTAATATTGGTTGGAAAAATTTTGCTTTAGCTGAAGCTTTTAAAGCTTATGTGAGTAT
CCCTGTATACGTTGAAAATGATGCCAATACTGCTGTGCTTGGAGAAAATTGGGTTGGTGCAGGGAATCAAGCAGACAATT
TAATTGCGATTACACTTGGAACCGGTGTTGGTGGAGGAATCATCGCCAATGGTCGAATTTTAAATGGAGCTAATGGAATG
GCAGGAGAATTAGGACATATGATTGTGGAAGAGGATGGCGCACGTTGTAATTGTGGTAATCAAGGTTGTTTAGAAACGAT
AACTTCTGCTACGGGTATTGTGAGACAAGCATTAGAAAAAGTAATTGAAATACCTAATTCAACATTAGCAGAAGTATATA
ATAAAAATGGTGAAATTACTTCAAAAGAGATTTTTGACCTTGCAAAGGAAGGCGATGTCGCAGCAAAATCGATTGTTGAT
CATACTGCTGATGTCTTAGGGAAAGTCTTAGCAAACATGGGTGTGATTATAAATCCATCTAAAGTGTTAATTGGCGGTGG
AGTTTCTAAAGCTGGAGATCAGTTAATTGATGCTATCCAATTTGCTTTTGAAAAACATGCATTACCAAGAGTTGCAGAGG
CTTGTTCAATTAAAACTGCTCAATTAGGAAATGATGCAGGCATTATTGGAGCAGCTTACTTGGTATATTCTTCAAAAAAT
AGCACATTTTTCACTTGA

Upstream 100 bases:

>100_bases
TAAATGATTTGTATCAATATGGATTTATTACTCAACATGAATTTCTCATGGCAAAACTTTGCGTTGAAAAAGAAAAAAAT
CAATTAAAGGGGAATGGATA

Downstream 100 bases:

>100_bases
TTTTTTTTGATTTTCTACTAAAATAGTAAGTTATGAGTACAGTGTAAAAAATCTTAAAAAAGTGAAACTTTAATGGCATG
ATATTCGTCTATATTAATAA

Product: glucose kinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MDKHLLVGVDIGGTTVKIGFISEKGKVLDKWEISTNLLDGGKYIVPEIWSSVESKIKQLSYSLSSIVGIGVGAPGFIDAE
KGFVHEAVNIGWKNFALAEAFKAYVSIPVYVENDANTAVLGENWVGAGNQADNLIAITLGTGVGGGIIANGRILNGANGM
AGELGHMIVEEDGARCNCGNQGCLETITSATGIVRQALEKVIEIPNSTLAEVYNKNGEITSKEIFDLAKEGDVAAKSIVD
HTADVLGKVLANMGVIINPSKVLIGGGVSKAGDQLIDAIQFAFEKHALPRVAEACSIKTAQLGNDAGIIGAAYLVYSSKN
STFFT

Sequences:

>Translated_325_residues
MDKHLLVGVDIGGTTVKIGFISEKGKVLDKWEISTNLLDGGKYIVPEIWSSVESKIKQLSYSLSSIVGIGVGAPGFIDAE
KGFVHEAVNIGWKNFALAEAFKAYVSIPVYVENDANTAVLGENWVGAGNQADNLIAITLGTGVGGGIIANGRILNGANGM
AGELGHMIVEEDGARCNCGNQGCLETITSATGIVRQALEKVIEIPNSTLAEVYNKNGEITSKEIFDLAKEGDVAAKSIVD
HTADVLGKVLANMGVIINPSKVLIGGGVSKAGDQLIDAIQFAFEKHALPRVAEACSIKTAQLGNDAGIIGAAYLVYSSKN
STFFT
>Mature_325_residues
MDKHLLVGVDIGGTTVKIGFISEKGKVLDKWEISTNLLDGGKYIVPEIWSSVESKIKQLSYSLSSIVGIGVGAPGFIDAE
KGFVHEAVNIGWKNFALAEAFKAYVSIPVYVENDANTAVLGENWVGAGNQADNLIAITLGTGVGGGIIANGRILNGANGM
AGELGHMIVEEDGARCNCGNQGCLETITSATGIVRQALEKVIEIPNSTLAEVYNKNGEITSKEIFDLAKEGDVAAKSIVD
HTADVLGKVLANMGVIINPSKVLIGGGVSKAGDQLIDAIQFAFEKHALPRVAEACSIKTAQLGNDAGIIGAAYLVYSSKN
STFFT

Specific function: May Be A Regulator In Specific Sugar Metabolism. May Influence The Rate Of Glucose Uptake Or Glycolysis In Cells In The Rich Medium. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=265, Percent_Identity=27.9245283018868, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI298566315, Length=265, Percent_Identity=27.9245283018868, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI4885285, Length=265, Percent_Identity=27.9245283018868, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI190014632, Length=265, Percent_Identity=27.9245283018868, Blast_Score=101, Evalue=9e-22,
Organism=Escherichia coli, GI1787878, Length=282, Percent_Identity=29.7872340425532, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1786891, Length=297, Percent_Identity=29.6296296296296, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI1787363, Length=327, Percent_Identity=29.9694189602446, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI87081733, Length=327, Percent_Identity=28.1345565749235, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI87082127, Length=213, Percent_Identity=28.169014084507, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082230, Length=269, Percent_Identity=26.7657992565056, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1790522, Length=270, Percent_Identity=25.5555555555556, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 33983; Mature: 33983

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKHLLVGVDIGGTTVKIGFISEKGKVLDKWEISTNLLDGGKYIVPEIWSSVESKIKQLS
CCCEEEEEEECCCCEEEEEEECCCCCEEEEEECCCEEECCCCEEHHHHHHHHHHHHHHHH
YSLSSIVGIGVGAPGFIDAEKGFVHEAVNIGWKNFALAEAFKAYVSIPVYVENDANTAVL
HHHHHHHCCCCCCCCCEECCCCHHHHHHHCCCHHHHHHHHHHHHEEEEEEEECCCCEEEE
GENWVGAGNQADNLIAITLGTGVGGGIIANGRILNGANGMAGELGHMIVEEDGARCNCGN
CCCCCCCCCCCCCEEEEEECCCCCCCEEECCEEEECCCCCCHHHCCEEEECCCCCCCCCC
QGCLETITSATGIVRQALEKVIEIPNSTLAEVYNKNGEITSKEIFDLAKEGDVAAKSIVD
CHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHH
HTADVLGKVLANMGVIINPSKVLIGGGVSKAGDQLIDAIQFAFEKHALPRVAEACSIKTA
HHHHHHHHHHHHCCEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHH
QLGNDAGIIGAAYLVYSSKNSTFFT
HCCCCCCCEEEEEEEEECCCCCCCC
>Mature Secondary Structure
MDKHLLVGVDIGGTTVKIGFISEKGKVLDKWEISTNLLDGGKYIVPEIWSSVESKIKQLS
CCCEEEEEEECCCCEEEEEEECCCCCEEEEEECCCEEECCCCEEHHHHHHHHHHHHHHHH
YSLSSIVGIGVGAPGFIDAEKGFVHEAVNIGWKNFALAEAFKAYVSIPVYVENDANTAVL
HHHHHHHCCCCCCCCCEECCCCHHHHHHHCCCHHHHHHHHHHHHEEEEEEEECCCCEEEE
GENWVGAGNQADNLIAITLGTGVGGGIIANGRILNGANGMAGELGHMIVEEDGARCNCGN
CCCCCCCCCCCCCEEEEEECCCCCCCEEECCEEEECCCCCCHHHCCEEEECCCCCCCCCC
QGCLETITSATGIVRQALEKVIEIPNSTLAEVYNKNGEITSKEIFDLAKEGDVAAKSIVD
CHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHH
HTADVLGKVLANMGVIINPSKVLIGGGVSKAGDQLIDAIQFAFEKHALPRVAEACSIKTA
HHHHHHHHHHHHCCEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHH
QLGNDAGIIGAAYLVYSSKNSTFFT
HCCCCCCCEEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]