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The map label for this gene is yqkF [H]

Identifier: 23099307

GI number: 23099307

Start: 1882540

End: 1883460

Strand: Direct

Name: yqkF [H]

Synonym: OB1852

Alternate gene names: 23099307

Gene position: 1882540-1883460 (Clockwise)

Preceding gene: 23099298

Following gene: 23099310

Centisome position: 51.85

GC content: 33.33

Gene sequence:

>921_bases
ATGCGTCATAATTTACTAGGTAAATCTAACATAAGTATATCTGAATTAACATTAGGATGCATGTCGCTTGGATCTGACTA
TCAACATGCAAGTGAAATAATTGATACTGCTATAGAGAATGGAATTAATCACCTAGACACAGCCGATTTATATGATTTTG
GTTTAAATGAACAGATTGTTGGAAAAGCAATAAAACATCGCCGGGATCAAGTAGTCATTACTTCAAAAGTAGGGAATCAT
TTCCAAGCAGATTCAAAGGAATGGTATTGGGATCCTTCGAAAAAATATATTCATCAAGCTGTTCGGAACAGCTTGAGTCG
ACTGCAATTAGATTATTTGGATGTATGTATGCTACACGGTGGAACCATTGACGATCCAATTGATGAGACCATTGAAGCAT
TTGAAGAACTAAAAAAAGATGGTTTGATACGCACGTATGGTATTTCATCTATCAGAACAAATGTTATAAGAGAATATGCT
AAACGTTCCTCTATTGATGTTTTAATGACTCAATATAGTCTATTAGATCGTAGACCAGAGGAAGAAATACTACCTTTATC
ACTAGAAAATAACATTAGTGTAGTATGTAGAGGGCCTCTTGCAAAAGGATTGGTAAGCAATCAAATGAAAGATATCATTG
AGAAAAAAGGAGAAAACGGGTATTTAAATTATAGTTATGAGGAATTAGTAAAATTGAATGAAAGACTAAATGAAATTCGT
TCCGATTATTCTATACAAGAATTAGCTATGCATTACGTTGGAGATCACCCAGCTGTTACTTCAACCGTTTTTGGAGCTAG
TTCATTAAATCAATTAGAAGAAAATATTCGTGAATATGATAAAACAGACCATATAGATGAAACTCTTTATCGTCAGTTAC
AAGAGCTTACAAAAGAAGCAACTTACGATAATCATCGATGA

Upstream 100 bases:

>100_bases
TGATTTTCTTCCTTTCTTAATTCCTATGTGTGTATAAGTTGTATTCTTTTATTACTAATTCTACAATAATCATATAATCC
ATATGATAAGGAGGCAAATA

Downstream 100 bases:

>100_bases
ATATATAAATTCAAGAGGCAAGAAAGTGTGATATTGGGACAAAAGCATTATCTTAAAAAATATAAATCGAATTGATGGCT
TTTGAAAACCCGCTGCAGAA

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MRHNLLGKSNISISELTLGCMSLGSDYQHASEIIDTAIENGINHLDTADLYDFGLNEQIVGKAIKHRRDQVVITSKVGNH
FQADSKEWYWDPSKKYIHQAVRNSLSRLQLDYLDVCMLHGGTIDDPIDETIEAFEELKKDGLIRTYGISSIRTNVIREYA
KRSSIDVLMTQYSLLDRRPEEEILPLSLENNISVVCRGPLAKGLVSNQMKDIIEKKGENGYLNYSYEELVKLNERLNEIR
SDYSIQELAMHYVGDHPAVTSTVFGASSLNQLEENIREYDKTDHIDETLYRQLQELTKEATYDNHR

Sequences:

>Translated_306_residues
MRHNLLGKSNISISELTLGCMSLGSDYQHASEIIDTAIENGINHLDTADLYDFGLNEQIVGKAIKHRRDQVVITSKVGNH
FQADSKEWYWDPSKKYIHQAVRNSLSRLQLDYLDVCMLHGGTIDDPIDETIEAFEELKKDGLIRTYGISSIRTNVIREYA
KRSSIDVLMTQYSLLDRRPEEEILPLSLENNISVVCRGPLAKGLVSNQMKDIIEKKGENGYLNYSYEELVKLNERLNEIR
SDYSIQELAMHYVGDHPAVTSTVFGASSLNQLEENIREYDKTDHIDETLYRQLQELTKEATYDNHR
>Mature_306_residues
MRHNLLGKSNISISELTLGCMSLGSDYQHASEIIDTAIENGINHLDTADLYDFGLNEQIVGKAIKHRRDQVVITSKVGNH
FQADSKEWYWDPSKKYIHQAVRNSLSRLQLDYLDVCMLHGGTIDDPIDETIEAFEELKKDGLIRTYGISSIRTNVIREYA
KRSSIDVLMTQYSLLDRRPEEEILPLSLENNISVVCRGPLAKGLVSNQMKDIIEKKGENGYLNYSYEELVKLNERLNEIR
SDYSIQELAMHYVGDHPAVTSTVFGASSLNQLEENIREYDKTDHIDETLYRQLQELTKEATYDNHR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI4504825, Length=297, Percent_Identity=28.2828282828283, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI27436969, Length=297, Percent_Identity=28.2828282828283, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI27436966, Length=301, Percent_Identity=27.2425249169435, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI27436964, Length=301, Percent_Identity=26.9102990033223, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI27436962, Length=301, Percent_Identity=26.9102990033223, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI27436971, Length=301, Percent_Identity=26.2458471760797, Blast_Score=85, Evalue=8e-17,
Organism=Escherichia coli, GI1788070, Length=322, Percent_Identity=30.4347826086957, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI87081735, Length=310, Percent_Identity=29.6774193548387, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1789199, Length=319, Percent_Identity=26.6457680250784, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1789375, Length=306, Percent_Identity=27.1241830065359, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788081, Length=202, Percent_Identity=28.7128712871287, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787674, Length=233, Percent_Identity=24.8927038626609, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87082198, Length=176, Percent_Identity=27.8409090909091, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786400, Length=146, Percent_Identity=32.8767123287671, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI212645785, Length=291, Percent_Identity=27.1477663230241, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323998, Length=304, Percent_Identity=25, Blast_Score=82, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6325169, Length=297, Percent_Identity=26.9360269360269, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319958, Length=276, Percent_Identity=24.2753623188406, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319951, Length=303, Percent_Identity=24.4224422442244, Blast_Score=69, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24646155, Length=220, Percent_Identity=30.9090909090909, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24646159, Length=293, Percent_Identity=26.962457337884, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24640980, Length=343, Percent_Identity=24.198250728863, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI45549126, Length=343, Percent_Identity=24.198250728863, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35088; Mature: 35088

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHNLLGKSNISISELTLGCMSLGSDYQHASEIIDTAIENGINHLDTADLYDFGLNEQIV
CCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHH
GKAIKHRRDQVVITSKVGNHFQADSKEWYWDPSKKYIHQAVRNSLSRLQLDYLDVCMLHG
HHHHHCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GTIDDPIDETIEAFEELKKDGLIRTYGISSIRTNVIREYAKRSSIDVLMTQYSLLDRRPE
CCCCCHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
EEILPLSLENNISVVCRGPLAKGLVSNQMKDIIEKKGENGYLNYSYEELVKLNERLNEIR
CCCCCEEECCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
SDYSIQELAMHYVGDHPAVTSTVFGASSLNQLEENIREYDKTDHIDETLYRQLQELTKEA
HCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
TYDNHR
CCCCCC
>Mature Secondary Structure
MRHNLLGKSNISISELTLGCMSLGSDYQHASEIIDTAIENGINHLDTADLYDFGLNEQIV
CCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHH
GKAIKHRRDQVVITSKVGNHFQADSKEWYWDPSKKYIHQAVRNSLSRLQLDYLDVCMLHG
HHHHHCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GTIDDPIDETIEAFEELKKDGLIRTYGISSIRTNVIREYAKRSSIDVLMTQYSLLDRRPE
CCCCCHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
EEILPLSLENNISVVCRGPLAKGLVSNQMKDIIEKKGENGYLNYSYEELVKLNERLNEIR
CCCCCEEECCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
SDYSIQELAMHYVGDHPAVTSTVFGASSLNQLEENIREYDKTDHIDETLYRQLQELTKEA
HCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
TYDNHR
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]