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The map label for this gene is mecA

Identifier: 23099266

GI number: 23099266

Start: 1848145

End: 1848723

Strand: Reverse

Name: mecA

Synonym: OB1811

Alternate gene names: 23099266

Gene position: 1848723-1848145 (Counterclockwise)

Preceding gene: 23099267

Following gene: 23099265

Centisome position: 50.92

GC content: 31.78

Gene sequence:

>579_bases
ATGCGAATAGAGCGTGTTTCTACAGATCAATTTAAAATTTTTTTAACGTTTGATGATCTTATTGAGCGTGGTTTTACAAG
AGAAGATTTATGGCATGATGCATCAAATGTTCGAAGCTTATTCAGTGATATGATGTATGAAGCAAGTAGTGAACTAGGTA
TTGAATTAGAAGGAATGTTATTAGTCCAAGTTCATTTAATGCAAGCTCAAGGAATGCATATATTTGTAACACAACAATAC
GAGGATAATAGTGAGGATGAAGATTACATCGAGATGAAGGTTACTTTGGATGAGAGTAAAGAACTAATTTTTTCCTTTAT
GGACTTTGAAGATATAATCTCTGTTACATCTTATTTAGATCCAATGGGATTGGAAAACATACGACTTTATTATATGGAAG
ATAGATATTATATGATTTTAGATCATATTGAGTTATCGAGAGTCGATAAAGAGGATATAATTGGAGTTATGTCTGAATAC
GCTAATCCTAGTATTGTCACTTCTCATCGAATTGAAGAATATGGGAAACTGATTATGGAAGAGAATACAGTTCAGCAAAT
CAAGCGATTCTTTTACTAA

Upstream 100 bases:

>100_bases
TAGGATAAAATGCATATAGTATATAAAGTGCTTCTAAACATCACTATAAATTGTGCAGTGTAATGTAGAATGAGCACTTC
GATAAGGGGGAGGATGCAGG

Downstream 100 bases:

>100_bases
GTTGATGGTGTTTATAACATTGATTATTAAATAAACGAGATTATTTTGAATAATTCCATTATAAGAACATCTGATAATAG
GCGTAAGATTTGATTTATGT

Product: adaptor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MRIERVSTDQFKIFLTFDDLIERGFTREDLWHDASNVRSLFSDMMYEASSELGIELEGMLLVQVHLMQAQGMHIFVTQQY
EDNSEDEDYIEMKVTLDESKELIFSFMDFEDIISVTSYLDPMGLENIRLYYMEDRYYMILDHIELSRVDKEDIIGVMSEY
ANPSIVTSHRIEEYGKLIMEENTVQQIKRFFY

Sequences:

>Translated_192_residues
MRIERVSTDQFKIFLTFDDLIERGFTREDLWHDASNVRSLFSDMMYEASSELGIELEGMLLVQVHLMQAQGMHIFVTQQY
EDNSEDEDYIEMKVTLDESKELIFSFMDFEDIISVTSYLDPMGLENIRLYYMEDRYYMILDHIELSRVDKEDIIGVMSEY
ANPSIVTSHRIEEYGKLIMEENTVQQIKRFFY
>Mature_192_residues
MRIERVSTDQFKIFLTFDDLIERGFTREDLWHDASNVRSLFSDMMYEASSELGIELEGMLLVQVHLMQAQGMHIFVTQQY
EDNSEDEDYIEMKVTLDESKELIFSFMDFEDIISVTSYLDPMGLENIRLYYMEDRYYMILDHIELSRVDKEDIIGVMSEY
ANPSIVTSHRIEEYGKLIMEENTVQQIKRFFY

Specific function: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When ove

COG id: COG4862

COG function: function code OTN; Negative regulator of genetic competence, sporulation and motility

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mecA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MECA_OCEIH (Q8EQ97)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_692732.1
- GeneID:   1018305
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1811
- NMPDR:   fig|221109.1.peg.1812
- HOGENOM:   HBG491202
- OMA:   DYIEMQV
- ProtClustDB:   PRK02899
- BioCyc:   OIHE221109:OB1811-MONOMER
- HAMAP:   MF_01124
- InterPro:   IPR008681
- PIRSF:   PIRSF029008

Pfam domain/function: PF05389 MecA

EC number: NA

Molecular weight: Translated: 22906; Mature: 22906

Theoretical pI: Translated: 4.07; Mature: 4.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.8 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.8 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIERVSTDQFKIFLTFDDLIERGFTREDLWHDASNVRSLFSDMMYEASSELGIELEGML
CCCCCCCCCCEEEEEEHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCCEEECCEE
LVQVHLMQAQGMHIFVTQQYEDNSEDEDYIEMKVTLDESKELIFSFMDFEDIISVTSYLD
EEEEEEHHHCCCEEEEEECCCCCCCCCCEEEEEEEECCHHHHHHHHHCHHHHHHHHHHCC
PMGLENIRLYYMEDRYYMILDHIELSRVDKEDIIGVMSEYANPSIVTSHRIEEYGKLIME
CCCCCCEEEEEEECCEEEEEECHHHHHCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHC
ENTVQQIKRFFY
CHHHHHHHHHCC
>Mature Secondary Structure
MRIERVSTDQFKIFLTFDDLIERGFTREDLWHDASNVRSLFSDMMYEASSELGIELEGML
CCCCCCCCCCEEEEEEHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCCEEECCEE
LVQVHLMQAQGMHIFVTQQYEDNSEDEDYIEMKVTLDESKELIFSFMDFEDIISVTSYLD
EEEEEEHHHCCCEEEEEECCCCCCCCCCEEEEEEEECCHHHHHHHHHCHHHHHHHHHHCC
PMGLENIRLYYMEDRYYMILDHIELSRVDKEDIIGVMSEYANPSIVTSHRIEEYGKLIME
CCCCCCEEEEEEECCEEEEEECHHHHHCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHC
ENTVQQIKRFFY
CHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376