Click here to switch to the map view.

The map label for this gene is cmk

Identifier: 23099257

GI number: 23099257

Start: 1837348

End: 1838040

Strand: Reverse

Name: cmk

Synonym: OB1802

Alternate gene names: 23099257

Gene position: 1838040-1837348 (Counterclockwise)

Preceding gene: 23099258

Following gene: 23099256

Centisome position: 50.63

GC content: 34.78

Gene sequence:

>693_bases
ATGGAACAAAGAATCACAGTAGCAATTGACGGACCAGCAGCAGCAGGTAAAAGTACTGTAGCTAAAATGATCGCAAATCA
ATTAGGATTTATTTATGTGGACACGGGTGCAATGTATCGTGCTTTAACTTATCAGGCTTTACAAGAAGGTATAGACCCAA
AAAATGAAGATAGCGTTCTAACTATATTAATGAATTCCAATATAGAATTACGTCAGGCTGAAAATGGACAACGAGTCTTT
GTAAACAACAAAGATGTCTCCGAAGAAATTCGTTATCCAGACGTAACATCAAAAGTATCTTTTGTAGCAGAACATCCTTC
TATACGTAAAGAGATGGTATCTCGACAGCAAAAACTTGCAAATAACCGCAGTGTGGTAATGGATGGAAGAGATATTGGTA
CGCATGTATTACCAGATGCGGAGGTAAAAATCTTTTTAATTGCCTCAGTGGAAGAAAGAGCAAAAAGACGTCATGAAGAG
AATATTAAAAAGGGTATACCTTCAGATATAAAGTTATTAAAAAAAGAAATTAGTGATCGAGATGAAATCGATTCGAATCG
AGAGGTATCTCCATTAATCAAAGCAGAAGACGCAATAGAAGTTGATACTACATCACTTTCAATTGCAGAAGTAAAAGATC
AAATCTTAAATGAAATCTTTAAATACAATACCCAAAATAATAAGGGTGTATAG

Upstream 100 bases:

>100_bases
AGAAATTAATTCGACCATAAAAAATAGAATATGTTATGATTATCATGTAGAAAGATAGCTTGGTAATAGCCAAGTTTTTT
ATTGTAGGAGATGAACATGA

Downstream 100 bases:

>100_bases
AGGGGGAGAAAGGATGCTTTATAAATTTGCTAGATTTGTTATAGCAATCATTTTTTACCCGCTATATCGTATCAAAGTGA
TTGGCAAAGAGAACATACCT

Product: cytidylate kinase

Products: NA

Alternate protein names: CK; Cytidine monophosphate kinase; CMP kinase

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MEQRITVAIDGPAAAGKSTVAKMIANQLGFIYVDTGAMYRALTYQALQEGIDPKNEDSVLTILMNSNIELRQAENGQRVF
VNNKDVSEEIRYPDVTSKVSFVAEHPSIRKEMVSRQQKLANNRSVVMDGRDIGTHVLPDAEVKIFLIASVEERAKRRHEE
NIKKGIPSDIKLLKKEISDRDEIDSNREVSPLIKAEDAIEVDTTSLSIAEVKDQILNEIFKYNTQNNKGV

Sequences:

>Translated_230_residues
MEQRITVAIDGPAAAGKSTVAKMIANQLGFIYVDTGAMYRALTYQALQEGIDPKNEDSVLTILMNSNIELRQAENGQRVF
VNNKDVSEEIRYPDVTSKVSFVAEHPSIRKEMVSRQQKLANNRSVVMDGRDIGTHVLPDAEVKIFLIASVEERAKRRHEE
NIKKGIPSDIKLLKKEISDRDEIDSNREVSPLIKAEDAIEVDTTSLSIAEVKDQILNEIFKYNTQNNKGV
>Mature_230_residues
MEQRITVAIDGPAAAGKSTVAKMIANQLGFIYVDTGAMYRALTYQALQEGIDPKNEDSVLTILMNSNIELRQAENGQRVF
VNNKDVSEEIRYPDVTSKVSFVAEHPSIRKEMVSRQQKLANNRSVVMDGRDIGTHVLPDAEVKIFLIASVEERAKRRHEE
NIKKGIPSDIKLLKKEISDRDEIDSNREVSPLIKAEDAIEVDTTSLSIAEVKDQILNEIFKYNTQNNKGV

Specific function: ATP, Datp, And GTP Are Equally Effective As Phosphate Donors. CMP And Dcmp Are The Best Phosphate Acceptors. [C]

COG id: COG0283

COG function: function code F; Cytidylate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidylate kinase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1787139, Length=219, Percent_Identity=38.3561643835616, Blast_Score=156, Evalue=9e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KCY_OCEIH (Q8CXF5)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_692723.1
- ProteinModelPortal:   Q8CXF5
- SMR:   Q8CXF5
- GeneID:   1018296
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1802
- NMPDR:   fig|221109.1.peg.1803
- HOGENOM:   HBG354377
- OMA:   DIGTVIC
- BioCyc:   OIHE221109:OB1802-MONOMER
- BRENDA:   2.7.4.14
- GO:   GO:0005737
- HAMAP:   MF_00238
- InterPro:   IPR003136
- InterPro:   IPR011994
- PANTHER:   PTHR21299:SF2
- TIGRFAMs:   TIGR00017

Pfam domain/function: PF02224 Cytidylate_kin

EC number: =2.7.4.14

Molecular weight: Translated: 25799; Mature: 25799

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQRITVAIDGPAAAGKSTVAKMIANQLGFIYVDTGAMYRALTYQALQEGIDPKNEDSVL
CCCEEEEEECCCCCCCHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCEE
TILMNSNIELRQAENGQRVFVNNKDVSEEIRYPDVTSKVSFVAEHPSIRKEMVSRQQKLA
EEEECCCEEEEECCCCCEEEECCCCCHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHH
NNRSVVMDGRDIGTHVLPDAEVKIFLIASVEERAKRRHEENIKKGIPSDIKLLKKEISDR
CCCEEEECCCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCH
DEIDSNREVSPLIKAEDAIEVDTTSLSIAEVKDQILNEIFKYNTQNNKGV
HCCCCCCCCCCHHCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MEQRITVAIDGPAAAGKSTVAKMIANQLGFIYVDTGAMYRALTYQALQEGIDPKNEDSVL
CCCEEEEEECCCCCCCHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCEE
TILMNSNIELRQAENGQRVFVNNKDVSEEIRYPDVTSKVSFVAEHPSIRKEMVSRQQKLA
EEEECCCEEEEECCCCCEEEECCCCCHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHH
NNRSVVMDGRDIGTHVLPDAEVKIFLIASVEERAKRRHEENIKKGIPSDIKLLKKEISDR
CCCEEEECCCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCH
DEIDSNREVSPLIKAEDAIEVDTTSLSIAEVKDQILNEIFKYNTQNNKGV
HCCCCCCCCCCHHCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376