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The map label for this gene is 23099164

Identifier: 23099164

GI number: 23099164

Start: 1755297

End: 1756943

Strand: Direct

Name: 23099164

Synonym: OB1709

Alternate gene names: NA

Gene position: 1755297-1756943 (Clockwise)

Preceding gene: 23099163

Following gene: 23099165

Centisome position: 48.35

GC content: 40.26

Gene sequence:

>1647_bases
ATGGAAGCAAACGTTATTGTTGTTGGGGCAGGGATTGCAGGTCTAGTTGCAACGGTAGAGATAGCGCAATCTGGAAAGAA
AGTGATTCTGATTGATCAGGAGCCAGAATCATCTCTTGGAGGACAAGCCTGGTGGTCATTTGGGGGCTTGTTTTTAGTAG
ATTCTAAAGAACAACGAAGACTTAACATAAAAGATTCTTATGAACTCGCATGGAATGATTGGAAATCTACTGCAGGCTTT
GATCGTAAAGACGATGATTGGGGGAGGAAATGGGCAGAGGCATACGTTCAATTTGCTGCTTCCGAAAAAAGAGAGTGGTT
ACGTAGTTATGGAATACGTTTCTTTCCTGTTGTCGGTTGGGCAGAAAGAGGTGGTAGTCTAGCTTCTGGACATGGAAATT
CAGTACCTCGATTTCATATTGTATGGGGAACAGGTCCAGGTATTGTAACTCCATTCGTAGAACGTATGCAATCTTATGTA
AAACAAGGGTTAGTCACTTACCTACCACGTCATCGTGCGGAGCACCTACTCGTTCAAAATGAAACCGTTTACGGTGTTGA
GGGCTCCATTTTAAAAGGTTCTACAGCAAAGCGAGGAGAGGCTAGTAACAGAATTGTAGTAGATAGCTTTTCATTCAAAG
CAGAAAATGTGGTGGTTACATCTGGAGGAATTGGAGCAAACCATGAACTAATACGAAAAAATTGGCCGGAGCGGCTAGGA
AAGCCACCAAAAAATATGTTGAGCGGAGTTCCTGAGCATGTAGATGGAAAAATGTTAGAAGTAGCGGAACATGCTGGAGC
GAGAATTGTTCATCGTGATCGTATGTGGCATTATACAGAAGGTATTAAGAATTGGAATTCGGTCTGGGAAAACCATGGAA
TTCGTATTTTACCAGGTCCATCGTCGATTTGGTTAGATGCAGAAGGAAATCGATTCCATGCACCAAACTATCCAGGATTT
GATACATTAAGCACGTTAGAAGCCATACAAAATACAGGATACGATTATTCATGGTTTATATTAACACAAAAGATTATTGA
GAAAGAATTTGCCTTGTCTGGCTCAGAGCAAAATCCAGACTTAACCAACAAACGAATAAGTGAAGTTTTAAAAAGAGCAC
AATCGGGTGCTCCAGAACCAGTTCAAAAATTCTTAAATCATGGAGAAGATTTTGTAACGGCTTCTAATCTAGAAGACCTC
GTTGAAAAAATGAATCAACTGACGGAAAGTCCGTTATTAAAAGTAGAGCATGTAACATCTCAAATCGAAGCAAGAGATCT
TCAATTAGCTAATAAATTCACCAAAGATTTACAGTTAGCTGCTATGTACAATTCTCGTAAATTCCTAGGTGATAAATTAA
TCCGTACTGCAAAACCACATCCGATATTAAAAGCTGAAAATGGTCCATTAATTGGTGTAAAACTGCATATACTTAGCCGA
AAAACGCTTGGAGGAATACAGACGGATTTATCTGGAAGAGTATTTAATCAACAAAACGTTCTCATCAAAGGATTATATGC
TGCAGGTGAAGTTGCGGGTTTTGGTGGTGGTGGAATGCATGGTTATAGGGCATTAGAAGGAACGTTTGTTGGCGGGTGCT
TATTTAGTGGAAGAACCGTAGGAAGGTCTATTGCAAGAGGAGAGTGA

Upstream 100 bases:

>100_bases
AATGAGAATATAAAGGTATTAAAGAAACTAGTTAATTAGTCATCTTTACTTGAATGATAAGATATACTAGTTTTATAAAT
ACATAACTAGGGGGAGTGTA

Downstream 100 bases:

>100_bases
ATAAGAAAAATTCATTTACTTCTATTTGAAAAATGTGTACTATCAGAATAAATCGTCTTTATTTTGACTAGGTCTCGTTC
ATAAAAAAATCTTCACGTTA

Product: putative FAD-binding dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 548; Mature: 548

Protein sequence:

>548_residues
MEANVIVVGAGIAGLVATVEIAQSGKKVILIDQEPESSLGGQAWWSFGGLFLVDSKEQRRLNIKDSYELAWNDWKSTAGF
DRKDDDWGRKWAEAYVQFAASEKREWLRSYGIRFFPVVGWAERGGSLASGHGNSVPRFHIVWGTGPGIVTPFVERMQSYV
KQGLVTYLPRHRAEHLLVQNETVYGVEGSILKGSTAKRGEASNRIVVDSFSFKAENVVVTSGGIGANHELIRKNWPERLG
KPPKNMLSGVPEHVDGKMLEVAEHAGARIVHRDRMWHYTEGIKNWNSVWENHGIRILPGPSSIWLDAEGNRFHAPNYPGF
DTLSTLEAIQNTGYDYSWFILTQKIIEKEFALSGSEQNPDLTNKRISEVLKRAQSGAPEPVQKFLNHGEDFVTASNLEDL
VEKMNQLTESPLLKVEHVTSQIEARDLQLANKFTKDLQLAAMYNSRKFLGDKLIRTAKPHPILKAENGPLIGVKLHILSR
KTLGGIQTDLSGRVFNQQNVLIKGLYAAGEVAGFGGGGMHGYRALEGTFVGGCLFSGRTVGRSIARGE

Sequences:

>Translated_548_residues
MEANVIVVGAGIAGLVATVEIAQSGKKVILIDQEPESSLGGQAWWSFGGLFLVDSKEQRRLNIKDSYELAWNDWKSTAGF
DRKDDDWGRKWAEAYVQFAASEKREWLRSYGIRFFPVVGWAERGGSLASGHGNSVPRFHIVWGTGPGIVTPFVERMQSYV
KQGLVTYLPRHRAEHLLVQNETVYGVEGSILKGSTAKRGEASNRIVVDSFSFKAENVVVTSGGIGANHELIRKNWPERLG
KPPKNMLSGVPEHVDGKMLEVAEHAGARIVHRDRMWHYTEGIKNWNSVWENHGIRILPGPSSIWLDAEGNRFHAPNYPGF
DTLSTLEAIQNTGYDYSWFILTQKIIEKEFALSGSEQNPDLTNKRISEVLKRAQSGAPEPVQKFLNHGEDFVTASNLEDL
VEKMNQLTESPLLKVEHVTSQIEARDLQLANKFTKDLQLAAMYNSRKFLGDKLIRTAKPHPILKAENGPLIGVKLHILSR
KTLGGIQTDLSGRVFNQQNVLIKGLYAAGEVAGFGGGGMHGYRALEGTFVGGCLFSGRTVGRSIARGE
>Mature_548_residues
MEANVIVVGAGIAGLVATVEIAQSGKKVILIDQEPESSLGGQAWWSFGGLFLVDSKEQRRLNIKDSYELAWNDWKSTAGF
DRKDDDWGRKWAEAYVQFAASEKREWLRSYGIRFFPVVGWAERGGSLASGHGNSVPRFHIVWGTGPGIVTPFVERMQSYV
KQGLVTYLPRHRAEHLLVQNETVYGVEGSILKGSTAKRGEASNRIVVDSFSFKAENVVVTSGGIGANHELIRKNWPERLG
KPPKNMLSGVPEHVDGKMLEVAEHAGARIVHRDRMWHYTEGIKNWNSVWENHGIRILPGPSSIWLDAEGNRFHAPNYPGF
DTLSTLEAIQNTGYDYSWFILTQKIIEKEFALSGSEQNPDLTNKRISEVLKRAQSGAPEPVQKFLNHGEDFVTASNLEDL
VEKMNQLTESPLLKVEHVTSQIEARDLQLANKFTKDLQLAAMYNSRKFLGDKLIRTAKPHPILKAENGPLIGVKLHILSR
KTLGGIQTDLSGRVFNQQNVLIKGLYAAGEVAGFGGGGMHGYRALEGTFVGGCLFSGRTVGRSIARGE

Specific function: Able to catalyze the elimination of the C-1 and C-2 hydrogen atoms of the A-ring from the polycyclic ring structure of 3-ketosteroids, but the ketosteroid dehydrogenase activity is low compared to KsdD in the cholesterol degradation process. The low activ

COG id: COG3573

COG function: function code R; Predicted oxidoreductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 60714; Mature: 60714

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEANVIVVGAGIAGLVATVEIAQSGKKVILIDQEPESSLGGQAWWSFGGLFLVDSKEQRR
CCCCEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHCCCEEEEECCHHCC
LNIKDSYELAWNDWKSTAGFDRKDDDWGRKWAEAYVQFAASEKREWLRSYGIRFFPVVGW
CCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEH
AERGGSLASGHGNSVPRFHIVWGTGPGIVTPFVERMQSYVKQGLVTYLPRHRAEHLLVQN
HHCCCCEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEC
ETVYGVEGSILKGSTAKRGEASNRIVVDSFSFKAENVVVTSGGIGANHELIRKNWPERLG
CEEECCCCCEEECCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHCCHHHHC
KPPKNMLSGVPEHVDGKMLEVAEHAGARIVHRDRMWHYTEGIKNWNSVWENHGIRILPGP
CCHHHHHCCCCCCCCCHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHCCCEEEEECC
SSIWLDAEGNRFHAPNYPGFDTLSTLEAIQNTGYDYSWFILTQKIIEKEFALSGSEQNPD
CEEEEECCCCEEECCCCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCCCC
LTNKRISEVLKRAQSGAPEPVQKFLNHGEDFVTASNLEDLVEKMNQLTESPLLKVEHVTS
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHCCCHHHHHHHH
QIEARDLQLANKFTKDLQLAAMYNSRKFLGDKLIRTAKPHPILKAENGPLIGVKLHILSR
HHHHHHHHHHHHHHHHHEEEHHHCCHHHHHHHHHHCCCCCCEEEECCCCEEEEEEEEECC
KTLGGIQTDLSGRVFNQQNVLIKGLYAAGEVAGFGGGGMHGYRALEGTFVGGCLFSGRTV
CCCCCCCCCCCCCEECCCCEEEEEEEHHCCCCCCCCCCCCCHHHHCCCEEEEHEECCCHH
GRSIARGE
HHHHCCCC
>Mature Secondary Structure
MEANVIVVGAGIAGLVATVEIAQSGKKVILIDQEPESSLGGQAWWSFGGLFLVDSKEQRR
CCCCEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHCCCEEEEECCHHCC
LNIKDSYELAWNDWKSTAGFDRKDDDWGRKWAEAYVQFAASEKREWLRSYGIRFFPVVGW
CCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEH
AERGGSLASGHGNSVPRFHIVWGTGPGIVTPFVERMQSYVKQGLVTYLPRHRAEHLLVQN
HHCCCCEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEC
ETVYGVEGSILKGSTAKRGEASNRIVVDSFSFKAENVVVTSGGIGANHELIRKNWPERLG
CEEECCCCCEEECCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHCCHHHHC
KPPKNMLSGVPEHVDGKMLEVAEHAGARIVHRDRMWHYTEGIKNWNSVWENHGIRILPGP
CCHHHHHCCCCCCCCCHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHCCCEEEEECC
SSIWLDAEGNRFHAPNYPGFDTLSTLEAIQNTGYDYSWFILTQKIIEKEFALSGSEQNPD
CEEEEECCCCEEECCCCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCCCC
LTNKRISEVLKRAQSGAPEPVQKFLNHGEDFVTASNLEDLVEKMNQLTESPLLKVEHVTS
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHCCCHHHHHHHH
QIEARDLQLANKFTKDLQLAAMYNSRKFLGDKLIRTAKPHPILKAENGPLIGVKLHILSR
HHHHHHHHHHHHHHHHHEEEHHHCCHHHHHHHHHHCCCCCCEEEECCCCEEEEEEEEECC
KTLGGIQTDLSGRVFNQQNVLIKGLYAAGEVAGFGGGGMHGYRALEGTFVGGCLFSGRTV
CCCCCCCCCCCCCEECCCCEEEEEEEHHCCCCCCCCCCCCCHHHHCCCEEEEHEECCCHH
GRSIARGE
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA