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The map label for this gene is yngJ [H]

Identifier: 23099150

GI number: 23099150

Start: 1736827

End: 1737969

Strand: Direct

Name: yngJ [H]

Synonym: OB1695

Alternate gene names: 23099150

Gene position: 1736827-1737969 (Clockwise)

Preceding gene: 23099149

Following gene: 23099151

Centisome position: 47.84

GC content: 39.28

Gene sequence:

>1143_bases
ATGAACTTTGAGCTTACGAAAGAGCAGATTATGATTCGAAAGATGGTTCGTGATTTTGCAGAAACCGTGATCCAACCAAG
AGCTATCGAAATTGATACGAAAGCTGAATTTCCAGAAGATATTTTTAAACAAATGGGAGAGCTAGGATTACTTGGTCTCC
CCTTTCCAGAAGAGTACGGTGGATCAGGCGGAGATACAGTATCATATGCACTTGCGGTAGAAGAGATTGGTCGTATTTGT
GGAAGCACAGGACTCAGTTATGCTGCAGCAGTATCCTTAGGTGCTAGTCCAATTTATTATTTTGGAACAGAACAACAGAA
ATTGGATTTTTTGAAACCGCTTGCATCAGGTGAAGGACTTGGAGCGTTTGGATTAACTGAACCAAATGCCGGATCTGACT
CTGGTGGTACAAAAACAACAGCTAAAGTGGATGGTGATGACTATATCATCAATGGTGAAAAATGTTTTATTACAAATGCC
AGTTATGCAAAATTCATCACTGTTACTGCAGTAACTGAAATAAATAAGGATGGTCGAAATCGAATATCGGCAATCTTGGT
ACCAACAGATACACCGGGGTTAACTATTACAAGTAATTACGACAAAATGGGGGTTAGAGGATCTGATACAGCAGAAATCG
TACTAAATGATGTACGTGTACCACGCAGTAATTTATTGGGTACAGAGCATAAAGGACATCCTCAATTTCTTCAAACGCTA
GATGGAGGAAGAATTTCGATAGCAGCATTAGGGGTTGGTATTGCTCAGGCTGCATTAGATAAAGCTTTAGCATATGCAAA
AGAGCGTAAGCAATTTGGAAAATCTATATCTAACTTTCAAGCGATTCAGTTTAAATTAGCAGATATGGCTATGGAAGTAG
AACTGGCTCGTAATATGGTATTAAAGGCAGCTTGGTTGAAGGATGAAGGAAAGAATTTCTCTAAAGAAGCTGCGTATGCT
AAGCTTTTTGCTACAGAAACGGCTACTCGCTCGGCTAATCAAGCAATTCAGATTCATGGTGGTTACGGATATATGCGTGA
ATATGAAGTAGAAAGATACTTACGTGATGCAAAATTGCTAGAGATTGGCGAAGGAACATCAGAGATTCAAAGGCTTGTAA
TTGCTAGACAGTTAGGATGTTAA

Upstream 100 bases:

>100_bases
TTTGATAAAATAGAAAGTATAATCGAATGTATGATAATTCATAACCATTTGATTTTTATGACTGAGTAACATATGTTGCT
TGAAAAAAGGGAGGATGTAC

Downstream 100 bases:

>100_bases
TGTGAGGAGGATTCTATGATTAAGAGAATGTTGATTGCTAATCGAGGTGAAATTGCTCGGAGAATCATTCGTACATGTAG
ACAATTAAATATTGAAACAA

Product: butyryl-CoA dehydrogenase

Products: 2-butenoyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MNFELTKEQIMIRKMVRDFAETVIQPRAIEIDTKAEFPEDIFKQMGELGLLGLPFPEEYGGSGGDTVSYALAVEEIGRIC
GSTGLSYAAAVSLGASPIYYFGTEQQKLDFLKPLASGEGLGAFGLTEPNAGSDSGGTKTTAKVDGDDYIINGEKCFITNA
SYAKFITVTAVTEINKDGRNRISAILVPTDTPGLTITSNYDKMGVRGSDTAEIVLNDVRVPRSNLLGTEHKGHPQFLQTL
DGGRISIAALGVGIAQAALDKALAYAKERKQFGKSISNFQAIQFKLADMAMEVELARNMVLKAAWLKDEGKNFSKEAAYA
KLFATETATRSANQAIQIHGGYGYMREYEVERYLRDAKLLEIGEGTSEIQRLVIARQLGC

Sequences:

>Translated_380_residues
MNFELTKEQIMIRKMVRDFAETVIQPRAIEIDTKAEFPEDIFKQMGELGLLGLPFPEEYGGSGGDTVSYALAVEEIGRIC
GSTGLSYAAAVSLGASPIYYFGTEQQKLDFLKPLASGEGLGAFGLTEPNAGSDSGGTKTTAKVDGDDYIINGEKCFITNA
SYAKFITVTAVTEINKDGRNRISAILVPTDTPGLTITSNYDKMGVRGSDTAEIVLNDVRVPRSNLLGTEHKGHPQFLQTL
DGGRISIAALGVGIAQAALDKALAYAKERKQFGKSISNFQAIQFKLADMAMEVELARNMVLKAAWLKDEGKNFSKEAAYA
KLFATETATRSANQAIQIHGGYGYMREYEVERYLRDAKLLEIGEGTSEIQRLVIARQLGC
>Mature_380_residues
MNFELTKEQIMIRKMVRDFAETVIQPRAIEIDTKAEFPEDIFKQMGELGLLGLPFPEEYGGSGGDTVSYALAVEEIGRIC
GSTGLSYAAAVSLGASPIYYFGTEQQKLDFLKPLASGEGLGAFGLTEPNAGSDSGGTKTTAKVDGDDYIINGEKCFITNA
SYAKFITVTAVTEINKDGRNRISAILVPTDTPGLTITSNYDKMGVRGSDTAEIVLNDVRVPRSNLLGTEHKGHPQFLQTL
DGGRISIAALGVGIAQAALDKALAYAKERKQFGKSISNFQAIQFKLADMAMEVELARNMVLKAAWLKDEGKNFSKEAAYA
KLFATETATRSANQAIQIHGGYGYMREYEVERYLRDAKLLEIGEGTSEIQRLVIARQLGC

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=377, Percent_Identity=48.2758620689655, Blast_Score=341, Evalue=6e-94,
Organism=Homo sapiens, GI226958412, Length=375, Percent_Identity=40.2666666666667, Blast_Score=272, Evalue=3e-73,
Organism=Homo sapiens, GI4557231, Length=380, Percent_Identity=42.1052631578947, Blast_Score=260, Evalue=1e-69,
Organism=Homo sapiens, GI187960098, Length=380, Percent_Identity=42.1052631578947, Blast_Score=260, Evalue=2e-69,
Organism=Homo sapiens, GI226958414, Length=339, Percent_Identity=41.0029498525074, Blast_Score=255, Evalue=4e-68,
Organism=Homo sapiens, GI4501859, Length=377, Percent_Identity=37.6657824933687, Blast_Score=247, Evalue=2e-65,
Organism=Homo sapiens, GI7656849, Length=375, Percent_Identity=36.8, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI21361497, Length=353, Percent_Identity=38.5269121813031, Blast_Score=227, Evalue=1e-59,
Organism=Homo sapiens, GI4501857, Length=376, Percent_Identity=34.5744680851064, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI76496475, Length=349, Percent_Identity=38.3954154727794, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI4557235, Length=349, Percent_Identity=38.3954154727794, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI4503943, Length=378, Percent_Identity=34.1269841269841, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI7669494, Length=353, Percent_Identity=34.8441926345609, Blast_Score=178, Evalue=9e-45,
Organism=Homo sapiens, GI211971008, Length=357, Percent_Identity=29.4117647058824, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI48976061, Length=357, Percent_Identity=29.4117647058824, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI38505218, Length=347, Percent_Identity=29.971181556196, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI218563752, Length=267, Percent_Identity=25.8426966292135, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI87081958, Length=380, Percent_Identity=33.6842105263158, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1786223, Length=377, Percent_Identity=30.7692307692308, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI87081702, Length=334, Percent_Identity=23.9520958083832, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17569725, Length=380, Percent_Identity=41.0526315789474, Blast_Score=271, Evalue=3e-73,
Organism=Caenorhabditis elegans, GI17534899, Length=381, Percent_Identity=42.257217847769, Blast_Score=271, Evalue=6e-73,
Organism=Caenorhabditis elegans, GI17570075, Length=381, Percent_Identity=40.9448818897638, Blast_Score=263, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI17538396, Length=378, Percent_Identity=38.8888888888889, Blast_Score=259, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI17508101, Length=373, Percent_Identity=37.8016085790885, Blast_Score=259, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI17506239, Length=372, Percent_Identity=36.2903225806452, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI17533517, Length=361, Percent_Identity=34.6260387811634, Blast_Score=217, Evalue=8e-57,
Organism=Caenorhabditis elegans, GI71985184, Length=353, Percent_Identity=35.1274787535411, Blast_Score=205, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI71990804, Length=308, Percent_Identity=37.6623376623377, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17551932, Length=356, Percent_Identity=31.7415730337079, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17534353, Length=377, Percent_Identity=31.8302387267904, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17505929, Length=370, Percent_Identity=30.8108108108108, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI71982178, Length=272, Percent_Identity=35.6617647058824, Blast_Score=164, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI71985192, Length=301, Percent_Identity=32.890365448505, Blast_Score=154, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=36.2068965517241, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17531909, Length=239, Percent_Identity=33.8912133891213, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17562446, Length=330, Percent_Identity=31.8181818181818, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17531913, Length=176, Percent_Identity=33.5227272727273, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI86563383, Length=272, Percent_Identity=25.7352941176471, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI86563381, Length=272, Percent_Identity=25.7352941176471, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356377, Length=372, Percent_Identity=45.6989247311828, Blast_Score=327, Evalue=8e-90,
Organism=Drosophila melanogaster, GI24646207, Length=383, Percent_Identity=45.6919060052219, Blast_Score=310, Evalue=9e-85,
Organism=Drosophila melanogaster, GI24660351, Length=382, Percent_Identity=40.8376963350785, Blast_Score=261, Evalue=7e-70,
Organism=Drosophila melanogaster, GI24666513, Length=372, Percent_Identity=38.9784946236559, Blast_Score=251, Evalue=6e-67,
Organism=Drosophila melanogaster, GI21355753, Length=379, Percent_Identity=39.3139841688654, Blast_Score=249, Evalue=2e-66,
Organism=Drosophila melanogaster, GI281363737, Length=358, Percent_Identity=33.7988826815642, Blast_Score=197, Evalue=9e-51,
Organism=Drosophila melanogaster, GI19920834, Length=382, Percent_Identity=33.2460732984293, Blast_Score=181, Evalue=9e-46,
Organism=Drosophila melanogaster, GI45550141, Length=289, Percent_Identity=24.9134948096886, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI221473076, Length=289, Percent_Identity=24.9134948096886, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.2

Molecular weight: Translated: 41262; Mature: 41262

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFELTKEQIMIRKMVRDFAETVIQPRAIEIDTKAEFPEDIFKQMGELGLLGLPFPEEYG
CCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCEECCCCCHHHC
GSGGDTVSYALAVEEIGRICGSTGLSYAAAVSLGASPIYYFGTEQQKLDFLKPLASGEGL
CCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCC
GAFGLTEPNAGSDSGGTKTTAKVDGDDYIINGEKCFITNASYAKFITVTAVTEINKDGRN
CCCCCCCCCCCCCCCCCCEEEEECCCCEEECCCEEEEECCCCEEEEEEEEEECCCCCCCC
RISAILVPTDTPGLTITSNYDKMGVRGSDTAEIVLNDVRVPRSNLLGTEHKGHPQFLQTL
CEEEEEEECCCCCEEEECCCCCCCCCCCCCCEEEEECCCCCHHHCCCCCCCCCHHHHHHC
DGGRISIAALGVGIAQAALDKALAYAKERKQFGKSISNFQAIQFKLADMAMEVELARNMV
CCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHH
LKAAWLKDEGKNFSKEAAYAKLFATETATRSANQAIQIHGGYGYMREYEVERYLRDAKLL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCEE
EIGEGTSEIQRLVIARQLGC
EECCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNFELTKEQIMIRKMVRDFAETVIQPRAIEIDTKAEFPEDIFKQMGELGLLGLPFPEEYG
CCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCEECCCCCHHHC
GSGGDTVSYALAVEEIGRICGSTGLSYAAAVSLGASPIYYFGTEQQKLDFLKPLASGEGL
CCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCC
GAFGLTEPNAGSDSGGTKTTAKVDGDDYIINGEKCFITNASYAKFITVTAVTEINKDGRN
CCCCCCCCCCCCCCCCCCEEEEECCCCEEECCCEEEEECCCCEEEEEEEEEECCCCCCCC
RISAILVPTDTPGLTITSNYDKMGVRGSDTAEIVLNDVRVPRSNLLGTEHKGHPQFLQTL
CEEEEEEECCCCCEEEECCCCCCCCCCCCCCEEEEECCCCCHHHCCCCCCCCCHHHHHHC
DGGRISIAALGVGIAQAALDKALAYAKERKQFGKSISNFQAIQFKLADMAMEVELARNMV
CCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHH
LKAAWLKDEGKNFSKEAAYAKLFATETATRSANQAIQIHGGYGYMREYEVERYLRDAKLL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCEE
EIGEGTSEIQRLVIARQLGC
EECCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: butanoyl-CoA; acceptor

Specific reaction: butanoyl-CoA + acceptor = 2-butenoyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]