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The map label for this gene is insK [H]

Identifier: 23099091

GI number: 23099091

Start: 1677119

End: 1677973

Strand: Reverse

Name: insK [H]

Synonym: OB1636

Alternate gene names: 23099091

Gene position: 1677973-1677119 (Counterclockwise)

Preceding gene: 23099092

Following gene: 23098982

Centisome position: 46.22

GC content: 37.31

Gene sequence:

>855_bases
TTGGAGCCGGAAATAGTAATTCAACTTGTTAATTCGTTAAAGAAGCAATACCCTGTAAAACTGATTTGTGAGTGTATAGG
GGTACCAAGAGCTACCTATTATCGTTGGGTTCAAAAATCCTGGGAACCAACAGAGCTAGAACAACTTATTATCGATATTT
GTCAATCTTTAAAATACCGTGTTGGCCATCGAATGGTTAAGAAGATGTTGAAAGGGGATCATCATATTCTTGTGAATCGA
AATACGGTTCAACGAATCATGCAAAAGTATAAGATTCAATGTCGCGTCAAACCAAAAAGAAAATCAAAGATCGCAGGCGA
AAGTAAATGTGTTGTACCTAACTTATTGGAACAGAATTTCAAGGCAGAAAGCCCAAACCAAAAGTGGGTTACCGACATTA
CCTACTTGCCTTTTGGAGAATCAATAATGTATCTATCAACGATTATGGATTTGTATAATAACGAGATTGTTGCTTATCAA
GTTAGCCATACCCAAGGGGTAGAACTCGTATTAGATACATTGAAAACAGCATGTAATGGACGTGAAACGAAAGGACTGAT
TCTTCACAGTGATCAGGGATCACAATACACATCGTATGCTTTTCAAGGTTTAGCAGAAGAAAAAGGCATTATCACAAGCA
TGTCCCGCAAAGGCAATTGCTTTGATAATGCCGTCATTGAATCCTTCCACTCCACCATAAAGTCAGAAGAATTCTACACA
CATCAAAAGATGCGTCTTACAAATTCTATTGTACTAGAAAAAGTGGAATCGTACATGTATTATTACAATTATATACGACC
GTTTTCAAAATTAAACTGCCTCTCCCCTGTTCAATTCAGGGAAAAGGCAGCATAG

Upstream 100 bases:

>100_bases
GTCCTGAAGGATTAAGTGAAATAGATCAATTAAAAAGGCAAGTCAACCATTTGGAAATTAAAAATCAAATTTTATAAAAG
TACCGGGAAATCGAAAGGAG

Downstream 100 bases:

>100_bases
GTGCTTTTTCTTGTCTCATATTACTAGGTCAGTTCACTTTATCGCTGCTGGCTTTTTCATTATTCTTTATCGAGTGAAAC
ATTTTTAACCGGTGAGAACG

Product: transposase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MEPEIVIQLVNSLKKQYPVKLICECIGVPRATYYRWVQKSWEPTELEQLIIDICQSLKYRVGHRMVKKMLKGDHHILVNR
NTVQRIMQKYKIQCRVKPKRKSKIAGESKCVVPNLLEQNFKAESPNQKWVTDITYLPFGESIMYLSTIMDLYNNEIVAYQ
VSHTQGVELVLDTLKTACNGRETKGLILHSDQGSQYTSYAFQGLAEEKGIITSMSRKGNCFDNAVIESFHSTIKSEEFYT
HQKMRLTNSIVLEKVESYMYYYNYIRPFSKLNCLSPVQFREKAA

Sequences:

>Translated_284_residues
MEPEIVIQLVNSLKKQYPVKLICECIGVPRATYYRWVQKSWEPTELEQLIIDICQSLKYRVGHRMVKKMLKGDHHILVNR
NTVQRIMQKYKIQCRVKPKRKSKIAGESKCVVPNLLEQNFKAESPNQKWVTDITYLPFGESIMYLSTIMDLYNNEIVAYQ
VSHTQGVELVLDTLKTACNGRETKGLILHSDQGSQYTSYAFQGLAEEKGIITSMSRKGNCFDNAVIESFHSTIKSEEFYT
HQKMRLTNSIVLEKVESYMYYYNYIRPFSKLNCLSPVQFREKAA
>Mature_284_residues
MEPEIVIQLVNSLKKQYPVKLICECIGVPRATYYRWVQKSWEPTELEQLIIDICQSLKYRVGHRMVKKMLKGDHHILVNR
NTVQRIMQKYKIQCRVKPKRKSKIAGESKCVVPNLLEQNFKAESPNQKWVTDITYLPFGESIMYLSTIMDLYNNEIVAYQ
VSHTQGVELVLDTLKTACNGRETKGLILHSDQGSQYTSYAFQGLAEEKGIITSMSRKGNCFDNAVIESFHSTIKSEEFYT
HQKMRLTNSIVLEKVESYMYYYNYIRPFSKLNCLSPVQFREKAA

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=246, Percent_Identity=30.0813008130081, Blast_Score=111, Evalue=9e-25,
Organism=Escherichia coli, GI1789981, Length=283, Percent_Identity=35.3356890459364, Blast_Score=168, Evalue=4e-43,
Organism=Escherichia coli, GI1788405, Length=290, Percent_Identity=29.6551724137931, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1787263, Length=290, Percent_Identity=29.6551724137931, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1786753, Length=290, Percent_Identity=29.6551724137931, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1786570, Length=290, Percent_Identity=29.6551724137931, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1786490, Length=290, Percent_Identity=29.6551724137931, Blast_Score=124, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 33036; Mature: 33036

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPEIVIQLVNSLKKQYPVKLICECIGVPRATYYRWVQKSWEPTELEQLIIDICQSLKYR
CCHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VGHRMVKKMLKGDHHILVNRNTVQRIMQKYKIQCRVKPKRKSKIAGESKCVVPNLLEQNF
HHHHHHHHHHCCCCEEEEECHHHHHHHHHHHEEEEECCHHHHHCCCCCCCCCHHHHHCCC
KAESPNQKWVTDITYLPFGESIMYLSTIMDLYNNEIVAYQVSHTQGVELVLDTLKTACNG
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCC
RETKGLILHSDQGSQYTSYAFQGLAEEKGIITSMSRKGNCFDNAVIESFHSTIKSEEFYT
CCCCCEEEECCCCCHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
HQKMRLTNSIVLEKVESYMYYYNYIRPFSKLNCLSPVQFREKAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCC
>Mature Secondary Structure
MEPEIVIQLVNSLKKQYPVKLICECIGVPRATYYRWVQKSWEPTELEQLIIDICQSLKYR
CCHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VGHRMVKKMLKGDHHILVNRNTVQRIMQKYKIQCRVKPKRKSKIAGESKCVVPNLLEQNF
HHHHHHHHHHCCCCEEEEECHHHHHHHHHHHEEEEECCHHHHHCCCCCCCCCHHHHHCCC
KAESPNQKWVTDITYLPFGESIMYLSTIMDLYNNEIVAYQVSHTQGVELVLDTLKTACNG
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCC
RETKGLILHSDQGSQYTSYAFQGLAEEKGIITSMSRKGNCFDNAVIESFHSTIKSEEFYT
CCCCCEEEECCCCCHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
HQKMRLTNSIVLEKVESYMYYYNYIRPFSKLNCLSPVQFREKAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]