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The map label for this gene is pbuO [H]

Identifier: 23098972

GI number: 23098972

Start: 1560569

End: 1561840

Strand: Reverse

Name: pbuO [H]

Synonym: OB1517

Alternate gene names: 23098972

Gene position: 1561840-1560569 (Counterclockwise)

Preceding gene: 23098982

Following gene: 23098969

Centisome position: 43.02

GC content: 35.06

Gene sequence:

>1272_bases
TTGCAGAGGTTTATTATGGAGCAACATGATTCATTAAGAAAGGAAATCATCGCTGGAGTAATTGGCTTTTTTACAACCGT
TTATATCGTTATTGTGAATGGGTCTATTTTAAGTGAAGCAGGTGTTTCTTTAGAAACTGGAATGATTGCAACGATTATGG
CTAGTTTCGTTGGAACAATGATCATGGGGATATTTGGTAAACTCCCCCTAATACTTATTCCTGGAATGGGTATTAATGCA
TTATTTGCATATTCTATTATCGGTAATAACAACTTCTCATTTCAAGAAGGGCTAGCCATTGTATGGATTGCCGGCCTTAT
ATTTGTTATTACTGCATTCACCCGTTTAGGAACCATCTTAAAAGAAGCTATACCAGACTCATTAAAACATGCTATTACTG
TCGGATTAGGATTTTTCTTAATTCTTATCGGATTAGAAAAAAGCGGGATTGTCATTAGTGGAGATAGCACCGTAATTGCA
ATTGGAGATTTCACATCACCTGCAGTGATTACCGGTTTAGTTACCTTATTTATTGCTATTTTCTTGTTTGTTAAAAATAT
CCCAGCTAATTTTTTAATAACGATGGTAATTGGTACTGTAATCGCGGTGGTAACTGGCGTTGAAACGAGACAAGCTAGCT
CGATACAATTCCAGCTAAACGAATTGATGTTTATACCATCTTTTCAAGCTATTGGAGATATATCCTTTTGGTTGGCAATA
TTTACGCTATCACTAATTCTTATATTTGAAAATATGGGGATATTAAACGGGCAACTCGATATGTTAGATAAACAAAAAGG
GTATAAAAAAGCATTTCGAATTACAGCAACATCTTCGTTGACATCTGCTTTGTTCGGAACTTCTCCAACGGTCTCAAGTG
CTGAGAATGCTGCTGTAATTGCATCAGGTGGAAAAACAGGAAAAGCAGCAATTACTGCAGGGATATTGTTCCTAGCAACG
ATTATATTCATTCCTTGGATATCTTTAGTCCCTAATACAGCAATTAGTCCTATCTTAATTATCGTTGGTTTTCTTATGGC
ACAGAATATAAAGCATTTACCCCTACAGCAACTCGCAGATTGTATTCCAGCTCTGTTAATTGTTGTCATGATACCTTTTA
CTTATAGTATCGGGGATGGAATGGCTTTTGGATTTATTGCTTATCCAATTGTTAAATGGGCTTTAGGTAAAAAAGAAGAA
ATATCAATACCATTGCTAATTATTTCAGGATTATTCTTCTTGGAATTTGCATTTAAAGTAATTGGTATTTAA

Upstream 100 bases:

>100_bases
TAATACTAAGCTAAATTTGACTTTCCTTCTTTCTGTCACTATAATAATTCTTTGTGGATAAAGCATATCGGCTTTATTGG
GCGGGAGAGGGACAGCATGA

Downstream 100 bases:

>100_bases
TTTTTAAATGAGAATGGGACAAAAGTATTCACGCAAAAGACAAATCCGAATGATCGGCCTATGAAAACCCGTTTCAGAAA
TATACTGCGCTTTCCATGGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MQRFIMEQHDSLRKEIIAGVIGFFTTVYIVIVNGSILSEAGVSLETGMIATIMASFVGTMIMGIFGKLPLILIPGMGINA
LFAYSIIGNNNFSFQEGLAIVWIAGLIFVITAFTRLGTILKEAIPDSLKHAITVGLGFFLILIGLEKSGIVISGDSTVIA
IGDFTSPAVITGLVTLFIAIFLFVKNIPANFLITMVIGTVIAVVTGVETRQASSIQFQLNELMFIPSFQAIGDISFWLAI
FTLSLILIFENMGILNGQLDMLDKQKGYKKAFRITATSSLTSALFGTSPTVSSAENAAVIASGGKTGKAAITAGILFLAT
IIFIPWISLVPNTAISPILIIVGFLMAQNIKHLPLQQLADCIPALLIVVMIPFTYSIGDGMAFGFIAYPIVKWALGKKEE
ISIPLLIISGLFFLEFAFKVIGI

Sequences:

>Translated_423_residues
MQRFIMEQHDSLRKEIIAGVIGFFTTVYIVIVNGSILSEAGVSLETGMIATIMASFVGTMIMGIFGKLPLILIPGMGINA
LFAYSIIGNNNFSFQEGLAIVWIAGLIFVITAFTRLGTILKEAIPDSLKHAITVGLGFFLILIGLEKSGIVISGDSTVIA
IGDFTSPAVITGLVTLFIAIFLFVKNIPANFLITMVIGTVIAVVTGVETRQASSIQFQLNELMFIPSFQAIGDISFWLAI
FTLSLILIFENMGILNGQLDMLDKQKGYKKAFRITATSSLTSALFGTSPTVSSAENAAVIASGGKTGKAAITAGILFLAT
IIFIPWISLVPNTAISPILIIVGFLMAQNIKHLPLQQLADCIPALLIVVMIPFTYSIGDGMAFGFIAYPIVKWALGKKEE
ISIPLLIISGLFFLEFAFKVIGI
>Mature_423_residues
MQRFIMEQHDSLRKEIIAGVIGFFTTVYIVIVNGSILSEAGVSLETGMIATIMASFVGTMIMGIFGKLPLILIPGMGINA
LFAYSIIGNNNFSFQEGLAIVWIAGLIFVITAFTRLGTILKEAIPDSLKHAITVGLGFFLILIGLEKSGIVISGDSTVIA
IGDFTSPAVITGLVTLFIAIFLFVKNIPANFLITMVIGTVIAVVTGVETRQASSIQFQLNELMFIPSFQAIGDISFWLAI
FTLSLILIFENMGILNGQLDMLDKQKGYKKAFRITATSSLTSALFGTSPTVSSAENAAVIASGGKTGKAAITAGILFLAT
IIFIPWISLVPNTAISPILIIVGFLMAQNIKHLPLQQLADCIPALLIVVMIPFTYSIGDGMAFGFIAYPIVKWALGKKEE
ISIPLLIISGLFFLEFAFKVIGI

Specific function: Involved in the uptake of the purine bases hypoxanthine and guanine. May work at purine concentrations higher than 100 uM [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=425, Percent_Identity=33.1764705882353, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1790150, Length=429, Percent_Identity=32.6340326340326, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI1790499, Length=422, Percent_Identity=28.9099526066351, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI48994909, Length=431, Percent_Identity=26.2180974477958, Blast_Score=129, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 45335; Mature: 45335

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRFIMEQHDSLRKEIIAGVIGFFTTVYIVIVNGSILSEAGVSLETGMIATIMASFVGTM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHCCCCHHHHHHHHHHHHHHHHH
IMGIFGKLPLILIPGMGINALFAYSIIGNNNFSFQEGLAIVWIAGLIFVITAFTRLGTIL
HHHHHCCCCEEEECCCCHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEAIPDSLKHAITVGLGFFLILIGLEKSGIVISGDSTVIAIGDFTSPAVITGLVTLFIAI
HHHCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEECCCCHHHHHHHHHHHHHH
FLFVKNIPANFLITMVIGTVIAVVTGVETRQASSIQFQLNELMFIPSFQAIGDISFWLAI
HHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEHHHEEECCCHHHHHHHHHHHHH
FTLSLILIFENMGILNGQLDMLDKQKGYKKAFRITATSSLTSALFGTSPTVSSAENAAVI
HHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHEEEEHHHHHHHHHCCCCCCCCCCCCEEE
ASGGKTGKAAITAGILFLATIIFIPWISLVPNTAISPILIIVGFLMAQNIKHLPLQQLAD
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHH
CIPALLIVVMIPFTYSIGDGMAFGFIAYPIVKWALGKKEEISIPLLIISGLFFLEFAFKV
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
IGI
HCC
>Mature Secondary Structure
MQRFIMEQHDSLRKEIIAGVIGFFTTVYIVIVNGSILSEAGVSLETGMIATIMASFVGTM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHCCCCHHHHHHHHHHHHHHHHH
IMGIFGKLPLILIPGMGINALFAYSIIGNNNFSFQEGLAIVWIAGLIFVITAFTRLGTIL
HHHHHCCCCEEEECCCCHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEAIPDSLKHAITVGLGFFLILIGLEKSGIVISGDSTVIAIGDFTSPAVITGLVTLFIAI
HHHCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEECCCCHHHHHHHHHHHHHH
FLFVKNIPANFLITMVIGTVIAVVTGVETRQASSIQFQLNELMFIPSFQAIGDISFWLAI
HHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEHHHEEECCCHHHHHHHHHHHHH
FTLSLILIFENMGILNGQLDMLDKQKGYKKAFRITATSSLTSALFGTSPTVSSAENAAVI
HHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHEEEEHHHHHHHHHCCCCCCCCCCCCEEE
ASGGKTGKAAITAGILFLATIIFIPWISLVPNTAISPILIIVGFLMAQNIKHLPLQQLAD
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHH
CIPALLIVVMIPFTYSIGDGMAFGFIAYPIVKWALGKKEEISIPLLIISGLFFLEFAFKV
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
IGI
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 11591660 [H]