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The map label for this gene is rsgA2

Identifier: 23098965

GI number: 23098965

Start: 1555002

End: 1555883

Strand: Direct

Name: rsgA2

Synonym: OB1510

Alternate gene names: 23098965

Gene position: 1555002-1555883 (Clockwise)

Preceding gene: 23098964

Following gene: 23098966

Centisome position: 42.83

GC content: 34.13

Gene sequence:

>882_bases
ATGGCTGAAGGAAGGATTATAAAAGCGCTGAGTGGCTTTTATTACGTACAATCAGATAATCAACAATTCGTCTGTAAAGG
AAGAGGGTTATTTCGAAACAAGAAAATAACTCCTCTAGTTGGTGATTATGTTGAATTTGAGCCAAAAGATGATAATGAAG
GATATATAATGGAAATCAAAGAGAGGTCGAATGAATTAGTTCGACCTCCTATTGCTAATATCGATCAAGCAATAATAGTA
AGCTCTGCAGTTGATCCTGACTTTACTACGTTACTGCTGGATCGATTTCTAGTATTAATTGAATCCAAGCATATCCAACC
AATAATATTAATTACTAAAGTAGATTTATTAAACGAAGATCAACTTGAAAATATCAAGCTATATAAACAACATTATGAAA
AAATAGGTTATCGAGTGGAATTAGTTTCCTCTAAAAATCAGGATCTTTTGCCTGAATTAGAACCTTATTTTGATGAGAAA
GTATCTGTTTTTGCGGGTCAATCAGGAGTAGGAAAATCATCCTTAATCAATGTGCTAGATCCTTCATTATTATTAGAAAC
TGCAGAAATCTCTAAAAGTCTAGGTAGAGGCAAACACACTACTCGACATGTGGAATTAATGAAAATAGGAAATGGGTTAG
TTGCTGATACACCAGGATTTAGTGTTTTAGAGTTTCGTGAAATTGAAGCAGAAGAATTAGCGGATAGTTTTCCGGAATTT
AACGCTCGCATGCATTTATGTAAATTTAGAGGATGTATGCATGACAAAGAACCAAAGTGTGCAGTGAAAGAAGCTGTAGA
AAACGAAGAAATTGCGGTTTTTCGTTACAATCATTATCTGCGTTTCTTAGAAGAAATACAGACAAGAAAGCCGAGGTATT
AG

Upstream 100 bases:

>100_bases
TTTAATGGTTCCGCCTGATTCAGAGGCAGAGTATAAAGTTACGAGAGATGATGAGGTTATAAAAGAACGAAGTGTTTCAT
ATGAAGGAGAAGAAGATTAG

Downstream 100 bases:

>100_bases
AATGACAAAAATAGCACCATCAATATTATCAGCAGATTTTGCAAAGCTAGGACAAGAAATAAAGGAAGTAGAAGAAGCGG
GTGCAGATTATATCCATGTT

Product: ribosome-associated GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MAEGRIIKALSGFYYVQSDNQQFVCKGRGLFRNKKITPLVGDYVEFEPKDDNEGYIMEIKERSNELVRPPIANIDQAIIV
SSAVDPDFTTLLLDRFLVLIESKHIQPIILITKVDLLNEDQLENIKLYKQHYEKIGYRVELVSSKNQDLLPELEPYFDEK
VSVFAGQSGVGKSSLINVLDPSLLLETAEISKSLGRGKHTTRHVELMKIGNGLVADTPGFSVLEFREIEAEELADSFPEF
NARMHLCKFRGCMHDKEPKCAVKEAVENEEIAVFRYNHYLRFLEEIQTRKPRY

Sequences:

>Translated_293_residues
MAEGRIIKALSGFYYVQSDNQQFVCKGRGLFRNKKITPLVGDYVEFEPKDDNEGYIMEIKERSNELVRPPIANIDQAIIV
SSAVDPDFTTLLLDRFLVLIESKHIQPIILITKVDLLNEDQLENIKLYKQHYEKIGYRVELVSSKNQDLLPELEPYFDEK
VSVFAGQSGVGKSSLINVLDPSLLLETAEISKSLGRGKHTTRHVELMKIGNGLVADTPGFSVLEFREIEAEELADSFPEF
NARMHLCKFRGCMHDKEPKCAVKEAVENEEIAVFRYNHYLRFLEEIQTRKPRY
>Mature_292_residues
AEGRIIKALSGFYYVQSDNQQFVCKGRGLFRNKKITPLVGDYVEFEPKDDNEGYIMEIKERSNELVRPPIANIDQAIIVS
SAVDPDFTTLLLDRFLVLIESKHIQPIILITKVDLLNEDQLENIKLYKQHYEKIGYRVELVSSKNQDLLPELEPYFDEKV
SVFAGQSGVGKSSLINVLDPSLLLETAEISKSLGRGKHTTRHVELMKIGNGLVADTPGFSVLEFREIEAEELADSFPEFN
ARMHLCKFRGCMHDKEPKCAVKEAVENEEIAVFRYNHYLRFLEEIQTRKPRY

Specific function: May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover

COG id: COG1162

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 engC GTPase domain

Homologues:

Organism=Escherichia coli, GI87082381, Length=274, Percent_Identity=39.7810218978102, Blast_Score=176, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSGA2_OCEIH (Q8ER21)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_692431.1
- ProteinModelPortal:   Q8ER21
- SMR:   Q8ER21
- GeneID:   1017775
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1510
- NMPDR:   fig|221109.1.peg.1512
- HOGENOM:   HBG652450
- OMA:   FRDCKHL
- ProtClustDB:   PRK00098
- BioCyc:   OIHE221109:OB1510-MONOMER
- HAMAP:   MF_01820
- InterPro:   IPR010914
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004881
- Gene3D:   G3DSA:2.40.50.140
- TIGRFAMs:   TIGR00157

Pfam domain/function: PF03193 DUF258; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 33617; Mature: 33486

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS50936 ENGC_GTPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEGRIIKALSGFYYVQSDNQQFVCKGRGLFRNKKITPLVGDYVEFEPKDDNEGYIMEIK
CCCCCEEEEECCEEEEECCCCEEEEECCCCCCCCCCCCEECCCEEECCCCCCCCEEEEEE
ERSNELVRPPIANIDQAIIVSSAVDPDFTTLLLDRFLVLIESKHIQPIILITKVDLLNED
CCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCC
QLENIKLYKQHYEKIGYRVELVSSKNQDLLPELEPYFDEKVSVFAGQSGVGKSSLINVLD
HHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCHHHCCCEEEEECCCCCCHHHHHHHCC
PSLLLETAEISKSLGRGKHTTRHVELMKIGNGLVADTPGFSVLEFREIEAEELADSFPEF
HHHHHHHHHHHHHHCCCCCCHHEEEEEEECCCCEECCCCCCEEHHHHCCHHHHHHCCCCH
NARMHLCKFRGCMHDKEPKCAVKEAVENEEIAVFRYNHYLRFLEEIQTRKPRY
HHHHHHHHHHCCCCCCCCCHHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AEGRIIKALSGFYYVQSDNQQFVCKGRGLFRNKKITPLVGDYVEFEPKDDNEGYIMEIK
CCCCEEEEECCEEEEECCCCEEEEECCCCCCCCCCCCEECCCEEECCCCCCCCEEEEEE
ERSNELVRPPIANIDQAIIVSSAVDPDFTTLLLDRFLVLIESKHIQPIILITKVDLLNED
CCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCC
QLENIKLYKQHYEKIGYRVELVSSKNQDLLPELEPYFDEKVSVFAGQSGVGKSSLINVLD
HHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCHHHCCCEEEEECCCCCCHHHHHHHCC
PSLLLETAEISKSLGRGKHTTRHVELMKIGNGLVADTPGFSVLEFREIEAEELADSFPEF
HHHHHHHHHHHHHHCCCCCCHHEEEEEEECCCCEECCCCCCEEHHHHCCHHHHHHCCCCH
NARMHLCKFRGCMHDKEPKCAVKEAVENEEIAVFRYNHYLRFLEEIQTRKPRY
HHHHHHHHHHCCCCCCCCCHHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376