Click here to switch to the map view.

The map label for this gene is comK [H]

Identifier: 23098632

GI number: 23098632

Start: 1228038

End: 1228547

Strand: Direct

Name: comK [H]

Synonym: OB1177

Alternate gene names: 23098632

Gene position: 1228038-1228547 (Clockwise)

Preceding gene: 23098631

Following gene: 23098634

Centisome position: 33.83

GC content: 37.65

Gene sequence:

>510_bases
ATGAAGAAACAGCAATATCTAGAAATCACGCCATTTACATTGGCGGTCGTATCGGAGCAAGATGAAAATGGAAGATATAT
TGCAAAAGTATTAGAAGAGGAGGCGGAATATGTTTTGGAAGCGAAACCTACCAATGTCATTGATTATGCTTGCAAGTATT
TCGGGGCTAGTTTGAAAGGGCGTCAAGAGGGAACAAGAGAAATTAGTGGAATAACACATAAAGCACCAATAACAATTGAT
CCTGCAAGTGGGATGTATTTCTTCCCAACAAAGTCTCCTAGTAATGCTAACTGTTCTTGGATCGCACATAGTCATATTAA
AGAAGTGCGTAGAGAAGAAGAGGGAAAAACAAGTGTACTATTTAAAAATGGTTCGAAAATTTCACTTGATATTTCCCATG
GTTCTTTAATCAATCAACTACAACGTACCGCGCAAATAAGATTTCTTTTAGACGATCGAATTAAACGTTGGAGGAAGCCT
CCTCATTCTGAAGACGATAAAGACTCTTAA

Upstream 100 bases:

>100_bases
TAACTATTTATTCTAAAAATTATGTAAAAATATATCATTTTTACTAATAATATGTTATATTAGGTATTAAGTCACTATAA
TTGGTAAGGGAGGTTAATAA

Downstream 100 bases:

>100_bases
ACATTAACTCCTGTAGTAATTTTTCAACTTTTTTACGAATAGCTGGGTTAAAATAACTTTTCTTTTCTTCTTTTCCTTGG
CATATAAATAAAAAATTTGA

Product: competence transcription factor

Products: NA

Alternate protein names: CTF; Competence protein K [H]

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MKKQQYLEITPFTLAVVSEQDENGRYIAKVLEEEAEYVLEAKPTNVIDYACKYFGASLKGRQEGTREISGITHKAPITID
PASGMYFFPTKSPSNANCSWIAHSHIKEVRREEEGKTSVLFKNGSKISLDISHGSLINQLQRTAQIRFLLDDRIKRWRKP
PHSEDDKDS

Sequences:

>Translated_169_residues
MKKQQYLEITPFTLAVVSEQDENGRYIAKVLEEEAEYVLEAKPTNVIDYACKYFGASLKGRQEGTREISGITHKAPITID
PASGMYFFPTKSPSNANCSWIAHSHIKEVRREEEGKTSVLFKNGSKISLDISHGSLINQLQRTAQIRFLLDDRIKRWRKP
PHSEDDKDS
>Mature_169_residues
MKKQQYLEITPFTLAVVSEQDENGRYIAKVLEEEAEYVLEAKPTNVIDYACKYFGASLKGRQEGTREISGITHKAPITID
PASGMYFFPTKSPSNANCSWIAHSHIKEVRREEEGKTSVLFKNGSKISLDISHGSLINQLQRTAQIRFLLDDRIKRWRKP
PHSEDDKDS

Specific function: Intermediate regulatory gene required for the expression of the late competence genes comC, comE, comG and the bdbDC operon. Receives signals from SrfA, and possibly other regulatory COM genes, and transduces these signals to the late COM genes [H]

COG id: COG4903

COG function: function code K; Genetic competence transcription factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010461 [H]

Pfam domain/function: PF06338 ComK [H]

EC number: NA

Molecular weight: Translated: 19257; Mature: 19257

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQQYLEITPFTLAVVSEQDENGRYIAKVLEEEAEYVLEAKPTNVIDYACKYFGASLKG
CCCCCEEEECCEEEEEEECCCCCCHHHHHHHHHHHHHEECCCCCHHHHHHHHHHCCCCCC
RQEGTREISGITHKAPITIDPASGMYFFPTKSPSNANCSWIAHSHIKEVRREEEGKTSVL
CCCCHHHHCCCCCCCCEEECCCCCEEEEECCCCCCCCEEEEEHHHHHHHHHHCCCCEEEE
FKNGSKISLDISHGSLINQLQRTAQIRFLLDDRIKRWRKPPHSEDDKDS
EECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKKQQYLEITPFTLAVVSEQDENGRYIAKVLEEEAEYVLEAKPTNVIDYACKYFGASLKG
CCCCCEEEECCEEEEEEECCCCCCHHHHHHHHHHHHHEECCCCCHHHHHHHHHHCCCCCC
RQEGTREISGITHKAPITIDPASGMYFFPTKSPSNANCSWIAHSHIKEVRREEEGKTSVL
CCCCHHHHCCCCCCCCEEECCCCCEEEEECCCCCCCCEEEEEHHHHHHHHHHCCCCEEEE
FKNGSKISLDISHGSLINQLQRTAQIRFLLDDRIKRWRKPPHSEDDKDS
EECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8196543; 9579061; 9384377; 7783616; 11744713 [H]