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The map label for this gene is htrA [H]

Identifier: 23098555

GI number: 23098555

Start: 1154751

End: 1155563

Strand: Direct

Name: htrA [H]

Synonym: OB1100

Alternate gene names: 23098555

Gene position: 1154751-1155563 (Clockwise)

Preceding gene: 23098554

Following gene: 23098556

Centisome position: 31.81

GC content: 35.18

Gene sequence:

>813_bases
GTGGATTCAAAAAATAATAAGAATAATCATGATATCATTGATGATGATTTATATGAAGAAATAGATGAAGAAGAACTTCA
TGAATTGGTAAAAGAAGAGCAAAGAAAGGCTATTGAACGTTCAAAAAATAAAAAAGCAGCCCCAAAGCGTCCATTTCCCA
AATGGATGTTTTGGGTGATTGCTGTAGCGATGACGTTTAATGTTCTGGCTTTTTTCCCTCAAATCATATCCATCCCAGCA
ATTGACTTTTTACAGACATCATCTACATTATCACAAAATAAAGATATACAAGCATTTAAGGAAGCAGTCGTTGTAGTTGA
AACGGATGAAGGTAAAGGTACAGGGTTTTCTATAAATCAACAAGGTAAAATCCTTACAAATGAACATGTAGTAGAAGGAT
ATGACACTGTTATTGTTTCTTTTCCAGAGTTAGGCCTATATGAAGCGGAGGTAGTTGAACGCTATCCGGAAATTGATGTG
GCGGTTTTACAGACCGAAGATGAAGAAGCGTTTCCTTACCTAACCATTGATGATCAATATCAAGTATCTCAAAGTGAAGA
CATTCGTTTTATAGGTAATCCACTATTCTTTAATGGAATTGCCAATGAAGGAAATATCGCTGGTACTGTAAAGTTAGATA
GCTGGGACAAAGAAGTGATGATGATTCAAGCACCCGTCTACAGAGGAAATAGTGGTAGTCCGATAATTAATAAAGCTGGT
GATGTAATTGGAGTGATTTTTGCTACACTAGATCATCAATCAAATGGTAGGGTAGGTTTATATGTACCTATTTCCTATTT
TACAGAAATGTAA

Upstream 100 bases:

>100_bases
ACACTGATTAAAGAGAAAGGTTATTATTACGAAATGTATCAAATGCAGCAAGGATCACTGAGAGCAAACGTTTCTTAAAA
TAAGTTTGATGAGGTGCTTC

Downstream 100 bases:

>100_bases
CAAACTAAAAAAATTGTTTAGCACGTTCAGAGAAGGGTATTTATATACTATAACCTTGCTGGAGGTGCTTTTATGCTATA
TAGCTCAAATATTAAAGAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MDSKNNKNNHDIIDDDLYEEIDEEELHELVKEEQRKAIERSKNKKAAPKRPFPKWMFWVIAVAMTFNVLAFFPQIISIPA
IDFLQTSSTLSQNKDIQAFKEAVVVVETDEGKGTGFSINQQGKILTNEHVVEGYDTVIVSFPELGLYEAEVVERYPEIDV
AVLQTEDEEAFPYLTIDDQYQVSQSEDIRFIGNPLFFNGIANEGNIAGTVKLDSWDKEVMMIQAPVYRGNSGSPIINKAG
DVIGVIFATLDHQSNGRVGLYVPISYFTEM

Sequences:

>Translated_270_residues
MDSKNNKNNHDIIDDDLYEEIDEEELHELVKEEQRKAIERSKNKKAAPKRPFPKWMFWVIAVAMTFNVLAFFPQIISIPA
IDFLQTSSTLSQNKDIQAFKEAVVVVETDEGKGTGFSINQQGKILTNEHVVEGYDTVIVSFPELGLYEAEVVERYPEIDV
AVLQTEDEEAFPYLTIDDQYQVSQSEDIRFIGNPLFFNGIANEGNIAGTVKLDSWDKEVMMIQAPVYRGNSGSPIINKAG
DVIGVIFATLDHQSNGRVGLYVPISYFTEM
>Mature_270_residues
MDSKNNKNNHDIIDDDLYEEIDEEELHELVKEEQRKAIERSKNKKAAPKRPFPKWMFWVIAVAMTFNVLAFFPQIISIPA
IDFLQTSSTLSQNKDIQAFKEAVVVVETDEGKGTGFSINQQGKILTNEHVVEGYDTVIVSFPELGLYEAEVVERYPEIDV
AVLQTEDEEAFPYLTIDDQYQVSQSEDIRFIGNPLFFNGIANEGNIAGTVKLDSWDKEVMMIQAPVYRGNSGSPIINKAG
DVIGVIFATLDHQSNGRVGLYVPISYFTEM

Specific function: A putative protease, its function overlaps that of the related putative proteases HhoA and HhoB [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential). Cell outer membrane (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1789630, Length=165, Percent_Identity=24.8484848484848, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 30480; Mature: 30480

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSKNNKNNHDIIDDDLYEEIDEEELHELVKEEQRKAIERSKNKKAAPKRPFPKWMFWVI
CCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
AVAMTFNVLAFFPQIISIPAIDFLQTSSTLSQNKDIQAFKEAVVVVETDEGKGTGFSINQ
HHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHCCCCHHHHHCEEEEEECCCCCCCCEEECC
QGKILTNEHVVEGYDTVIVSFPELGLYEAEVVERYPEIDVAVLQTEDEEAFPYLTIDDQY
CCCEECCCEEECCCCEEEEECCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCEEEECCCE
QVSQSEDIRFIGNPLFFNGIANEGNIAGTVKLDSWDKEVMMIQAPVYRGNSGSPIINKAG
ECCCCCCEEEECCEEEEECCCCCCCEEEEEEECCCCCEEEEEEECEEECCCCCCCHHCCC
DVIGVIFATLDHQSNGRVGLYVPISYFTEM
HHEEEEEEEECCCCCCCEEEEEEHHHHHCC
>Mature Secondary Structure
MDSKNNKNNHDIIDDDLYEEIDEEELHELVKEEQRKAIERSKNKKAAPKRPFPKWMFWVI
CCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
AVAMTFNVLAFFPQIISIPAIDFLQTSSTLSQNKDIQAFKEAVVVVETDEGKGTGFSINQ
HHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHCCCCHHHHHCEEEEEECCCCCCCCEEECC
QGKILTNEHVVEGYDTVIVSFPELGLYEAEVVERYPEIDVAVLQTEDEEAFPYLTIDDQY
CCCEECCCEEECCCCEEEEECCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCEEEECCCE
QVSQSEDIRFIGNPLFFNGIANEGNIAGTVKLDSWDKEVMMIQAPVYRGNSGSPIINKAG
ECCCCCCEEEECCEEEEECCCCCCCEEEEEEECCCCCEEEEEEECEEECCCCCCCHHCCC
DVIGVIFATLDHQSNGRVGLYVPISYFTEM
HHEEEEEEEECCCCCCCEEEEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]