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The map label for this gene is adeC

Identifier: 23098485

GI number: 23098485

Start: 1070099

End: 1071847

Strand: Direct

Name: adeC

Synonym: OB1030

Alternate gene names: 23098485

Gene position: 1070099-1071847 (Clockwise)

Preceding gene: 23098484

Following gene: 23098486

Centisome position: 29.48

GC content: 36.13

Gene sequence:

>1749_bases
GTGAACAGTACAATTGAACAGTTGAAACATAGAATTGCTGTAGCTAGTAAACGTAAACCAGCTGAACTTGTCATAAAAAA
TGCAGAAGTGTTAAATGTATTTACTGGAGATTGGAAGAAGACGGATGTAGCTATTGCGGATGGTTACATCGCGGGGCTAG
GTAATTATGAAGGTTTGCAAACGGTTGATGCTACAGGCAAAAAAATCGTTCCTGGGCTTATAAATGGACATATACATATT
GAAAGTACCATGTTGACGCCTAGAGAATTTTCAAAAGTAATGTTAAAACATGGGGTAACGACAGCTATTACAGATCCTCA
TGAAATTGCGAATGTCGCAGGAACAGATGGTCTAGAATATATGCTAAATGCTTCCGATGCTTTGCCAATGAACATCTTTG
TTAATATGCCTTCAAGTGTACCCGCGACACAATTTGAACATAATGGCGCACAACTTGATGCAAAAGATATATCTTCTTAC
TTTCAAAATCCAAATGTTCTTGGACTGGCTGAAGTGATGGATTTTCCTTCCGTTGCGAATGCTGATCAAAAAATGTTGGA
AAAGATAGTTAGTACAATTCAACATGGTGGTATTATTGATGGTCATGCGGCTGGATTATCGAAAGAAGATTTAAATATTT
ACATGGCTGCTGGCATTCGAAATGACCATGAATCAGTTTCTGCACAGGAAGGGAAAGATAGACTTGAAGCAGGAATGTAT
CTGATGATACGAGAAGGAACTGTAGCCAAAGATTTGGAAGCTTTATTACCAATTATTAACGATAAAAACGCAAGACGTTG
TATATTTGTTACTGATGATATGTTATTAGATGATTTAGTAGAGAATGGAGATATCGATCACATTATACGTAAAGCCATTC
AATTAGGATTAGATCCGGTTATGGCCTACCAGATGGCTACATTAAATACAGCTGAATGTTTTGGTTTAAGAGAACTTGGA
GCAGTTGCACCCGGATATATAGCAGATTTTTTAATTTTGAATGATGAAAACCAAGTGGATATTCATCAAGTATATAAAAA
TGGGAAGTGTGTAGTGGACGAAGGAGAAATAAATCAGTCGTATTTTGCTGCTTCTCTCACTTATGATGCTACTACATTAC
CAAAACCCCGTATTCAGCAATTGAAAGCAAGTGATTTCTCCATTGATCTTACAGATGATTATTGTAATATCATCGAGATT
GTACCAAATAAAATTATTACCAACCATGTTTGTGAGAGAGTAGAGGTCAAAGAAGGGAAGTTCGTACCATCTGTAGATAA
AGACCAATTACTGATAGCGGTAGTGGAGAGACATAAAGGTCTTGGATATATTGGAAAAGGAATAGTGAAAGGTTTTAAAA
TGAAAGAAGGAGCCATAGCAACATCTGTGGCACATGATTCACATAATTTTGTCGTAGTAGGTACTTCTGAAGAAGAAATG
CTTTCAGCAATAAAAAAAGTAGAACAACTTGATGGTGGTTTAGTAGTAACAAAGCGGAAACAGGTTAAAGCTCACCTAGC
ACTCCCGATTGGGGGATTAATGTCAGATAAAGATTACCTGGATGCTTATGAAGAAGTTTTAAAGTTAAATCATGTAGCAG
TAGAAAATGGTATACCATCGAACTTTAATCCATTTTTAACGTTATCCTTTTTGACTCTACCTGTAATACCGACACTTAAA
GTTACAGATCAAGGGTTATTTGATTTTAAGACCTTTTCTCACATTAATGTAGAAGTAGAAGAGAAATAG

Upstream 100 bases:

>100_bases
TATTGATTAGGAATGCTATTAAAAGACATCTAGACTTGTGAGGAGGCTGTATTCATGCGTATAATATACAACAAGTTATA
AGAAGGTGAGTGGTTCAAAG

Downstream 100 bases:

>100_bases
TTTTAAATAAATTAAGGGAAAAGTGTTCATAAATTTTGTACGGAGAAGGTCTCTTTTAGACAACAATCTATAAGAGTCTT
TCTTGTTCTTTTTTTAAAGA

Product: adenine deaminase

Products: NA

Alternate protein names: Adenase; Adenine aminase

Number of amino acids: Translated: 582; Mature: 582

Protein sequence:

>582_residues
MNSTIEQLKHRIAVASKRKPAELVIKNAEVLNVFTGDWKKTDVAIADGYIAGLGNYEGLQTVDATGKKIVPGLINGHIHI
ESTMLTPREFSKVMLKHGVTTAITDPHEIANVAGTDGLEYMLNASDALPMNIFVNMPSSVPATQFEHNGAQLDAKDISSY
FQNPNVLGLAEVMDFPSVANADQKMLEKIVSTIQHGGIIDGHAAGLSKEDLNIYMAAGIRNDHESVSAQEGKDRLEAGMY
LMIREGTVAKDLEALLPIINDKNARRCIFVTDDMLLDDLVENGDIDHIIRKAIQLGLDPVMAYQMATLNTAECFGLRELG
AVAPGYIADFLILNDENQVDIHQVYKNGKCVVDEGEINQSYFAASLTYDATTLPKPRIQQLKASDFSIDLTDDYCNIIEI
VPNKIITNHVCERVEVKEGKFVPSVDKDQLLIAVVERHKGLGYIGKGIVKGFKMKEGAIATSVAHDSHNFVVVGTSEEEM
LSAIKKVEQLDGGLVVTKRKQVKAHLALPIGGLMSDKDYLDAYEEVLKLNHVAVENGIPSNFNPFLTLSFLTLPVIPTLK
VTDQGLFDFKTFSHINVEVEEK

Sequences:

>Translated_582_residues
MNSTIEQLKHRIAVASKRKPAELVIKNAEVLNVFTGDWKKTDVAIADGYIAGLGNYEGLQTVDATGKKIVPGLINGHIHI
ESTMLTPREFSKVMLKHGVTTAITDPHEIANVAGTDGLEYMLNASDALPMNIFVNMPSSVPATQFEHNGAQLDAKDISSY
FQNPNVLGLAEVMDFPSVANADQKMLEKIVSTIQHGGIIDGHAAGLSKEDLNIYMAAGIRNDHESVSAQEGKDRLEAGMY
LMIREGTVAKDLEALLPIINDKNARRCIFVTDDMLLDDLVENGDIDHIIRKAIQLGLDPVMAYQMATLNTAECFGLRELG
AVAPGYIADFLILNDENQVDIHQVYKNGKCVVDEGEINQSYFAASLTYDATTLPKPRIQQLKASDFSIDLTDDYCNIIEI
VPNKIITNHVCERVEVKEGKFVPSVDKDQLLIAVVERHKGLGYIGKGIVKGFKMKEGAIATSVAHDSHNFVVVGTSEEEM
LSAIKKVEQLDGGLVVTKRKQVKAHLALPIGGLMSDKDYLDAYEEVLKLNHVAVENGIPSNFNPFLTLSFLTLPVIPTLK
VTDQGLFDFKTFSHINVEVEEK
>Mature_582_residues
MNSTIEQLKHRIAVASKRKPAELVIKNAEVLNVFTGDWKKTDVAIADGYIAGLGNYEGLQTVDATGKKIVPGLINGHIHI
ESTMLTPREFSKVMLKHGVTTAITDPHEIANVAGTDGLEYMLNASDALPMNIFVNMPSSVPATQFEHNGAQLDAKDISSY
FQNPNVLGLAEVMDFPSVANADQKMLEKIVSTIQHGGIIDGHAAGLSKEDLNIYMAAGIRNDHESVSAQEGKDRLEAGMY
LMIREGTVAKDLEALLPIINDKNARRCIFVTDDMLLDDLVENGDIDHIIRKAIQLGLDPVMAYQMATLNTAECFGLRELG
AVAPGYIADFLILNDENQVDIHQVYKNGKCVVDEGEINQSYFAASLTYDATTLPKPRIQQLKASDFSIDLTDDYCNIIEI
VPNKIITNHVCERVEVKEGKFVPSVDKDQLLIAVVERHKGLGYIGKGIVKGFKMKEGAIATSVAHDSHNFVVVGTSEEEM
LSAIKKVEQLDGGLVVTKRKQVKAHLALPIGGLMSDKDYLDAYEEVLKLNHVAVENGIPSNFNPFLTLSFLTLPVIPTLK
VTDQGLFDFKTFSHINVEVEEK

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family

Homologues:

Organism=Escherichia coli, GI1790098, Length=602, Percent_Identity=37.7076411960133, Blast_Score=371, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADEC_OCEIH (Q8CUS7)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_691951.1
- ProteinModelPortal:   Q8CUS7
- GeneID:   1016889
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1030
- NMPDR:   fig|221109.1.peg.1032
- HOGENOM:   HBG725357
- OMA:   LHIHYML
- BioCyc:   OIHE221109:OB1030-MONOMER
- BRENDA:   3.5.4.2
- HAMAP:   MF_01518
- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01178

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.4.2

Molecular weight: Translated: 63825; Mature: 63825

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSTIEQLKHRIAVASKRKPAELVIKNAEVLNVFTGDWKKTDVAIADGYIAGLGNYEGLQ
CCCHHHHHHHHHHHHCCCCCHHEEEECCEEEEEEECCCCCCEEEEECCEEEECCCCCCCE
TVDATGKKIVPGLINGHIHIESTMLTPREFSKVMLKHGVTTAITDPHEIANVAGTDGLEY
EECCCCCEECCHHHCCEEEEEEEECCHHHHHHHHHHCCCEEECCCHHHHHHCCCCCCHHH
MLNASDALPMNIFVNMPSSVPATQFEHNGAQLDAKDISSYFQNPNVLGLAEVMDFPSVAN
HCCCCCCCEEEEEEECCCCCCCCCCCCCCCEECHHHHHHHHCCCCEEEHHHHHCCCCCCC
ADQKMLEKIVSTIQHGGIIDGHAAGLSKEDLNIYMAAGIRNDHESVSAQEGKDRLEAGMY
HHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCEEEEEECCCCCCHHCCHHCCHHHHCCCEE
LMIREGTVAKDLEALLPIINDKNARRCIFVTDDMLLDDLVENGDIDHIIRKAIQLGLDPV
EEEECCCHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHCCCCHHHHHHHHHHHCCCHH
MAYQMATLNTAECFGLRELGAVAPGYIADFLILNDENQVDIHQVYKNGKCVVDEGEINQS
HHHHHHHCCHHHHCCHHHHCCCCCCCCEEEEEECCCCCEEHHHHHCCCCEEEECCCCCCC
YFAASLTYDATTLPKPRIQQLKASDFSIDLTDDYCNIIEIVPNKIITNHVCERVEVKEGK
EEEEEEEECCCCCCCHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
FVPSVDKDQLLIAVVERHKGLGYIGKGIVKGFKMKEGAIATSVAHDSHNFVVVGTSEEEM
CCCCCCCCCEEHEEHHHCCCCCHHHHHHHHCCEECCCCEEEEEEECCCCEEEEECCHHHH
LSAIKKVEQLDGGLVVTKRKQVKAHLALPIGGLMSDKDYLDAYEEVLKLNHVAVENGIPS
HHHHHHHHHHCCCEEEEECHHCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHEECCCCCC
NFNPFLTLSFLTLPVIPTLKVTDQGLFDFKTFSHINVEVEEK
CCCCCEEEEEHHHCCCCEEEECCCCCEEEEEEEEEEEEEECC
>Mature Secondary Structure
MNSTIEQLKHRIAVASKRKPAELVIKNAEVLNVFTGDWKKTDVAIADGYIAGLGNYEGLQ
CCCHHHHHHHHHHHHCCCCCHHEEEECCEEEEEEECCCCCCEEEEECCEEEECCCCCCCE
TVDATGKKIVPGLINGHIHIESTMLTPREFSKVMLKHGVTTAITDPHEIANVAGTDGLEY
EECCCCCEECCHHHCCEEEEEEEECCHHHHHHHHHHCCCEEECCCHHHHHHCCCCCCHHH
MLNASDALPMNIFVNMPSSVPATQFEHNGAQLDAKDISSYFQNPNVLGLAEVMDFPSVAN
HCCCCCCCEEEEEEECCCCCCCCCCCCCCCEECHHHHHHHHCCCCEEEHHHHHCCCCCCC
ADQKMLEKIVSTIQHGGIIDGHAAGLSKEDLNIYMAAGIRNDHESVSAQEGKDRLEAGMY
HHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCEEEEEECCCCCCHHCCHHCCHHHHCCCEE
LMIREGTVAKDLEALLPIINDKNARRCIFVTDDMLLDDLVENGDIDHIIRKAIQLGLDPV
EEEECCCHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHCCCCHHHHHHHHHHHCCCHH
MAYQMATLNTAECFGLRELGAVAPGYIADFLILNDENQVDIHQVYKNGKCVVDEGEINQS
HHHHHHHCCHHHHCCHHHHCCCCCCCCEEEEEECCCCCEEHHHHHCCCCEEEECCCCCCC
YFAASLTYDATTLPKPRIQQLKASDFSIDLTDDYCNIIEIVPNKIITNHVCERVEVKEGK
EEEEEEEECCCCCCCHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
FVPSVDKDQLLIAVVERHKGLGYIGKGIVKGFKMKEGAIATSVAHDSHNFVVVGTSEEEM
CCCCCCCCCEEHEEHHHCCCCCHHHHHHHHCCEECCCCEEEEEEECCCCEEEEECCHHHH
LSAIKKVEQLDGGLVVTKRKQVKAHLALPIGGLMSDKDYLDAYEEVLKLNHVAVENGIPS
HHHHHHHHHHCCCEEEEECHHCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHEECCCCCC
NFNPFLTLSFLTLPVIPTLKVTDQGLFDFKTFSHINVEVEEK
CCCCCEEEEEHHHCCCCEEEECCCCCEEEEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376