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The map label for this gene is zraR [H]

Identifier: 23098465

GI number: 23098465

Start: 1052689

End: 1054443

Strand: Direct

Name: zraR [H]

Synonym: OB1010

Alternate gene names: 23098465

Gene position: 1052689-1054443 (Clockwise)

Preceding gene: 23098464

Following gene: 23098466

Centisome position: 29.0

GC content: 32.82

Gene sequence:

>1755_bases
ATGATTAAAACAATGTTAATTGCCCCATATTCTGGTATGGCTGAGTCTGTAAAACAACTTAAACTTCCTGAAGATTTCCA
AGTAGATATTGAAATTGCTAACTTAGAAGACGCAATTCAACTAGCTAAGAGTGTTGAAGATCAAGGGTATGATTTGATTA
TCAGTCGTGGTGGTACCGCAGCTATGATTCAAGAAAAAGTTTCGATACCAGTTATTCATATAGATATTAGCGGGTATGAT
ATGCTTCGTGTATTTACTTTAATTCAAGACACACACCATCGTGTTGCGCTTGTAGGATTTGAGAATATTAGTAGAGGCGC
AAAGACGTTGAGCAGCATATTAGAATATGAAATTGAAATGTTTACGATAAGCCATCGAGATCAAGTTCGTTCTCAATTAG
AAGAGTTAAAAAGACTTGGTTATACTATCGTTATTGGAGACGTTGTAACGGTTGAAGAAGCTCAAAAATTAGGAATAAGA
GGTATTTTAATCACTTCAGGTAAAGAAGCTATTCTTGACGCTTTTGACGAAGGAAGAAGACAGTATCAATTATTAAAGCG
GGCACATGCGAGGGTATCCCGCTATCATCAGATTCTTCAATCGATTCCATCGAATATTATCTTGGTAAATAAAGAGTCAA
AAATAGAATTCTCAAATCTCTCTAGTGAATACGATGAATTAGTAAATGAAATTATCGAATCCAAGGAAATAAATCAACTA
GTAGTAAAAGTGTTTAAAGAAAAGAGATCTTATTGGAAAACCATAGAAACTAAAAAATTTAACATAGATATGCAAATTTT
TCCGATTAAACAAGATAATTCTTTAATCGGAATATATATACAAGCACTCAATAAGTTAGAGGATATAAGCTCGATTAAAA
TGACGAGCAAAGTAGTTCATGTGCCTATTATAGGCGATAGTCCTTATGCGGAAACTTTAAGAGAGACTGTACACCAATTT
GCCCAAGCTAATGAAAACATTCTTATAACCGGTGAACAATCTACGGGCAAAATGACCATCGCAAAAGCTATACATTTTGC
AACATTTGGTCAGGATGCTCCAATGCTTGTTGTAGATTGCAGTTCAATTAAAGAGGGCATCCAAAATTTAGTTGAAAAAG
TACAAATGATTCAACATGGTACAATTGTATTTAAAGAAATAGATCGTCTCTCCATTAAAGAGCAAGAGCTATTAGTTAAT
CTTGTTCAAAACACACCTAGTAGTTTTCAAATTATTTCACTATCAGAGCAGGATTTAGATTCTATGCTTGAGGCCGAGCT
ATTTAATTCGGACTTATACCATTTAATTTCTGAACTATCATTCTATACGAAGCCATTAAGAGAACGAAAAGAAGATATAG
CTGCATTTATCTCTTATTTCTTATCGGAATTTCATACGCACAGTGGAAATGAAACACTGGGTATAAGAAAATCGTCAATC
GATATGTTAAAAGAGTTTGAGTGGCATGGGAATCTAGGTGAATTGCAGAGAAGGGTAAAAGAATTAAGTATAAAAGCAAC
AGGGTATTATATTAATGAAGATCATATTATTGAACTATCAGAAAGAAAAGATAAACAAAAAAAGAATGATTTGATGGATC
GAGATAATTATATTTCAATCAAAGGAACTTTAGAAGAAATAGAACAAGCAATTATTCATAAAGTCTATGAAGATGAAAAT
AGAAATCAAACCAAAACAGCAAAAAGATTAGGAATTAATCGTACAACCCTTTGGAGAAAACTGAATAATACGTAA

Upstream 100 bases:

>100_bases
ACGTCGTTATAGTATACATTATTTGTTAACCATTTGCATGAGCCCACAAAAGTATGGCATAATAGTGTTGTTGAAAAATG
CAACATAAGTAGGTGTAGAA

Downstream 100 bases:

>100_bases
AACAAAGAGAGCCTATTCATATTTGAAGGCTCTCTTTTGTTGCATTATTAAACAAATAATTACATTAATAAATAAATTTC
TGCTGTTTTTTCAAAAAAAT

Product: sigma-L-dependent transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 584; Mature: 584

Protein sequence:

>584_residues
MIKTMLIAPYSGMAESVKQLKLPEDFQVDIEIANLEDAIQLAKSVEDQGYDLIISRGGTAAMIQEKVSIPVIHIDISGYD
MLRVFTLIQDTHHRVALVGFENISRGAKTLSSILEYEIEMFTISHRDQVRSQLEELKRLGYTIVIGDVVTVEEAQKLGIR
GILITSGKEAILDAFDEGRRQYQLLKRAHARVSRYHQILQSIPSNIILVNKESKIEFSNLSSEYDELVNEIIESKEINQL
VVKVFKEKRSYWKTIETKKFNIDMQIFPIKQDNSLIGIYIQALNKLEDISSIKMTSKVVHVPIIGDSPYAETLRETVHQF
AQANENILITGEQSTGKMTIAKAIHFATFGQDAPMLVVDCSSIKEGIQNLVEKVQMIQHGTIVFKEIDRLSIKEQELLVN
LVQNTPSSFQIISLSEQDLDSMLEAELFNSDLYHLISELSFYTKPLRERKEDIAAFISYFLSEFHTHSGNETLGIRKSSI
DMLKEFEWHGNLGELQRRVKELSIKATGYYINEDHIIELSERKDKQKKNDLMDRDNYISIKGTLEEIEQAIIHKVYEDEN
RNQTKTAKRLGINRTTLWRKLNNT

Sequences:

>Translated_584_residues
MIKTMLIAPYSGMAESVKQLKLPEDFQVDIEIANLEDAIQLAKSVEDQGYDLIISRGGTAAMIQEKVSIPVIHIDISGYD
MLRVFTLIQDTHHRVALVGFENISRGAKTLSSILEYEIEMFTISHRDQVRSQLEELKRLGYTIVIGDVVTVEEAQKLGIR
GILITSGKEAILDAFDEGRRQYQLLKRAHARVSRYHQILQSIPSNIILVNKESKIEFSNLSSEYDELVNEIIESKEINQL
VVKVFKEKRSYWKTIETKKFNIDMQIFPIKQDNSLIGIYIQALNKLEDISSIKMTSKVVHVPIIGDSPYAETLRETVHQF
AQANENILITGEQSTGKMTIAKAIHFATFGQDAPMLVVDCSSIKEGIQNLVEKVQMIQHGTIVFKEIDRLSIKEQELLVN
LVQNTPSSFQIISLSEQDLDSMLEAELFNSDLYHLISELSFYTKPLRERKEDIAAFISYFLSEFHTHSGNETLGIRKSSI
DMLKEFEWHGNLGELQRRVKELSIKATGYYINEDHIIELSERKDKQKKNDLMDRDNYISIKGTLEEIEQAIIHKVYEDEN
RNQTKTAKRLGINRTTLWRKLNNT
>Mature_584_residues
MIKTMLIAPYSGMAESVKQLKLPEDFQVDIEIANLEDAIQLAKSVEDQGYDLIISRGGTAAMIQEKVSIPVIHIDISGYD
MLRVFTLIQDTHHRVALVGFENISRGAKTLSSILEYEIEMFTISHRDQVRSQLEELKRLGYTIVIGDVVTVEEAQKLGIR
GILITSGKEAILDAFDEGRRQYQLLKRAHARVSRYHQILQSIPSNIILVNKESKIEFSNLSSEYDELVNEIIESKEINQL
VVKVFKEKRSYWKTIETKKFNIDMQIFPIKQDNSLIGIYIQALNKLEDISSIKMTSKVVHVPIIGDSPYAETLRETVHQF
AQANENILITGEQSTGKMTIAKAIHFATFGQDAPMLVVDCSSIKEGIQNLVEKVQMIQHGTIVFKEIDRLSIKEQELLVN
LVQNTPSSFQIISLSEQDLDSMLEAELFNSDLYHLISELSFYTKPLRERKEDIAAFISYFLSEFHTHSGNETLGIRKSSI
DMLKEFEWHGNLGELQRRVKELSIKATGYYINEDHIIELSERKDKQKKNDLMDRDNYISIKGTLEEIEQAIIHKVYEDEN
RNQTKTAKRLGINRTTLWRKLNNT

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=393, Percent_Identity=25.4452926208651, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788550, Length=311, Percent_Identity=25.08038585209, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1789233, Length=320, Percent_Identity=24.375, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1786524, Length=341, Percent_Identity=25.5131964809384, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87082152, Length=244, Percent_Identity=25, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082117, Length=317, Percent_Identity=24.6056782334385, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1787583, Length=428, Percent_Identity=22.4299065420561, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1789087, Length=380, Percent_Identity=22.3684210526316, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790299, Length=328, Percent_Identity=21.6463414634146, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI87081858, Length=440, Percent_Identity=21.3636363636364, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788905, Length=314, Percent_Identity=23.2484076433121, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 66930; Mature: 66930

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKTMLIAPYSGMAESVKQLKLPEDFQVDIEIANLEDAIQLAKSVEDQGYDLIISRGGTA
CCCEEEECCCCCHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHCCCCCEEEEECCCCH
AMIQEKVSIPVIHIDISGYDMLRVFTLIQDTHHRVALVGFENISRGAKTLSSILEYEIEM
HHHHHCCCCEEEEEEECCHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHE
FTISHRDQVRSQLEELKRLGYTIVIGDVVTVEEAQKLGIRGILITSGKEAILDAFDEGRR
EEECCHHHHHHHHHHHHHCCCEEEEECEEEHHHHHHCCCCEEEEECCHHHHHHHHHHHHH
QYQLLKRAHARVSRYHQILQSIPSNIILVNKESKIEFSNLSSEYDELVNEIIESKEINQL
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHCHHHHHHHHHHHHHHHHHHHH
VVKVFKEKRSYWKTIETKKFNIDMQIFPIKQDNSLIGIYIQALNKLEDISSIKMTSKVVH
HHHHHHHHHHHHHHHCCEEEEEEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHEEEE
VPIIGDSPYAETLRETVHQFAQANENILITGEQSTGKMTIAKAIHFATFGQDAPMLVVDC
EEEECCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCCCCCCEEEEEH
SSIKEGIQNLVEKVQMIQHGTIVFKEIDRLSIKEQELLVNLVQNTPSSFQIISLSEQDLD
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECHHHHH
SMLEAELFNSDLYHLISELSFYTKPLRERKEDIAAFISYFLSEFHTHSGNETLGIRKSSI
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECEEHHHH
DMLKEFEWHGNLGELQRRVKELSIKATGYYINEDHIIELSERKDKQKKNDLMDRDNYISI
HHHHHHHCCCCHHHHHHHHHHHEEEEEEEEECCCCEEEEHHHHHHHHHHHCCCCCCEEEE
KGTLEEIEQAIIHKVYEDENRNQTKTAKRLGINRTTLWRKLNNT
ECCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHCCC
>Mature Secondary Structure
MIKTMLIAPYSGMAESVKQLKLPEDFQVDIEIANLEDAIQLAKSVEDQGYDLIISRGGTA
CCCEEEECCCCCHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHCCCCCEEEEECCCCH
AMIQEKVSIPVIHIDISGYDMLRVFTLIQDTHHRVALVGFENISRGAKTLSSILEYEIEM
HHHHHCCCCEEEEEEECCHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHE
FTISHRDQVRSQLEELKRLGYTIVIGDVVTVEEAQKLGIRGILITSGKEAILDAFDEGRR
EEECCHHHHHHHHHHHHHCCCEEEEECEEEHHHHHHCCCCEEEEECCHHHHHHHHHHHHH
QYQLLKRAHARVSRYHQILQSIPSNIILVNKESKIEFSNLSSEYDELVNEIIESKEINQL
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHCHHHHHHHHHHHHHHHHHHHH
VVKVFKEKRSYWKTIETKKFNIDMQIFPIKQDNSLIGIYIQALNKLEDISSIKMTSKVVH
HHHHHHHHHHHHHHHCCEEEEEEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHEEEE
VPIIGDSPYAETLRETVHQFAQANENILITGEQSTGKMTIAKAIHFATFGQDAPMLVVDC
EEEECCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCCCCCCEEEEEH
SSIKEGIQNLVEKVQMIQHGTIVFKEIDRLSIKEQELLVNLVQNTPSSFQIISLSEQDLD
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECHHHHH
SMLEAELFNSDLYHLISELSFYTKPLRERKEDIAAFISYFLSEFHTHSGNETLGIRKSSI
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECEEHHHH
DMLKEFEWHGNLGELQRRVKELSIKATGYYINEDHIIELSERKDKQKKNDLMDRDNYISI
HHHHHHHCCCCHHHHHHHHHHHEEEEEEEEECCCCEEEEHHHHHHHHHHHCCCCCCEEEE
KGTLEEIEQAIIHKVYEDENRNQTKTAKRLGINRTTLWRKLNNT
ECCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]